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All Outputs (102)

The WWHIDE Framework (Web-based Workforce Health Intervention Development and Evaluation): developing a guide for workplace web-based trials (2024)
Presentation / Conference Contribution
Blake, H., Chaplin, W., Hassard, J., & Thomson, L. (2024, September). The WWHIDE Framework (Web-based Workforce Health Intervention Development and Evaluation): developing a guide for workplace web-based trials. Poster presented at 7th International Clinical Trials Methodology Conference (ICTMC) 2024, Edinburgh, Scotland

A qualitative study exploring how vocational rehabilitation for people with multiple sclerosis can be integrated within existing healthcare services in the United Kingdom (2024)
Journal Article
De Dios Perez, B., Booth, V., das Nair, R., Evangelou, N., Hassard, J., Ford, H. L., Newsome, I., & Radford, K. (2024). A qualitative study exploring how vocational rehabilitation for people with multiple sclerosis can be integrated within existing healthcare services in the United Kingdom. BMC Health Services Research, 24, Article 995. https://doi.org/10.1186/s12913-024-11424-y

Background To explore how a vocational rehabilitation (VR) intervention can be integrated within existing healthcare services for people with multiple sclerosis (MS) in the United Kingdom (UK) National Health Service (NHS). Methods Data from 37... Read More about A qualitative study exploring how vocational rehabilitation for people with multiple sclerosis can be integrated within existing healthcare services in the United Kingdom.

Comorbidities and Angiogenic Regulators Affect Endothelial Progenitor Cell Subtype Numbers in a Healthy Volunteer Control Group (2024)
Journal Article
Rakkar, K., Kadir, R. R. A., Othman, O. A., Sprigg, N., Bath, P. M., & Bayraktutan, U. (2024). Comorbidities and Angiogenic Regulators Affect Endothelial Progenitor Cell Subtype Numbers in a Healthy Volunteer Control Group. Stem Cell Reviews and Reports, https://doi.org/10.1007/s12015-024-10777-5

Endothelial progenitor cells (EPCs) are stem cells that can repair injured blood vessels through neovascularisation. This is achieved through secretion of growth factors and endothelial maturation. EPC numbers and function have been studied to determ... Read More about Comorbidities and Angiogenic Regulators Affect Endothelial Progenitor Cell Subtype Numbers in a Healthy Volunteer Control Group.

Outcome 1 year after ICH: Data from the Tranexamic acid for IntraCerebral Haemorrhage 2 (TICH-2) trial (2024)
Journal Article
Law, Z. K., Menon, C. S., Woodhouse, L. J., Appleton, J. P., Al-Shahi Salman, R., Robinson, T., Werring, D., Roffe, C., Dineen, R. A., Bath, P. M., & Sprigg, N. (2024). Outcome 1 year after ICH: Data from the Tranexamic acid for IntraCerebral Haemorrhage 2 (TICH-2) trial. European Stroke Journal, https://doi.org/10.1177/23969873241265939

Introduction: The Tranexamic acid for IntraCerebral Haemorrhage-2 (TICH-2) trial reported no significant improvement in death and dependency at day 90 despite reductions in haematoma expansion, early neurological deterioration and early death. Howev... Read More about Outcome 1 year after ICH: Data from the Tranexamic acid for IntraCerebral Haemorrhage 2 (TICH-2) trial.

Creating a health informatics data resource for hearing health research (2024)
Journal Article
Mehta, N., Ribeyre, B. B., Dimitrov, L., English, L. J., Ewart, C., Heinrich, A., Joshi, N., Munro, K. J., Roadknight, G., Romao, L., Schilder, A. G., Spriggs, R. V., Norris, R., Ross, T., & Tilston, G. (2024). Creating a health informatics data resource for hearing health research. BMC Medical Informatics and Decision Making, 24(1), Article 209. https://doi.org/10.1186/s12911-024-02589-x

Background The National Institute of Health and Social Care Research (NIHR) Health Informatics Collaborative (HIC) for Hearing Health has been established in the UK to curate routinely collected hearing health data to address research questions. Thi... Read More about Creating a health informatics data resource for hearing health research.

Manager–Team (Dis)agreement on Stress-Preventive Behaviours: Relationship with Psychosocial Work Environment and Employees’ Well-Being (2024)
Journal Article
Toderi, S., Cioffi, G., Yarker, J., Lewis, R., Houdmont, J., & Balducci, C. (2024). Manager–Team (Dis)agreement on Stress-Preventive Behaviours: Relationship with Psychosocial Work Environment and Employees’ Well-Being. International Journal of Environmental Research and Public Health, 21(8), Article 989. https://doi.org/10.3390/ijerph21080989

The “Management Competencies to Prevent and Reduce Stress at Work” (MCPARS) approach focuses on identifying the stress-preventive managers’ competencies able to optimise the employees’ well-being through the management of the psychosocial work enviro... Read More about Manager–Team (Dis)agreement on Stress-Preventive Behaviours: Relationship with Psychosocial Work Environment and Employees’ Well-Being.

Neuromodulation Treatments Targeting Pathological Synchrony for Tinnitus in Adults: A Systematic Review (2024)
Journal Article
Hoare, D. J., Shorter, G. W., Shekhawat, G. S., El Refaie, A., Labree, B., & Sereda, M. (2024). Neuromodulation Treatments Targeting Pathological Synchrony for Tinnitus in Adults: A Systematic Review. Brain Sciences, 14(8), Article 748. https://doi.org/10.3390/brainsci14080748

(1) Background: Tinnitus involves the conscious awareness of a tonal or composite noise for which there is no identifiable corresponding external acoustic source. For many people, tinnitus is a disorder associated with symptoms of emotional distress,... Read More about Neuromodulation Treatments Targeting Pathological Synchrony for Tinnitus in Adults: A Systematic Review.

Feasibility of whole-body MRI for cancer screening in children and young people with ataxia telangiectasia: A mixed methods cross-sectional study (2024)
Journal Article
Neves, R., Panek, R., Clarkson, K., Wilne, S., Panagioti, O., Suri, M., Whitehouse, W. P., Fernandez, N. S., Dandapani, M., Glazebrook, C., Dineen, R. A., & Jagani, S. (2024). Feasibility of whole-body MRI for cancer screening in children and young people with ataxia telangiectasia: A mixed methods cross-sectional study. Cancer Medicine, 13(14), Article e70049. https://doi.org/10.1002/cam4.70049

Background/Objectives: Ataxia telangiectasia (A‐T) is an inherited multisystem disorder with increased sensitivity to ionising radiation and elevated cancer risk. Although other cancer predisposition syndromes have established cancer screening protoc... Read More about Feasibility of whole-body MRI for cancer screening in children and young people with ataxia telangiectasia: A mixed methods cross-sectional study.

Expanding our understanding of long‐term trends in alcohol abstention and consumption in England (2001–19) using two age–period–cohort approaches (2024)
Journal Article
Opazo Breton, M., Henney, M., Kersbergen, I., Brennan, A., & Holmes, J. (2024). Expanding our understanding of long‐term trends in alcohol abstention and consumption in England (2001–19) using two age–period–cohort approaches. Addiction, https://doi.org/10.1111/add.16599

Background and aims: Alcohol consumption has decreased in England in recent decades, while alcohol‐specific death rates have remained relatively stable. Age–period–cohort (APC) models offer the potential for understanding these paradoxical trends. Th... Read More about Expanding our understanding of long‐term trends in alcohol abstention and consumption in England (2001–19) using two age–period–cohort approaches.

“Going through life on hard mode”- The experience of late diagnosis of autism and/or ADHD: a qualitative study (2024)
Journal Article
French, B., & Cassidy, S. (2024). “Going through life on hard mode”- The experience of late diagnosis of autism and/or ADHD: a qualitative study. Autism in Adulthood, https://doi.org/10.1089/aut.2024.0085

Background – In the UK, over 2.5 million adults with undiagnosed neurodevelopmental conditions, such as autism and ADHD, can face difficulties accessing diagnosis and support. Our qualitative study explores people’s experiences of receiving a diagnos... Read More about “Going through life on hard mode”- The experience of late diagnosis of autism and/or ADHD: a qualitative study.

A qualitative study of the views of ethnic minority healthcare workers towards COVID-19 Vaccine Education (CoVE) to support vaccine promotion and uptake (2024)
Journal Article
Blake, H., Premakumar, V., Premakumar, A., Fecowycz, A., Khulumula, S. K., Jones, W., & Somerset, S. (in press). A qualitative study of the views of ethnic minority healthcare workers towards COVID-19 Vaccine Education (CoVE) to support vaccine promotion and uptake. New Solutions: A Journal of Environmental and Occupational Health Policy,

Snakes and Ladders: The experience of being referred to and seen by Child and Adolescent Mental Health Services (2024)
Journal Article
Newman, K. L., Sayal, K., Ewart, C., Lang, A., Bhardwaj, A., Dubicka, B., Marshall, T., & Thomson, L. (2024). Snakes and Ladders: The experience of being referred to and seen by Child and Adolescent Mental Health Services. SSM - Mental Health, 6, Article 100343. https://doi.org/10.1016/j.ssmmh.2024.100343

Background: Referral processes in Child and Adolescent Mental Health Services (CAMHS) have been reported as stressful and inadequate by young people and parents/carers, who struggle during waiting periods for the referral outcome decision. The Covid1... Read More about Snakes and Ladders: The experience of being referred to and seen by Child and Adolescent Mental Health Services.

The relationship between line manager training in mental health and organisational outcomes (2024)
Journal Article
Hassard, J., Dulal-Arthur, T., Bourke, J., Wishart, M., Roper, S., Belt, V., Leka, S., Pahl, N., Bartle, C., Thomson, L., & Blake, H. (2024). The relationship between line manager training in mental health and organisational outcomes. PLoS ONE, 19(7), Article e0306065. https://doi.org/10.1371/journal.pone.0306065

Background: Line manager (LM) training in mental health is gaining recognition as an effective method for improving the mental health and wellbeing of workers. However, research predominantly focuses on the impacts of training at the employee-level,... Read More about The relationship between line manager training in mental health and organisational outcomes.

Research into digital health intervention for mental health: a 25-year retrospective on the ethical and legal challenges (2024)
Journal Article
Hall, C. L., Gómez Bergin, A. D., & Rennick-Egglestone, S. (in press). Research into digital health intervention for mental health: a 25-year retrospective on the ethical and legal challenges. Journal of Medical Internet Research, https://doi.org/10.2196/58939

Digital mental health interventions are routinely integrated into mental health services internationally, and can contribute to the reduction of the global mental health treatment gap that has been identified by the World Health Organisation. Researc... Read More about Research into digital health intervention for mental health: a 25-year retrospective on the ethical and legal challenges.

What affects implementation of the UK major trauma rehabilitation prescription? A survey informed by the behaviour change wheel (2024)
Journal Article
Kettlewell, J., Radford, K., Timmons, S., Jones, T., Fallon, S., Westley, R., White, S., & Kendrick, D. (2024). What affects implementation of the UK major trauma rehabilitation prescription? A survey informed by the behaviour change wheel. Injury, Article 111722. https://doi.org/10.1016/j.injury.2024.111722

Objective: Major trauma 'Rehabilitation Prescriptions' aim to facilitate continuity of care and describe patient needs following discharge from UK Major Trauma Centre (MTCs), however research suggests rehabilitation prescriptions are not being implem... Read More about What affects implementation of the UK major trauma rehabilitation prescription? A survey informed by the behaviour change wheel.

Line manager training and organizational approaches to supporting well-being. (2024)
Journal Article
Dulal-Arthur, T., Hassard, J., Bourke, J., Roper, S., Wishart, M., Belt, V., Bartle, C., Leka, S., Pahl, N., Thomson, L., & Blake, H. (2024). Line manager training and organizational approaches to supporting well-being. Occupational Medicine, https://doi.org/10.1093/occmed/kqae051

Employee mental health and well-being (MH&WB) is critical to the productivity and success of organizations. Training line managers (LMs) in mental health plays an important role in protecting and enhancing employee well-being, but its relationship wi... Read More about Line manager training and organizational approaches to supporting well-being..

Development of a Vocational Rehabilitation Intervention to support Return to Work and Wellbeing following Major Trauma: A Person-Based Approach (2024)
Journal Article
Radford, K., Kettlewell, J., das Nair, R., Morriss, R., Holmes, J., Kellezi, B., Timmons, S., Jones, T., Tressider, H., Andrews, I., Bridger, K., Patel, P., Lindley, R., De Dios Perez, B., Statham, A., Jones, T., Hoffman, K., James, M., Kendrick, D., & ROWTATE study team. (in press). Development of a Vocational Rehabilitation Intervention to support Return to Work and Wellbeing following Major Trauma: A Person-Based Approach. BMJ Open,

Objectives: Major trauma centres save lives but rehabilitation to support return-to-work (RTW) is lacking. This paper describes development of a vocational rehabilitation intervention (the ROWTATE intervention) to support RTW following traumatic inju... Read More about Development of a Vocational Rehabilitation Intervention to support Return to Work and Wellbeing following Major Trauma: A Person-Based Approach.

Categorising interventions to enhance vaccine uptake or reduce vaccine hesitancy in the United Kingdom: A systematic review and meta-analysis (2024)
Journal Article
Kafadar, A. H., Sabatini, S., Jones, K. A., & Dening, T. (2024). Categorising interventions to enhance vaccine uptake or reduce vaccine hesitancy in the United Kingdom: A systematic review and meta-analysis. Vaccine, https://doi.org/10.1016/j.vaccine.2024.06.059

Background: Vaccination is one of the most important public health interventions to combat infectious disease. However, vaccine hesitancy prevents us reaching the global target of vaccine uptake (e.g., 75 % of influenza vaccination in at-risk groups)... Read More about Categorising interventions to enhance vaccine uptake or reduce vaccine hesitancy in the United Kingdom: A systematic review and meta-analysis.

Defining the disturbance in cortical glutamate and GABA function in psychosis and its origins and consequences (2024)
Preprint / Working Paper
Deakin, B., Liddle, E., Rathnaiah, M., Gregory, C., Katshu, M., Wiliams, G., Conen, S., Smallman, R., Koelewijn, L. C., Anton, A., Kumar, J., Gasgoyne, L. E., Chen, C., Nikkheslat, N., Evans, J., Lanz, B., Walters, J., Talbot, P., Palaniyappan, L., Singh, K. D., …Liddle, P. F. Defining the disturbance in cortical glutamate and GABA function in psychosis and its origins and consequences

It is widely thought that the onset of psychotic symptoms in schizophrenia may arise from an early neurotoxic phase, possibly related to oxidative stress or inflammation, and a late residual damage phase associated with persistent negative symptoms.... Read More about Defining the disturbance in cortical glutamate and GABA function in psychosis and its origins and consequences.