Research Repository

See what's under the surface


A systematic review of the literature describing the outcomes of near-peer mentoring programs for first year medical students (2018)
Journal Article
Akinla, O., Hagan, P., & Atiomo, W. (2018). A systematic review of the literature describing the outcomes of near-peer mentoring programs for first year medical students. BMC Medical Education, 18, doi:10.1186/s12909-018-1195-1. ISSN 1472-6920

Background Transition into higher education has been identified as one of the most stressful periods for learners. Interventions targeting the transition phase such as near- peer mentoring might help address some of these challenges. We were however... Read More

A BEME systematic review of UK undergraduate medical education in the general practice setting: BEME Guide No. 32 (2015)
Journal Article
Hampshire, M., Park, S., Khan, N. F., KNOX, R., Malpass, A., Thomas, J., …Georgieva, Z. (2015). A BEME systematic review of UK undergraduate medical education in the general practice setting: BEME Guide No. 32. Medical Teacher, 37(7), 611-630. doi:10.3109/0142159X.2015.1032918

Background: General practice is increasingly used as a learning environment in undergraduate medical education in the UK. Aim: The aim of this project was to identify, summarise and synthesise research about undergraduate medical education in gene... Read More

Auditory network connectivity in tinnitus patients: a resting-state fMRI study (2014)
Journal Article
Davies, J., Gander, P. E., Andrews, M., & Hall, D. A. (2014). Auditory network connectivity in tinnitus patients: a resting-state fMRI study. International Journal of Audiology, 53(3), doi:10.3109/14992027.2013.846482

Objective: Resting-state functional magnetic resonance imaging (fMRI) uncovers correlated activity between spatially distinct functionally related brain regions and offers clues about the integrity of functional brain circuits in people with chronic... Read More

Novel function for the p38-MK2 signaling pathway in circulating CD1c+ (BDCA-1+) myeloid dendritic cells from healthy donors and advanced cancer patients; inhibition of p38 enhances IL-12 whilst suppressing IL-10 (2014)
Journal Article
Franks, H. A., Wang, Q., Lax, S. J., Colllins, M. K., Escors, D., Patel, P. M., & Jackson, A. M. (2014). Novel function for the p38-MK2 signaling pathway in circulating CD1c+ (BDCA-1+) myeloid dendritic cells from healthy donors and advanced cancer patients; inhibition of p38 enhances IL-12 whilst suppressing IL-10. International Journal of Cancer, 134(3), doi:10.1002/ijc.28398

There is growing interest in myeloid (my) dendritic cells (DC) as an alternative to monocyte-derived DC (moDC) for immunotherapy. However, in contrast to moDC, little is known regarding the effect of malignancy on the function, abundance or use of in... Read More

When is birthweight at term abnormally low?: a systematic review and meta-analysis of the association and predictive ability of current birthweight standards for neonatal outcomes (2014)
Journal Article
Malin, G., Morris, R., Riley, R., Teune, M., & Khan, K. (2014). When is birthweight at term abnormally low?: a systematic review and meta-analysis of the association and predictive ability of current birthweight standards for neonatal outcomes. BJOG: An International Journal of Obstetrics and Gynaecology, 121(5), doi:10.1111/1471-0528.12517

Background Intrauterine growth restriction is a cause of neonatal morbidity and mortality. A variety of definitions of low birthweight are used in clinical practice, with a lack of consensus regarding which definitions best predict adverse outcomes.... Read More

The prevalence of tinnitus and the relationship with neuroticism in a middle-aged UK population (2014)
Journal Article
McCormack, A., Edmondson-Jones, M., Fortnum, H., Dawes, P., Middleton, H., Munro, K. J., & Moore, D. R. (2014). The prevalence of tinnitus and the relationship with neuroticism in a middle-aged UK population. Journal of Psychosomatic Research, 76(1), doi:10.1016/j.jpsychores.2013.08.018

Background: Previous research has suggested that a substantial proportion of the population are severely affected by tinnitus, however recent population data are lacking. Furthermore, there is growing evidence that the perception of severity is close... Read More

The Cochrane Skin Group: a vanguard for developing and promoting evidence-based dermatology (2013)
Journal Article
Reddi, A., Prescott, L., Doney, E., Delamere, F., Kollipara, R., Dellavalle, R. P., & Williams, H. C. (2013). The Cochrane Skin Group: a vanguard for developing and promoting evidence-based dermatology. Journal of Evidence-Based Medicine, 6(4), doi:10.1111/jebm.12068

Aim The Cochrane Skin Group (CSG) is part of the international Cochrane Collaboration (http://www.cochrane.org/). The CSG prepares, maintains and disseminates high quality evidence-based summaries on the prevention, diagnosis and treatment of skin d... Read More

Optimised laser microdissection of the human ocular surface epithelial regions for microarray studies (2013)
Journal Article
Kulkarn, B. B. .., Powe, D. G., Hopkinson, A., & Dua, H. S. (2013). Optimised laser microdissection of the human ocular surface epithelial regions for microarray studies. BMC Ophthalmology, 13, doi:10.1186/1471-2415-13-62

Background The most important challenge of performing insitu transcriptional profiling of the human ocular surface epithelial regions is obtaining samples in sufficient amounts, without contamination from adjacent tissue, as the region of interest i... Read More

Psychosocial risk assessment in organizations: concurrent validity of the brief version of the Management Standards Indicator Tool (2013)
Journal Article
Houdmont, J., Randall, R., Kerr, R., & Addley, K. (2013). Psychosocial risk assessment in organizations: concurrent validity of the brief version of the Management Standards Indicator Tool. Work and Stress, 27(4), doi:10.1080/02678373.2013.843607

The Management Standards Indicator Tool (MSIT) is a 35-item self-report measure of the psychosocial work environment designed to assist organizations with psychosocial risk assessment. It is also used in work environment research. Edwards and Webster... Read More

Tobacco smoking, associated risk behaviours, and experience with quitting: a qualitative study with homeless smokers addicted to drugs and alcohol (2013)
Journal Article
Garner, L., & Ratschen, E. (2013). Tobacco smoking, associated risk behaviours, and experience with quitting: a qualitative study with homeless smokers addicted to drugs and alcohol. BMC Public Health, 13, doi:10.1186/1471-2458-13-951

Background The prevalence of tobacco smoking among homeless people can reach more than 90%, with related morbidity and mortality being high. However, research in this area is scarce. This study aims to explore smoking and quitting related behaviours... Read More

Menopause and work: an electronic survey of employees’ attitudes in the UK (2013)
Journal Article
Griffiths, A., MacLennen, S. J., & Hassard, J. (2013). Menopause and work: an electronic survey of employees’ attitudes in the UK. Maturitas, 76(2), doi:10.1016/j.maturitas.2013.07.005

Objectives: This study explored women's experiences of working through menopausal transition in the UK. It aimed to identify the perceived effects of menopausal symptoms on working life, to outline the perceived effects of work on menopausal symptoms... Read More

Development of a new SonovueTM contrast-enhanced ultrasound approach reveals temporal and age-related features of muscle microvascular responses to feeding (2013)
Journal Article
features of muscle microvascular responses to feeding. Physiological Reports, 1(5), doi:10.1002/phy2.119

Compromised limb blood flow in aging may contribute to the development of sarcopenia, frailty, and the metabolic syndrome. We developed a novel contrast-enhanced ultrasound technique using Sonovue™ to characterize muscle microvasculature responses to... Read More

Circulating antibody and memory B-cell responses to C. difficile toxins A and B in patients with C. difficile- associated diarrhoea, inflammatory bowel disease and cystic fibrosis (2013)
Journal Article
Monaghan, T. M., Robins, A., Knox, A., Sewell, H. F., & Mahida, Y. R. (2013). Circulating antibody and memory B-cell responses to C. difficile toxins A and B in patients with C. difficile- associated diarrhoea, inflammatory bowel disease and cystic fibrosis. PLoS ONE, 8(9), doi:10.1371/journal.pone.0074452

C. difficile infection (CDI) is rarely reported in cystic fibrosis (CF) patients despite frequent hospitalisations and antibiotic usage. Conversely, the prevalence of CDI in inflammatory bowel disease (IBD) has received increased attention. We inve... Read More

Validating excised rodent lungs for functional hyperpolarized xenon-129 MRI (2013)
Journal Article
hyperpolarized xenon-129 MRI. PLoS ONE, 8(8), doi:10.1371/journal.pone.0073468

Ex vivo rodent lung models are explored for physiological measurements of respiratory function with hyperpolarized (hp) 129Xe MRI. It is shown that excised lung models allow for simplification of the technical challenges involved and provide valuable... Read More

Neural primacy of the salience processing system in schizophrenia (2013)
Journal Article
Palaniyappan, L., Simmonite, M., White, T., Liddle, E., & Liddle, P. (2013). Neural primacy of the salience processing system in schizophrenia. Neuron, 79(4), doi:10.1016/j.neuron.2013.06.027

For effective information processing, two large-scale distributed neural networks appear to be critical: a multimodal executive system anchored on the dorsolateral prefrontal cortex (DLPFC) and a salience system anchored on the anterior insula. Aberr... Read More

A survey of tobacco dependence treatment guidelines in 121 countries (2013)
Journal Article
Piné-Abata, H., McNeill, A., Raw, M., Bitton, A., Rigotti, N., & Murray, R. (2013). A survey of tobacco dependence treatment guidelines in 121 countries. Addiction, 108(8), doi:10.1111/add.12158

Aims To report progress among Parties to the World Health Organization (WHO) Framework Convention on Tobacco Control (FCTC) in developing national tobacco treatment guidelines in accordance with FCTC Article 14 guideline recommendations. Design... Read More

Coordinate based meta-analysis of functional neuroimaging data: false discovery control and diagnostics (2013)
Journal Article
Tench, C. R., Tanasescu, R., Auer, D. P., & Constantinescu, C. S. (2013). Coordinate based meta-analysis of functional neuroimaging data: false discovery control and diagnostics. PLoS ONE, 8(7), doi:10.1371/journal.pone.0070143

Coordinate based meta-analysis (CBMA) is widely used to find regions of consistent activation across fMRI studies that have been selected for their functional relevance to a given hypothesis. Only reported coordinates (foci), and a model of their spa... Read More

HTR4 gene structure and altered expression in the developing lung (2013)
Journal Article
Hodge, E., Nelson, C. P., Miller, S., Billington, C. K., Stewart, C. E., Swan, C., …Sayers, I. (2013). HTR4 gene structure and altered expression in the developing lung. Respiratory Research, 14(77), doi:10.1186/1465-9921-14-77

Background: Meta-analyses of genome-wide association studies (GWAS) have identified single nucleotide polymorphisms (SNPs) spanning the 5-hydroxytryptamine receptor 4 (5-HT4R) gene (HTR4) associated with lung function. The aims of this study were t... Read More

‘Mind the gap’ - mapping services for young people with ADHD transitioning from child to adult mental health services (2013)
Journal Article
Hall, C. L., Newell, K., Taylor, J., Sayal, K., Swift, K. D., & Hollis, C. (2013). ‘Mind the gap’ - mapping services for young people with ADHD transitioning from child to adult mental health services. BMC Psychiatry, 13(186), doi:10.1186/1471-244X-13-186

Background: Once considered to be a disorder restricted to childhood, Attention Deficit/Hyperactivity Disorder (ADHD) is now recognised to persist into adult life. However, service provision for adults with ADHD is limited. Additionally, there is lit... Read More