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Foot and ankle Osteoarthritis and Cognitive impairment in retired UK Soccer players (FOCUS): protocol for a cross-sectional comparative study with general population controls (2022)
Journal Article
Espahbodi, S., Fernandes, G., Hogervorst, E., Thanoon, A., Batt, M., Fuller, C. W., …Zhang, W. (2022). Foot and ankle Osteoarthritis and Cognitive impairment in retired UK Soccer players (FOCUS): protocol for a cross-sectional comparative study with general population controls. BMJ Open, 12(4), Article e054371. https://doi.org/10.1136/bmjopen-2021-054371

INTRODUCTION: Professional footballers commonly experience sports-related injury and repetitive microtrauma to the foot and ankle, placing them at risk of subsequent chronic pain and osteoarthritis (OA) of the foot and ankle. Similarly, repeated head... Read More about Foot and ankle Osteoarthritis and Cognitive impairment in retired UK Soccer players (FOCUS): protocol for a cross-sectional comparative study with general population controls.

The association of socio-economic and psychological factors with limitations in day-to-day activity over 7 years in newly diagnosed osteoarthritis patients (2022)
Journal Article
Kouraki, A., Bast, T., Ferguson, E., & Valdes, A. M. (2022). The association of socio-economic and psychological factors with limitations in day-to-day activity over 7 years in newly diagnosed osteoarthritis patients. Scientific Reports, 12(1), Article 943. https://doi.org/10.1038/s41598-022-04781-3

Previous research has established links between chronic pain and impaired cognitive ability, as well as between chronic pain and anxiety, in osteoarthritis. Furthermore, there is evidence linking risk of osteoarthritis to lower educational attainment... Read More about The association of socio-economic and psychological factors with limitations in day-to-day activity over 7 years in newly diagnosed osteoarthritis patients.

Central Aspects of Pain in Rheumatoid Arthritis (CAP-RA): protocol for a prospective observational study (2021)
Journal Article
Ifesemen, O., McWilliams, D. F., Ferguson, E., Wakefield, R., Akin-Akinyosoye, K., Wilson, D., …Walsh, D. A. (2021). Central Aspects of Pain in Rheumatoid Arthritis (CAP-RA): protocol for a prospective observational study. BMC Rheumatology, 5(1), Article 23. https://doi.org/10.1186/s41927-021-00187-2

Background: Pain and fatigue are persistent problems in people with rheumatoid arthritis. Central sensitisation (CS) may contribute to pain and fatigue, even when treatment has controlled inflammatory disease. This study aims to validate a self-repor... Read More about Central Aspects of Pain in Rheumatoid Arthritis (CAP-RA): protocol for a prospective observational study.

Using heterogeneity in disease to understand the relationship between health and personality (2021)
Journal Article
James, R., Walsh, D., & Ferguson, E. (2022). Using heterogeneity in disease to understand the relationship between health and personality. Psychology, Health and Medicine, 27(7), 1582-1595. https://doi.org/10.1080/13548506.2021.1903057

The aim of this study was to compare the relationship between two health outcomes (pain and self-reported health) and personality while accounting for heterogeneity in arthritic disease. Traditionally health psychology and other health research has t... Read More about Using heterogeneity in disease to understand the relationship between health and personality.

The Central Aspects of Pain in the Knee (CAP-Knee) questionnaire; a mixed-methods study of a self-report instrument for assessing central mechanisms in people with knee pain (2021)
Journal Article
Akin-Akinyosoye, K., James, R. J. E., Mcwilliams, D. F., Millar, B., Das Nair, R., Ferguson, E., & Walsh, D. A. (2021). The Central Aspects of Pain in the Knee (CAP-Knee) questionnaire; a mixed-methods study of a self-report instrument for assessing central mechanisms in people with knee pain. Osteoarthritis and Cartilage, 29(6), 802-814. https://doi.org/10.1016/j.joca.2021.02.562

OBJECTIVES: Pain is the prevailing symptom of knee osteoarthritis. Central sensitisation creates discordance between pain and joint pathology. We previously reported a central pain mechanisms trait derived from 8 discrete characteristics: neuropathic... Read More about The Central Aspects of Pain in the Knee (CAP-Knee) questionnaire; a mixed-methods study of a self-report instrument for assessing central mechanisms in people with knee pain.

Investigating musculoskeletal health and wellbeing; A cohort study protocol (2020)
Journal Article
Millar, B., McWilliams, D. F., Abhishek, A., Akin-Akinyosoye, K., Auer, D. P., Chapman, V., …Walsh, D. A. (2020). Investigating musculoskeletal health and wellbeing; A cohort study protocol. BMC Musculoskeletal Disorders, 21(1), Article 182. https://doi.org/10.1186/s12891-020-03195-4

© 2020 The Author(s). Background: In an ageing population, pain, frailty and disability frequently coexist across a wide range of musculoskeletal diagnoses, but their associations remain incompletely understood. The Investigating Musculoskeletal Heal... Read More about Investigating musculoskeletal health and wellbeing; A cohort study protocol.

Baseline self-report ‘central mechanisms’ trait predicts persistent knee pain in the Knee Pain in the Community (KPIC) cohort (2019)
Journal Article
Akin-Akinyosoye, K., Sarmanova, A., Fernandes, G., Frowd, N., Swaithes, L., Stocks, J., …Walsh, D. A. (2020). Baseline self-report ‘central mechanisms’ trait predicts persistent knee pain in the Knee Pain in the Community (KPIC) cohort. Osteoarthritis and Cartilage, 28(2), 173-181. https://doi.org/10.1016/j.joca.2019.11.004

Objectives We investigated whether baseline scores for a self-report trait linked to central mechanisms predict 1 year pain outcomes in the Knee Pain in the Community cohort. Method 1471 participants reported knee pain at baseline and respon... Read More about Baseline self-report ‘central mechanisms’ trait predicts persistent knee pain in the Knee Pain in the Community (KPIC) cohort.

Baseline self-report ‘central mechanisms’ trait predicts persistent knee pain in the Knee Pain in the Community (KPIC) cohort (2019)
Journal Article
Akin-Akinyosoye, K., Sarmanova, A., Fernandes, G. S., Frowd, N., Swaithes, L., Stocks, J., …Walsh, D. A. (2020). Baseline self-report ‘central mechanisms’ trait predicts persistent knee pain in the Knee Pain in the Community (KPIC) cohort. Osteoarthritis and Cartilage, 28(2), 173-181. https://doi.org/10.1016/j.joca.2019.11.004

© 2019 The Authors Objectives: We investigated whether baseline scores for a self-report trait linked to central mechanisms predict 1 year pain outcomes in the Knee Pain in the Community cohort. METHOD: 1471 participants reported knee pain at baselin... Read More about Baseline self-report ‘central mechanisms’ trait predicts persistent knee pain in the Knee Pain in the Community (KPIC) cohort.

Disease Activity Flares and Pain Flares in an early rheumatoid arthritis inception cohort; characteristics, antecedents and sequelae (2019)
Journal Article
McWilliams, D. F., Rahman, S., James, R., Ferguson, E., Kiely, P., Young, A., & Walsh, D. (2019). Disease Activity Flares and Pain Flares in an early rheumatoid arthritis inception cohort; characteristics, antecedents and sequelae. BMC Rheumatology, 3, 1-9. https://doi.org/10.1186/s41927-019-0100-9

Background RA flares are common and disabling. They are described in terms of worsening inflammation but pain and inflammation are often discordant. To inform treatment decisions, we investigated whether inflammatory and pain flares are discrete ent... Read More about Disease Activity Flares and Pain Flares in an early rheumatoid arthritis inception cohort; characteristics, antecedents and sequelae.

Disease Activity Flares and Pain Flares in an early rheumatoid arthritis inception cohort; characteristics, antecedants and sequelae (2019)
Presentation / Conference
McWilliams, D., Rahman, S., James, R., Ferguson, E., Kiely, P., Young, A., & Walsh, D. (2019, April). Disease Activity Flares and Pain Flares in an early rheumatoid arthritis inception cohort; characteristics, antecedants and sequelae. Poster presented at Rheumatology 2019

Background RA flares are common and disabling. They are described in terms of worsening pain, swelling, or other symptoms. We aimed to determine characteristics, antecedants and sequelae of painful and inflammatory flare subtypes during the first 11... Read More about Disease Activity Flares and Pain Flares in an early rheumatoid arthritis inception cohort; characteristics, antecedants and sequelae.

Trajectories of pain predict disabilities affecting daily living in arthritis (2019)
Journal Article
James, R. J., Walsh, D. A., & Ferguson, E. (2019). Trajectories of pain predict disabilities affecting daily living in arthritis. British Journal of Health Psychology, 24(3), 465-496. https://doi.org/10.1111/bjhp.12364

Purpose: To examine the interplay between pain and disability in arthritis when adjusting for patient heterogeneity in pain progression. There is consistent evidence to suggest that people experience osteoarthritis heterogeneously, with subgroups of... Read More about Trajectories of pain predict disabilities affecting daily living in arthritis.

Discrete trajectories of resolving and persistent pain in people with rheumatoid arthritis despite undergoing treatment for inflammation: results from three UK cohorts (2019)
Journal Article
McWilliams, D. F., Dawson, O., Young, A., Kiely, P., Ferguson, E., & Walsh, D. A. (2019). Discrete trajectories of resolving and persistent pain in people with rheumatoid arthritis despite undergoing treatment for inflammation: results from three UK cohorts. Journal of Pain, 20(6), 716-727. https://doi.org/10.1016/j.jpain.2019.01.001

Rheumatoid arthritis (RA) is an example of human chronic inflammatory pain. Modern treatments suppress inflammation, yet pain remains a major problem for many people with RA. We hypothesised that discrete RA subgroups might display favourable or unfa... Read More about Discrete trajectories of resolving and persistent pain in people with rheumatoid arthritis despite undergoing treatment for inflammation: results from three UK cohorts.

General and disease-specific pain trajectories as predictors of social and political outcomes in arthritis and cancer (2018)
Journal Article
James, R. J. E., Walsh, D. A., & Ferguson, E. (2018). General and disease-specific pain trajectories as predictors of social and political outcomes in arthritis and cancer. BMC Medicine, 16, Article 51. https://doi.org/10.1186/s12916-018-1031-9

Background: While the heterogeniety of pain progression has been studied in chronic diseases, it is unclear the extent to which patterns of pain progression among people in general as well as across different diseases impacts on social, civic and po... Read More about General and disease-specific pain trajectories as predictors of social and political outcomes in arthritis and cancer.

Traits associated with central pain augmentation in the Knee Pain in the Community (KPIC) cohort (2018)
Journal Article
Akin-Akinyosoye, K., Frowd, N., Marshall, L., Stocks, J., Fernandes, G. S., Valdes, A. M., …Walsh, D. A. (2018). Traits associated with central pain augmentation in the Knee Pain in the Community (KPIC) cohort. PAIN, 159(6), 1035–1044. https://doi.org/10.1097/j.pain.0000000000001183

This study aimed to identify self-report correlates of central pain augmentation in individuals with knee pain. A subset of participants (n=420) in the Knee Pain and related health In the Community (KPIC) baseline survey undertook pressure pain thres... Read More about Traits associated with central pain augmentation in the Knee Pain in the Community (KPIC) cohort.

Histopathological subgroups in knee osteoarthritis (2016)
Journal Article
Wyatt, L., Morerton, B., Mapp, P. I., Wilson, D., Hill, R., Ferguson, E., …Walsh, D. A. (in press). Histopathological subgroups in knee osteoarthritis. Osteoarthritis and Cartilage, 25(1), https://doi.org/10.1016/j.joca.2016.09.021

Objective: Osteoarthritis (OA) is a heterogeneous, multi-tissue disease. We hypothesised that different histopathological features characterise different stages during knee OA progression, and that discrete subgroups can be defined based on validated... Read More about Histopathological subgroups in knee osteoarthritis.