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All Outputs (558)

Developing a measure of polypharmacy appropriateness in primary care: systematic review and expert consensus study (2018)
Journal Article
Burt, J., Elmore, N., Campbell, S. M., Rodgers, S., Avery, A. J., & Payne, R. A. (2018). Developing a measure of polypharmacy appropriateness in primary care: systematic review and expert consensus study. BMC Medicine, 16, 1-15. https://doi.org/10.1186/s12916-018-1078-7

Background: Polypharmacy is an increasing challenge for primary care. Although sometimes clinically justified, polypharmacy can be inappropriate, leading to undesirable outcomes. Optimising care for polypharmacy necessitates effective targeting and m... Read More about Developing a measure of polypharmacy appropriateness in primary care: systematic review and expert consensus study.

Early risk factors for depression, anxiety and post-traumatic distress after hospital admission for unintentional injury: multicentre cohort study (2018)
Journal Article
Kendrick, D., Baker, R., Hill, T., Beckett, K., Coupland, C., Kellezi, B., …Morriss, R. (2018). Early risk factors for depression, anxiety and post-traumatic distress after hospital admission for unintentional injury: multicentre cohort study. Journal of Psychosomatic Research, 112, 15-24. https://doi.org/10.1016/j.jpsychores.2018.06.008

Objective: To quantify psychological morbidity and identify baseline factors associated with depression, anxiety and post-traumatic distress symptoms up to 12 months post-injury. Methods: Multicentre cohort study of 668 adults, aged 16 to 70,... Read More about Early risk factors for depression, anxiety and post-traumatic distress after hospital admission for unintentional injury: multicentre cohort study.

Informing evaluation of a smartphone application for people with acquired brain injury: a stakeholder engagement study (2018)
Journal Article
Kettlewell, J., Phillips, J., Radford, K. A., & das Nair, R. (2018). Informing evaluation of a smartphone application for people with acquired brain injury: a stakeholder engagement study. BMC Medical Informatics and Decision Making, 18(1), Article 33. https://doi.org/10.1186/s12911-018-0611-0

Background Brain in Hand is a smartphone application (app) that allows users to create structured diaries with problems and solutions, attach reminders, record task completion and has a symptom monitoring system. Brain in Hand was designed to supp... Read More about Informing evaluation of a smartphone application for people with acquired brain injury: a stakeholder engagement study.

Intervention planning for the REDUCE maintenance intervention: a digital intervention to reduce re-ulceration risk among patients with a history of diabetic foot ulcers (2018)
Journal Article
Greenwell, K., Sivyer, K., Vedhara, K., Yardley, L., Game, F., Chalder, T., …Bradbury, K. (2018). Intervention planning for the REDUCE maintenance intervention: a digital intervention to reduce re-ulceration risk among patients with a history of diabetic foot ulcers. BMJ Open, 8(5), https://doi.org/10.1136/bmjopen-2017-019865

Objectives: To develop a comprehensive intervention plan for the REDUCE maintenance intervention to support people who have had diabetic foot ulcers (DFUs) to sustain behaviours that reduce re-ulceration risk. Methods: Theory-, evidence- and perso... Read More about Intervention planning for the REDUCE maintenance intervention: a digital intervention to reduce re-ulceration risk among patients with a history of diabetic foot ulcers.

Cost-utility analysis of searching electronic health records and cascade testing to identify and diagnose familial hypercholesterolaemia in England and Wales (2018)
Journal Article
Crosland, P., Maconachie, R., Buckner, S., McGuire, H., Humphries, S. E., & Qureshi, N. (2018). Cost-utility analysis of searching electronic health records and cascade testing to identify and diagnose familial hypercholesterolaemia in England and Wales. Atherosclerosis, 275, https://doi.org/10.1016/j.atherosclerosis.2018.05.021

Background and aims: The cost effectiveness of cascade testing for familial hypercholesterolaemia (FH) is well recognised. Less clear is the cost effectiveness of FH screening when it includes case identification strategies that incorporate routinely... Read More about Cost-utility analysis of searching electronic health records and cascade testing to identify and diagnose familial hypercholesterolaemia in England and Wales.

Physical activity for antenatal and postnatal depression in women attempting to quit smoking: randomised controlled trial (2018)
Journal Article
Daley, A., Riaz, M., Lewis, S., Aveyard, P., Coleman, T., Manyonda, I., …Ussher, M. (2018). Physical activity for antenatal and postnatal depression in women attempting to quit smoking: randomised controlled trial. BMC Pregnancy and Childbirth, 18, https://doi.org/10.1186/s12884-018-1784-3

Background: Antenatal depression is associated with harmful consequences for both the mother and child. One intervention that might be effective is participation in regular physical activity although data on this question in pregnant smokers is curre... Read More about Physical activity for antenatal and postnatal depression in women attempting to quit smoking: randomised controlled trial.

Improving identification & management of familial hypercholesterolaemia in primary care: pre- and post-intervention study (2018)
Journal Article
Weng, S., Kai, J., Tranter, J., Leonardi-Bee, J., & Qureshi, N. (2018). Improving identification & management of familial hypercholesterolaemia in primary care: pre- and post-intervention study. Atherosclerosis, 274, 54-60. https://doi.org/10.1016/j.atherosclerosis.2018.04.037

Background and Aims: Familial hypercholesterolaemia (FH) is a major cause of premature heart disease but remains unrecognised in most patients. This study investigated if a systematic primary care-based approach to identify and manage possible FH imp... Read More about Improving identification & management of familial hypercholesterolaemia in primary care: pre- and post-intervention study.

Uptake of Tailored Text Message Smoking Cessation Support in Pregnancy When Advertised on the Internet (MiQuit): Observational Study (2018)
Journal Article
Emery, J., Coleman, T., Sutton, S., Cooper, S., Leonardi-Bee, J., Jones, M. D., & Naughton, F. (2018). Uptake of Tailored Text Message Smoking Cessation Support in Pregnancy When Advertised on the Internet (MiQuit): Observational Study. Journal of Medical Internet Research, 20(4), Article e146. https://doi.org/10.2196/jmir.8525

Background: Smoking in pregnancy is a major public health concern. Pregnant smokers are particularly difficult to reach, with low uptake of support options and few effective interventions. Text message–based self-help is a promising, low-cost interve... Read More about Uptake of Tailored Text Message Smoking Cessation Support in Pregnancy When Advertised on the Internet (MiQuit): Observational Study.

Mindful organizing in patients’ contributions to primary care medication safety (2018)
Journal Article
Phipps, D. L., Giles, S., Lewis, P. J., Marsden, K., Salema, N., Jeffries, M., …Ashcroft, D. M. (2018). Mindful organizing in patients’ contributions to primary care medication safety. Health Expectations, 21(6), 964-972. https://doi.org/10.1111/hex.12689

Background: There is a need to ensure that the risks associated with medication usage in primary healthcare are controlled. To maintain an understanding of the risks, healthcare organizations may engage in a process known as “mindful organizing”. Whi... Read More about Mindful organizing in patients’ contributions to primary care medication safety.

Does bone mineral density improve the predictive accuracy of fracture risk assessment?: a prospective cohort study in Northern Denmark (2018)
Journal Article
Dhiman, P., Andersen, S., Vestergaard, P., Masud, T., & Qureshi, N. (2018). Does bone mineral density improve the predictive accuracy of fracture risk assessment?: a prospective cohort study in Northern Denmark. BMJ Open, 8, Article e018898. https://doi.org/10.1136/bmjopen-2017-018898

Objective: To evaluate the added predictive accuracy of bone mineral density (BMD) to fracture risk assessment.Design Prospective cohort study using data between 01 January 2010 and 31 December 2012. Setting: North Denmark Osteoporosis Clinic of r... Read More about Does bone mineral density improve the predictive accuracy of fracture risk assessment?: a prospective cohort study in Northern Denmark.

Attention-deficit/hyperactivity disorder: variation by socio-economic deprivation (2018)
Journal Article
Prasad, V., West, J., Kendrick, D., & Sayal, K. (2019). Attention-deficit/hyperactivity disorder: variation by socio-economic deprivation. Archives of Disease in Childhood, 104(8), 802-805. https://doi.org/10.1136/archdischild-2017-314470

Background: In England, there is a discrepancy between the prevalence of Attention-deficit/hyperactivity disorder (ADHD) ascertained from medical records and community surveys. There is also a lack of data on variation in recorded prevalence by depri... Read More about Attention-deficit/hyperactivity disorder: variation by socio-economic deprivation.

Systematic review and meta-analysis to assess the safety of Buproprion and Varenicline in pregnancy (2018)
Journal Article
Turner, E., Coleman, T., Jones, M., & Vaz, L. (2018). Systematic review and meta-analysis to assess the safety of Buproprion and Varenicline in pregnancy. Nicotine and Tobacco Research, 21(8), 1001–1010. https://doi.org/10.1093/ntr/nty055

Introduction: Smoking in pregnancy is a substantial public health issue, but, apart from nicotine replacement therapy (NRT), pharmacological therapies are not generally used to promote cessation. Bupropion and varenicline are effective cessation meth... Read More about Systematic review and meta-analysis to assess the safety of Buproprion and Varenicline in pregnancy.

Strategies for identifying familial hypercholesterolaemia in non-specialist clinical settings (2018)
Journal Article
Qureshi, N., Weng, S. F., Tranter, J. A., Da Silva, M. L., Kai, J., & Leonardi-Bee, J. (2018). Strategies for identifying familial hypercholesterolaemia in non-specialist clinical settings. Cochrane Database of Systematic Reviews, 3, https://doi.org/10.1002/14651858.CD012985

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: The purpose of this review is to assess the effectiveness of interventions to systematically improve identification of FH in non-specialist settings compared t... Read More about Strategies for identifying familial hypercholesterolaemia in non-specialist clinical settings.

Antidepressant use and risk of adverse outcomes in people aged 20–64 years: cohort study using a primary care database (2018)
Journal Article
Coupland, C., Hill, T., Morriss, R., Moore, M., Arthur, A., & Hippisley-Cox, J. (2018). Antidepressant use and risk of adverse outcomes in people aged 20–64 years: cohort study using a primary care database. BMC Medicine, 16(1), Article 36. https://doi.org/10.1186/s12916-018-1022-x

© 2018 The Author(s). Background: Antidepressants are one of the most commonly prescribed medications in young and middle-aged adults, but there is relatively little information on their safety across a range of adverse outcomes in this age group. Th... Read More about Antidepressant use and risk of adverse outcomes in people aged 20–64 years: cohort study using a primary care database.

Essential prescribing tips for GP Associates-in-Training (2018)
Journal Article
Gookey, G., Knox, R., Salema, N., Marsden, K., Bell, B., Bassi, M., …Avery, A. (in press). Essential prescribing tips for GP Associates-in-Training. InnovAiT, 11(2), https://doi.org/10.1177/1755738017738271

Prescribing is an essential role in general practice but it is also, at times, a high risk activity. GP Associates-in-Training (GP AiTs) have been highlighted as needing further support to reduce the risk of prescribing errors. This article highlight... Read More about Essential prescribing tips for GP Associates-in-Training.

Improving behavioral support for smoking cessation in pregnancy: what are the barriers to stopping and which behavior change techniques can influence these?: application of theoretical domains framework (2018)
Journal Article
Campbell, K., Fergie, L., Coleman-Haynes, T., Cooper, S., Lorencatto, F., Ussher, M., …Coleman, T. (2018). Improving behavioral support for smoking cessation in pregnancy: what are the barriers to stopping and which behavior change techniques can influence these?: application of theoretical domains framework. International Journal of Environmental Research and Public Health, 15(2), Article 359. https://doi.org/10.3390/ijerph15020359

Behavioral support interventions are used to help pregnant smokers stop; however, of those tested, few are proven effective. Systematic research developing effective pregnancy-specific behavior change techniques (BCTs) is ongoing. This paper reports... Read More about Improving behavioral support for smoking cessation in pregnancy: what are the barriers to stopping and which behavior change techniques can influence these?: application of theoretical domains framework.

A development study and randomised feasibility trial of a tailored intervention to improve activity and reduce falls in older adults with mild cognitive impairment and mild dementia (2018)
Journal Article
Harwood, R. H., van der Wardt, V., Goldberg, S. E., Keamey, F., Logan, P., Hood-Moore, V., …Orrell, M. (2018). A development study and randomised feasibility trial of a tailored intervention to improve activity and reduce falls in older adults with mild cognitive impairment and mild dementia. Pilot and Feasibility Studies, 4, Article 49. https://doi.org/10.1186/s40814-018-0239-y

Background: People with dementia progressively lose abilities and are prone to falling. Exercise- and activity-based interventions hold the prospect of increasing abilities, reducing falls, and slowing decline in cognition. Current falls prevention... Read More about A development study and randomised feasibility trial of a tailored intervention to improve activity and reduce falls in older adults with mild cognitive impairment and mild dementia.

A Patient Safety Toolkit for Family Practices (2018)
Journal Article
Campbell, S. M., Bell, B. G., Marsden, K., Spencer, R., Kadam, U., Perryman, K., …Avery, A. J. (2018). A Patient Safety Toolkit for Family Practices. Journal of Patient Safety, 16(3), e182-e186. https://doi.org/10.1097/pts.0000000000000471

Objectives: Major gaps remain in our understanding of primary care patient safety. We describe a toolkit for measuring patient safety in family practices. Methods: Six tools were used in 46 practices. These tools were: NHS Education for Scotlan... Read More about A Patient Safety Toolkit for Family Practices.