Skip to main content

Research Repository

Advanced Search

All Outputs (558)

Evaluation of a pharmacist-led actionable audit and feedback intervention for improving medication safety in UK primary care: An interrupted time series analysis (2020)
Journal Article
Peek, N., Gude, W. T., Keers, R. N., Williams, R., Kontopantelis, E., Jeffries, M., …Ashcroft, D. M. (2020). Evaluation of a pharmacist-led actionable audit and feedback intervention for improving medication safety in UK primary care: An interrupted time series analysis. PLoS Medicine, 17(10), Article e1003286. https://doi.org/10.1371/journal.pmed.1003286

Background: We evaluated the impact of the pharmacist-led Safety Medication dASHboard (SMASH) intervention on medication safety in primary care. Methods and findings: SMASH comprised (1) training of clinical pharmacists to deliver the intervention... Read More about Evaluation of a pharmacist-led actionable audit and feedback intervention for improving medication safety in UK primary care: An interrupted time series analysis.

Measuring physical activity levels in people with mild cognitive impairment or mild dementia (2020)
Journal Article
Van Der Wardt, V., Hancox, J. E., Burgon, C., Bajwa, R., Goldberg, S., & Harwood, R. H. (2021). Measuring physical activity levels in people with mild cognitive impairment or mild dementia. Journal of Aging and Physical Activity, 29(1), 10-16. https://doi.org/10.1123/japa.2019-0234

Measuring physical activity (PA) in people with mild cognitive impairment (MCI) or dementia can be difficult. The aim was to investigate the validity and acceptability of three different PA measurement methods. The mixed-method analysis included 49... Read More about Measuring physical activity levels in people with mild cognitive impairment or mild dementia.

Putting the voices and insights of migrants and diverse ethnic groups at the centre of our response to COVID-19 (2020)
Journal Article
Gogoi, M., Armitage, R., Brown, G., Ryan, B., Eborall, H., Qureshi, N., …Nellums, L. B. (2021). Putting the voices and insights of migrants and diverse ethnic groups at the centre of our response to COVID-19. Public Health, 197, e1-e3. https://doi.org/10.1016/j.puhe.2020.09.019

There is increasing evidence of inequities in COVID-19 infection, disease severity, and mortality across diverse ethnic groups. Despite calls to ensure ethnicity is integral to COVID-19 research, opportunities have been missed to engage with individ... Read More about Putting the voices and insights of migrants and diverse ethnic groups at the centre of our response to COVID-19.

Does acupressure help reduce nausea and vomiting in palliative care patients? A double blind randomised controlled trial (2020)
Journal Article
Perkins, P., Parkinson, A., Parker, R., Blaken, A., & Akyea, R. K. (2020). Does acupressure help reduce nausea and vomiting in palliative care patients? A double blind randomised controlled trial. BMJ Supportive and Palliative Care, 12, 58-63. https://doi.org/10.1136/bmjspcare-2020-002434

Introduction: Nausea and vomiting are common symptoms for patients with advanced cancer. While there is evidence for acupuncture point stimulation for treatment of these symptoms for patients having anticancer treatment, there is little for when they... Read More about Does acupressure help reduce nausea and vomiting in palliative care patients? A double blind randomised controlled trial.

A scoping review of psychoeducational interventions for people after transient ischemic attack and minor stroke (2020)
Journal Article
Kontou, E., Kettlewell, J., Condon, L., Thomas, S., Lee, A. R., Sprigg, N., …Shokraneh, F. (2021). A scoping review of psychoeducational interventions for people after transient ischemic attack and minor stroke. Topics in Stroke Rehabilitation, 28(5), 390-400. https://doi.org/10.1080/10749357.2020.1818473

Background: Psychoeducation can provide information and support to cope with the physical and emotional effects of a health condition. This scoping review aimed to identify the evidence regarding psychoeducational interventions for people after a Tra... Read More about A scoping review of psychoeducational interventions for people after transient ischemic attack and minor stroke.

Managing hyperlipidaemia in patients with COVID-19 and during its pandemic: An expert panel position statement from HEART UK (2020)
Journal Article
Iqbal, Z., Ho, J. H., Adam, S., France, M., Syed, A., Neely, D., …Soran, H. (2020). Managing hyperlipidaemia in patients with COVID-19 and during its pandemic: An expert panel position statement from HEART UK. Atherosclerosis, 313, 126-136. https://doi.org/10.1016/j.atherosclerosis.2020.09.008

The emergence of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which causes Coronavirus Disease 2019 (COVID-19) has resulted in a pandemic. SARS-CoV-2 is highly contagious and its severity highly variable. The fatality rate i... Read More about Managing hyperlipidaemia in patients with COVID-19 and during its pandemic: An expert panel position statement from HEART UK.

Stress and Health: A Review of Psychobiological Processes (2020)
Journal Article
O'Connor, D. B., Thayer, J. F., & Vedhara, K. (2021). Stress and Health: A Review of Psychobiological Processes. Annual Review of Psychology, 72(1), 663-688. https://doi.org/10.1146/annurev-psych-062520-122331

The cumulative science linking stress to negative health outcomes is vast. Stress can affect health directly, through autonomic and neuroendocrine responses, but also indirectly, through changes in health behaviors. In this review, we present a brief... Read More about Stress and Health: A Review of Psychobiological Processes.

Palliative outpatient parenteral antibiotic therapy: a review of 5 years of patient data (2020)
Journal Article
Hart, E., Snape, S., & Thomson, R. (2020). Palliative outpatient parenteral antibiotic therapy: a review of 5 years of patient data. JAC-Antimicrobial Resistance, 2(3), https://doi.org/10.1093/jacamr/dlaa052

Objectives: A review of patients requiring lifelong antibiotics to control, rather than cure, infection was performed [‘palliative outpatient parenteral antibiotic therapy (OPAT)’]. This was to evaluate emerging themes and complications. The aim was... Read More about Palliative outpatient parenteral antibiotic therapy: a review of 5 years of patient data.

The MRI colonic function test: Reproducibility of the Macrogol stimulus challenge (2020)
Journal Article
Wilkinson-Smith, V., Menys, A., Bradley, C., Corsetti, M., Marciani, L., Atkinson, D., …Hoad, C. (2020). The MRI colonic function test: Reproducibility of the Macrogol stimulus challenge. Neurogastroenterology and Motility, 32(11), Article e13942. https://doi.org/10.1111/nmo.13942

Background Magnetic resonance imaging (MRI) of the colonic response to a macrogol challenge drink can be used to assess the mechanisms underlying severe constipation. We measured the intra-subject reproducibility of MRI measures of colonic funct... Read More about The MRI colonic function test: Reproducibility of the Macrogol stimulus challenge.

Assessment of the Effectiveness and Cost-Effectiveness of Tailored Web- and Text-Based Smoking Cessation Support in Primary Care (iQuit in Practice II): Protocol for a Randomized Controlled Trial (2020)
Journal Article
Proctor, J., Naughton, F., Sloane, M., Hopewell, S., Brimicombe, J., Prevost, T., …Sutton, S. (2020). Assessment of the Effectiveness and Cost-Effectiveness of Tailored Web- and Text-Based Smoking Cessation Support in Primary Care (iQuit in Practice II): Protocol for a Randomized Controlled Trial. JMIR Research Protocols, 9(7), Article e17160. https://doi.org/10.2196/17160

Background: The prevalence of smoking is declining; however, it continues to be a major public health burden. In England, primary care is the health setting that provides smoking cessation support to most smokers. However, this setting has one of the... Read More about Assessment of the Effectiveness and Cost-Effectiveness of Tailored Web- and Text-Based Smoking Cessation Support in Primary Care (iQuit in Practice II): Protocol for a Randomized Controlled Trial.

GP views on the routine identification of older people living with frailty in primary care (2020)
Journal Article
Mulla, E., Orton, E., & Kendrick, D. (2020). GP views on the routine identification of older people living with frailty in primary care. British Journal of General Practice, 70(Supplement 1), https://doi.org/10.3399/bjgp20X711437

© British Journal of General Practice 2020. Background: To meet the challenges of an ageing population, the updated 2017/18 NHS GP contract requires primary care providers to use evidence-based frailty identification tools to risk-stratify all patien... Read More about GP views on the routine identification of older people living with frailty in primary care.

Factors influencing the uptake and use of nicotine replacement therapy and e-cigarettes in pregnant women who smoke: a qualitative evidence synthesis (2020)
Journal Article
Campbell, K., Coleman-Haynes, T., Bowker, K., Cooper, S. E., Connelly, S., & Coleman, T. (2020). Factors influencing the uptake and use of nicotine replacement therapy and e-cigarettes in pregnant women who smoke: a qualitative evidence synthesis. Cochrane Database of Systematic Reviews, https://doi.org/10.1002/14651858.cd013629

Background: Nicotine replacement therapy (NRT) delivers nicotine without the toxic chemicals present in tobacco smoke. It is an effective smoking cessation aid in non?pregnant smokers, but there is less evidence of effectiveness in pregnancy. Systema... Read More about Factors influencing the uptake and use of nicotine replacement therapy and e-cigarettes in pregnant women who smoke: a qualitative evidence synthesis.

The introduction of risk stratified screening into the NHS Breast Screening Programme: Views from British-Pakistani women (2020)
Journal Article
Woof, V. G., Ruane, H., French, D. P., Ulph, F., Qureshi, N., Khan, N., …Donnelly, L. S. (2020). The introduction of risk stratified screening into the NHS Breast Screening Programme: Views from British-Pakistani women. BMC Cancer, 20, Article 452. https://doi.org/10.1186/s12885-020-06959-2

Background: UK national guidelines suggest women at high-risk of breast cancer should be offered more frequent screening or preventative medications. Currently, only 1 in 6 high-risk women are identified. One route to identify more high-risk women is... Read More about The introduction of risk stratified screening into the NHS Breast Screening Programme: Views from British-Pakistani women.

Impact on survival of modelling increased surgical resection rates in patients with non-small-cell lung cancer and cardiovascular comorbidities: a VICORI study (2020)
Journal Article
Welch, C. A., Sweeting, M. J., Lambert, P. C., Rutherford, M. J., Jack, R. H., West, D., …Peake, M. (2020). Impact on survival of modelling increased surgical resection rates in patients with non-small-cell lung cancer and cardiovascular comorbidities: a VICORI study. British Journal of Cancer, 123, 471–479. https://doi.org/10.1038/s41416-020-0869-8

©2020, The Author(s). Background: The impact of cardiovascular disease (CVD) comorbidity on resection rates and survival for patients with early-stage non-small-cell lung cancer (NSCLC) is unclear. We explored if CVD comorbidity explained surgical re... Read More about Impact on survival of modelling increased surgical resection rates in patients with non-small-cell lung cancer and cardiovascular comorbidities: a VICORI study.

Nasal fentanyl alone plus buccal midazolam: an open-label, randomised, controlled feasibility study in the dying (2020)
Journal Article
Perkins, P., Parkinson, A., Akyea, R. K., & Husbands, E. (2020). Nasal fentanyl alone plus buccal midazolam: an open-label, randomised, controlled feasibility study in the dying. BMJ Supportive and Palliative Care, 10(3), 300-303. https://doi.org/10.1136/bmjspcare-2019-002029

Introduction: Many patients want to stay at home to die. They invariably become unable to take oral medication during their terminal phase. Symptoms are usually controlled by subcutaneous medications. There have been no studies on nasal fentanyl (NF)... Read More about Nasal fentanyl alone plus buccal midazolam: an open-label, randomised, controlled feasibility study in the dying.

Understanding the utilisation of a novel interactive electronic medication safety dashboard in general practice: a mixed methods study (2020)
Journal Article
Jeffries, M., Gude, W. T., Keers, R. N., Phipps, D. L., Williams, R., Kontopantelis, E., …Peek, N. (2020). Understanding the utilisation of a novel interactive electronic medication safety dashboard in general practice: a mixed methods study. BMC Medical Informatics and Decision Making, 20(1), Article 69. https://doi.org/10.1186/s12911-020-1084-5

Background: Improving medication safety is a major concern in primary care settings worldwide. The Salford Medication safety dASHboard (SMASH) intervention provided general practices in Salford (Greater Manchester, UK) with feedback on their safe pre... Read More about Understanding the utilisation of a novel interactive electronic medication safety dashboard in general practice: a mixed methods study.

Intervention Characteristics Associated With a Reduction in Fear of Falling Among Community-Dwelling Older People: A Systematic Review and Meta-analysis of Randomized Controlled Trials (2020)
Journal Article
Kruisbrink, M., Delbaere, K., Kempen, G. I., Crutzen, R., Ambergen, T., Cheung, K., …Zijlstra, G. R. (2021). Intervention Characteristics Associated With a Reduction in Fear of Falling Among Community-Dwelling Older People: A Systematic Review and Meta-analysis of Randomized Controlled Trials. Gerontologist, 61(6), Article e269–e282. https://doi.org/10.1093/geront/gnaa021

Fear of falling (FoF) is a common and serious problem for older people. Multi-component interventions usually show only moderate effects. Disentangling the effective components may help in the optimisation of interventions. Randomised controlled tria... Read More about Intervention Characteristics Associated With a Reduction in Fear of Falling Among Community-Dwelling Older People: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

Trends in incidence and prevalence of osteoarthritis in the United Kingdom: findings from the Clinical Practice Research Datalink (CPRD) (2020)
Journal Article
Swain, S., Sarmanova, A., Mallen, C., Kuo, C. F., Coupland, C., Doherty, M., & Zhang, W. (2020). Trends in incidence and prevalence of osteoarthritis in the United Kingdom: findings from the Clinical Practice Research Datalink (CPRD). Osteoarthritis and Cartilage, 28(6), 792-801. https://doi.org/10.1016/j.joca.2020.03.004

© 2020 The Authors Objective: This study aimed to explore the incidence and prevalence of OA in the UK in 2017 and their trends from 1997 to 2017 using a large nationally representative primary care database. Design: The UK Clinical Practice Research... Read More about Trends in incidence and prevalence of osteoarthritis in the United Kingdom: findings from the Clinical Practice Research Datalink (CPRD).

A randomised feasibility study assessing an intervention to keep adults physically active after falls management exercise programmes end (2020)
Journal Article
Audsley, S., Kendrick, D., Logan, P., Jones, M., & Orton, E. (2020). A randomised feasibility study assessing an intervention to keep adults physically active after falls management exercise programmes end. Pilot and Feasibility Studies, 6, Article 37. https://doi.org/10.1186/s40814-020-00570-9

Background: Physical inactivity contributes to disability and falls in older adults. Falls prevention exercise (FaME) programmes improve physical activity, physical function and reduce falling rates. Improvements in physical function reduce, and fall... Read More about A randomised feasibility study assessing an intervention to keep adults physically active after falls management exercise programmes end.

Pharmacological interventions for promoting smoking cessation during pregnancy (2020)
Journal Article
Claire, R., Chamberlain, C., Davey, M., Leonardi-Bee, J., Cooper, S. E., Berlin, I., & Coleman, T. (2020). Pharmacological interventions for promoting smoking cessation during pregnancy. Cochrane Database of Systematic Reviews, https://doi.org/10.1002/14651858.cd010078.pub3

Background: Tobacco smoking in pregnancy causes serious health problems for the developing fetus and mother. When used by non‐pregnant smokers, pharmacotherapies (nicotine replacement therapy (NRT), bupropion, and varenicline) are effective for incr... Read More about Pharmacological interventions for promoting smoking cessation during pregnancy.