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All Outputs (28)

Effectiveness of offering tailored text message, self‐help smoking cessation support to pregnant women who want information on stopping smoking: MiQuit3 randomised controlled trial (RCT) and meta‐analysis (2021)
Journal Article
Coleman, T., Clark, M., Welch, C., Whitemore, R., Leonardi‐Bee, J., Cooper, S., …Naughton, F. (2022). Effectiveness of offering tailored text message, self‐help smoking cessation support to pregnant women who want information on stopping smoking: MiQuit3 randomised controlled trial (RCT) and meta‐analysis. Addiction, 117(4), 1079-1094. https://doi.org/10.1111/add.15715

Aims: To test efficacy of “MiQuit’, a tailored, self-help, text message stop smoking programme for pregnancy, as an adjunct to usual care (UC) for smoking cessation in pregnancy. Design: Multicentre, open, two-arm, parallel-group, superiority rand... Read More about Effectiveness of offering tailored text message, self‐help smoking cessation support to pregnant women who want information on stopping smoking: MiQuit3 randomised controlled trial (RCT) and meta‐analysis.

Comparing the performance of the novel FAMCAT algorithms and established case-finding criteria for familial hypercholesterolaemia in primary care (2021)
Journal Article
Qureshi, N., Akyea, R. K., Dutton, B., Leonardi-Bee, J., Humphries, S. E., Weng, S., & Kai, J. (2021). Comparing the performance of the novel FAMCAT algorithms and established case-finding criteria for familial hypercholesterolaemia in primary care. Open Heart, 8(2), Article e001752. https://doi.org/10.1136/openhrt-2021-001752

Objective Familial hypercholesterolaemia (FH) is a common inherited disorder causing premature coronary heart disease (CHD) and death. We have developed the novel Familial Hypercholesterolaemia Case Ascertainment Tool (FAMCAT 1) case-finding algorith... Read More about Comparing the performance of the novel FAMCAT algorithms and established case-finding criteria for familial hypercholesterolaemia in primary care.

Strategies for screening for familial hypercholesterolaemia in primary care and other community settings (2021)
Journal Article
Qureshi, N., Da Silva, M. L. R., Abdul-Hamid, H., Weng, S. F., Kai, J., & Leonardi-Bee, J. (2021). Strategies for screening for familial hypercholesterolaemia in primary care and other community settings. Cochrane Database of Systematic Reviews, 2021(10), Article CD012985. https://doi.org/10.1002/14651858.cd012985.pub2

Background: Familial hypercholesterolaemia is a common inherited condition that is associated with premature cardiovascular disease. The increased cardiovascular morbidity and mortality, resulting from high levels of cholesterol since birth, can be p... Read More about Strategies for screening for familial hypercholesterolaemia in primary care and other community settings.

Effectiveness of cascade testing strategies in relatives for familial hypercholesterolemia: A systematic review and meta-analysis (2021)
Journal Article
Leonardi-Bee, J., Boateng, C., Faria, R., Eliman, K., Young, B., & Qureshi, N. (2021). Effectiveness of cascade testing strategies in relatives for familial hypercholesterolemia: A systematic review and meta-analysis. Atherosclerosis, 338, 7-14. https://doi.org/10.1016/j.atherosclerosis.2021.09.014

Background and aims: Cascade testing in relatives of index cases is the most cost-effective approach to identifying people with familial hypercholesterolemia (FH); however, it is currently unclear which strategy to contact relatives would be the most... Read More about Effectiveness of cascade testing strategies in relatives for familial hypercholesterolemia: A systematic review and meta-analysis.

Case-finding and genetic testing for familial hypercholesterolaemia in primary care (2021)
Journal Article
Qureshi, N., Akyea, R. K., Dutton, B., Leonardi-Bee, J., Humphries, S. E., Weng, S., & Kai, J. (2021). Case-finding and genetic testing for familial hypercholesterolaemia in primary care. Heart, 107(24), 1956-1961. https://doi.org/10.1136/heartjnl-2021-319742

Objective: Familial Hypercholesterolaemia (FH) is a common inherited disorder causing premature heart disease and death. We have developed novel case-finding algorithms (FAMCAT version 1 & 2) for application in primary care, to improve detection of... Read More about Case-finding and genetic testing for familial hypercholesterolaemia in primary care.

Systematic Identification of Familial Hypercholesterolaemia in Primary Care—A Systematic Review (2021)
Journal Article
Silva, L., Qureshi, N., Abdul-Hamid, H., Weng, S., Kai, J., & Leonardi-Bee, J. (2021). Systematic Identification of Familial Hypercholesterolaemia in Primary Care—A Systematic Review. Journal of Personalized Medicine, 11(4), Article 302. https://doi.org/10.3390/jpm11040302

Familial hypercholesterolaemia (FH) is a common inherited cause of premature cardiovascular disease, but the majority of patients remain undiagnosed. The aim of this systematic review was to assess the effectiveness of interventions to systematically... Read More about Systematic Identification of Familial Hypercholesterolaemia in Primary Care—A Systematic Review.

Using Trial Sequential Analysis for estimating the sample sizes of further trials: example using smoking cessation intervention (2020)
Journal Article
Claire, R., Gluud, C., Berlin, I., Coleman, T., & Leonardi-Bee, J. (2020). Using Trial Sequential Analysis for estimating the sample sizes of further trials: example using smoking cessation intervention. BMC Medical Research Methodology, 20(1), Article 284. https://doi.org/10.1186/s12874-020-01169-7

Background: Assessing benefits and harms of health interventions is resource-intensive and often requires feasibility and pilot trials followed by adequately powered randomised clinical trials. Data from feasibility and pilot trials are used to infor... Read More about Using Trial Sequential Analysis for estimating the sample sizes of further trials: example using smoking cessation intervention.

Pharmacological interventions for promoting smoking cessation during pregnancy (2020)
Journal Article
Claire, R., Chamberlain, C., Davey, M., Leonardi-Bee, J., Cooper, S. E., Berlin, I., & Coleman, T. (2020). Pharmacological interventions for promoting smoking cessation during pregnancy. Cochrane Database of Systematic Reviews, https://doi.org/10.1002/14651858.cd010078.pub3

Background: Tobacco smoking in pregnancy causes serious health problems for the developing fetus and mother. When used by non‐pregnant smokers, pharmacotherapies (nicotine replacement therapy (NRT), bupropion, and varenicline) are effective for incr... Read More about Pharmacological interventions for promoting smoking cessation during pregnancy.

Interest in and use of smoking cessation support across pregnancy and postpartum (2019)
Journal Article
Naughton, F., Reeves Vaz, L., Coleman, T., Orton, S., Bowker, K., Leonardi-Bee, J., …Ussher, M. (2020). Interest in and use of smoking cessation support across pregnancy and postpartum. Nicotine and Tobacco Research, 22(7), 1178–1186. https://doi.org/10.1093/ntr/ntz151

Background: Limited research exists on interest in and use of smoking cessation support in pregnancy and postpartum. Methods: A longitudinal cohort of pregnant smokers and recent ex-smokers were recruited in Nottinghamshire, UK (N=850). Data were... Read More about Interest in and use of smoking cessation support across pregnancy and postpartum.

Effectiveness and cost-effectiveness of a tailored text message programme (MiQuit) for smoking cessation in pregnancy: study protocol for a randomised controlled trial and meta-analysis (2019)
Journal Article
Whitemore, R., Leonardi-Bee, J., Naughton, F., Sutton, S., Cooper, S., Parrott, S., …Coleman, T. (2019). Effectiveness and cost-effectiveness of a tailored text message programme (MiQuit) for smoking cessation in pregnancy: study protocol for a randomised controlled trial and meta-analysis. Trials, 20, 1-13. https://doi.org/10.1186/s13063-019-3341-4

Background: Smoking in pregnancy is a major international public health problem. Self-help support (SHS) increases the likelihood of women stopping smoking in pregnancy and delivering this kind of support by text message could be a cost-effective way... Read More about Effectiveness and cost-effectiveness of a tailored text message programme (MiQuit) for smoking cessation in pregnancy: study protocol for a randomised controlled trial and meta-analysis.

Improving identification & management of familial hypercholesterolaemia in primary care: pre- and post-intervention study (2018)
Journal Article
Weng, S., Kai, J., Tranter, J., Leonardi-Bee, J., & Qureshi, N. (2018). Improving identification & management of familial hypercholesterolaemia in primary care: pre- and post-intervention study. Atherosclerosis, 274, 54-60. https://doi.org/10.1016/j.atherosclerosis.2018.04.037

Background and Aims: Familial hypercholesterolaemia (FH) is a major cause of premature heart disease but remains unrecognised in most patients. This study investigated if a systematic primary care-based approach to identify and manage possible FH imp... Read More about Improving identification & management of familial hypercholesterolaemia in primary care: pre- and post-intervention study.

Uptake of Tailored Text Message Smoking Cessation Support in Pregnancy When Advertised on the Internet (MiQuit): Observational Study (2018)
Journal Article
Emery, J., Coleman, T., Sutton, S., Cooper, S., Leonardi-Bee, J., Jones, M. D., & Naughton, F. (2018). Uptake of Tailored Text Message Smoking Cessation Support in Pregnancy When Advertised on the Internet (MiQuit): Observational Study. Journal of Medical Internet Research, 20(4), Article e146. https://doi.org/10.2196/jmir.8525

Background: Smoking in pregnancy is a major public health concern. Pregnant smokers are particularly difficult to reach, with low uptake of support options and few effective interventions. Text message–based self-help is a promising, low-cost interve... Read More about Uptake of Tailored Text Message Smoking Cessation Support in Pregnancy When Advertised on the Internet (MiQuit): Observational Study.

Strategies for identifying familial hypercholesterolaemia in non-specialist clinical settings (2018)
Journal Article
Qureshi, N., Weng, S. F., Tranter, J. A., Da Silva, M. L., Kai, J., & Leonardi-Bee, J. (2018). Strategies for identifying familial hypercholesterolaemia in non-specialist clinical settings. Cochrane Database of Systematic Reviews, 3, https://doi.org/10.1002/14651858.CD012985

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: The purpose of this review is to assess the effectiveness of interventions to systematically improve identification of FH in non-specialist settings compared t... Read More about Strategies for identifying familial hypercholesterolaemia in non-specialist clinical settings.

Smoking and quit attempts during pregnancy and postpartum: a longitudinal UK cohort (2017)
Journal Article
Cooper, S., Orton, S., Leonardi-Bee, J., Brotherton, E., Vanderbloemen, L., Bowker, K., …Coleman, T. (2017). Smoking and quit attempts during pregnancy and postpartum: a longitudinal UK cohort. BMJ Open, 7(11), Article e018746. https://doi.org/10.1136/bmjopen-2017-018746

Objectives Pregnancy motivates women to try stopping smoking, but little is known about timing of their quit attempts and how quitting intentions change during pregnancy and postpartum. Using longitudinal data, this study aimed to document women’s sm... Read More about Smoking and quit attempts during pregnancy and postpartum: a longitudinal UK cohort.

English stop-smoking services: one-year outcomes (2016)
Journal Article
Bauld, L., Hiscock, R., Dobbie, F., Aveyard, P., Coleman, T., Leonardi-Bee, J., …McEwan, A. (2016). English stop-smoking services: one-year outcomes. International Journal of Environmental Research and Public Health, 13(12), Article 1175. https://doi.org/10.3390/ijerph13121175

The UK is a global leader in stop-smoking support—providing free behavioral support and cessation medication via stop smoking services (SSS) without charge to smokers. This study aimed to explore the client and service characteristics associated with... Read More about English stop-smoking services: one-year outcomes.

Real-world uptake of a tailored, text message pregnancy smoking cessation programme (MiQuit) when offered online (2016)
Conference Proceeding
Emery, J., Coleman, T., Sutton, S., Cooper, S., Leonardi-Bee, J., Jones, M., & Naughton, F. (2016). Real-world uptake of a tailored, text message pregnancy smoking cessation programme (MiQuit) when offered online.

Background: Prenatal smoking is a major public health concern and uptake of NHS cessation support is low in this group. Text message-based self-help is a promising intervention for this population but little is known about its likely real-world uptak... Read More about Real-world uptake of a tailored, text message pregnancy smoking cessation programme (MiQuit) when offered online.

Multicentre, randomised controlled trial of a low-cost smoking cessation text message intervention for pregnant smokers (MiQuit) (2016)
Conference Proceeding
Naughton, F., Foster, K., Emery, J., Cooper, S., Sutton, S., Leonardi-Bee, J., …Coleman, T. (2016). Multicentre, randomised controlled trial of a low-cost smoking cessation text message intervention for pregnant smokers (MiQuit).

Background: Text message cessation programmes have potential to change smoking behaviour during pregnancy but their effectiveness is unknown. This study aimed to estimate key parameters, including effectiveness and cost-effectiveness, for delivering... Read More about Multicentre, randomised controlled trial of a low-cost smoking cessation text message intervention for pregnant smokers (MiQuit).

The association between treatment adherence to nicotine patches and smoking cessation in pregnancy (2016)
Conference Proceeding
Vaz, L. R., Aveyard, P., Cooper, S., Leonardi-Bee, J., & Coleman, T. (2016). The association between treatment adherence to nicotine patches and smoking cessation in pregnancy.

Background: In non-pregnant “quitters,” adherence to nicotine replacement therapy (NRT) increases smoking cessation. We investigated relationships between adherence to placebo or NRT patches and cessation in pregnancy, including an assessment of reve... Read More about The association between treatment adherence to nicotine patches and smoking cessation in pregnancy.

‘Opt-out’ referrals after identifying pregnant smokers using exhaled air carbon monoxide: impact on engagement with smoking cessation support (2016)
Journal Article
Campbell, K., Cooper, S., Fahy, S., Bowker, K., Leonardi-Bee, J., McEwen, A., …Coleman, T. (2017). ‘Opt-out’ referrals after identifying pregnant smokers using exhaled air carbon monoxide: impact on engagement with smoking cessation support. Tobacco Control, 26(3), 300-306. https://doi.org/10.1136/tobaccocontrol-2015-052662

Background. In the UK, free smoking cessation support is available to pregnant women; only a minority access this. ‘Opt-out’ referrals to stop smoking services (SSS) are recommended by UK guidelines. These involve identifying pregnant smokers using e... Read More about ‘Opt-out’ referrals after identifying pregnant smokers using exhaled air carbon monoxide: impact on engagement with smoking cessation support.