Skip to main content

Research Repository

Advanced Search

All Outputs (9)

Haematology (2023)
Book Chapter
Richardson, R., & Ellis, R. (2023). Haematology. In General Medicine and Surgery: Medical student revision guide (59-81). (1). Scion Publishing

Dual Adaptive Pyramid Network for Cross-Stain Histopathology Image Segmentation (2019)
Book Chapter
Hou, X., Liu, J., Xu, B., Liu, B., Chen, X., Garibaldi, J., …Qiu, G. (2019). Dual Adaptive Pyramid Network for Cross-Stain Histopathology Image Segmentation. In Medical Image Computing and Computer Assisted Intervention – MICCAI 2019: 22nd International Conference, Shenzhen, China, October 13–17, 2019, Proceedings, Part II (101-109). Springer Verlag. https://doi.org/10.1007/978-3-030-32245-8_12

Supervised semantic segmentation normally assumes the test data being in a similar data domain as the training data. However, in practice, the domain mismatch between the training and unseen data could lead to a significant performance drop. Obtainin... Read More about Dual Adaptive Pyramid Network for Cross-Stain Histopathology Image Segmentation.

Phosphorylation of PRH/HHEX by Protein Kinase CK2 regulates cell proliferation and cell migration in diverse cell types (2018)
Book Chapter
Jayaraman, P., Wadey, K., George, S., & Gaston, K. (2018). Phosphorylation of PRH/HHEX by Protein Kinase CK2 regulates cell proliferation and cell migration in diverse cell types. In F. Uchiumi (Ed.), Gene expression and regulation in mammalian cells (237--255). InTech. https://doi.org/10.5772/intechopen.72902

Disruption of the regulatory mechanisms that control cell proliferation and cell migration results in multiple disease states including cancer and leukemia. The Proline-Rich Homeodomain protein (PRH)/haematopoietically expressed homeobox protein (HHE... Read More about Phosphorylation of PRH/HHEX by Protein Kinase CK2 regulates cell proliferation and cell migration in diverse cell types.

High-throughput spheroid screens using volume, resazurin reduction and acid phosphatase activity (2017)
Book Chapter
Ivanov, D. P., Grabowska, A. M., & Garnett, M. C. (2018). High-throughput spheroid screens using volume, resazurin reduction and acid phosphatase activity. In D. F. Gilbert, & O. Friedrich (Eds.), Cell Viability Assays (43-59). Humana Press (Springer). https://doi.org/10.1007/978-1-4939-6960-9_4

© 2017, Springer Science+Business Media LLC. Mainstream adoption of physiologically relevant three-dimensional models has been slow in the last 50 years due to long, manual protocols with poor reproducibility, high price, and closed commercial platfo... Read More about High-throughput spheroid screens using volume, resazurin reduction and acid phosphatase activity.

Immunohistochemical Assessment of Leukocyte Involvement in Angiogenesis (2016)
Book Chapter
Ahmad, N. S., Martin, S. G., & Storr, S. J. (2016). Immunohistochemical Assessment of Leukocyte Involvement in Angiogenesis. In Angiogenesis Protocols (49-57). Springer New York. https://doi.org/10.1007/978-1-4939-3628-1_3

Angiogenesis is a hallmark of cancer and is important for tumor growth, development, and metastasis. Leukocytes, including neutrophils, eosinophils, basophils, lymphocytes, and monocytes, are found invading many solid tumors, and this inflammation is... Read More about Immunohistochemical Assessment of Leukocyte Involvement in Angiogenesis.

Methods for assessing the regenerative responses of neural tissue (2014)
Book Chapter
Poser, S. W., Rueger, M. A., & Androutsellis-Theotokis, A. (2014). Methods for assessing the regenerative responses of neural tissue. In B. Christ, J. Oerlecke, & P. Stock (Eds.), Animal models for stem cell therapy (293-302). Humana Press. https://doi.org/10.1007/978-1-4939-1453-1_24

In order to establish novel therapeutic paradigms and advance the field of regenerative medicine, methods for their effective implementation as well as rigorous assessment of outcomes are critical. This is especially evident and challenging in the co... Read More about Methods for assessing the regenerative responses of neural tissue.

The regulation of human papillomavirus gene expression by the E2 protein: keeping a finger in every pie (2012)
Book Chapter
Graham, S. V., & Gaston, K. L. (2012). The regulation of human papillomavirus gene expression by the E2 protein: keeping a finger in every pie. In K. Gaston (Ed.), Small DNA tumour viruses, 37--53. Caister Academic Press

The human papillomavirus (HPV) genome is around 8000 base pairs in length and it encodes only eight proteins, a limited number of protein isoforms and no known microRNAs. Despite this relative paucity of genes and gene products these viruses are high... Read More about The regulation of human papillomavirus gene expression by the E2 protein: keeping a finger in every pie.

Measuring the induction or inhibition of apoptosis by HPV proteins (2005)
Book Chapter
Kowalczyk, A. M., Roeder, G. E., Green, K., Stephens, D. J., & Gaston, K. (2005). Measuring the induction or inhibition of apoptosis by HPV proteins. In C. Davy, & J. Doorbar (Eds.), Human Papillomaviruses: methods and protocols (419 -- 432). Totowa, NJ: Humana Press. https://doi.org/10.1385/1-59259-982-6%3A419

Many viral proteins influence the cellular pathways that control cell proliferation and cell death. Some viral proteins trigger apoptotic cell death, and this may be important in host defense and viral spread. In other cases, viral proteins inhibit a... Read More about Measuring the induction or inhibition of apoptosis by HPV proteins.