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MeMa: Designing the Memory Machine (2019)
Conference Proceeding
Price, D., Jacobs, R., Darzentas, D., Perez Vallejos, E., Chadborn, N., Martindale, S., & Urquhart, L. (2019). MeMa: Designing the Memory Machine. In Companion Publication of the 2019 on Designing Interactive Systems Conference 2019 Companion, 271--276. doi:10.1145/3301019.3323882

The Memory Machine is an ambitious project that aims to develop a device to capture people's memories to create a blend of personal and factual data that builds identities, and contextualizes personal recollections. The Memory Machine has been guided... Read More

First-line ovulation induction for polycystic ovary syndrome: an individual participant data meta-analysis (2019)
Journal Article
Wang, R., Li, W., Bordewijk, E. M., Legro, R. S., Zhang, H., Wu, X., …the International Ovulation Induction IPDMA Collaboration, . (2019). First-line ovulation induction for polycystic ovary syndrome: an individual participant data meta-analysis. Human Reproduction Update, https://doi.org/10.1093/humupd/dmz029

Background: Polycystic ovary syndrome (PCOS) is the most frequent cause of anovulatory infertility. In women with PCOS, effective ovulation induction serves as an important first-line treatment for anovulatory infertility. Individual participant data... Read More

Rojiroti microfinance and child nutrition: a cluster randomised trial (2019)
Journal Article
Ojha, S., Szatkowski, L., Sinha, R., Yaron, G., Fogarty, A., Allen, S., …Smyth, A. R. (2019). Rojiroti microfinance and child nutrition: a cluster randomised trial. Archives of Disease in Childhood, https://doi.org/10.1136/archdischild-2018-316471+

Objective To determine whether Rojiroti microfinance, for poor Indian women, improves child nutrition. Design Cluster randomised trial. Setting Tolas (village communities) in Bihar State. Participants Women and children under 5 years. Int... Read More

Prehospital Transdermal Glyceryl Trinitrate for Ultra-Acute Intracerebral Hemorrhage (2019)
Journal Article
Bath, P. M., Woodhouse, L. J., Krishnan, K., Appleton, J. P., Anderson, C. S., Berge, E., …Sprigg, N. (2019). Prehospital Transdermal Glyceryl Trinitrate for Ultra-Acute Intracerebral Hemorrhage. Stroke, 50(11), https://doi.org/10.1161/STROKEAHA.119.026389

Background and Purpose— Pilot trials suggest that glyceryl trinitrate (GTN; nitroglycerin) may improve outcome when administered early after stroke onset. Methods— We undertook a multicentre, paramedic-delivered, ambulance-based, prospective ran... Read More

Testosterone therapy induces molecular programming augmenting physiological adaptations to resistance exercise in older men (2019)
Journal Article
Gharahdaghi, N., Rudrappa, S., Brook, M. S., Idris, I., Crossland, H., Hamrock, C., …Atherton, P. J. (2019). Testosterone therapy induces molecular programming augmenting physiological adaptations to resistance exercise in older men. Journal of Cachexia, Sarcopenia and Muscle, https://doi.org/10.1002/jcsm.12472

Background: The andropause is associated with declines in serum testosterone (T), loss of muscle mass (sarcopenia) and frailty. Two major interventions purported to offset sarcopenia are anabolic steroid therapies and resistance exercise training (RE... Read More

Determinants of change in Arterial Stiffness over 5 years in Early Chronic Kidney Disease (2019)
Journal Article
Mcintyre, N., Shardlow, A., Fluck, R., Mcintyre, C., & Taal, M. (2019). Determinants of change in Arterial Stiffness over 5 years in Early Chronic Kidney Disease. Nephrology Dialysis Transplantation, https://doi.org/10.1093/ndt/gfz170

Background Arterial stiffness is an established and potentially modifiable risk factor for cardiovascular disease, associated with chronic kidney disease. There have been few studies to evaluate progression of arterial stiffness over time or factors... Read More

Skin autofluorescence: an emerging biomarker in persons with kidney disease (2019)
Journal Article
Viramontes Horner, D., & Taal, M. W. (2019). Skin autofluorescence: an emerging biomarker in persons with kidney disease. Current Opinion in Nephrology and Hypertension, 28(6), 507–512. https://doi.org/10.1097/MNH.0000000000000549

Purpose of review: Skin autofluorescence (SAF) is a measure of the accumulation of advanced glycation end-products (AGEs) proposed to act as a marker of “cumulative metabolic stress”. This paper discusses mechanisms of AGE formation and reviews publi... Read More

Chronic Kidney Disease: call for an age-adapted definition (2019)
Journal Article
Delanaye, P., Jager, K. J., Bökenkamp, A., Christensson, A., Dubourg, L., Eriksen, B. O., …van den Brand, J. A. (2019). Chronic Kidney Disease: call for an age-adapted definition. Journal of the American Society of Nephrology, 30(9), https://doi.org/10.1681/ASN.2019030238

Current criteria for the diagnosis of chronic kidney disease (CKD) in adults include persistent signs of kidney damage; for example, increased urine albumin-to-creatinine ratio or a glomerular filtration rate (GFR) below the threshold of 60 mL/min pe... Read More

Effectiveness of exercise interventions for adults over 65 with moderate-to-severe dementia in community settings: a systematic review (2019)
Journal Article
Long, A., Robinson, K., Goldberg, S., & Gordon, A. L. (2019). Effectiveness of exercise interventions for adults over 65 with moderate-to-severe dementia in community settings: a systematic review. European Geriatric Medicine, https://doi.org/10.1007/s41999-019-00236-7

Purpose To conduct a systematic review of the literature to evaluate the effectiveness of exercise interventions for people with moderate-to-severe dementia in community settings. Methods Eight electronic databases (MEDLINE, Embase, CINAHL, AMED... Read More

Early-Stage Breast Cancer in Older Adults (2019)
Book Chapter
Cheung, K., Livi, L., & Brain, E. (2019). Early-Stage Breast Cancer in Older Adults. In M. Extermann (Ed.), Geriatric Oncology, 1-10. Springer. doi:10.1007/978-3-319-44870-1_33-1

Breast cancer is the most common cancer afflicting women worldwide. Its incidence peaks around 70, while mortality increases greatly after 75 years old. Given the competing risks on mortality with multimorbidities, geriatric assessment is a leitmotiv... Read More