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Two-Dimensional Population Receptive Field Mapping of Human Primary Somatosensory Cortex (2023)
Journal Article
Asghar, M., Sanchez-Panchuelo, R., Schluppeck, D., & Francis, S. (2023). Two-Dimensional Population Receptive Field Mapping of Human Primary Somatosensory Cortex. Brain Topography, 36, 816-834. https://doi.org/10.1007/s10548-023-01000-8

Functional magnetic resonance imaging can provide detailed maps of how sensory space is mapped in the human brain. Here, we use a novel 16 stimulator setup (a 4 × 4 grid) to measure two-dimensional sensory maps of between and within-digit (D2–D4) spa... Read More about Two-Dimensional Population Receptive Field Mapping of Human Primary Somatosensory Cortex.

A molecular–mechanical link in shear-induced self-assembly of a functionalized biopolymeric fluid (2023)
Journal Article
Pavlovskaya, G. E., & Meersmann, T. (2023). A molecular–mechanical link in shear-induced self-assembly of a functionalized biopolymeric fluid. Soft Matter, 19(17), 3228-3237. https://doi.org/10.1039/d2sm01381a

23Na multiple quantum filtered (MQF) rheo-NMR methods were applied to probe the molecular foundation for flow induced self-assembly in 0.5% κ-carrageenan fluid. This method is sensitive enough to utilize an endogenous sodium ion concentration of appr... Read More about A molecular–mechanical link in shear-induced self-assembly of a functionalized biopolymeric fluid.

Trajectories of cortical structures associated with stress across adolescence: a bivariate latent change score approach (2023)
Journal Article
Nweze, T., Banaschewski, T., Ajaelu, C., Okoye, C., Ezenwa, M., Whelan, R., …IMAGEN Consortium. (2023). Trajectories of cortical structures associated with stress across adolescence: a bivariate latent change score approach. Journal of Child Psychology and Psychiatry, 64(8), 1159-1175. https://doi.org/10.1111/jcpp.13793

Background: Stress exposure in childhood and adolescence has been linked to reductions in cortical structures and cognitive functioning. However, to date, most of these studies have been cross-sectional, limiting the ability to make long-term inferen... Read More about Trajectories of cortical structures associated with stress across adolescence: a bivariate latent change score approach.

A comparative, randomised MRI study of the physiological and appetitive responses to gelling (alginate) and non-gelling nasogastric tube feeds in healthy men (2023)
Journal Article
Aliyu, A. I., Nixon, A., Hoad, C., Marciani, L., Corsetti, M., Aithal, G. P., …Taylor, M. A. (2023). A comparative, randomised MRI study of the physiological and appetitive responses to gelling (alginate) and non-gelling nasogastric tube feeds in healthy men. British Journal of Nutrition, 130(8), 1316-1328. https://doi.org/10.1017/S0007114523000302

AbstractInclusion in nasogastric tube feeds (NGTF) of acid-sensitive, seaweed-derived alginate, expected to form a reversible gel in the stomach, may create a more normal intragastric state and modified gastrointestinal responses. This may ameliorate... Read More about A comparative, randomised MRI study of the physiological and appetitive responses to gelling (alginate) and non-gelling nasogastric tube feeds in healthy men.

GLP−1 Promotes Cortical and Medullary Perfusion in the Human Kidney and Maintains Renal Oxygenation During NaCl Loading (2023)
Journal Article
Haddock, B., Kristensen, K. B., Tayyab, M., Larsson, H. B. W., Lindberg, U., Vestergaard, M., …Asmar, A. (2023). GLP−1 Promotes Cortical and Medullary Perfusion in the Human Kidney and Maintains Renal Oxygenation During NaCl Loading. Journal of the American Heart Association, 12(3), Article e027712. https://doi.org/10.1161/JAHA.122.027712

Background GLP‐1 (glucagon‐like peptide‐1) receptor agonists exert beneficial long‐term effects on cardiovascular and renal outcomes. In humans, the natriuretic effect of GLP‐1 depends on GLP‐1 receptor interaction, is accompanied by suppression o... Read More about GLP−1 Promotes Cortical and Medullary Perfusion in the Human Kidney and Maintains Renal Oxygenation During NaCl Loading.

Beyond the Beta Rebound: Post-Task Responses in Oscillatory Activity follow Cessation of Working Memory Processes (2022)
Journal Article
Coleman, S. C., Seedat, Z. A., Whittaker, A. C., Lenartowicz, A., & Mullinger, K. J. (2023). Beyond the Beta Rebound: Post-Task Responses in Oscillatory Activity follow Cessation of Working Memory Processes. NeuroImage, 265, Article 119801. https://doi.org/10.1016/j.neuroimage.2022.119801

Post-task responses (PTRs) are transitionary responses occurring for several seconds between the end of a stimulus/task and a period of rest. The most well-studied of these are beta band (13 – 30 Hz) PTRs in motor networks following movement, often c... Read More about Beyond the Beta Rebound: Post-Task Responses in Oscillatory Activity follow Cessation of Working Memory Processes.

Improved Dynamic Contrast-Enhanced MRI Using Low Rank with Joint Sparsity (2022)
Journal Article
Zhang, J., Najeeb, F., Wang, X., Xu, P., Omer, H., Zheng, J., …Wang, C. (2022). Improved Dynamic Contrast-Enhanced MRI Using Low Rank with Joint Sparsity. IEEE Access, 10, 121193-121203. https://doi.org/10.1109/access.2022.3222313

This work presents a free-breathing dynamic contrast-enhanced (DCE) MRI reconstruction method called low-rank plus sparse (L+S) with joint sparsity. The proposed method improved dynamic contrast performance by integrating an additional temporal Fast... Read More about Improved Dynamic Contrast-Enhanced MRI Using Low Rank with Joint Sparsity.

Assessing General Versus Specific Liability for Externalizing Problems in Adolescence: Concurrent and Prospective Prediction of Symptoms of Conduct Disorder, ADHD, and Substance Use (2022)
Journal Article
Perkins, E. R., Joyner, K. J., Foell, J., Drislane, L. E., Brislin, S. J., Frick, P. J., …Consortium, T. I. (2022). Assessing General Versus Specific Liability for Externalizing Problems in Adolescence: Concurrent and Prospective Prediction of Symptoms of Conduct Disorder, ADHD, and Substance Use. Journal of Psychopathology and Clinical Science, 131(7), 793-807. https://doi.org/10.1037/abn0000743

This study explored the generality versus specificity of two trait-liability factors for externalizing problems — disinhibition and callousness — in the concurrent and prospective prediction of symptoms of conduct disorder, attention-deficit/hyperact... Read More about Assessing General Versus Specific Liability for Externalizing Problems in Adolescence: Concurrent and Prospective Prediction of Symptoms of Conduct Disorder, ADHD, and Substance Use.

Global and Regional Structural Differences and Prediction of Autistic Traits during Adolescence (2022)
Journal Article
Nees, F., Banaschewski, T., Bokde, A. L. W., Desrivières, S., Grigis, A., Garavan, H., …on behalf of the IMAGEN Consortium. (2022). Global and Regional Structural Differences and Prediction of Autistic Traits during Adolescence. Brain Sciences, 12(9), Article 1187. https://doi.org/10.3390/brainsci12091187

Background: Autistic traits are commonly viewed as dimensional in nature, and as continuously distributed in the general population. In this respect, the identification of predictive values of markers such as subtle autism-related alterations in brai... Read More about Global and Regional Structural Differences and Prediction of Autistic Traits during Adolescence.

Decreased renal perfusion during acute kidney injury in critical COVID-19 assessed by magnetic resonance imaging: a prospective case control study (2022)
Journal Article
Luther, T., Eckerbom, P., Cox, E., Lipcsey, M., Bülow, S., Hultström, M., …Liss, P. (2022). Decreased renal perfusion during acute kidney injury in critical COVID-19 assessed by magnetic resonance imaging: a prospective case control study. Critical Care, 26(1), 262. https://doi.org/10.1186/s13054-022-04132-8

Abstract: Background: Renal hypoperfusion has been suggested to contribute to the development of acute kidney injury (AKI) in critical COVID-19. However, limited data exist to support this. We aim to investigate the differences in renal perfusion, ox... Read More about Decreased renal perfusion during acute kidney injury in critical COVID-19 assessed by magnetic resonance imaging: a prospective case control study.

Spontaneous adverse drug reaction reporting by community pharmacists: preparedness and barriers (2022)
Journal Article
Bahlol, M., Bushell, M., Khojah, H. M., & Dewey, R. S. (2022). Spontaneous adverse drug reaction reporting by community pharmacists: preparedness and barriers. Saudi Pharmaceutical Journal, 30(7), 1052-1059. https://doi.org/10.1016/j.jsps.2022.04.006

Background: Adverse drug reactions (ADRs) are undesired, unintended responses to drugs, and are significantly underreported. Pharmacists are drug experts recognized as custodians of drug safety, who are expected to be prepared for and knowledgeable a... Read More about Spontaneous adverse drug reaction reporting by community pharmacists: preparedness and barriers.

Determining the Effects of Transcranial Direct Current Stimulation on Tinnitus, Depression, and Anxiety: A Systematic Review (2022)
Journal Article
Labree, B., Hoare, D. J., Gascoyne, L. E., Scutt, P., Del Giovane, C., & Sereda, M. (2022). Determining the Effects of Transcranial Direct Current Stimulation on Tinnitus, Depression, and Anxiety: A Systematic Review. Brain Sciences, 12(4), Article 484. https://doi.org/10.3390/brainsci12040484

Background: Tinnitus is the awareness of a sound in the absence of an external source. It affects around 10–15% of people, a significant proportion of whom also experience symptoms such as depression or anxiety that negatively affect their quality of... Read More about Determining the Effects of Transcranial Direct Current Stimulation on Tinnitus, Depression, and Anxiety: A Systematic Review.

Multiparametric magnetic resonance imaging allows non-invasive functional and structural evaluation of diabetic kidney disease (2022)
Journal Article
Makvandi, K., Hockings, P. D., Jensen, G., Unnerstall, T., Leonhardt, H., Jarl, L. V., …Baid-Agrawal, S. (2022). Multiparametric magnetic resonance imaging allows non-invasive functional and structural evaluation of diabetic kidney disease. Clinical Kidney Journal, 15(7), 1387–1402. https://doi.org/10.1093/ckj/sfac054

Background: We sought to develop a novel non-contrast multiparametric MRI (mpMRI) protocol employing several complementary techniques in a single scan session for a comprehensive functional and structural evaluation of diabetic kidney disease (DKD).... Read More about Multiparametric magnetic resonance imaging allows non-invasive functional and structural evaluation of diabetic kidney disease.

A Developmental Perspective on Facets of Impulsivity and Brain Activity Correlates From Adolescence to Adulthood (2022)
Journal Article
Kaiser, A., Holz, N. E., Banaschewski, T., Baumeister, S., Bokde, A. L. W., Desrivières, S., …Nees, F. (2022). A Developmental Perspective on Facets of Impulsivity and Brain Activity Correlates From Adolescence to Adulthood. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 7(11), 1103-1115. https://doi.org/10.1016/j.bpsc.2022.02.003

Background: On a theoretical level, impulsivity represents a multidimensional construct associated with acting without foresight, inefficient inhibitory response control, and alterations in reward processing. On an empirical level, relationships and... Read More about A Developmental Perspective on Facets of Impulsivity and Brain Activity Correlates From Adolescence to Adulthood.

Perspectives on COVID-19 prevention and treatment using herbal medicine in Vietnam: A cross-sectional study (2021)
Journal Article
Tran, V. D., Pham, D. T., Cao, T. T. N., Bahlol, M., Dewey, R. S., Le, M. H., & Nguyen, V. A. (2021). Perspectives on COVID-19 prevention and treatment using herbal medicine in Vietnam: A cross-sectional study. Annali di Igiene, Medicina Preventiva e di Comunità, 34(5), 515-531. https://doi.org/10.7416/ai.2021.2484

Introduction. The significance of herbal medicine (HM) during the COVID-19 pandemic has been confirmed. Nevertheless, limited studies have included the people perspectives on COVID-19 prevention/treatment using herbal medicine in Vietnam. Thus, this... Read More about Perspectives on COVID-19 prevention and treatment using herbal medicine in Vietnam: A cross-sectional study.

In silico evaluation and optimisation of magnetic resonance elastography of the liver (2021)
Journal Article
McGrath, D. M., Bradley, C. R., & Francis, S. T. (2021). In silico evaluation and optimisation of magnetic resonance elastography of the liver. Physics in Medicine and Biology, 66(22), Article 225005. https://doi.org/10.1088/1361-6560/ac3263

Objective. Magnetic resonance elastography (MRE) is widely adopted as a biomarker of liver fibrosis. However, in vivo MRE accuracy is difficult to assess. Approach. Finite element model (FEM) simulation was employed to evaluate liver MRE accuracy and... Read More about In silico evaluation and optimisation of magnetic resonance elastography of the liver.

Quantitative magnetic resonance imaging in perianal crohn’s disease at 1.5 and 3.0 T: A feasibility study (2021)
Journal Article
Alyami, A., Hoad, C. L., Tench, C., Bannur, U., Clarke, C., Latief, K., …Moran, G. W. (2021). Quantitative magnetic resonance imaging in perianal crohn’s disease at 1.5 and 3.0 T: A feasibility study. Diagnostics, 11(11), Article 2135. https://doi.org/10.3390/diagnostics11112135

Perianal Crohn’s Disease (pCD) is a common manifestation of Crohn’s Disease. Absence of reliable disease measures makes disease monitoring unreliable. Qualitative MRI has been increasingly used for diagnosing and monitoring pCD and has shown potentia... Read More about Quantitative magnetic resonance imaging in perianal crohn’s disease at 1.5 and 3.0 T: A feasibility study.

The role of hepatic lipid composition in obesity-related metabolic disease (2021)
Journal Article
Willis, S. A., Bawden, S., Malaikah, S., Sargeant, J. A., Stensel, D. J., Aithal, G. P., & King, J. A. (2021). The role of hepatic lipid composition in obesity-related metabolic disease. Liver International, 41(12), 2819-2835. https://doi.org/10.1111/liv.15059

Obesity is a primary antecedent to non-alcoholic fatty liver disease whose cardinal feature is excessive hepatic lipid accumulation. Although total hepatic lipid content closely associates with hepatic and systemic metabolic dysfunction, accumulating... Read More about The role of hepatic lipid composition in obesity-related metabolic disease.

Luminal fluid motion inside an in vitro dissolution model of the human ascending colon assessed using magnetic resonance imaging (2021)
Journal Article
O’Farrell, C., Hoad, C. L., Stamatopoulos, K., Marciani, L., Sulaiman, S., Simmons, M. J. H., & Batchelor, H. K. (2021). Luminal fluid motion inside an in vitro dissolution model of the human ascending colon assessed using magnetic resonance imaging. Pharmaceutics, 13(10), Article 1545. https://doi.org/10.3390/pharmaceutics13101545

Knowledge of luminal flow inside the human colon remains elusive, despite its importance for the design of new colon-targeted drug delivery systems and physiologically relevant in silico models of dissolution mechanics within the colon. This study us... Read More about Luminal fluid motion inside an in vitro dissolution model of the human ascending colon assessed using magnetic resonance imaging.

Psyllium reduces insulin-induced colonic gas production in irritable bowel syndrome: MRI and in vitro fermentation studies (2021)
Journal Article
Gunn, D., Abbas, Z., Harris, H., Major, G., Hoad, C., Gowland, P., …Spiller, R. (2022). Psyllium reduces insulin-induced colonic gas production in irritable bowel syndrome: MRI and in vitro fermentation studies. Gut, 71(5), 919-927. https://doi.org/10.1136/gutjnl-2021-324784

Objective: Health promoting dietary fibre including inulin often triggers gastrointestinal symptoms in patients with irritable bowel syndrome (IBS), limiting their intake. Our aim was to test if co-administering psyllium with inulin would reduce gas... Read More about Psyllium reduces insulin-induced colonic gas production in irritable bowel syndrome: MRI and in vitro fermentation studies.