All Outputs (7)

Developing Porous Ortho- and Pyrophosphate-Containing Glass Microspheres; Structural and Cytocompatibility Characterisation (2022)
Journal Article
Milborne, B., Murrell, L., Cardillo-Zallo, I., Titman, J., Briggs, L., Scotchford, C., …Ahmed, I. (2022). Developing Porous Ortho- and Pyrophosphate-Containing Glass Microspheres; Structural and Cytocompatibility Characterisation. Bioengineering, 9(11), Article 611. https://doi.org/10.3390/bioengineering9110611

Phosphate-based glasses (PBGs) are promising materials for bone repair and regeneration as they can be formulated to be compositionally similar to the inorganic components of bone. Alterations to the PBG formulation can be used to tailor their degrad... Read More about Developing Porous Ortho- and Pyrophosphate-Containing Glass Microspheres; Structural and Cytocompatibility Characterisation.

Tailoring Pyro- and Orthophosphate Species to Enhance Stem Cell Adhesion to Phosphate Glasses (2021)
Journal Article
De Melo, N., Murrell, L., Islam, M. T., Titman, J. J., Macri-Pellizzeri, L., Ahmed, I., & Sottile, V. (2021). Tailoring Pyro- and Orthophosphate Species to Enhance Stem Cell Adhesion to Phosphate Glasses. International Journal of Molecular Sciences, 22(2), Article 837. https://doi.org/10.3390/ijms22020837

Effect of varying the Mg with Ca content in highly porous phosphate-based glass microspheres (2020)
Journal Article
Islam, M. T., Macri-Pellizzeri, L., Hossain, K. M. Z., Sottile, V., & Ahmed, I. (2021). Effect of varying the Mg with Ca content in highly porous phosphate-based glass microspheres. Materials Science and Engineering: C, 120, Article 111668. https://doi.org/10.1016/j.msec.2020.111668

Natural ventilation is a low energy strategy used in many building types. Design approaches are mature but are dependent on variables with high uncertainty, such as the aerodynamic behaviour of purpose provided openings (PPOs), which need improved ch... Read More about Effect of varying the Mg with Ca content in highly porous phosphate-based glass microspheres.

The Use of Biomaterials in Internal Radiation Therapy (2020)
Journal Article
Milborne, B., Arafat, A., Layfield, R., Thompson, A., & Ahmed, I. (2020). The Use of Biomaterials in Internal Radiation Therapy. Recent Progress in Materials, 2(2), https://doi.org/10.21926/rpm.2002012

Radiotherapy has become one of the most prominent and effective modalities for cancer treatment and care. Ionising radiation, delivered either from external or internal sources, can be targeted to cancerous cells causing damage to DNA that can induce... Read More about The Use of Biomaterials in Internal Radiation Therapy.

Live Simultaneous Monitoring of Mineral Deposition and Lipid Accumulation in Differentiating Stem Cells (2019)
Journal Article
De Melo, N., McGinlay, S., Markus, R., Macri-Pellizzeri, L., Symonds, M. E., Ahmed, I., & Sottile, V. (2019). Live Simultaneous Monitoring of Mineral Deposition and Lipid Accumulation in Differentiating Stem Cells. Biomimetics, 4(3), 1-10. https://doi.org/10.3390/biomimetics4030048

Mesenchymal stem cells (MSCs) are progenitors for bone-forming osteoblasts and lipid-storing adipocytes, two major lineages co-existing in bone marrow. When isolated in vitro, these stem cells recapitulate osteoblast or adipocyte formation if treated... Read More about Live Simultaneous Monitoring of Mineral Deposition and Lipid Accumulation in Differentiating Stem Cells.

Porous phosphate-based glass microspheres show biocompatibility, tissue infiltration and osteogenic onset in an ovine bone defect model (2019)
Journal Article
McLaren, J. S., Macri-Pellizzeri, L., Zakir Hossain, K. M., Patel, U., Grant, D. M., Scammell, B. E., …Sottile, V. (2019). Porous phosphate-based glass microspheres show biocompatibility, tissue infiltration and osteogenic onset in an ovine bone defect model. ACS Applied Materials and Interfaces, 11(17), 15436–15446. https://doi.org/10.1021/acsami.9b04603

Phosphate-based glasses (PBG) are bioactive and fully degradable materials with tailorable degradation rates. PBGs can be produced as porous microspheres through a single-step process, using changes in their formulation and geometry to produce varyin... Read More about Porous phosphate-based glass microspheres show biocompatibility, tissue infiltration and osteogenic onset in an ovine bone defect model.

Porous calcium phosphate glass microspheres for orthobiologic applications (2018)
Journal Article
Hossain, K. M. Z., Patel, U., Kennedy, A. R., Macri-Pellizzeri, L., Sottile, V., Grant, D. M., …Ahmed, I. (2018). Porous calcium phosphate glass microspheres for orthobiologic applications. Acta Biomaterialia, 72, 396-406. https://doi.org/10.1016/j.actbio.2018.03.040

© 2018 Orthobiologics is a rapidly advancing field utilising cell-based therapies and biomaterials to enable the body to repair and regenerate musculoskeletal tissues. This paper reports on a cost-effective flame spheroidisation process for producti... Read More about Porous calcium phosphate glass microspheres for orthobiologic applications.