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Predictors of smoking cessation during pregnancy: a systematic review and meta-analysis (2017)
Journal Article
Riaz, M., Lewis, S., Naughton, F., & Ussher, M. (2018). Predictors of smoking cessation during pregnancy: a systematic review and meta-analysis. Addiction, 113(4), 610-622. https://doi.org/10.1111/add.14135

AIM: To identify factors found in the research literature to be associated with smoking cessation in pregnancy. METHODS: Electronic searches of the bibliographic databases of PubMed, EMBASE, PsycINFO, Elsevier, Scopus and ISI Web of Science were... Read More about Predictors of smoking cessation during pregnancy: a systematic review and meta-analysis.

Investigation using whole genome sequencing of a prolonged restaurant outbreak of Salmonella Typhimurium linked to the building drainage system, England, February 2015 to March 2016 (2017)
Journal Article
Mair-Jenkins, J., Borges-Stewart, R., Harbour, C., Cox-Rogers, J., Dallman, T., Ashton, P., …Puleston, R. (2017). Investigation using whole genome sequencing of a prolonged restaurant outbreak of Salmonella Typhimurium linked to the building drainage system, England, February 2015 to March 2016. Eurosurveillance, 22(49), 1-9. https://doi.org/10.2807/1560-7917.es.2017.22.49.17-00037

Following notification of a Salmonella enterica serovar Typhimurium gastroenteritis outbreak, we identified 82 cases linked to a restaurant with symptom onset from 12 February 2015 to 8 March 2016. Seventy-two cases had an isolate matching the nation... Read More about Investigation using whole genome sequencing of a prolonged restaurant outbreak of Salmonella Typhimurium linked to the building drainage system, England, February 2015 to March 2016.

Obesity and type 2 diabetes are important risk factors underlying previously undiagnosed cirrhosis in general practice: a cross-sectional study using Transient Elastography (2017)
Journal Article
Harman, D. J., Ryder, S. D., James, M. W., Wilkes, E. A., Card, T. R., Aithal, G. P., & Guha, I. N. (2018). Obesity and type 2 diabetes are important risk factors underlying previously undiagnosed cirrhosis in general practice: a cross-sectional study using Transient Elastography. Alimentary Pharmacology and Therapeutics, 47(4), 504-515. https://doi.org/10.1111/apt.14463

Background: Rising cirrhosis incidence and mortality in the United Kingdom has been attributed predominantly to excess alcohol consumption. However, metabolic risk factors such as type 2 diabetes and obesity may also be important. Aim: To screen at-... Read More about Obesity and type 2 diabetes are important risk factors underlying previously undiagnosed cirrhosis in general practice: a cross-sectional study using Transient Elastography.

Frequency of stepping down antibiotics and nebuliser treatment is lower at weekends compared to weekdays: an observational study (2017)
Journal Article
Lewis, S., Langley, T., Lacey, J., Skelly, R., Norwood, M., Sturrock, N., & Fogarty, A. W. (2017). Frequency of stepping down antibiotics and nebuliser treatment is lower at weekends compared to weekdays: an observational study. Clinical Medicine, 17(6), https://doi.org/10.7861/clinmedicine.17-6-504

We hypothesised that delays in providing non-urgent medication step-downs at weekends to medical management may be associated with increased length of stay.In a novel use of electronic prescribing data, we analysed emergency admissions from a busy ac... Read More about Frequency of stepping down antibiotics and nebuliser treatment is lower at weekends compared to weekdays: an observational study.

Cardiovascular disease, cancer and mortality among people with type 2 diabetes and alcoholic or non-alcoholic fatty liver disease hospital admission (2017)
Journal Article
Wild, S. H., Walker, J. J., Morling, J. R., McAllister, D. A., Colhoun, H., Farran, B., …Byrne, C. D. (2018). Cardiovascular disease, cancer and mortality among people with type 2 diabetes and alcoholic or non-alcoholic fatty liver disease hospital admission. Diabetes Care, 41(2), https://doi.org/10.2337/dc17-1590

OBJECTIVE: To describe associations between alcoholic fatty liver disease (ALD) or non-alcoholic fatty liver disease (NAFLD) hospital admission and cardiovascular disease (CVD), cancer, and mortality in people with T2DM. RESEARCH DESIGN AND METHODS:... Read More about Cardiovascular disease, cancer and mortality among people with type 2 diabetes and alcoholic or non-alcoholic fatty liver disease hospital admission.

Demand for CT scans increases during transition from paediatric to adult care: an observational study from 2009 to 2015 (2017)
Journal Article
Thurley, P., Crookdake, J., Norwood, M., Sturrock, N., & Fogarty, A. W. (in press). Demand for CT scans increases during transition from paediatric to adult care: an observational study from 2009 to 2015. British Journal of Radiology, https://doi.org/10.1259/bjr.20170467

OBJECTIVE: Avoiding unnecessary radiation exposure is a clinical priority in children and young adults. We aimed to explore demand for CT scans in a busy general hospital with particular interest in the period of transition from paediatric to adult m... Read More about Demand for CT scans increases during transition from paediatric to adult care: an observational study from 2009 to 2015.

An epithelial biomarker signature for idiopathic pulmonary fibrosis: an analysis from the multicentre PROFILE cohort study (2017)
Journal Article
Maher, T. M., Oballa, E., Simpson, J. K., Porte, J., Habgood, A., Fahy, W. A., …Jenkins, R. G. (in press). An epithelial biomarker signature for idiopathic pulmonary fibrosis: an analysis from the multicentre PROFILE cohort study. Lancet Respiratory Medicine, 5(12), https://doi.org/10.1016/S2213-2600%2817%2930430-7

Background: Idiopathic Pulmonary Fibrosis (IPF) is a progressive, fatal condition with a variable disease trajectory. The aim of this study was to evaluate potential biomarkers that predict outcome for people with IPF. Method: The PROFILE study is a... Read More about An epithelial biomarker signature for idiopathic pulmonary fibrosis: an analysis from the multicentre PROFILE cohort study.

Venous thromboembolism and mortality in breast cancer: cohort study with systematic review and meta-analysis (2017)
Journal Article
Khan, U. T., Walker, A. J., Baig, S., Card, T. R., Kirwan, C. C., & Grainge, M. J. (2017). Venous thromboembolism and mortality in breast cancer: cohort study with systematic review and meta-analysis. BMC Cancer, 17(747), https://doi.org/10.1186/s12885-017-3719-1

Background Breast cancer patients are at an increased risk of venous thromboembolism (VTE). However, current evidence as to whether VTE increases the risk of mortality in breast cancer patients is conflicting. We present data from a large cohort of... Read More about Venous thromboembolism and mortality in breast cancer: cohort study with systematic review and meta-analysis.

Relationship between health-related quality of life and respiratory health status among coal-based sponge iron plant workers in Barjora, India (2017)
Journal Article
Biswas, M., & Chattopadhyay, K. (in press). Relationship between health-related quality of life and respiratory health status among coal-based sponge iron plant workers in Barjora, India. Journal of Public Health, https://doi.org/10.1007/s10389-017-0861-9

Background: Many coal-based sponge iron plant workers have poor health-related quality of life in general, and specifically a poor respiratory health status. However, the relationship between their health-related quality of life and respiratory healt... Read More about Relationship between health-related quality of life and respiratory health status among coal-based sponge iron plant workers in Barjora, India.

Smoking and quit attempts during pregnancy and postpartum: a longitudinal UK cohort (2017)
Journal Article
Cooper, S., Orton, S., Leonardi-Bee, J., Brotherton, E., Vanderbloemen, L., Bowker, K., …Coleman, T. (2017). Smoking and quit attempts during pregnancy and postpartum: a longitudinal UK cohort. BMJ Open, 7(11), Article e018746. https://doi.org/10.1136/bmjopen-2017-018746

Objectives Pregnancy motivates women to try stopping smoking, but little is known about timing of their quit attempts and how quitting intentions change during pregnancy and postpartum. Using longitudinal data, this study aimed to document women’s sm... Read More about Smoking and quit attempts during pregnancy and postpartum: a longitudinal UK cohort.

Evaluation of a novel intervention providing insight into the tobacco industry to prevent the uptake of smoking in school-aged children: a mixed-methods study (2017)
Journal Article
Szatkowski, L., Taylor, J., Taylor, A., Lewis, S., Qi, W., Parrott, S., …Bains, M. (2017). Evaluation of a novel intervention providing insight into the tobacco industry to prevent the uptake of smoking in school-aged children: a mixed-methods study. BMJ Open, 7, Article e018031. https://doi.org/10.1136/bmjopen-2017-018031

Objectives: Evidence from the US Truth® campaign suggests that interventions focusing on tobacco industry practices and ethics may be effective in preventing youth smoking uptake. We developed, piloted and evaluated a school-based intervention based... Read More about Evaluation of a novel intervention providing insight into the tobacco industry to prevent the uptake of smoking in school-aged children: a mixed-methods study.

Ayurveda and lifestyle modification: research to practice (2017)
Journal Article
Chattopadhyay, K. (2017). Ayurveda and lifestyle modification: research to practice. International journal of medicine and public health, 7(3), 132-133. https://doi.org/10.5530/ijmedph.2017.3.27

The global burden of non-communicable diseases is rapidly increasing, and the essential management strategy is to follow a healthy lifestyle. Ayurveda can play a major role in this aspect, as the primary aim of Ayurveda is to prevent diseases by foll... Read More about Ayurveda and lifestyle modification: research to practice.

Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study (2017)
Journal Article
Allen, R. J., Porte, J., Braybrooke, R., Flores, C., Fingerlin, T. E., Oldham, J. M., …Jenkins, R. G. (2017). Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study. Lancet Respiratory Medicine, 5(11), https://doi.org/10.1016/S2213-2600%2817%2930387-9

Background Idiopathic pulmonary fibrosis (IPF) is a chronic progressive lung disease with high mortality, uncertain cause, and few treatment options. Studies have identified a significant genetic risk associated with the development of IPF; however,... Read More about Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study.

ECM crosslinking enhances fibroblast growth and protects against matrix proteolysis in lung fibrosis (2017)
Journal Article
Philp, C. J., Siebeke, I., Clements, D., Miller, S., Habgood, A., John, A. E., …Johnson, S. R. (2018). ECM crosslinking enhances fibroblast growth and protects against matrix proteolysis in lung fibrosis. American Journal of Respiratory Cell and Molecular Biology, 58(5), 594–603. https://doi.org/10.1165/rcmb.2016-0379OC

Idiopathic pulmonary fibrosis (IPF) is characterised by accumulation of extra cellular matrix (ECM) proteins and fibroblast proliferation. ECM cross-linking enzymes have been implicated in fibrotic diseases and we hypothesised that the ECM in IPF is... Read More about ECM crosslinking enhances fibroblast growth and protects against matrix proteolysis in lung fibrosis.

The recording and characteristics of pulmonary rehabilitation in patients with COPD using The Health Information Network (THIN) primary care database (2017)
Journal Article
Hakamy, A., McKeever, T. M., Gibson, J. E., & Bolton, C. E. (in press). The recording and characteristics of pulmonary rehabilitation in patients with COPD using The Health Information Network (THIN) primary care database. npj Primary Care Respiratory Medicine, 27(1), Article 58. https://doi.org/10.1038/s41533-017-0058-2

Pulmonary rehabilitation is recommended for patients with COPD to improve physical function, breathlessness and quality of life. Using The Health Information Network (THIN) primary care database in UK, we compared the demographic and clinical paramet... Read More about The recording and characteristics of pulmonary rehabilitation in patients with COPD using The Health Information Network (THIN) primary care database.

Can granulomatosis with polyangiitis be diagnosed earlier in primary care? A case-control study (2017)
Journal Article
Pearce, F. A., Hubbard, R., Grainge, M. J., Watts, R. A., Abhishek, A., & Lanyon, P. C. (in press). Can granulomatosis with polyangiitis be diagnosed earlier in primary care? A case-control study. QJM: An International Journal of Medicine, https://doi.org/10.1093/qjmed/hcx194

Background: People with granulomatosis with polyangiitis (GPA) commonly describe long delays before diagnosis. Aim: To study the natural history of GPA prior to diagnosis using primary care data, and determine whether clinical features could be iden... Read More about Can granulomatosis with polyangiitis be diagnosed earlier in primary care? A case-control study.

The prevalence of psychological comorbidity in people with vitiligo: a systematic review and meta-analysis (2017)
Journal Article
Osinubi, O., Grainge, M. J., Ahmed, A., Batchelor, J. M., Grindlay, D., Thompson, A., & Ratib, S. (2018). The prevalence of psychological comorbidity in people with vitiligo: a systematic review and meta-analysis. British Journal of Dermatology, 178(4), 863-878. https://doi.org/10.1111/bjd.16049

Background: Vitiligo is a chronic disorder causing skin depigmentation with global prevalence varying from 0.2 to 1.8%. UK guidelines recommend assessment of psychological state during clinical evaluation of vitiligo. However, the prevalence of psych... Read More about The prevalence of psychological comorbidity in people with vitiligo: a systematic review and meta-analysis.

Effects of seasonal and pandemic influenza on health-related quality of life, work and school absence in England: Results from the Flu Watch cohort study (2017)
Journal Article
Fragaszy, E. B., Warren-Gash, C., White, P. J., Zambon, M., Edmunds, W. J., Nguyen-Van-Tam, J. S., & Hayward, A. C. (2018). Effects of seasonal and pandemic influenza on health-related quality of life, work and school absence in England: Results from the Flu Watch cohort study. Influenza and Other Respiratory Viruses, 12(1), 171-182. https://doi.org/10.1111/irv.12506

Background: Estimates of health?related quality of life (HRQoL) and work/school absences for influenza are typically based on medically attended cases or those meeting influenza?like?illness (ILI) case definitions and thus biased towards severe disea... Read More about Effects of seasonal and pandemic influenza on health-related quality of life, work and school absence in England: Results from the Flu Watch cohort study.

Adverse maternal and birth outcomes in women admitted to hospital for hyperemesis gravidarum: A population-based cohort study (2017)
Journal Article
Fiaschi, L., Nelson-Piercy, C., Gibson, J. E., Szatkowski, L., & Tata, L. J. (in press). Adverse maternal and birth outcomes in women admitted to hospital for hyperemesis gravidarum: A population-based cohort study. Paediatric and Perinatal Epidemiology, 32(1), https://doi.org/10.1111/ppe.12416

Background: Evidence for risks of adverse maternal and birth outcomes in women with hyperemesis gravidarum (HG) is predominantly from small studies, unknown, or conflicting. Methods: A population-based cohort study using secondary health care reco... Read More about Adverse maternal and birth outcomes in women admitted to hospital for hyperemesis gravidarum: A population-based cohort study.