Skip to main content

Research Repository

Advanced Search

All Outputs (960)

Inverse association between blood pressure and pulse oximetry accuracy: an observational study in patients with suspected or confirmed COVID-19 infection (2022)
Journal Article
Crooks, C. J., West, J., Morling, J., Simmonds, M., Juurlink, I., Briggs, S., …Fogarty, A. W. (2023). Inverse association between blood pressure and pulse oximetry accuracy: an observational study in patients with suspected or confirmed COVID-19 infection. Emergency Medicine Journal, 40(3), 216-220. https://doi.org/10.1136/emermed-2022-212443

Background Pulse oximeters are a standard non-invasive tool to measure blood oxygen levels, and are used in multiple healthcare settings. It is important to understand the factors affecting their accuracy to be able to use them optimally and safely.... Read More about Inverse association between blood pressure and pulse oximetry accuracy: an observational study in patients with suspected or confirmed COVID-19 infection.

Temporal Trends in the Incidence of Hemophagocytic Lymphohistiocytosis: A Nationwide Cohort Study From England 2003–2018 (2022)
Journal Article
West, J., Stilwell, P., Liu, H., Ban, L., Bythell, M., Card, T. R., …Crooks, C. J. (2022). Temporal Trends in the Incidence of Hemophagocytic Lymphohistiocytosis: A Nationwide Cohort Study From England 2003–2018. HemaSphere, 6(11), Article e797. https://doi.org/10.1097/HS9.0000000000000797

Hemophagocytic lymphohistiocytosis (HLH) is rare, results in high mortality, and is increasingly being diagnosed. We aimed to quantify the incidence of diagnosed HLH and examine temporal trends in relation to age and associated diseases. Using nation... Read More about Temporal Trends in the Incidence of Hemophagocytic Lymphohistiocytosis: A Nationwide Cohort Study From England 2003–2018.

A clinical guideline-based management of type 2 diabetes by ayurvedic practitioners in Nepal: A feasibility cluster randomized controlled trial protocol (2022)
Journal Article
Chattopadhyay, K., Dhimal, M., Karki, S., Regmi, P., Bista, B., Biswas, T. K., …Gyanwali, P. (2022). A clinical guideline-based management of type 2 diabetes by ayurvedic practitioners in Nepal: A feasibility cluster randomized controlled trial protocol. Medicine, 101(47), Article e31452. https://doi.org/10.1097/MD.0000000000031452

Introduction: Type 2 diabetes mellitus (T2DM) is a common chronic condition with significant health and socioeconomic consequences. In Nepal, T2DM is a common disease for which people consult ayurvedic (traditional medical system) practitioners and... Read More about A clinical guideline-based management of type 2 diabetes by ayurvedic practitioners in Nepal: A feasibility cluster randomized controlled trial protocol.

The impact of the COVID-19 pandemic on smoking, vaping and smoking cessation services in the UK: A qualitative study (2022)
Journal Article
Johnston, E., Bains, M., Hunter, A., & Langley, T. (2023). The impact of the COVID-19 pandemic on smoking, vaping and smoking cessation services in the UK: A qualitative study. Nicotine & Tobacco Research, 25(2), 339-344. https://doi.org/10.1093/ntr/ntac227

BACKGROUND: Existing evidence suggests that while the coronavirus disease 2019 (COVID-19) pandemic triggered quit attempts among many smokers, it led some to smoke more and others to relapse back to smoking. These diverse effects have the potential t... Read More about The impact of the COVID-19 pandemic on smoking, vaping and smoking cessation services in the UK: A qualitative study.

Haemphagocytic Lymphohistiocytosis in an English Nationwide Cohort Confirms Increasing Incidence and Variation in Trigger Factors (2022)
Journal Article
Bishton, M., Crooks, C., Liu, H., Ban, L., Bythell, M., Card, T., …West, J. (2022). Haemphagocytic Lymphohistiocytosis in an English Nationwide Cohort Confirms Increasing Incidence and Variation in Trigger Factors. Blood, 140(Supplement 1), 2599-2600. https://doi.org/10.1182/blood-2022-158999

Background: Haemophagocytic Lymphohistiocytosis (HLH) is a rare, life-threatening hyper-inflammatory syndrome triggered by constitutive and acquired risk factors including haematological malignancy, infection, auto-immunity and rheumatological diseas... Read More about Haemphagocytic Lymphohistiocytosis in an English Nationwide Cohort Confirms Increasing Incidence and Variation in Trigger Factors.

Mosquito aquatic habitat modification and manipulation interventions to control malaria (2022)
Journal Article
Martello, E., Yogeswaran, G., Reithinger, R., & Leonardi-Bee, J. (2022). Mosquito aquatic habitat modification and manipulation interventions to control malaria. Cochrane Database of Systematic Reviews, 2022(11), Article CD008923. https://doi.org/10.1002/14651858.CD008923.pub3

Background: Larval source management (LSM) may help reduce Plasmodium parasite transmission in malaria-endemic areas. LSM approaches include habitat modification (permanently or temporarily reducing mosquito breeding aquatic habitats); habitat manipu... Read More about Mosquito aquatic habitat modification and manipulation interventions to control malaria.

The urgent need to move upstream in caring for people with rheumatic and musculoskeletal diseases (2022)
Journal Article
Bouraoui, A., Rutter, M., Williamson, L., Fisher, C., Sofat, R., & Sen, D. (2022). The urgent need to move upstream in caring for people with rheumatic and musculoskeletal diseases. Rheumatology Advances in Practice, 6(3), Article rkac092. https://doi.org/10.1093/rap/rkac092

Coronavirus disease 2019 has exposed the significant influence of social deprivation and racial disparity on health outcomes and the urgent need to move upstream for equitable, people-centred care. The upstream–downstream public health parable des... Read More about The urgent need to move upstream in caring for people with rheumatic and musculoskeletal diseases.

Prognostic factors for mortality, intensive care unit and hospital admission due to SARS-CoV-2: a systematic review and meta-analysis of cohort studies in Europe (2022)
Journal Article
Vardavas, C. I., Mathioudakis, A. G., Nikitara, K., Stamatelopoulos, K., Georgiopoulos, G., Phalkey, R., …Penttinen, P. (2022). Prognostic factors for mortality, intensive care unit and hospital admission due to SARS-CoV-2: a systematic review and meta-analysis of cohort studies in Europe. European Respiratory Review, 31(166), Article 220098. https://doi.org/10.1183/16000617.0098-2022

Background As mortality from coronavirus disease 2019 (COVID-19) is strongly age-dependent, we aimed to identify population subgroups at an elevated risk for adverse outcomes from COVID-19 using age-/gender-adjusted data from European cohort studies... Read More about Prognostic factors for mortality, intensive care unit and hospital admission due to SARS-CoV-2: a systematic review and meta-analysis of cohort studies in Europe.

Dissatisfaction of people with type 2 diabetes with the care received at a diabetes clinic in Ningbo, China: A cross‐sectional study (2022)
Journal Article
Yu, J., Li, J., Xu, M., Li, L., & Chattopadhyay, K. (2022). Dissatisfaction of people with type 2 diabetes with the care received at a diabetes clinic in Ningbo, China: A cross‐sectional study. Health Science Reports, 5(6), Article e927. https://doi.org/10.1002/hsr2.927

Aim: The study aimed to assess the dissatisfaction of people with type 2 diabetes mellitus (T2DM) with the care that they received at a diabetes outpatient clinic in Ningbo, China and to determine the associated factors. Methods: A cross-sectional... Read More about Dissatisfaction of people with type 2 diabetes with the care received at a diabetes clinic in Ningbo, China: A cross‐sectional study.

Humoral and cellular immunity in patients with rare autoimmune rheumatic diseases following SARS-CoV-2 vaccination (2022)
Journal Article
Gumber, L., Gomez, N., Hopkins, G., Tucis, D., Bartlett, L., Ayling, K., …Fairclough, L. (2023). Humoral and cellular immunity in patients with rare autoimmune rheumatic diseases following SARS-CoV-2 vaccination. Rheumatology, 62(6), 2294-2303. https://doi.org/10.1093/rheumatology/keac574

Objectives: COVID-19 vaccine responses in rare autoimmune rheumatic diseases (RAIRD) remain poorly understood, in particular there is little known about whether people develop effective T-cell responses. We conducted a prospective cohort study to eva... Read More about Humoral and cellular immunity in patients with rare autoimmune rheumatic diseases following SARS-CoV-2 vaccination.

Social support and risk of mortality in cirrhosis: A cohort study (2022)
Journal Article
Askgaard, G., Madsen, L. G., von Wowern, N., Winther-Jensen, M., Lau, C. J., Christensen, A. I., …Jepsen, P. (2023). Social support and risk of mortality in cirrhosis: A cohort study. JHEP Reports, 5(1), Article 100600. https://doi.org/10.1016/j.jhepr.2022.100600

Background & Aims The function and structure of social relationships influence mortality in individuals within the general population. We compared aspects of social relationships in patients with cirrhosis and a matched comparison c... Read More about Social support and risk of mortality in cirrhosis: A cohort study.

Long-term adverse effects and healthcare burden of rectal cancer radiotherapy: systematic review and meta-analysis (2022)
Journal Article
Morton, A. J., Rashid, A., Shim, J. S., West, J., Humes, D. J., & Grainge, M. J. (2023). Long-term adverse effects and healthcare burden of rectal cancer radiotherapy: systematic review and meta-analysis. ANZ Journal of Surgery, 93(1-2), 42-53. https://doi.org/10.1111/ans.18059

Background: As rectal cancer survival increases, more patients survive with potentially severe, long-term gastrointestinal and genitourinary complications from radiotherapy. The burden of these complications for patients and healthcare services is un... Read More about Long-term adverse effects and healthcare burden of rectal cancer radiotherapy: systematic review and meta-analysis.

Patient survey examining the experience of care of a hospital-based opt-out tobacco dependency treatment service (the CURE Project) (2022)
Journal Article
Hryhorskyj, L., Howle, F., Groom, K., Moore, R., Clegg, H., Shackley, D., …Evison, M. (2022). Patient survey examining the experience of care of a hospital-based opt-out tobacco dependency treatment service (the CURE Project). BMJ Open Respiratory Research, 9(1), Article e001334. https://doi.org/10.1136/bmjresp-2022-001334

INTRODUCTION: Treating tobacco dependency in patients admitted to hospital is a key priority in the National Health Service long-term plan. This service evaluation assessed the perception, needs and experience of care within an opt-out hospital-based... Read More about Patient survey examining the experience of care of a hospital-based opt-out tobacco dependency treatment service (the CURE Project).

International, multidisciplinary Delphi consensus recommendations on non-pharmacological interventions for fibromyalgia (2022)
Journal Article
Kundakci, B., Hall, M., Atzeni, F., Branco, J. C., Buskila, D., Clauw, D., …Taylor, A. M. (2022). International, multidisciplinary Delphi consensus recommendations on non-pharmacological interventions for fibromyalgia. Seminars in Arthritis and Rheumatism, 57, Article 152101. https://doi.org/10.1016/j.semarthrit.2022.152101

Objectives: To develop evidence-based expert recommendations for non-pharmacological treatments for pain, fatigue, sleep problems, and depression in fibromyalgia. Methods: An international, multidisciplinary Delphi exercise was conducted. Authors of... Read More about International, multidisciplinary Delphi consensus recommendations on non-pharmacological interventions for fibromyalgia.

Early Diagnosis and Lung Cancer Screening (2022)
Journal Article
Balata, H., Quaife, S. L., Craig, C., Ryan, D. . J., Bradley, P., Crosbie, P. A. J., …Evison, M. (2022). Early Diagnosis and Lung Cancer Screening. Clinical Oncology, 34(11), 708-715. https://doi.org/10.1016/j.clon.2022.08.036

Lung cancer remains the most significant cause of cancer death, accounting for about 20% of all cancer-related mortality. A significant reason for this is delayed diagnosis, either due to lack of symptoms in early-stage disease or presentation with n... Read More about Early Diagnosis and Lung Cancer Screening.

Liver blood marker testing in UK primary care: a UK wide cohort study, 2004-2016 (2022)
Journal Article
Scutt, P., Ban, L., Card, T., Crooks, C. J., Guha, N., West, J., & Morling, J. R. (2022). Liver blood marker testing in UK primary care: a UK wide cohort study, 2004-2016. BMJ Open, 12(9), e058967. https://doi.org/10.1136/bmjopen-2021-058967

OBJECTIVE: We aimed to determine (1) the temporal trends of liver enzyme testing in UK general practice and (2) how these vary among different subgroups at risk of chronic liver disease (CLD). DESIGN: Retrospective cohort study. SETTING: UK primary c... Read More about Liver blood marker testing in UK primary care: a UK wide cohort study, 2004-2016.

Perspectives of attenders and non-attenders to SARS-CoV-2 asymptomatic community testing in England: a qualitative interview study (2022)
Journal Article
Jayes, L., Bogdanovica, I., Johnston, E., Chattopadhyay, K., Morling, J. R., Devine, S., …Langley, T. (2022). Perspectives of attenders and non-attenders to SARS-CoV-2 asymptomatic community testing in England: a qualitative interview study. BMJ Open, 12(9), Article e064542. https://doi.org/10.1136/bmjopen-2022-064542

OBJECTIVES: In December 2020, Derbyshire County Council in England introduced 'walk-in' asymptomatic community COVID-19 testing sites. Our study aimed to explore people's views of the newly established COVID-19 community testing (CT) sites among thos... Read More about Perspectives of attenders and non-attenders to SARS-CoV-2 asymptomatic community testing in England: a qualitative interview study.