All Outputs (86)

Prevalence and determinants of tobacco use among young people in the Gambia (2017)
Journal Article
Jallow, I. K., Britton, J., & Langley, T. (2017). Prevalence and determinants of tobacco use among young people in the Gambia. BMJ Global Health, 2(4), Article e000482. https://doi.org/10.1136/bmjgh-2017-000482

Introduction: Tobacco consumption, and consequent morbidity and mortality, are expected to grow most markedly over coming decades in low and middle income countries (LMICs). Preventing tobacco experimentation and uptake among young people in LMICs is... Read More about Prevalence and determinants of tobacco use among young people in the Gambia.

The effect of alcohol consumption on the risk of ARDS: a systematic review and meta-analysis (2017)
Journal Article
Simou, E., Leonardi-Bee, J., & Britton, J. (in press). The effect of alcohol consumption on the risk of ARDS: a systematic review and meta-analysis. Chest, https://doi.org/10.1016/j.chest.2017.11.041

BACKGROUND: To conduct a systematic review and meta-analysis evaluating the association between alcohol consumption and the risk of ARDS in adults. METHODS: Medline, EMBASE and Web of Science were searched to identify observational studies evaluatin... Read More about The effect of alcohol consumption on the risk of ARDS: a systematic review and meta-analysis.

Cardiovascular outcomes following a respiratory tract infection among adults with non-CF bronchiectasis: a general population based study (2017)
Journal Article
Navaratnam, V., Root, A. A., Douglas, I., Smeeth, L., Hubbard, R. B., & Quint, J. K. (2018). Cardiovascular outcomes following a respiratory tract infection among adults with non-CF bronchiectasis: a general population based study. Annals of the American Thoracic Society, 15(3), https://doi.org/10.1513/AnnalsATS.201706-488OC

Rationale: Studies suggest that people with bronchiectasis are at increased risk of cardiovascular co-morbidities. Objectives: We aimed to quantify the relative risk of incident cardiovascular events following a respiratory tract infection amongs... Read More about Cardiovascular outcomes following a respiratory tract infection among adults with non-CF bronchiectasis: a general population based study.

Accurate identification of hospital admissions from care homes: development and validation of an automated algorithm (2017)
Journal Article
Housley, G., Lewis, S., Usman, A., Gordon, A. L., & Shaw, D. E. (2018). Accurate identification of hospital admissions from care homes: development and validation of an automated algorithm. Age and Ageing, 47(3), 387-391. https://doi.org/10.1093/ageing/afx182

Background: measuring the complex needs of care home residents is crucial for resource allocation. Hospital patient administration systems (PAS) may not accurately identify admissions from care homes. Objective: to develop and validate an accurate,... Read More about Accurate identification of hospital admissions from care homes: development and validation of an automated algorithm.

Direct to public peer support and e-therapy program versus information to aid self-management of depression and anxiety: protocol for a randomized controlled trial (2017)
Journal Article
Kaylor-Hughes, C., Rawsthorne, M., Coulson, N. S., Simpson, S., Simons, L., Guo, B., …Morriss, R. (in press). Direct to public peer support and e-therapy program versus information to aid self-management of depression and anxiety: protocol for a randomized controlled trial. Journal of Medical Internet Research, 6(12), Article e231. https://doi.org/10.2196/resprot.8061

Regardless of geography or income, effective help for depression and anxiety only reaches a small proportion of those who might benefit from it. The scale of the problem suggests a role for effective, safe, anonymised public health driven online serv... Read More about Direct to public peer support and e-therapy program versus information to aid self-management of depression and anxiety: protocol for a randomized controlled trial.

Long term outcomes of daily oral vs. pulsed intravenous cyclophosphamide in a non-trial setting in ANCA associated vasculitis (2017)
Journal Article
La-Crette, J., Royle, J., Lanyon, P. C., Ferraro, A., Butler, A., & Pearce, F. A. (2018). Long term outcomes of daily oral vs. pulsed intravenous cyclophosphamide in a non-trial setting in ANCA associated vasculitis. Clinical Rheumatology, 37(4), 1085–1090. https://doi.org/10.1007/s10067-017-3944-7

Objectives We aimed to compare risk of death, relapse, neutropenia and infection requiring hospital admission between unselected ANCA-associated vasculitis (AAV) patients according to whether cyclophosphamide induction was by daily oral (PO) or pulse... Read More about Long term outcomes of daily oral vs. pulsed intravenous cyclophosphamide in a non-trial setting in ANCA associated vasculitis.

Nature of events and alcohol-related content in marketing materials at a university freshers’ fair: a summative content analysis (2017)
Journal Article
Fuller, A., Fleming, K. M., Szatkowski, L., & Bains, M. (2018). Nature of events and alcohol-related content in marketing materials at a university freshers’ fair: a summative content analysis. Journal of Public Health, 40(3), e320-e327. https://doi.org/10.1093/pubmed/fdx181

Introduction:The transition to university is a potentially influential time upon students’ drinking behaviour. This study explored the nature of activities and alcohol-related content in marketing materials from student-led societies and local busine... Read More about Nature of events and alcohol-related content in marketing materials at a university freshers’ fair: a summative content analysis.

Predictors of smoking cessation during pregnancy: a systematic review and meta-analysis (2017)
Journal Article
Riaz, M., Lewis, S., Naughton, F., & Ussher, M. (2018). Predictors of smoking cessation during pregnancy: a systematic review and meta-analysis. Addiction, 113(4), 610-622. https://doi.org/10.1111/add.14135

AIM: To identify factors found in the research literature to be associated with smoking cessation in pregnancy. METHODS: Electronic searches of the bibliographic databases of PubMed, EMBASE, PsycINFO, Elsevier, Scopus and ISI Web of Science were... Read More about Predictors of smoking cessation during pregnancy: a systematic review and meta-analysis.

Investigation using whole genome sequencing of a prolonged restaurant outbreak of Salmonella Typhimurium linked to the building drainage system, England, February 2015 to March 2016 (2017)
Journal Article
Mair-Jenkins, J., Borges-Stewart, R., Harbour, C., Cox-Rogers, J., Dallman, T., Ashton, P., …Puleston, R. (2017). Investigation using whole genome sequencing of a prolonged restaurant outbreak of Salmonella Typhimurium linked to the building drainage system, England, February 2015 to March 2016. Eurosurveillance, 22(49), 1-9. https://doi.org/10.2807/1560-7917.es.2017.22.49.17-00037

Following notification of a Salmonella enterica serovar Typhimurium gastroenteritis outbreak, we identified 82 cases linked to a restaurant with symptom onset from 12 February 2015 to 8 March 2016. Seventy-two cases had an isolate matching the nation... Read More about Investigation using whole genome sequencing of a prolonged restaurant outbreak of Salmonella Typhimurium linked to the building drainage system, England, February 2015 to March 2016.

Obesity and type 2 diabetes are important risk factors underlying previously undiagnosed cirrhosis in general practice: a cross-sectional study using Transient Elastography (2017)
Journal Article
Harman, D. J., Ryder, S. D., James, M. W., Wilkes, E. A., Card, T. R., Aithal, G. P., & Guha, I. N. (2018). Obesity and type 2 diabetes are important risk factors underlying previously undiagnosed cirrhosis in general practice: a cross-sectional study using Transient Elastography. Alimentary Pharmacology and Therapeutics, 47(4), 504-515. https://doi.org/10.1111/apt.14463

Background: Rising cirrhosis incidence and mortality in the United Kingdom has been attributed predominantly to excess alcohol consumption. However, metabolic risk factors such as type 2 diabetes and obesity may also be important. Aim: To screen at-... Read More about Obesity and type 2 diabetes are important risk factors underlying previously undiagnosed cirrhosis in general practice: a cross-sectional study using Transient Elastography.

Frequency of stepping down antibiotics and nebuliser treatment is lower at weekends compared to weekdays: an observational study (2017)
Journal Article
Lewis, S., Langley, T., Lacey, J., Skelly, R., Norwood, M., Sturrock, N., & Fogarty, A. W. (2017). Frequency of stepping down antibiotics and nebuliser treatment is lower at weekends compared to weekdays: an observational study. Clinical Medicine, 17(6), https://doi.org/10.7861/clinmedicine.17-6-504

We hypothesised that delays in providing non-urgent medication step-downs at weekends to medical management may be associated with increased length of stay.In a novel use of electronic prescribing data, we analysed emergency admissions from a busy ac... Read More about Frequency of stepping down antibiotics and nebuliser treatment is lower at weekends compared to weekdays: an observational study.

Cardiovascular disease, cancer and mortality among people with type 2 diabetes and alcoholic or non-alcoholic fatty liver disease hospital admission (2017)
Journal Article
Wild, S. H., Walker, J. J., Morling, J. R., McAllister, D. A., Colhoun, H., Farran, B., …Byrne, C. D. (2018). Cardiovascular disease, cancer and mortality among people with type 2 diabetes and alcoholic or non-alcoholic fatty liver disease hospital admission. Diabetes Care, 41(2), https://doi.org/10.2337/dc17-1590

OBJECTIVE: To describe associations between alcoholic fatty liver disease (ALD) or non-alcoholic fatty liver disease (NAFLD) hospital admission and cardiovascular disease (CVD), cancer, and mortality in people with T2DM. RESEARCH DESIGN AND METHODS:... Read More about Cardiovascular disease, cancer and mortality among people with type 2 diabetes and alcoholic or non-alcoholic fatty liver disease hospital admission.

Demand for CT scans increases during transition from paediatric to adult care: an observational study from 2009 to 2015 (2017)
Journal Article
Thurley, P., Crookdake, J., Norwood, M., Sturrock, N., & Fogarty, A. W. (in press). Demand for CT scans increases during transition from paediatric to adult care: an observational study from 2009 to 2015. British Journal of Radiology, https://doi.org/10.1259/bjr.20170467

OBJECTIVE: Avoiding unnecessary radiation exposure is a clinical priority in children and young adults. We aimed to explore demand for CT scans in a busy general hospital with particular interest in the period of transition from paediatric to adult m... Read More about Demand for CT scans increases during transition from paediatric to adult care: an observational study from 2009 to 2015.

An epithelial biomarker signature for idiopathic pulmonary fibrosis: an analysis from the multicentre PROFILE cohort study (2017)
Journal Article
Maher, T. M., Oballa, E., Simpson, J. K., Porte, J., Habgood, A., Fahy, W. A., …Jenkins, R. G. (in press). An epithelial biomarker signature for idiopathic pulmonary fibrosis: an analysis from the multicentre PROFILE cohort study. Lancet Respiratory Medicine, 5(12), https://doi.org/10.1016/S2213-2600%2817%2930430-7

Background: Idiopathic Pulmonary Fibrosis (IPF) is a progressive, fatal condition with a variable disease trajectory. The aim of this study was to evaluate potential biomarkers that predict outcome for people with IPF. Method: The PROFILE study is a... Read More about An epithelial biomarker signature for idiopathic pulmonary fibrosis: an analysis from the multicentre PROFILE cohort study.

Venous thromboembolism and mortality in breast cancer: cohort study with systematic review and meta-analysis (2017)
Journal Article
Khan, U. T., Walker, A. J., Baig, S., Card, T. R., Kirwan, C. C., & Grainge, M. J. (2017). Venous thromboembolism and mortality in breast cancer: cohort study with systematic review and meta-analysis. BMC Cancer, 17(747), https://doi.org/10.1186/s12885-017-3719-1

Background Breast cancer patients are at an increased risk of venous thromboembolism (VTE). However, current evidence as to whether VTE increases the risk of mortality in breast cancer patients is conflicting. We present data from a large cohort of... Read More about Venous thromboembolism and mortality in breast cancer: cohort study with systematic review and meta-analysis.

Relationship between health-related quality of life and respiratory health status among coal-based sponge iron plant workers in Barjora, India (2017)
Journal Article
Biswas, M., & Chattopadhyay, K. (in press). Relationship between health-related quality of life and respiratory health status among coal-based sponge iron plant workers in Barjora, India. Journal of Public Health, https://doi.org/10.1007/s10389-017-0861-9

Background: Many coal-based sponge iron plant workers have poor health-related quality of life in general, and specifically a poor respiratory health status. However, the relationship between their health-related quality of life and respiratory healt... Read More about Relationship between health-related quality of life and respiratory health status among coal-based sponge iron plant workers in Barjora, India.

Evaluation of a novel intervention providing insight into the tobacco industry to prevent the uptake of smoking in school-aged children: a mixed-methods study (2017)
Journal Article
Szatkowski, L., Taylor, J., Taylor, A., Lewis, S., Qi, W., Parrott, S., …Bains, M. (2017). Evaluation of a novel intervention providing insight into the tobacco industry to prevent the uptake of smoking in school-aged children: a mixed-methods study. BMJ Open, 7, Article e018031. https://doi.org/10.1136/bmjopen-2017-018031

Objectives: Evidence from the US Truth® campaign suggests that interventions focusing on tobacco industry practices and ethics may be effective in preventing youth smoking uptake. We developed, piloted and evaluated a school-based intervention based... Read More about Evaluation of a novel intervention providing insight into the tobacco industry to prevent the uptake of smoking in school-aged children: a mixed-methods study.

Smoking and quit attempts during pregnancy and postpartum: a longitudinal UK cohort (2017)
Journal Article
Cooper, S., Orton, S., Leonardi-Bee, J., Brotherton, E., Vanderbloemen, L., Bowker, K., …Coleman, T. (2017). Smoking and quit attempts during pregnancy and postpartum: a longitudinal UK cohort. BMJ Open, 7(11), Article e018746. https://doi.org/10.1136/bmjopen-2017-018746

Objectives Pregnancy motivates women to try stopping smoking, but little is known about timing of their quit attempts and how quitting intentions change during pregnancy and postpartum. Using longitudinal data, this study aimed to document women’s sm... Read More about Smoking and quit attempts during pregnancy and postpartum: a longitudinal UK cohort.

Ayurveda and lifestyle modification: research to practice (2017)
Journal Article
Chattopadhyay, K. (2017). Ayurveda and lifestyle modification: research to practice. International journal of medicine and public health, 7(3), 132-133. https://doi.org/10.5530/ijmedph.2017.3.27

The global burden of non-communicable diseases is rapidly increasing, and the essential management strategy is to follow a healthy lifestyle. Ayurveda can play a major role in this aspect, as the primary aim of Ayurveda is to prevent diseases by foll... Read More about Ayurveda and lifestyle modification: research to practice.

ECM crosslinking enhances fibroblast growth and protects against matrix proteolysis in lung fibrosis (2017)
Journal Article
Philp, C. J., Siebeke, I., Clements, D., Miller, S., Habgood, A., John, A. E., …Johnson, S. R. (2018). ECM crosslinking enhances fibroblast growth and protects against matrix proteolysis in lung fibrosis. American Journal of Respiratory Cell and Molecular Biology, 58(5), 594–603. https://doi.org/10.1165/rcmb.2016-0379OC

Idiopathic pulmonary fibrosis (IPF) is characterised by accumulation of extra cellular matrix (ECM) proteins and fibroblast proliferation. ECM cross-linking enzymes have been implicated in fibrotic diseases and we hypothesised that the ECM in IPF is... Read More about ECM crosslinking enhances fibroblast growth and protects against matrix proteolysis in lung fibrosis.