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Protocol for a multi-centre randomised controlled stand-alone feasibility trial to assess potential effectiveness and cost-effectiveness of digital hearing aids in patients with tinnitus and hearing loss (the HUSH trial) (2020)
Journal Article
Haines, R., White, J., Meakin, G., Tan, W., Hepburn, T., Leighton, P., …Sereda, M. (2020). Protocol for a multi-centre randomised controlled stand-alone feasibility trial to assess potential effectiveness and cost-effectiveness of digital hearing aids in patients with tinnitus and hearing loss (the HUSH trial). Pilot and Feasibility Studies, 6, Article 41. https://doi.org/10.1186/s40814-020-00582-5

Background: The most common management strategy for tinnitus provided in UK audiology clinics is education and advice. This may also be combined with some form of sound therapy (e.g. digital hearing aids). While education and advice is generally prov... Read More about Protocol for a multi-centre randomised controlled stand-alone feasibility trial to assess potential effectiveness and cost-effectiveness of digital hearing aids in patients with tinnitus and hearing loss (the HUSH trial).

An evaluation of paediatric tinnitus services in UK National Health Service audiology departments (2020)
Journal Article
Smith, H., Fackrell, K., Kennedy, V., Barry, J. G., Broomhead, E., & Hoare, D. J. (2020). An evaluation of paediatric tinnitus services in UK National Health Service audiology departments. BMC Health Services Research, 20(1), Article 214. https://doi.org/10.1186/s12913-020-5040-y

© 2020 The Author(s). Background: Whilst evidence indicates many children experience troublesome tinnitus, specialist services for children are far less established than those available for adults. To date, there is limited understanding of how paedi... Read More about An evaluation of paediatric tinnitus services in UK National Health Service audiology departments.

Readability assessment of self-report hyperacusis questionnaires (2020)
Journal Article
Margol-Gromada, M., Sereda, M., & Baguley, D. M. (2020). Readability assessment of self-report hyperacusis questionnaires. International Journal of Audiology, 59(7), 506-512. https://doi.org/10.1080/14992027.2020.1723033

Objective: To assess the overall readability of five currently available hyperacusis questionnaires and to assess the variability of single items within each questionnaire. Design: Comparative study of self-report hyperacusis questionnaires: (1) Gerä... Read More about Readability assessment of self-report hyperacusis questionnaires.

A process for prioritising systematic reviews in tinnitus (2020)
Journal Article
Sereda, M., McFerran, D., Axon, E., Baguley, D. M., Hall, D. A., Potgieter, I., …Hoare, D. J. (2020). A process for prioritising systematic reviews in tinnitus. International Journal of Audiology, 59(8), 640-646. https://doi.org/10.1080/14992027.2020.1733677

© 2020 British Society of Audiology, International Society of Audiology, and Nordic Audiological Society. Objective: To develop an innovative prioritisation process to identify topics for new or updated systematic reviews of tinnitus research. Design... Read More about A process for prioritising systematic reviews in tinnitus.

Core Rehabilitation Outcome Set for Single Sided Deafness (CROSSSD) study: protocol for an international consensus on outcome measures for single sided deafness interventions using a modified Delphi survey (2020)
Journal Article
Katiri, R., Hall, D. A., Buggy, N., Hogan, N., Horobin, A., van de Heyning, P., …Kitterick, P. T. (2020). Core Rehabilitation Outcome Set for Single Sided Deafness (CROSSSD) study: protocol for an international consensus on outcome measures for single sided deafness interventions using a modified Delphi survey. Trials, 21(1), Article 238. https://doi.org/10.1186/s13063-020-4094-9

Background Single-sided deafness (SSD) describes the presence of a unilateral severe to profound sensorineural hearing loss. SSD disrupts spatial hearing and understanding speech in background noise. It has functional, psychological and social con... Read More about Core Rehabilitation Outcome Set for Single Sided Deafness (CROSSSD) study: protocol for an international consensus on outcome measures for single sided deafness interventions using a modified Delphi survey.

Neuropsychological outcomes of children with Optic Pathway Glioma (2020)
Journal Article
Papini, C., Dineen, R. A., Walker, D. A., Thomas, S., & Pitchford, N. J. (2020). Neuropsychological outcomes of children with Optic Pathway Glioma. Scientific Reports, 10(1), Article 3344. https://doi.org/10.1038/s41598-020-59896-2

Optic Pathway Glioma (OPG) is a relatively common brain tumour in childhood; however, there is scarce understanding of neuropsychological sequelae in these survivors. In this study, 12 children with diagnosis of OPG before 6 years of age received a c... Read More about Neuropsychological outcomes of children with Optic Pathway Glioma.

Calcium buffers and L-type calcium channels as modulators of cardiac subcellular alternans (2020)
Journal Article
Lai, Y. M., Coombes, S., & Thul, R. (2020). Calcium buffers and L-type calcium channels as modulators of cardiac subcellular alternans. Communications in Nonlinear Science and Numerical Simulation, 85, Article 105181. https://doi.org/10.1016/j.cnsns.2020.105181

In cardiac myocytes, calcium cycling links the dynamics of the membrane potential to the activation of the contractile filaments. Perturbations of the calcium signalling toolkit have been demonstrated to disrupt this connection and lead to numerous p... Read More about Calcium buffers and L-type calcium channels as modulators of cardiac subcellular alternans.

Graph Theoretic Analysis of Brain Connectomics in Multiple Sclerosis: Reliability and Relationship to Cognition (2020)
Journal Article
Welton, T., Constantinescu, C. S., Auer, D. P., & Dineen, R. A. (2020). Graph Theoretic Analysis of Brain Connectomics in Multiple Sclerosis: Reliability and Relationship to Cognition. Brain Connectivity, 10(2), 95-104. https://doi.org/10.1089/brain.2019.0717

Research suggests that disruption of brain networks might explain cognitive deficits in multiple sclerosis (MS). The reliability and effectiveness of graph-theoretic network metrics as measures of cognitive performance were tested in 37 people with M... Read More about Graph Theoretic Analysis of Brain Connectomics in Multiple Sclerosis: Reliability and Relationship to Cognition.

Face and content validity analysis of the Speech, Spatial and Qualities of Hearing Scale for Parents (SSQ-P) when used in a clinical service without interviews or week-long observation periods (2020)
Journal Article
Killan, C. F., Baxter, P. D., & Killan, E. C. (2020). Face and content validity analysis of the Speech, Spatial and Qualities of Hearing Scale for Parents (SSQ-P) when used in a clinical service without interviews or week-long observation periods. International Journal of Pediatric Otorhinolaryngology, 133, Article 109964. https://doi.org/10.1016/j.ijporl.2020.109964

Objectives To assess the face and content validity of the Speech, Spatial and Qualities of Hearing Scale for Parents (SSQ-P) when used in a clinical setting without the recommended interviews and observation periods. Methods SSQ-P responses comp... Read More about Face and content validity analysis of the Speech, Spatial and Qualities of Hearing Scale for Parents (SSQ-P) when used in a clinical service without interviews or week-long observation periods.

Does the magnetization transfer effect bias chemical exchange saturation transfer effects? Quantifying chemical exchange saturation transfer in the presence of magnetization transfer (2020)
Journal Article
Smith, A. K., Ray, K. J., Larkin, J. R., Craig, M., Smith, S. A., & Chappell, M. A. (2020). Does the magnetization transfer effect bias chemical exchange saturation transfer effects? Quantifying chemical exchange saturation transfer in the presence of magnetization transfer. Magnetic Resonance in Medicine, 84(3), 1359-1375. https://doi.org/10.1002/mrm.28212

Brain perfusion patterns are altered in chronic knee pain: a spatial covariance analysis of arterial spin labelling MRI (2020)
Journal Article
Iwabuchi, S. J., Xing, Y., Cottam, W. J., Drabek, M. M., Tadjibaev, A., Fernandes, G. S., …Auer, D. P. (2020). Brain perfusion patterns are altered in chronic knee pain: a spatial covariance analysis of arterial spin labelling MRI. PAIN, 161(6), 1255-1263. https://doi.org/10.1097/j.pain.0000000000001829

Chronic musculoskeletal pain is a common problem globally. Current evidence suggests that maladapted central pain pathways are associated with pain chronicity, for example, in postoperative pain after knee replacement. Other factors such as low mood,... Read More about Brain perfusion patterns are altered in chronic knee pain: a spatial covariance analysis of arterial spin labelling MRI.

Intracerebral implantation of human neural stem cells and motor recovery after stroke: multicentre prospective single-arm study (PISCES-2) (2020)
Journal Article
Muir, K. W., Bulters, D., Willmot, M., Sprigg, N., Dixit, A., Ward, N., …Sinden, J. (2020). Intracerebral implantation of human neural stem cells and motor recovery after stroke: multicentre prospective single-arm study (PISCES-2). Journal of Neurology, Neurosurgery and Psychiatry, 91(4), 396-401. https://doi.org/10.1136/jnnp-2019-322515

Background Human neural stem cell implantation may offer improved recovery from stroke. We investigated the feasibility of intracerebral implantation of the allogeneic human neural stem cell line CTX0E03 in the subacute—chronic recovery phase of... Read More about Intracerebral implantation of human neural stem cells and motor recovery after stroke: multicentre prospective single-arm study (PISCES-2).

Hypercapnia augments resistive exercise?induced elevations in intraocular pressure in older individuals (2020)
Journal Article
Mekjavic, I. B., Amoaku, W., Mlinar, T., & Mekjavic, P. J. (2020). Hypercapnia augments resistive exercise?induced elevations in intraocular pressure in older individuals. Experimental Physiology, 105(4), 641-651. https://doi.org/10.1113/ep088236

The present study assessed the effect of 6° head down (establishing the cephalad displacement noted in astronauts in microgravity) prone (simulating the effect on the eye) tilt during rest and exercise (simulating exercise performed by astronauts to... Read More about Hypercapnia augments resistive exercise?induced elevations in intraocular pressure in older individuals.

Age, sex, race and ethnicity representativeness of randomised controlled trials in peri?operative medicine (2020)
Journal Article
Lindsay, W. A., Murphy, M. M., Almghairbi, D. S., & Moppett, I. K. (2020). Age, sex, race and ethnicity representativeness of randomised controlled trials in peri?operative medicine. Anaesthesia, 75(6), 809-815. https://doi.org/10.1111/anae.14967

The applicability of the results of any clinical trial will depend to a large extent on whether the study population is representative of the population seen in clinical practice. The growing older surgical population presents challenges for peri-ope... Read More about Age, sex, race and ethnicity representativeness of randomised controlled trials in peri?operative medicine.

Effect of oxygen fraction on airway rescue: a computational modelling study (2020)
Journal Article
Laviola, M., Niklas, C., Das, A., Bates, D. G., & Hardman, J. G. (2020). Effect of oxygen fraction on airway rescue: a computational modelling study. British Journal of Anaesthesia, 125(1), e69-e74. https://doi.org/10.1016/j.bja.2020.01.004

© 2020 British Journal of Anaesthesia Background: During induction of general anaesthesia, patients frequently experience apnoea, which can lead to dangerous hypoxaemia. An obstructed upper airway can impede attempts to provide ventilation. Although... Read More about Effect of oxygen fraction on airway rescue: a computational modelling study.

Robust Data-Driven Auditory Profiling Towards Precision Audiology (2020)
Journal Article
Sanchez-Lopez, R., Fereczkowski, M., Neher, T., Santurette, S., & Dau, T. (2020). Robust Data-Driven Auditory Profiling Towards Precision Audiology. Trends in Hearing, 24, https://doi.org/10.1177/2331216520973539

The sources and consequences of a sensorineural hearing loss are diverse. While several approaches have aimed at disentangling the physiological and perceptual consequences of different etiologies, hearing deficit characterization and rehabilitation... Read More about Robust Data-Driven Auditory Profiling Towards Precision Audiology.