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Age, sex, race and ethnicity representativeness of randomised controlled trials in peri-operative medicine (2020)
Journal Article
Lindsay, W. A., Murphy, M. M., Almghairbi, D. S., & Moppett, I. K. (2020). Age, sex, race and ethnicity representativeness of randomised controlled trials in peri-operative medicine. Anaesthesia, https://doi.org/10.1111/anae.14967

The applicability of the results of any clinical trial will depend to a large extent on whether the study population is representative of the population seen in clinical practice. The growing older surgical population presents challenges for peri-ope... Read More about Age, sex, race and ethnicity representativeness of randomised controlled trials in peri-operative medicine.

Hookworm treatment for relapsing multiple sclerosis - a randomised double-blinded placebo controlled trial (2020)
Journal Article
Tanasescu, R., Tench, C. R., Constantinescu, C. S., Telford, G., Singh, S., Frakich, N., …Pritchard, D. I. (in press). Hookworm treatment for relapsing multiple sclerosis - a randomised double-blinded placebo controlled trial. JAMA Neurology,

Importance: Studies suggest gut worms induce immune responses that can protect against multiple sclerosis (MS). There are no controlled treatment trials with helminth in MS. Objective: To determine whether hookworm treatment has effects on MRI acti... Read More about Hookworm treatment for relapsing multiple sclerosis - a randomised double-blinded placebo controlled trial.

Differential Expression of HERV-W in Peripheral blood in Multiple Sclerosis and Healthy Patients in Two Different Ethnic Groups (2020)
Journal Article
Tarlinton, R. E., Wang, B., Morandi, E., Gran, B., Khaibullin, T., Martynova, E., …Khaiboullina, S. (2020). Differential Expression of HERV-W in Peripheral blood in Multiple Sclerosis and Healthy Patients in Two Different Ethnic Groups. Frontiers in Immunology, 10, https://doi.org/10.3389/fphar.2019.01645

Overexpression of the Human endogenous retrovirus W (HERV-W) group of inherited retroviruses has been consistently linked with Multiple Sclerosis (MS). However most of the studies on this link have focused on European genetic groups with a very high... Read More about Differential Expression of HERV-W in Peripheral blood in Multiple Sclerosis and Healthy Patients in Two Different Ethnic Groups.

Readability Assessment of Self-Report Hyperacusis Questionnaires (2020)
Journal Article
Margol-Gromada, M., Sereda, M., & Baguley, D. M. (in press). Readability Assessment of Self-Report Hyperacusis Questionnaires. International Journal of Audiology,

Objective: To assess the overall readability of five currently available hyperacusis questionnaires and to assess the variability of single items within each questionnaire. Design: Comparative study of self-report hyperacusis questionnaires: (1) Gerä... Read More about Readability Assessment of Self-Report Hyperacusis Questionnaires.

Incidence and predictors of early seizures in intracerebral haemorrhage and the effect of tranexamic acid (2020)
Journal Article
Woodhouse, L. J., Mistri, A. K., Bath, P. M., Law, Z. K., England, T. J., Mistri, A. K., …TICH-2 investigators, . (2020). Incidence and predictors of early seizures in intracerebral haemorrhage and the effect of tranexamic acid. European Stroke Journal, https://doi.org/10.1177/2396987320901391

Introduction Seizures are common after intracerebral haemorrhage. Tranexamic acid increases the risk of seizures in non-intracerebral haemorrhage population but its effect on post-intracerebral haemorrhage seizures is unknown. We explored the risk f... Read More about Incidence and predictors of early seizures in intracerebral haemorrhage and the effect of tranexamic acid.

Transdermal delivery of glyceryl trinitrate: clinical applications in acute stroke (2020)
Journal Article
Bath, P. M., Appleton, J. P., Appleton, J. P., Krishnan, K., & Bath, P. M. (2020). Transdermal delivery of glyceryl trinitrate: clinical applications in acute stroke. Expert Opinion on Drug Delivery, https://doi.org/10.1080/17425247.2020.1716727

© 2020, © 2020 Informa UK Limited, trading as Taylor & Francis Group. Introduction: Glyceryl trinitrate (GTN), a nitric oxide donor, is a candidate treatment for the management of acute stroke with hemodynamic and potential reperfusion and neuropro... Read More about Transdermal delivery of glyceryl trinitrate: clinical applications in acute stroke.

Tinnitus healthcare: a survey revealing extensive variation in opinion and practices across Europe (2020)
Journal Article
Cima, R. F., Kikidis, D., Mazurek, B., Haider, H., Cederroth, C. R., Norena, A., …Hoare, D. J. (2020). Tinnitus healthcare: a survey revealing extensive variation in opinion and practices across Europe. BMJ Open, 10(1), https://doi.org/10.1136/bmjopen-2019-029346

Tinnitus remains a scientific and clinical problem whereby, in spite of increasing knowledge on effective treatment and management for tinnitus, very little impact on clinical practice has been observed. There is evidence that prolonged, obscure and... Read More about Tinnitus healthcare: a survey revealing extensive variation in opinion and practices across Europe.

Endothelial progenitor cells, potential biomarkers for diagnosis and prognosis of ischemic stroke: protocol for an observational case-control study (2020)
Journal Article
Bayraktutan, U. (2020). Endothelial progenitor cells, potential biomarkers for diagnosis and prognosis of ischemic stroke: protocol for an observational case-control study. Academic Medicine, 15(7), 1300-1307. https://doi.org/10.4103/1673-5374.269028

Ischemic stroke is a devastating, life altering event which can severely reduce patient quality of life. Despite years of research there have been minimal therapeutic advances. Endothelial progenitor cells (EPCs), stem cells involved in both vasculog... Read More about Endothelial progenitor cells, potential biomarkers for diagnosis and prognosis of ischemic stroke: protocol for an observational case-control study.

Image-guided neural activity manipulation with a paramagnetic drug (2020)
Journal Article
Bricault, S., Barandov, A., Harvey, P., DeTienne, E., Hai, A., & Jasanoff, A. (2020). Image-guided neural activity manipulation with a paramagnetic drug. Nature Communications, 11(1), https://doi.org/10.1038/s41467-019-13933-5

© 2020, The Author(s). Targeted manipulations of neural activity are essential approaches in neuroscience and neurology, but monitoring such procedures in the living brain remains a significant challenge. Here we introduce a paramagnetic analog of th... Read More about Image-guided neural activity manipulation with a paramagnetic drug.

Behavioural activation treatment for depression in individuals with neurological conditions: a systematic review (2019)
Journal Article
Oates, L. L., Moghaddam, N., Evangelou, N., & das Nair, R. (2019). Behavioural activation treatment for depression in individuals with neurological conditions: a systematic review. Clinical Rehabilitation, https://doi.org/10.1177/0269215519896404

© The Author(s) 2019. Objective: To evaluate the effectiveness of behavioural activation interventions for people with neurological conditions with comorbid depression, and explore content and adaptations. Data sources: PsycINFO, MEDLINE, CINAHL, AME... Read More about Behavioural activation treatment for depression in individuals with neurological conditions: a systematic review.

Looking beyond the audiogram in ototoxicity associated with platinum-based chemotherapy (2019)
Journal Article
Baguley, D. M., & Prayuenyong, P. (2019). Looking beyond the audiogram in ototoxicity associated with platinum-based chemotherapy. Cancer Chemotherapy and Pharmacology, https://doi.org/10.1007/s00280-019-04012-z

© 2019, The Author(s). Introduction: Ototoxicity associated with platinum-based chemotherapy is highly prevalent and can cause detrimental consequences among cancer survivors. Discussion: In this article, we highlight important aspects of the evaluat... Read More about Looking beyond the audiogram in ototoxicity associated with platinum-based chemotherapy.