Skip to main content

Research Repository

Advanced Search

All Outputs (816)

Prescribing opioid analgesics for chronic non-malignant pain in general practice - a survey of attitudes and practice (2015)
Journal Article
Blake, H., Leighton, P., van der Walt, G., & Ravenscroft, A. (2015). Prescribing opioid analgesics for chronic non-malignant pain in general practice - a survey of attitudes and practice. British Journal of Pain, 9(4), https://doi.org/10.1177/2049463715579284

Background: This study replicates a previous postal survey of general practitioners (GPs) to explore whether attitudes to opioid prescribing have changed at a time when the number of opioid prescriptions issued in primary care has increased. Metho... Read More about Prescribing opioid analgesics for chronic non-malignant pain in general practice - a survey of attitudes and practice.

Outpatient versus inpatient uterine polyp treatment for abnormal uterine bleeding: randomised controlled non-inferiority study. (2015)
Journal Article
Cooper, N. A., Clark, T. J., Middleton, L., Diwakar, L., Smith, P., Denny, E., …Thornton, J. (2015). Outpatient versus inpatient uterine polyp treatment for abnormal uterine bleeding: randomised controlled non-inferiority study. BMJ, 350, Article h1398. https://doi.org/10.1136/bmj.h1398

© BMJ Publishing Group Ltd 2015. To compare the effectiveness and acceptability of outpatient polypectomy with inpatient polypectomy. Design Pragmatic multicentre randomised controlled noninferiority study. Setting Outpatient hysteroscopy clinics in... Read More about Outpatient versus inpatient uterine polyp treatment for abnormal uterine bleeding: randomised controlled non-inferiority study..

Source space estimation of oscillatory power and brain connectivity in tinnitus (2015)
Journal Article
Palmer, A. R., Zobay, O., Hall, D. A., Sereda, M., & Adjamian, P. (2015). Source space estimation of oscillatory power and brain connectivity in tinnitus. PLoS ONE, 10(3), Article e0120123. https://doi.org/10.1371/journal.pone.0120123

© 2015 Zobay et al. Tinnitus is the perception of an internally generated sound that is postulated to emerge as a result of structural and functional changes in the brain. However, the precise pathophysiology of tinnitus remains unknown. Llinas' thal... Read More about Source space estimation of oscillatory power and brain connectivity in tinnitus.

Heritability of fractional anisotropy in human white matter: a comparison of Human Connectome Project and ENIGMA-DTI data (2015)
Journal Article
Kochunov, P., Jahanshad, N., Marcus, D., Winkler, A., Sprooten, E., Nichols, T. E., …Van Essen, D. C. (2015). Heritability of fractional anisotropy in human white matter: a comparison of Human Connectome Project and ENIGMA-DTI data. NeuroImage, 111, https://doi.org/10.1016/j.neuroimage.2015.02.050

The degree to which genetic factors influence brain connectivity is beginning to be understood. Large-scale efforts are underway to map the profile of genetic effects in various brain regions. The NIH-funded Human Connectome Project (HCP) is providin... Read More about Heritability of fractional anisotropy in human white matter: a comparison of Human Connectome Project and ENIGMA-DTI data.

Psychosocial work environment and leisure-time physical activity: the Stormont Study (2015)
Journal Article
Houdmont, J., Clemes, S., Munir, F., Wilson, K., Kerr, R., & Addley, K. (2015). Psychosocial work environment and leisure-time physical activity: the Stormont Study. Occupational Medicine, 65(3), https://doi.org/10.1093/occmed/kqu208

Background: Research findings are equivocal on relations between the psychosocial work environment and leisure-time physical activity (LTPA). This might be partly due to studies having focused on a restricted set of psychosocial dimensions, thereby... Read More about Psychosocial work environment and leisure-time physical activity: the Stormont Study.

Patients' use of a home-based virtual reality system to provide rehabilitation of the upper limb following stroke (2015)
Journal Article
Standen, P., Threapleton, K., Connell, L. A., Richardson, A., Brown, D. J., Battersby, S., …Platts, F. (2015). Patients' use of a home-based virtual reality system to provide rehabilitation of the upper limb following stroke. Physical Therapy, 95(3), https://doi.org/10.2522/ptj.20130564

Objective Effectiveness depends on adherence, so did patients use the intervention to the recommended level? If not, what reasons did they give? The purpose of this study was to investigate these and related questions. Design A prospective c... Read More about Patients' use of a home-based virtual reality system to provide rehabilitation of the upper limb following stroke.

Granulocyte-macrophage colony stimulatory factor enhances the pro-inflammatory response of interferon-?-treated macrophages to pseudomonas aeruginosa infection (2015)
Journal Article
Singh, S., Barr, H. L., Liu, Y., Robins, A., Heeb, S., Williams, P., …Martinez-Pomares, L. (2015). Granulocyte-macrophage colony stimulatory factor enhances the pro-inflammatory response of interferon-γ-treated macrophages to pseudomonas aeruginosa infection. PLoS ONE, 10(2), Article e0117447. https://doi.org/10.1371/journal.pone.0117447

Pseudomonas aeruginosa is an opportunistic pathogen that can cause severe infections at compromised epithelial surfaces, such those found in burns, wounds, and in lungs damaged by mechanical ventilation or recurrent infections, particularly in cystic... Read More about Granulocyte-macrophage colony stimulatory factor enhances the pro-inflammatory response of interferon-?-treated macrophages to pseudomonas aeruginosa infection.

Investigating gender differences in the factor structure of the Gudjonsson Compliance Scale (2015)
Journal Article
Drake, K. E., & Egan, V. (2017). Investigating gender differences in the factor structure of the Gudjonsson Compliance Scale. Legal and Criminological Psychology, 22(1), https://doi.org/10.1111/lcrp.12081

Purpose: The Gudjonsson Compliance Scale (GCS) remains, in terms of its psychometrics, an under-researched instrument, in which gender differences in particular have been insufficiently examined. The aim of this research was to therefore investigate... Read More about Investigating gender differences in the factor structure of the Gudjonsson Compliance Scale.

Health state utility values for diabetic retinopathy: protocol for a systematic review and meta-analysis (2015)
Journal Article
Sampson, C. J., Tosh, J. C., Cheyne, C. P., Broadbent, D., & James, M. (2015). Health state utility values for diabetic retinopathy: protocol for a systematic review and meta-analysis. Systematic Reviews, 4(1), Article 15. https://doi.org/10.1186/s13643-015-0006-6

Background People with diabetic retinopathy tend to have lower levels of health-related quality of life than individuals with no retinopathy. Strategies for screening and treatment have been shown to be cost-effective. In order to reduce the bias in... Read More about Health state utility values for diabetic retinopathy: protocol for a systematic review and meta-analysis.

Quantum dot labelling of adenovirus allows for highly sensitive single cell flow and imaging cytometry (2015)
Journal Article
Herod, M. R., Pineda, R. G., Mautner, V., & Onion, D. (2015). Quantum dot labelling of adenovirus allows for highly sensitive single cell flow and imaging cytometry. Small, 11(7), https://doi.org/10.1002/smll.201401885

A quantum dot method for highly efficient labelling of single adenoviral particles is developed. The technique has no impact on viral fitness and allows the imaging and tracking of virus binding and internalisation events using a variety of technique... Read More about Quantum dot labelling of adenovirus allows for highly sensitive single cell flow and imaging cytometry.

Helicobacter pylori infection reduces disease severity in an experimental model of multiple sclerosis (2015)
Journal Article
Cook, K. W., Crooks, J., Hussain, K., O'Brien, K., Braitch, M., Kareem, H., …Gran, B. (2015). Helicobacter pylori infection reduces disease severity in an experimental model of multiple sclerosis. Frontiers in Microbiology, 6, Article 52. https://doi.org/10.3389/fmicb.2015.00052

Recent research has demonstrated that infection with the bacterial pathogen Helicobacter pylori is less common amongst patients with multiple sclerosis (MS), an inflammatory demyelinating disease of the central nervous system (CNS). We aimed to compa... Read More about Helicobacter pylori infection reduces disease severity in an experimental model of multiple sclerosis.

The just-noticeable difference in speech-to-noise ratio (2015)
Journal Article
McShefferty, D., Whitmer, W. M., & Akeroyd, M. A. (2015). The just-noticeable difference in speech-to-noise ratio. Trends in Hearing, 19(1), https://doi.org/10.1177/2331216515572316

Just-noticeable differences (JNDs) have been measured for various features of sounds, but despite its importance to communication, there is no benchmark for what is a just-noticeable—and possibly meaningful—difference in speech-to-noise ratio (SNR).... Read More about The just-noticeable difference in speech-to-noise ratio.

Evaluating a person-centred chronic pain service using indices of reliable and clinically significant change (2015)
Journal Article
Macey, K., Clarke, S., Golijani-Moghaddam, N., & Das Nair, R. (2015). Evaluating a person-centred chronic pain service using indices of reliable and clinically significant change. European journal for person centered healthcare, 3(1), 19. https://doi.org/10.5750/ejpch.v3i1.855

Background: Psychological interventions for chronic pain often require substantial individualisation, which can undermine links with the research evidence on which treatment is based. To ensure patients receive effective therapy, evaluation is needed... Read More about Evaluating a person-centred chronic pain service using indices of reliable and clinically significant change.

Impact of perioperative infarcts after cardiac surgery (2015)
Journal Article
Patel, N., Horsfield, M. A., Banahan, C., Janus, J., Masters, K., Morlese, J., …Chung, E. M. (2015). Impact of perioperative infarcts after cardiac surgery. Stroke, 46(3), https://doi.org/10.1161/STROKEAHA.114.007533

Background and Purpose: Brain injury after cardiac surgery is a serious concern for patients and their families. The purpose of this study was to use 3-T fluid attenuated inversion recovery MRI to characterize new and preexisting cerebral ischemic le... Read More about Impact of perioperative infarcts after cardiac surgery.

Biomaterial modification of urinary catheters with antimicrobials to give long-term broadspectrum antibiofilm activity (2015)
Journal Article
Fisher, L. E., Hook, A. L., Ashraf, W., Yousef, A., Barrett, D. A., Scurr, D. J., …Bayston, R. (2015). Biomaterial modification of urinary catheters with antimicrobials to give long-term broadspectrum antibiofilm activity. Journal of Controlled Release, 202, 57-64. https://doi.org/10.1016/j.jconrel.2015.01.037

© 2015 Published by Elsevier B.V. Catheter-associated urinary tract infection (CAUTI) is the commonest hospital-acquired infection, accounting for over 100,000 hospital admissions within the USA annually. Biomaterials and processes intended to reduce... Read More about Biomaterial modification of urinary catheters with antimicrobials to give long-term broadspectrum antibiofilm activity.

Do orally administered antibiotics reach concentrations in the middle ear sufficient to eradicate planktonic and biofilm bacteria?: a review (2015)
Journal Article
Belfield, K., Bayston, R., Birchall, J., & Daniel, M. (2015). Do orally administered antibiotics reach concentrations in the middle ear sufficient to eradicate planktonic and biofilm bacteria?: a review. International Journal of Pediatric Otorhinolaryngology, 79(3), 296-300. doi:10.1016/j.ijporl.2015.01.003

INTRODUCTION: Infectious conditions of the middle ear are a common and significant cause of morbidity and mortality worldwide. Systemic antibiotics are frequently used, but their effectiveness will depend on whether an adequate antibiotic concentrat... Read More about Do orally administered antibiotics reach concentrations in the middle ear sufficient to eradicate planktonic and biofilm bacteria?: a review.

Normalisation of brain connectivity through compensatory behaviour, despite congenital hand absence (2015)
Journal Article
Hahamy, A., Sotiropoulos, S. N., Henderson Slater, D., Malach, R., Johansen-Berg, H., & Makin, T. R. (2015). Normalisation of brain connectivity through compensatory behaviour, despite congenital hand absence. eLife, 4, Article e04605. https://doi.org/10.7554/eLife.04605.001

Previously we showed, using task-evoked fMRI, that compensatory intact hand usage after amputation facilitates remapping of limb representations in the cortical territory of the missing hand (Makin et al., 2013a). Here we show that compensatory arm u... Read More about Normalisation of brain connectivity through compensatory behaviour, despite congenital hand absence.

Rehabilitation of memory following brain injury (ReMemBrIn): study protocol for a randomised controlled trial (2015)
Journal Article
das Nair, R., Lincoln, N., Ftizsimmons, D., Brain, N., Montgomery, A., Bradshaw, L., …Pink, A. (2015). Rehabilitation of memory following brain injury (ReMemBrIn): study protocol for a randomised controlled trial. Trials, 16(6), https://doi.org/10.1186/1745-6215-16-6

Background Impairments of memory are commonly reported by people with traumatic brain injuries (TBI). Such deficits are persistent, debilitating, and can severely impact quality of life. Currently, many do not routinely receive follow-up appointment... Read More about Rehabilitation of memory following brain injury (ReMemBrIn): study protocol for a randomised controlled trial.

Tel1ATM-mediated interference suppresses clustered meiotic double-strand-break formation (2015)
Journal Article
Garcia, V., Gray, S., Allison, R. M., Cooper, T. J., & Neale, M. J. (2015). Tel1ATM-mediated interference suppresses clustered meiotic double-strand-break formation. Nature, 520(7545), 114-118. https://doi.org/10.1038/nature13993

©2015 Macmillan Publishers Limited. All rights reserved. Meiotic recombination is a critical step in gametogenesis for many organisms, enabling the creation of genetically diverse haploid gametes. In each meiotic cell, recombination is initiated by n... Read More about Tel1ATM-mediated interference suppresses clustered meiotic double-strand-break formation.