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Quantitative assessment of structural and functional changes in CKD using multiparametric renal MRI and the association with biochemical and histological measures (2019)
Journal Article
Buchanan, C. E., Mahmoud, H., Cox, E. F., McCulloch, T., Prestwich, B., Taal, M. W., …Francis, S. T. (in press). Quantitative assessment of structural and functional changes in CKD using multiparametric renal MRI and the association with biochemical and histological measures. Nephrology Dialysis Transplantation,

Background Multiparametric Magnetic Resonance Imaging (MRI) provides the potential for a more comprehensive non-invasive assessment of organ structure and function than individual MRI measures, but has not previously been comprehensively evaluated... Read More

Encouraging performance monitoring promotes proactive control in children (2019)
Journal Article
Hadley, L. V., Acluche, F., & Chevalier, N. (in press). Encouraging performance monitoring promotes proactive control in children. Developmental Science,

Monitoring progression towards one’s goals is essential for efficient cognitive control. Immature performance monitoring may contribute to suboptimal cognitive control engagement in childhood, potentially explaining why children engage control reacti... Read More

A pilot study of visceral fat and its association with adipokines, stool calprotectin and symptoms in patients with diverticulosis (2019)
Journal Article
Murray, K., Hoad, C., Garratt, J., Kaviani, M., Marciani, L., Smith, J., …Spiller, R. (2019). A pilot study of visceral fat and its association with adipokines, stool calprotectin and symptoms in patients with diverticulosis. PLoS ONE, 14(5), doi:10.1371/journal.pone.0216528

Background Complications of diverticular disease are increasingly common, possibly linked to increasing obesity. Visceral fat could contribute to the development of symptomatic diverticular disease through its pro-inflammatory effects. Objective... Read More

Slow cycling intestinal stem cell and Paneth cell responses to Trichinella spiralis infection (2019)
Journal Article
Javkar, T., Hughes, K. R., Sablitzky, F., Behnke, J. M., & Mahida, Y. R. (2019). Slow cycling intestinal stem cell and Paneth cell responses to Trichinella spiralis infection. Parasitology International, doi:10.1016/j.parint.2019.05.001

There is limited information regarding responses by slow cycling stem cells during T. spiralis-induced T-cell mediated intestinal inflammation and how such responses may relate to those of Paneth cells. Transgenic mice, in which doxycycline induces e... Read More

Preoperative high-intensity interval training does not elicit improvements in the cardiorespiratory fitness of colorectal cancer patients (2019)
Journal Article
Boereboom, C. L., Blackwell, J. E., Williams, J. P., Phillips, B. E., & Lund, J. N. (in press). Preoperative high-intensity interval training does not elicit improvements in the cardiorespiratory fitness of colorectal cancer patients. Scandinavian Journal of Medicine and Science in Sports,

Background: Preoperative cardiorespiratory fitness (CRF) in colorectal cancer patients has been shown to affect postoperative outcomes. The aim of this study was to test the feasibility of high-intensity interval training (HIT) for improving fitness... Read More

Quantitative Sensory Testing (QST) and predicting outcomes for musculoskeletal pain, disability and negative affect: a systematic review and meta-analysis (2019)
Journal Article
Georgopoulos, V., Akin-Akinyosoye, K., Zhang, W., Mcwilliams, D. F., Hendrick, P., & Walsh, D. A. (2019). Quantitative Sensory Testing (QST) and predicting outcomes for musculoskeletal pain, disability and negative affect: a systematic review and meta-analysis. PAIN, doi:10.1097/j.pain.0000000000001590

Hypersensitivity due to central pain mechanisms can influence recovery and lead to worse clinical outcomes, but the ability of quantitative sensory testing (QST), an index of sensitisation, to predict outcomes in chronic musculoskeletal disorders rem... Read More

Defining patterns of care in the management of patients with brain metastases in a large oncology centre: a single-centre retrospective audit of 236 cases (2019)
Journal Article
Bentley, R., O'Cathail, M., Aznar-Garcia, L., Crosby, V., Wilcock, A., & Christian, J. (2019). Defining patterns of care in the management of patients with brain metastases in a large oncology centre: a single-centre retrospective audit of 236 cases. European Journal of Cancer Care, doi:10.1111/ecc.13059

Aims: The role of selected treatments for brain metastases (BM) is well documented; however the prevalence of these is not. We report on the patterns of care in the management of BM in a large Oncology centre. Materials and methods: We retrospec... Read More

Implementation in rehabilitation: a roadmap for practitioners and researchers (2019)
Journal Article
Morris, J. H., Bernhardsson, S., Bird, M., Connell, L., Lynch, E., Jarvis, K., …Fisher, R. (2019). Implementation in rehabilitation: a roadmap for practitioners and researchers. Disability and Rehabilitation, 1-10. doi:10.1080/09638288.2019.1587013

Purpose: Despite growth in rehabilitation research, implementing research findings into rehabilitation practice has been slow. This creates inequities for patients and is an ethical issue. However, methods to investigate and facilitate evidence imple... Read More

Development of clinical diagnostic criteria for plaque psoriasis in children: an eDelphi consensus study with the International Psoriasis Council (2019)
Journal Article
Burden‐Teh, E., Thomas, K. S., Gran, S., & Murphy, R. (2019). Development of clinical diagnostic criteria for plaque psoriasis in children: an eDelphi consensus study with the International Psoriasis Council. British Journal of Dermatology, doi:10.1111/bjd.17994

Psoriasis in children can be a challenging diagnosis: the clinical presentation is often more subtle, may occur in covered sites and can be an unexpected diagnosis as psoriasis if often thought to occur at older ages. Poor recognition and delayed dia... Read More

Sexual dimorphism of brown adipose tissue function (2019)
Journal Article
Robinson, L. J., Law, J., Astle, V., Gutiérrez García, M., Ohja, S., Symonds, M. E., …Budge, H. (2019). Sexual dimorphism of brown adipose tissue function. Journal of Pediatrics, doi:10.1016/j.jpeds.2019.03.003

Levothyroxine in women with thyroid peroxidase antibodies before conception (2019)
Journal Article
Dhillon-Smith, R. K., Middleton, L. J., Sunner, K. K., Cheed, V., Baker, K., Farrell-Carver, S., …Coomarasamy, A. (2019). Levothyroxine in women with thyroid peroxidase antibodies before conception. New England Journal of Medicine, 380(14), 1316-1325. doi:10.1056/nejmoa1812537

Background Thyroid peroxidase antibodies are associated with an increased risk of miscarriage and preterm birth, even when thyroid function is normal. Small trials indicate that the use of levothyroxine could reduce the incidence of such adverse out... Read More

Youth drug use in Barbados and England: correlates with online peer influences (2019)
Journal Article
Jules, M. A., Maynard, D. B., & Coulson, N. (2019). Youth drug use in Barbados and England: correlates with online peer influences. Journal of Adolescent Research, doi:10.1177/0743558419839226

This study examined the relationship between susceptibility to drug-related online peer influence on Facebook and offline alcohol, tobacco, and marijuana use among emerging adults (18-24 years) enrolled at the university level in Barbados and England... Read More

SKIP (Supporting Kids with diabetes In Physical activity): Feasibility of a randomised controlled trial of a digital intervention for 9-12 year olds with type 1 diabetes mellitus (2019)
Journal Article
Knox, E., Glazebrook, C., Randell, T., Leighton, P., Guo, B., Greening, J., …Blake, H. (2019). SKIP (Supporting Kids with diabetes In Physical activity): Feasibility of a randomised controlled trial of a digital intervention for 9-12 year olds with type 1 diabetes mellitus. BMC Public Health, 19, 1-14. doi:10.1186/s12889-019-6697-1

Background: Physical activity and self-monitoring are important for children with type 1 diabetes mellitus (T1DM) but it is unclear whether interventions delivered online are feasible, acceptable to patients and efficacious. The aim was to assess the... Read More

MRI of the colon in the pharmaceutical field: the future before us (2019)
Journal Article
Sulaiman, S., & Marciani, L. (2019). MRI of the colon in the pharmaceutical field: the future before us. Pharmaceutics, 11(4), doi:10.3390/pharmaceutics11040146

Oral solid drug formulation is the most common route for administration and it is vital to increase knowledge of the gastrointestinal physiological environment to understand dissolution and absorption processes and to develop reliable biorelevant in... Read More

An antimicrobial impregnated urinary catheter that reduces mineral encrustation and prevents colonisation by multi-drug resistant organisms for up to 12  weeks (2019)
Journal Article
Chen, X., Belfield, K., Chen, X., Smith, E. F., Ashraf, W., & Bayston, R. (2019). An antimicrobial impregnated urinary catheter that reduces mineral encrustation and prevents colonisation by multi-drug resistant organisms for up to 12  weeks. Acta Biomaterialia, 90, 157-168. doi:10.1016/j.actbio.2019.03.042

Two major complications of indwelling urinary catheterisation include infection and mineral encrustation of the catheter. Our antimicrobial urinary catheter (AUC) impregnated with rifampicin, triclosan, and sparfloxacin has demonstrated long-term pro... Read More

Gene-based analysis of angiogenesis, mitochondrial and insulin-related pathways in skeletal muscle of older individuals following nutraceutical supplementation (2019)
Journal Article
Crossland, H., Pereira, S. L., Smith, K., Phillips, B. E., & Atherton, P. J. (2019). Gene-based analysis of angiogenesis, mitochondrial and insulin-related pathways in skeletal muscle of older individuals following nutraceutical supplementation. Journal of Functional Foods, 56, 216-223. doi:10.1016/j.jff.2019.03.022

Cocoa flavanols and fish oil omega-3 fatty acids are two bio-active nutrients that may improve muscle microvascular function, insulin sensitivity and mitochondrial function in older adults. We assessed changes in gene expression of these pathways in... Read More