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Commissioning social care for people with dementia living at home: findings from a national survey (2019)
Journal Article
Davies, S., Hughes, J., Ahmed, S., Clarkson, P., Challis, D., & HoSt-D (Home Support in Dementia) Programme Management Group, . (in press). Commissioning social care for people with dementia living at home: findings from a national survey. International Journal of Geriatric Psychiatry,

Objective: To explore the complexities, circumstances, and range of services commissioned for people with dementia living at home. Methods: A national survey was used to collect data from English local authorities in 2015. Commissioners of servic... Read More

Support Workers in Community Mental Health Teams for Older People: Exploring Sources of Satisfaction and Stress (2019)
Journal Article
Jasper, R., Wilberforce, M., Abendstern, M., Tucker, S., & Challis, D. (2019). Support Workers in Community Mental Health Teams for Older People: Exploring Sources of Satisfaction and Stress. Journal of Long-Term Care, 2019, 111–118

Context: Support workers play an essential role in multidisciplinary community mental health teams for older people (CMHTsOP) in England. However, little is known about how they perceive their role or the impact this has on their levels of stress, we... Read More

Obesity is the most common risk factor for chronic liver disease: Results from risk stratification pathway using transient elastography (2019)
Journal Article
Harris, R., Card, T. R., Delahooke, T., Aithal, G. P., & Guha, I. N. (2019). Obesity is the most common risk factor for chronic liver disease: Results from risk stratification pathway using transient elastography. American Journal of Gastroenterology, doi:10.14309/ajg.0000000000000357

Introduction Obesity has been associated with liver fibrosis yet guidelines do not emphasise it as an independent risk factor in which to have a high index of suspicion of advanced disease. We aimed to elucidate the effect of a raised body mass inde... Read More

A randomized crossover trial assessing the effects of acute exercise on appetite, circulating ghrelin concentrations, and butyrylcholinesterase activity in normal-weight males with variants of the obesity-linked FTO rs9939609 polymorphism (2019)
Journal Article
Jones, J., Dorling, J. L., Clayton, D. J., King, J. A., Carter, W. G., Thackray, A. E., …Stensel, D. J. (2019). A randomized crossover trial assessing the effects of acute exercise on appetite, circulating ghrelin concentrations, and butyrylcholinesterase activity in normal-weight males with variants of the obesity-linked FTO rs9939609 polymorphism. American Journal of Clinical Nutrition, https://doi.org/10.1093/ajcn/nqz188

Pro Con debates in clinical medicine Infection prevention and control in cystic fibrosis: one size fits all? The argument against (2019)
Journal Article
Smyth, A., Smith, S., & Robotham, N. (2019). Pro Con debates in clinical medicine Infection prevention and control in cystic fibrosis: one size fits all? The argument against. Paediatric Respiratory Reviews, doi:10.1016/j.prrv.2019.08.001

As awareness of the risks of cross infection has increased, infection prevention and control measures have become more draconian. Infection control measures can have a profound effect of the organisation and delivery of CF services and on the lives o... Read More

Treatment of Irritable Bowel Syndrome with diarrhoea using Titrated Ondansetron (TRITON): study protocol for a randomised control trial (2019)
Journal Article
Gunn, D., Fried, R., Lalani, R., Farrin, A., Holloway, I., Morris, T., …Spiller, R. (2019). Treatment of Irritable Bowel Syndrome with diarrhoea using Titrated Ondansetron (TRITON): study protocol for a randomised control trial. Trials, 20, doi:10.1186/s13063-019-3562-6

Background – Irritable bowel syndrome with diarrhoea (IBS-D) affects up to 4% of the general population. Symptoms include frequent, loose, or watery stools with associated urgency, resulting in marked reduction of quality of life and loss of work pro... Read More

Comorbid depression and risk of cardiac events and cardiac mortality in people with diabetes: A systematic review and meta-analysis (2019)
Journal Article
Farooqi, A., Khunti, K., Abner, S. C., Gillies, C., Morriss, R., & Seidu, S. (2019). Comorbid depression and risk of cardiac events and cardiac mortality in people with diabetes: A systematic review and meta-analysis. Diabetes Research and Clinical Practice, 156, https://doi.org/10.1016/j.diabres.2019.107816

Objective: To examine the association of comorbid occurrence of diabetes and depression with risk of cardiovascular endpoints including cardiovascular mortality, coronary heart disease and stroke. Research Design and Methods: A systematic review... Read More

Outcomes following an index emergency admission with cholecystitis: a national cohort study (2019)
Journal Article
Mytton, J., Daliya, P., Singh, P., Parsons, S. L., Lobo, D. N., Lilford, R., & Vohra, R. S. (in press). Outcomes following an index emergency admission with cholecystitis: a national cohort study. Annals of Surgery,

Objective The objective of this study was to evaluate the differences between patients who undergo cholecystectomy following index admission for cholecystitis, and those that are managed non-operatively. Summary Background Data Index emergency c... Read More

Role of Self‐Assembly Conditions and Amphiphilic Balance on Nanoparticle Formation of PEG‐PDLLA Copolymers in Aqueous Environments (2019)
Journal Article
Phan, H., Minut, R. I., McCrorie, P., Vasey, C., Larder, R. R., Krumins, E., …Pearce, A. K. (2019). Role of Self‐Assembly Conditions and Amphiphilic Balance on Nanoparticle Formation of PEG‐PDLLA Copolymers in Aqueous Environments. Journal of Polymer Science Part A: Polymer Chemistry, 57(17), 1801-1810. doi:10.1002/pola.29451

The production of well-defined and reproducible poly-meric nanoparticles (NPs), in terms of size and stability in biological environments, is undoubtedly a fundamental challenge in the formulation of novel and more effective nanomedicines. The adopti... Read More

Allogeneic haemopoietic transplantation for acute myeloid leukaemia in second complete remisson: A registry report by the Acute Leukaemia Working Party of the EBMT (2019)
Journal Article
Gilleece, M. H., Labopin, M., Savani, B. N., Yakoub-Agha, I., Socié, G., Gedde-Dahl, T., …Nagler, A. (2019). Allogeneic haemopoietic transplantation for acute myeloid leukaemia in second complete remisson: A registry report by the Acute Leukaemia Working Party of the EBMT. Leukemia, doi:10.1038/s41375-019-0527-4

Allogeneic haemopoietic cell transplant (allo-HCT) may be curative in acute myeloid leukaemia (AML) in second complete remission (CR2) but the impact of reduced intensity (RIC) versus myeloablative conditioning (MAC) is uncertain. The Acute Leukaemia... Read More

The effect of oral essential amino acids on incretin hormone production in youth and ageing (2019)
Journal Article
Abdullah, H., Bass, J., Stokes, T., Gorissen, S., McGlory, C., Phillips, B., …Atherton, P. (2019). The effect of oral essential amino acids on incretin hormone production in youth and ageing. Endocrinology, Diabetes and Metabolism, doi:10.1002/edm2.85

Background: The effect of substantive doses of essential amino acids (EAA) on incretin and insulin production, and the impact of age upon this effect, is ill-defined. Methods: A 15 g oral EAA drink was administered to young (N=8; 26±4.4 y) and old... Read More

Abnormalities of mucosal serotonin metabolism and 5-HT3 receptor subunit 3C polymorphism in irritable bowel syndrome with diarrhoea predict responsiveness to ondansetron (2019)
Journal Article
Gunn, D., Garsed, K., Lam, C., Singh, G., Lingaya, M., Wahl, V., …Spiller, R. (2019). Abnormalities of mucosal serotonin metabolism and 5-HT3 receptor subunit 3C polymorphism in irritable bowel syndrome with diarrhoea predict responsiveness to ondansetron. Alimentary Pharmacology and Therapeutics, 50(5), 538-546. doi:10.1111/apt.15420

Background Irritable bowel syndrome with diarrhoea (IBS‐D) is a common condition, greatly reducing the quality of life with few effective treatment options available. Aims To report the beneficial response shown in our trial with the 5‐hydroyxtr... Read More

Speech, movement and gaze behaviours during dyadic conversation in noise (2019)
Journal Article
Hadley, L. V., Owen Brimijoin, W., & Whitmer, W. M. (2019). Speech, movement and gaze behaviours during dyadic conversation in noise. Scientific Reports, 9, doi:10.1038/s41598-019-46416-0

How do people have conversations in noise and make themselves understood? While many previous studies have investigated speaking and listening in isolation, this study focuses on the behaviour of pairs of individuals in an ecologically valid context.... Read More

Systematic review: Physical activity and fatigue in adults with Inflammatory Bowel Disease (IBD) (2019)
Journal Article
Radford, S. J., Janiszewski, H., & Moran, G. W. (in press). Systematic review: Physical activity and fatigue in adults with Inflammatory Bowel Disease (IBD). Gastrointestinal Nursing,

Background: Fatigue is frequently reported in inflammatory bowel disease (IBD). IBD has been shown to have an impact on, and be impacted by, physical activity levels in IBD patients, Yet, to date, there have been no systematic reviews considering the... Read More

Identifying 'avoidable harm' in family practice: a RAND/UCLA Appropriateness Method consensus study (2019)
Journal Article
Carson-Stevens, A., Campbell, S., Cooper, A., Armstrong, S., Ashcroft, D., Boyd, M., …Avery, A. (in press). Identifying 'avoidable harm' in family practice: a RAND/UCLA Appropriateness Method consensus study. BMC Family Practice,

Background: Health care-related harm is an internationally recognized threat to public health. The United Kingdom’s national health services demonstrate that upwards of 90% of health care encounters can be delivered in ambulatory settings. Other coun... Read More

Age-related differentiation in verbal and visuo-spatial working memory processing in childhood (2019)
Journal Article
Buttelmann, F., Könen, T., Hadley, L. V., Meaney, J., Auyeung, B., Morey, C. C., …Karbach, J. (2019). Age-related differentiation in verbal and visuo-spatial working memory processing in childhood. Psychological Research, doi:10.1007/s00426-019-01219-w

Working memory (WM), a key feature of the cognitive system, allows for maintaining and processing information simultaneously and in a controlled manner. WM processing continuously develops across childhood, with significant increases both in verbal a... Read More

Evaluating a process of academic detailing in primary care: an educational programme for acute kidney injury (2019)
Journal Article
Noble, R. A., McKinnell, J. C., Shaw, S., Bassett, S., Woods, L., Asrar, M., …Selby, N. M. (2019). Evaluating a process of academic detailing in primary care: an educational programme for acute kidney injury. BMC Medical Education, 19, doi:10.1186/s12909-019-1659-y

Background Primary care has a significant role in AKI management: two-thirds of AKI originates in the community. Through academic detailing (an evidence-based educational approach) we aimed to implement and measure the effect of a primary care-based... Read More