All Outputs (1375)

Insight into imiquimod skin permeation and increased delivery using microneedle pre-treatment (2019)
Journal Article
Al-Mayahy, M. H., Sabri, A. H., Rutland, C. S., Holmes, A., McKenna, J., Marlow, M., & Scurr, D. J. (2019). Insight into imiquimod skin permeation and increased delivery using microneedle pre-treatment. European Journal of Pharmaceutics and Biopharmaceutics, 139, 33-43. https://doi.org/10.1016/j.ejpb.2019.02.006

Basal cell carcinoma (BCC) is the most common skin cancer in humans. Topical treatment with imiquimod provides a non-invasive, self-administered treatment with relatively low treatment cost. Despite displaying excellent efficacy, imiquimod is only li... Read More about Insight into imiquimod skin permeation and increased delivery using microneedle pre-treatment.

Mitochondrial respiratory states and rates (2019)
Other
Gnaiger, E., & Chakrabarti, L. (2019). Mitochondrial respiratory states and rates

As the knowledge base and importance of mitochondrial physiology to human health expands, the necessity for harmonizing the terminology concerning mitochondrial respiratory states and rates has become increasingly apparent. The chemiosmotic theory es... Read More about Mitochondrial respiratory states and rates.

Prevalence of feline lungworm Aelurostrongylus abstrusus in England (2019)
Journal Article
Elsheikha, H. M., Wright, I., Wang, B., & Schaper, R. (2019). Prevalence of feline lungworm Aelurostrongylus abstrusus in England. Veterinary parasitology (Amsterdam), 16, 100271. https://doi.org/10.1016/j.vprsr.2019.100271

Infection of cats with lungworm Aelurostrongylus abstrusus has recentlbeen documented in the UK. Here, we aimed to study the prevalence of A. abstrusus in fecal samples from cats across England. A total of 950 fecal samples were collected from cats t... Read More about Prevalence of feline lungworm Aelurostrongylus abstrusus in England.

Comparison of the effects of buprenorphine and methadone in combination with medetomidine followed by intramuscular alfaxalone for anaesthesia of cats undergoing ovariohysterectomy (2019)
Journal Article
Mahdmina, A., Evans, A., Yates, D., & White, K. L. (2019). Comparison of the effects of buprenorphine and methadone in combination with medetomidine followed by intramuscular alfaxalone for anaesthesia of cats undergoing ovariohysterectomy. Journal of Feline Medicine and Surgery, https://doi.org/10.1177/1098612x19826357

Objectives The aim of this study was to compare quality of anaesthesia and analgesia between methadone and buprenorphine in combination with medetomidine after induction with intramuscular (IM) alfaxalone in cats undergoing ovariohysterectomy.... Read More about Comparison of the effects of buprenorphine and methadone in combination with medetomidine followed by intramuscular alfaxalone for anaesthesia of cats undergoing ovariohysterectomy.

African savanna elephants (Loxodonta africana) as an example of a herbivore making movement choices based on nutritional needs (2019)
Journal Article
Sach, F., Dierenfeld, E. S., Langley-Evans, S. C., Watts, M. J., & Yon, L. (2019). African savanna elephants (Loxodonta africana) as an example of a herbivore making movement choices based on nutritional needs. PeerJ, 7, https://doi.org/10.7717/peerj.6260

© 2019 Sach et al. Background: The increasing human population and global intensification of agriculture have had a major impact on the world’s natural ecosystems and caused devastating effects on populations of mega-herbivores such as the African sa... Read More about African savanna elephants (Loxodonta africana) as an example of a herbivore making movement choices based on nutritional needs.

A review of paratuberculosis in dairy herds — Part 1: Epidemiology (2019)
Journal Article
McAloon, C. G., Roche, S., Ritter, C., Barkema, H. W., Whyte, P., More, S. J., …Doherty, M. L. (2019). A review of paratuberculosis in dairy herds — Part 1: Epidemiology. Veterinary Journal, 246, 59-65. https://doi.org/10.1016/j.tvjl.2019.01.010

Bovine paratuberculosis is a chronic infectious disease of cattle caused by Mycobacterium avium subspecies paratuberculosis (MAP). This is the first in a two-part review of the epidemiology and control of paratuberculosis in dairy herds. Paratubercul... Read More about A review of paratuberculosis in dairy herds — Part 1: Epidemiology.

A review of paratuberculosis in dairy herds — Part 2: On-farm control (2019)
Journal Article
McAloon, C. G., Roche, S., Ritter, C., Barkema, H. W., Whyte, P., More, S. J., …Doherty, M. L. (2019). A review of paratuberculosis in dairy herds — Part 2: On-farm control. Veterinary Journal, 246, 54-58. https://doi.org/10.1016/j.tvjl.2019.01.009

Bovine paratuberculosis is a chronic infectious disease of cattle, caused by Mycobacterium avium subspecies paratuberculosis (MAP). This is the second in a two-part review of the epidemiology and control of paratuberculosis in dairy herds. Several ne... Read More about A review of paratuberculosis in dairy herds — Part 2: On-farm control.

Advances in the Development of Anti-Toxoplasma gondii Vaccines: Challenges, Opportunities and Perspectives (2019)
Journal Article
Wang, J., Zhang, N., Li, T., He, J., Elsheikha, H. M., & Zhu, X. (2019). Advances in the Development of Anti-Toxoplasma gondii Vaccines: Challenges, Opportunities and Perspectives. Trends in Parasitology, 35(3), 239-253. https://doi.org/10.1016/j.pt.2019.01.005

Important progress has been made in understanding how immunity is elicited against Toxoplasma gondii - a complex pathogen with multiple mechanisms of immune evasion. Many vaccine candidates have been tested using various strategies in animal models.... Read More about Advances in the Development of Anti-Toxoplasma gondii Vaccines: Challenges, Opportunities and Perspectives.

Introductory Chapter: Veterinary Anatomy and Physiology (2019)
Book Chapter
Kubale, V., Cousins, E., Bailey, C., El-Gendy, S. A., & Rutland, C. S. (2019). Introductory Chapter: Veterinary Anatomy and Physiology. In C. S. Rutland, & V. Kubale (Eds.), Veterinary anatomy and physiology (1-13). InTech. https://doi.org/10.5772/intechopen.82412

Responsible use of antibiotics on sheep farms: application at farm level (2019)
Journal Article
Lovatt, F., Duncan, J., & Hinde, D. (2019). Responsible use of antibiotics on sheep farms: application at farm level. In Practice, 41(1), 23-33. https://doi.org/10.1136/inp.k5370

There is currently global concern over rising levels of antibiotic resistance among commensal and pathogenic bacteria in human and animal populations. Unless urgent action is taken by the medical and veterinary professions, it is thought that we will... Read More about Responsible use of antibiotics on sheep farms: application at farm level.

Do Antiretroviral Drugs Protect From Multiple Sclerosis By Inhibiting Expression Of MS-Associated Retrovirus? (2019)
Journal Article
Morandi, E., Tanasescu, R., Tarlington, R., Constantin-Teodosiu, D., & Gran, B. (2019). Do Antiretroviral Drugs Protect From Multiple Sclerosis By Inhibiting Expression Of MS-Associated Retrovirus?. Frontiers in Immunology, 9, https://doi.org/10.3389/fimmu.2018.03092

The expression of human endogenous retroviruses (HERVs) has been associated with Multiple Sclerosis (MS). The MS-related retrovirus (MSRV/HERV-W) has the potential to activate inflammatory immunity, which could promote both susceptibility and progres... Read More about Do Antiretroviral Drugs Protect From Multiple Sclerosis By Inhibiting Expression Of MS-Associated Retrovirus?.

The interaction between viral and environmental risk factors in the pathogenesis of multiple sclerosis (2019)
Journal Article
Tarlinton, R., Khaibullin, T., Granatov, E., Martynova, E., Rizvanov, A., & Khaiboullina, S. (2019). The interaction between viral and environmental risk factors in the pathogenesis of multiple sclerosis. International Journal of Molecular Sciences, 20(2), 1-16. https://doi.org/10.3390/ijms20020303

Multiple sclerosis (MS) is a chronic debilitating inflammatory disease of unknown ethology targeting the central nervous system (CNS). MS has a polysymptomatic onset and is usually first diagnosed between the ages of 20–40 years. The pathology of the... Read More about The interaction between viral and environmental risk factors in the pathogenesis of multiple sclerosis.

Evolution of gene expression levels in the male reproductive organs of Anopheles mosquitoes (2019)
Journal Article
Izquierdo, A., Fahrenberger, M., Persampieri, T., Benedict, M. Q., Giles, T., Catteruccia, F., …Dottorini, T. (2019). Evolution of gene expression levels in the male reproductive organs of Anopheles mosquitoes. Life Science Alliance, 2(1), Article e00191. https://doi.org/10.26508/lsa.201800191

Modifications in gene expression determine many of the phenotypic differentiations between closely related species. This is particularly evident in reproductive tissues, where evolution of genes is more rapid, facilitating the appearance of distinct... Read More about Evolution of gene expression levels in the male reproductive organs of Anopheles mosquitoes.

The effect of prophylactic treatment with levetiracetam on the incidence of post-attenuation seizures in dogs undergoing surgical management of single congenital extrahepatic portosystemic shunts (2018)
Journal Article
Mullins, R. A., Sanchez Villamil, C., De Rooster, H., Kummeling, A., White, R. N., Thieman Mankin, K. M., …Kirby, B. M. (2019). The effect of prophylactic treatment with levetiracetam on the incidence of post-attenuation seizures in dogs undergoing surgical management of single congenital extrahepatic portosystemic shunts. Veterinary Surgery, 48(2), 164-172. https://doi.org/10.1111/vsu.13141

Objectives: To report (1) the incidence of post-attenuation seizures (PAS) in dogs that underwent single congenital extrahepatic portosystemic shunt (cEHPSS) attenuation and (2) to compare incidence of PAS in dogs that either did or did not receive p... Read More about The effect of prophylactic treatment with levetiracetam on the incidence of post-attenuation seizures in dogs undergoing surgical management of single congenital extrahepatic portosystemic shunts.

Macrophage-derived IL-1? and TNF-? regulate arginine metabolism in neuroblastoma (2018)
Journal Article
Burchill, S. A., Ziegler, D. S., Etchevers, H. C., Norris, M. D., Cheng, P. N., McConville, C. M., …Mussai, F. (2019). Macrophage-derived IL-1β and TNF-α regulate arginine metabolism in neuroblastoma. Cancer Research, 79(3), 611-624. https://doi.org/10.1158/0008-5472.CAN-18-2139

© 2018 American Association for Cancer Research. Neuroblastoma is the most common childhood solid tumor, yet the prognosis for high-risk disease remains poor. We demonstrate here that arginase 2 (ARG2) drives neuroblastoma cell proliferation via regu... Read More about Macrophage-derived IL-1? and TNF-? regulate arginine metabolism in neuroblastoma.

A study of tuberculosis in road traffic-killed badgers on the edge of the British bovine TB epidemic area (2018)
Journal Article
Sandoval Barron, E., Swift, B., Chantrey, J., Christley, R., Gardner, R., Jewell, C., …Bennett, M. (2018). A study of tuberculosis in road traffic-killed badgers on the edge of the British bovine TB epidemic area. Scientific Reports, 8, Article 17206. https://doi.org/10.1038/s41598-018-35652-5

The role of badgers in the geographic expansion of the bovine tuberculosis (bTB) epidemic in England is unknown: indeed there have been few published studies of bTB in badgers outside of the Southwest of England where the infection is now endemic in... Read More about A study of tuberculosis in road traffic-killed badgers on the edge of the British bovine TB epidemic area.

Centralized Trading, Transparency, and Interest Rate Swap Market Liquidity: Evidence from the Implementation of the Dodd–Frank Act (2018)
Journal Article
Benos, E., Payne, R., & Vasios, M. (2020). Centralized Trading, Transparency, and Interest Rate Swap Market Liquidity: Evidence from the Implementation of the Dodd–Frank Act. Journal of Financial and Quantitative Analysis, 55(1), 159-192. https://doi.org/10.1017/S0022109018001527

We use proprietary transaction data on interest rate swaps to assess the effects of centralized trading, as mandated by Dodd-Frank, on market quality. Contracts with the most extensive centralized trading see liquidity metrics improve by between 12%... Read More about Centralized Trading, Transparency, and Interest Rate Swap Market Liquidity: Evidence from the Implementation of the Dodd–Frank Act.

Low accuracy of Bayesian latent class analysis for estimation of herd-level true prevalence under certain disease characteristics—An analysis using simulated data (2018)
Journal Article
McAloon, C. G., Doherty, M. L., Whyte, P., Verdugo, C., Toft, N., More, S. J., …Green, M. J. (2019). Low accuracy of Bayesian latent class analysis for estimation of herd-level true prevalence under certain disease characteristics—An analysis using simulated data. Preventive Veterinary Medicine, 162, 117-125. https://doi.org/10.1016/j.prevetmed.2018.11.014

Estimation of the true prevalence of infected individuals involves the application of a diagnostic test to a population and adjusting according to test performance, sensitivity and specificity. Bayesian latent class analysis for the estimation of her... Read More about Low accuracy of Bayesian latent class analysis for estimation of herd-level true prevalence under certain disease characteristics—An analysis using simulated data.

Veterinary Control of Herd Fertility in Intensively Managed Dairy Herds (2018)
Book Chapter
Hudson, C., Cook, J. G., & Laven, R. (2019). Veterinary Control of Herd Fertility in Intensively Managed Dairy Herds. In Veterinary Reproduction and Obstetrics (467-484). (10th edition). Elsevier. https://doi.org/10.1016/B978-0-7020-7233-8.00025-2

Clinical audit in farm animal veterinary practice. Part 2: conducting the audit (2018)
Journal Article
Waine, K., Dean, R., Hudson, C., & Brennan, M. (2018). Clinical audit in farm animal veterinary practice. Part 2: conducting the audit. In Practice, 40(10), 465-469. https://doi.org/10.1136/inp.k4798

This article, the second in a two-part series providing practical advice for practitioners on carrying out clinical audits in farm animal practice, focuses on the data collection, analysis and discussion steps of clinical audit. Part 1, which was pub... Read More about Clinical audit in farm animal veterinary practice. Part 2: conducting the audit.