Skip to main content

Research Repository

Advanced Search

Browse


Retrospective case series to identify the most common conditions seen ‘out-of-hours’ by first-opinion equine veterinary practitioners (2020)
Journal Article
Boynova, P., Bowden, A., Boynova, P., England, G. C. W., Brennan, M. L., Mair, T. S., …Burford, J. H. (2020). Retrospective case series to identify the most common conditions seen ‘out-of-hours’ by first-opinion equine veterinary practitioners. Veterinary Record, https://doi.org/10.1136/vr.105880

Background: The study aim was to describe conditions seen ‘out-of-hours’ in equine practice. Methods: This was a retrospective case series of first opinion ‘out-of-hours’ cases seen at two equine practices between 2011-2013. Data was retrieved on... Read More about Retrospective case series to identify the most common conditions seen ‘out-of-hours’ by first-opinion equine veterinary practitioners.

Indicators of ‘critical’ outcomes in 941 horses seen ‘out-of-hours’ for colic (2020)
Journal Article
Bowden, A., England, G. C. W., Brennan, M. L., Mair, T. S., Furness, W. A., Freeman, S. L., & Burford, J. H. (2020). Indicators of ‘critical’ outcomes in 941 horses seen ‘out-of-hours’ for colic. Veterinary Record, https://doi.org/10.1136/vr.105881

Background: This study aimed to describe the presentation and outcomes of horses with signs of colic (abdominal pain) seen ‘out-of-hours’ in equine practice. Methods: This was a retrospective study of horses seen ‘out-of-hours’ with colic by two... Read More about Indicators of ‘critical’ outcomes in 941 horses seen ‘out-of-hours’ for colic.

Characterisation of Listeria monocytogenes isolates from cattle using a bovine caruncular epithelial cell model (2020)
Journal Article
Blanchard, A. M., Billenness, R., Warren, J., Glanvill, A., Roden, W., Drinkall, E., …Tötemeyer, S. (2020). Characterisation of Listeria monocytogenes isolates from cattle using a bovine caruncular epithelial cell model. Heliyon, 6(7), https://doi.org/10.1016/j.heliyon.2020.e04476

Listeria monocytogenes is an important foodborne pathogen in human and veterinary health, causing significant morbidity and mortality including abortion. It has a particular tropism for the gravid uterus, however, the route of infection in reproducti... Read More about Characterisation of Listeria monocytogenes isolates from cattle using a bovine caruncular epithelial cell model.

Does manuka honey improve the speed of wound healing in dogs? (2020)
Journal Article
Brennan, M., & Belshaw, Z. (2020). Does manuka honey improve the speed of wound healing in dogs?. Veterinary Record, 187(1), https://doi.org/10.1136/vr.m2538

There is currently no published peer-reviewed evidence comparing the rate of healing of acute superficial wounds in dogs managed with and without medical-grade manuka honey. Therefore, the choice of wound management strategy should be based on other... Read More about Does manuka honey improve the speed of wound healing in dogs?.

Reduction of Salmonella contamination on the surface of chicken skin using bacteriophage (2020)
Journal Article
Atterbury, R. J., Gigante, A. M., Rubio Lozano, M. D. L. S., Méndez Medina, R. D., Robinson, G., Alloush, H., …Allen, V. M. (2020). Reduction of Salmonella contamination on the surface of chicken skin using bacteriophage. Virology Journal, 17, https://doi.org/10.1186/s12985-020-01368-0

Background Enteric infections caused by Salmonella spp. remain a major public health burden worldwide. Chickens are known to be a major reservoir for this zoonotic pathogen. The presence of Salmonella in poultry farms and abattoirs is associated wit... Read More about Reduction of Salmonella contamination on the surface of chicken skin using bacteriophage.

Can Toothache Cause Heartbreak? (2020)
Journal Article
Clark, N., Skinner, Z., & Rutland, C. S. (2020). Can Toothache Cause Heartbreak?. Frontiers for Young Minds, 8, https://doi.org/10.3389/frym.2020.00087

Poor mouth care and heart disease are two major health concerns worldwide. Both conditions occur in humans and in many mammals, including our pets. “Periodontal” is the word used to refer to structures surrounding the teeth, including the gums and bo... Read More about Can Toothache Cause Heartbreak?.

Visual histological assessment of morphological features reflects the underlying molecular profile in invasive breast cancer: a morpho‐molecular study (2020)
Journal Article
Rakha, E. A., Alsaleem, M., Elsharawy, K. A., Toss, M. S., Raafat, S., Mihai, R., …Mongan, N. P. (2020). Visual histological assessment of morphological features reflects the underlying molecular profile in invasive breast cancer: a morpho‐molecular study. Histopathology, https://doi.org/10.1111/his.14199

Background: Tumour genotype and phenotype are related and can predict outcome. In this study, we hypothesised that the visual assessment of breast cancer morphological features can provide valuable insight into underlying molecular profiles. Metho... Read More about Visual histological assessment of morphological features reflects the underlying molecular profile in invasive breast cancer: a morpho‐molecular study.

Immunosuppressive properties of cytochalasin B-induced membrane vesicles of mesenchymal stem cells: comparing with extracellular vesicles derived from mesenchymal stem cells (2020)
Journal Article
Gomzikova, M. O., Aimaletdinov, A. M., Bondar, O. V., Starostina, I. G., Gorshkova, N. V., Neustroeva, O. A., …Rizvanov, A. A. (2020). Immunosuppressive properties of cytochalasin B-induced membrane vesicles of mesenchymal stem cells: comparing with extracellular vesicles derived from mesenchymal stem cells. Scientific Reports, 10, https://doi.org/10.1038/s41598-020-67563-9

Extracellular vesicles derived from mesenchymal stem cells (MSCs) represent a novel approach for regenerative and immunosuppressive therapy. Recently, cytochalasin B-induced microvesicles (CIMVs) were shown to be effective drug delivery mediators. Ho... Read More about Immunosuppressive properties of cytochalasin B-induced membrane vesicles of mesenchymal stem cells: comparing with extracellular vesicles derived from mesenchymal stem cells.

Gene Therapy as a Modern Method of Treating Naturally Occurring Tendinitis and Desmitis in Horses (2020)
Book Chapter
Zakirova, E., Milomir, K., Zhuravleva, M., Rutland, C., & Rizvanov, A. (in press). Gene Therapy as a Modern Method of Treating Naturally Occurring Tendinitis and Desmitis in Horses. In C. Rutland, & A. Rizvanov (Eds.), Equine science. InTech. https://doi.org/10.5772/intechopen.92352

Tendon and ligament injuries have always been complex to treat, with recovery often taking many months, if successful at all. This chapter looks at recent work undertaken using regenerative medicine, specifically gene therapy and the advances that ha... Read More about Gene Therapy as a Modern Method of Treating Naturally Occurring Tendinitis and Desmitis in Horses.

Human Mesenchymal Stem Cells Overexpressing Interleukin 2 Can Suppress Proliferation of Neuroblastoma Cells in Co-Culture and Activate Mononuclear Cells In Vitro (2020)
Journal Article
Chulpanova, D. S., Solovyeva, V. V., James, V., Arkhipova, S. S., Gomzikova, M. O., Garanina, E. E., …Rizvanov, A. A. (2020). Human Mesenchymal Stem Cells Overexpressing Interleukin 2 Can Suppress Proliferation of Neuroblastoma Cells in Co-Culture and Activate Mononuclear Cells In Vitro. Bioengineering, 7(2), https://doi.org/10.3390/bioengineering7020059

High-dose recombinant interleukin 2 (IL2) therapy has been shown to be successful in renal cell carcinoma and metastatic melanoma. However, systemic administration of high doses of IL2 can be toxic, causing capillary leakage syndrome and stimulating... Read More about Human Mesenchymal Stem Cells Overexpressing Interleukin 2 Can Suppress Proliferation of Neuroblastoma Cells in Co-Culture and Activate Mononuclear Cells In Vitro.

Role of Viruses in the Pathogenesis of Multiple Sclerosis (2020)
Journal Article
Tarlinton, R. E., Martynova, E., Rizvanov, A., Khaiboullina, S., & Verma, S. (2020). Role of Viruses in the Pathogenesis of Multiple Sclerosis. Viruses, 12(6), 643. https://doi.org/10.3390/v12060643

Multiple sclerosis (MS) is an immune inflammatory disease, where the underlying etiological cause remains elusive. Multiple triggering factors have been suggested, including environmental, genetic and gender components. However, underlying infectious... Read More about Role of Viruses in the Pathogenesis of Multiple Sclerosis.

"You can be blind because of loving them so much”: The impact on owners in the United Kingdom of living with a dog with osteoarthritis (2020)
Journal Article
Belshaw, Z., Dean, R., & Asher, L. (2020). "You can be blind because of loving them so much”: The impact on owners in the United Kingdom of living with a dog with osteoarthritis. BMC Veterinary Research, 16, https://doi.org/10.1186/s12917-020-02404-5

Background There is growing awareness that caring for a chronically ill pet may have a detrimental impact on their owner’s quality of life. Companion animal orthopaedic disease has received little research interest in this context. Canine osteoarthr... Read More about "You can be blind because of loving them so much”: The impact on owners in the United Kingdom of living with a dog with osteoarthritis.

Mouse Tumor Models for Advanced Cancer Immunotherapy (2020)
Journal Article
Chulpanova, D. S., Kitaeva, K. V., Rutland, C. S., Rizvanov, A. A., & Solovyeva, V. V. (2020). Mouse Tumor Models for Advanced Cancer Immunotherapy. International Journal of Molecular Sciences, 21(11), https://doi.org/10.3390/ijms21114118

Recent advances in the development of new methods of cancer immunotherapy require the production of complex cancer animal models that reliably reflect the complexity of the tumor and its microenvironment. Mice are good animals to create tumor models... Read More about Mouse Tumor Models for Advanced Cancer Immunotherapy.

Homeless people and their dogs: Exploring the nature and impact of the human-companion animal bond (2020)
Journal Article
Scanlon, L., Hobson-West, P., Cobb, K., McBride, A., & Stavisky, J. (in press). Homeless people and their dogs: Exploring the nature and impact of the human-companion animal bond. Anthrozoös,

Homelessness is a pervasive social issue worldwide. In the UK, it is currently estimated that one in two hundred people are homeless, approximating 0.5% of the population. Pet ownership among this group is thought to be commonplace and has been linke... Read More about Homeless people and their dogs: Exploring the nature and impact of the human-companion animal bond.

In vitro activity of Camellia sinensis (green tea) against trophozoites and cysts of Acanthamoeba castellanii (2020)
Journal Article
Fakae, L. B., Stevenson, C. W., Zhu, X. Q., & Elsheikha, H. M. (2020). In vitro activity of Camellia sinensis (green tea) against trophozoites and cysts of Acanthamoeba castellanii. International Journal for Parasitology: Drugs and Drug Resistance, 13, 59-72. https://doi.org/10.1016/j.ijpddr.2020.05.001

© 2020 The Author(s) The effect of Camellia sinensis (green tea) on the growth of Acanthamoeba castellanii trophozoites was examined using a microplate based-Sulforhodamine B (SRB) assay. C. sinensis hot and cold brews at 75% and 100% concentrations... Read More about In vitro activity of Camellia sinensis (green tea) against trophozoites and cysts of Acanthamoeba castellanii.

Immunostimulatory efficacy and protective potential of putative TgERK7 protein in mice experimentally infected by Toxoplasma gondii (2020)
Journal Article
Li, Z. Y., Guo, H. T., Calderón-Mantilla, G., He, J. J., Wang, J. L., Bonev, B. B., …Elsheikha, H. M. (2020). Immunostimulatory efficacy and protective potential of putative TgERK7 protein in mice experimentally infected by Toxoplasma gondii. International Journal of Medical Microbiology, 310(5), https://doi.org/10.1016/j.ijmm.2020.151432

© 2020 The Author(s) The extracellular signal-regulated kinases (ERKs) serve as important determinants of cellular signal transduction pathways, and hence may play important roles during infections. Previous work suggested that putative ERK7 of Toxop... Read More about Immunostimulatory efficacy and protective potential of putative TgERK7 protein in mice experimentally infected by Toxoplasma gondii.

BEVA primary care clinical guidelines: Wound Management in the Horse (2020)
Journal Article
Freeman, S., Ashton, N., Elce, Y., Hammond, A., Hollis, A., & Quinn, G. (2020). BEVA primary care clinical guidelines: Wound Management in the Horse. Equine Veterinary Journal, https://doi.org/10.1111/evj.13289

Methods: Research questions were proposed by a panel of veterinarians, and developed into PICO format. Evidence in the veterinary literature was evaluated using the GRADE evidence-to-decision framework. Searches for human evidence summaries were cond... Read More about BEVA primary care clinical guidelines: Wound Management in the Horse.

Metagenomics reveals impact of geography and acute diarrheal disease on the Central Indian human gut microbiome (2020)
Journal Article
Monaghan, T. M., Sloan, T. J., Stockdale, S. R., Blanchard, A. M., Emes, R. D., Wilcox, M., …Kashyap, R. S. (2020). Metagenomics reveals impact of geography and acute diarrheal disease on the Central Indian human gut microbiome. Gut Microbes, https://doi.org/10.1080/19490976.2020.1752605

© 2020, © 2020 The Author(s). Published with license by Taylor & Francis Group, LLC. Background: The Central Indian gut microbiome remains grossly understudied. Herein, we sought to investigate the burden of antimicrobial resistance and diarrheal d... Read More about Metagenomics reveals impact of geography and acute diarrheal disease on the Central Indian human gut microbiome.


;