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All Outputs (33)

Mapping Polyclonal Antibody Responses to Infection Using Next-Generation Phage Display (2023)
Book Chapter
Tsoumpeli, M. T., Varghese, A., Owen, J. P., Maddison, B. C., Daly, J. M., & Gough, K. C. (2023). Mapping Polyclonal Antibody Responses to Infection Using Next-Generation Phage Display. In M. Hust, & T. S. Lim (Eds.), Phage Display (467-487). Springer US. https://doi.org/10.1007/978-1-0716-3381-6_25

Peptide phage display has historically been used to epitope map monoclonal antibodies. More recently, by coupling this method with next-generation sequencing (so-called next-generation phage display, NGPD) to mass screen peptide binding events, the m... Read More about Mapping Polyclonal Antibody Responses to Infection Using Next-Generation Phage Display.

Cardiovascular Stem Cell Applications in Experimental Animal Models (2023)
Book Chapter
Jeyapalan, J. N., Cockcroft, J., Rizvanov, A. A., Haider, K. H., & Rutland, C. S. (2023). Cardiovascular Stem Cell Applications in Experimental Animal Models. In K. H. Haider (Ed.), Cardiovascular Applications of Stem Cells (465-490). Springer Nature Singapore. https://doi.org/10.1007/978-981-99-0722-9_16

Stem cells are increasingly used in various species for differing diseases, most frequently experimentally. In addition, several animals are also used as models for both veterinary and human medicine. Differing stem cell types have been trialed with... Read More about Cardiovascular Stem Cell Applications in Experimental Animal Models.

Next-Generation Phage Display to Identify Peptide Ligands of Deubiquitinases (2022)
Book Chapter
Spiliotopoulos, A., Maurer, S. K., Tsoumpeli, M. T., Bonfante, J. A. F., Owen, J. P., Gough, K. C., & Dreveny, I. (2023). Next-Generation Phage Display to Identify Peptide Ligands of Deubiquitinases. In J. Maupin-Furlow, & M. J. Edelmann (Eds.), Deubiquitinases: Methods and Protocols (189-218). Humana Press. https://doi.org/10.1007/978-1-0716-2803-4_12

Phage display (PD) is a powerful method and has been extensively used to generate monoclonal antibodies and identify epitopes, mimotopes, and protein interactions. More recently, the combination of next-generation sequencing (NGS) with PD (NGPD) has... Read More about Next-Generation Phage Display to Identify Peptide Ligands of Deubiquitinases.

Evaluation of Current and Future Diagnostic and Prognostic Techniques for Traumatic Pericarditis in Cattle (2022)
Book Chapter
Hall, J., Barker, E., Best, A., & Rutland, C. S. (2022). Evaluation of Current and Future Diagnostic and Prognostic Techniques for Traumatic Pericarditis in Cattle. In C. Rutland, & S. El-Gendy (Eds.), Updates on Veterinary Anatomy and Physiology. InTech. https://doi.org/10.5772/intechopen.106576

Pericarditis in cattle can be classified as traumatic pericarditis (TP), idiopathic haemorrhagic, secondary to neoplasia or septic pericarditis due to haematogenous spread of organisms, such as Colibacilli or Pasturella. In cattle, pericardial diseas... Read More about Evaluation of Current and Future Diagnostic and Prognostic Techniques for Traumatic Pericarditis in Cattle.

Ethnic meat products/Indian subcontinent (2022)
Book Chapter
Bhandare, S., & Gadekar, Y. (2022). Ethnic meat products/Indian subcontinent. In Reference Module in Food Science. Elsevier. https://doi.org/10.1016/b978-0-323-85125-1.00075-2

Ethnic meat products are part of the identity of a local culture, are always popular locally, have evolved over centuries and are passed over from generation to generation. There are several traditional meat products and recipes in the Indian subcont... Read More about Ethnic meat products/Indian subcontinent.

Extracellular Vesicles Derived from Mesenchymal Stem Cells: Biological Activity and Approaches of Large-Scale Production (2022)
Book Chapter
Gomzikova, M. O., James, V., & Rizvanov, A. A. (2022). Extracellular Vesicles Derived from Mesenchymal Stem Cells: Biological Activity and Approaches of Large-Scale Production. In K. H. Haider (Ed.), Handbook of stem cell therapy. Springer Singapore. https://doi.org/10.1007/978-981-16-6016-0_48-1

The discovery of extracellular vesicles has provided an outstanding breakthrough in stem cells and regenerative medicine. It has been shown that cells can transfer information through the secretion of soluble factors, the formation of direct physical... Read More about Extracellular Vesicles Derived from Mesenchymal Stem Cells: Biological Activity and Approaches of Large-Scale Production.

Preclinical Research of Mesenchymal Stem Cell-Based Therapy for Ocular Diseases (2022)
Book Chapter
Zakirova, E., Aimaletdinov, A. M., Malanyeva, A. G., Rutland, С. S., & Rizvanov, A. A. (2022). Preclinical Research of Mesenchymal Stem Cell-Based Therapy for Ocular Diseases. . Springer Singapore. https://doi.org/10.1007/978-981-16-6016-0_12-1

Mesenchymal stem cells (MSC) are specific cell types that enable tissue renewal within the body and are activated during the regeneration processes in response to injury. These cells are present in all human and animal tissues. In medical and biologi... Read More about Preclinical Research of Mesenchymal Stem Cell-Based Therapy for Ocular Diseases.

Endothelial Cell RNA-Seq Data: Differential Expression and Functional Enrichment Analyses to Study Phenotypic Switching (2022)
Book Chapter
Pinel, G. D., Horder, J. L., King, J. R., McIntyre, A., Mongan, N. P., López, G. G., & Benest, A. V. (2022). Endothelial Cell RNA-Seq Data: Differential Expression and Functional Enrichment Analyses to Study Phenotypic Switching. In A. V. Benest (Ed.), Angiogenesis: Methods and Protocol (369-426). Springer. https://doi.org/10.1007/978-1-0716-2059-5_29

RNA-seq is a common approach used to explore gene expression data between experimental conditions or cell types and ultimately leads to information that can shed light on the biological processes involved and inform further hypotheses. While the prot... Read More about Endothelial Cell RNA-Seq Data: Differential Expression and Functional Enrichment Analyses to Study Phenotypic Switching.

Genetics of Asthma: Insights From Genome Wide Association Studies (2021)
Book Chapter
Cooper, R. M., Bingham, K., Portelli, M. A., & Sayers, I. (2022). Genetics of Asthma: Insights From Genome Wide Association Studies. In Encyclopedia of Respiratory Medicine (308-325). (Second Edition). Elsevier. https://doi.org/10.1016/B978-0-08-102723-3.00155-4

Asthma is a heterogeneous respiratory disease that can be influenced by genetic and environmental factors leading to disease susceptibility and progression. Genome-wide association studies (GWAS) of asthma have yielded replicated findings and identif... Read More about Genetics of Asthma: Insights From Genome Wide Association Studies.

Extracellular vesicles, tumor growth, and the metastatic process (2021)
Book Chapter
Wesson, F., Brown, T. J., & James, V. (2022). Extracellular vesicles, tumor growth, and the metastatic process. In D. Heymann (Ed.), Bone Cancer: Bone Sarcomas and Bone Metastases - From Bench to Bedside (275-284). (3rd). Elsevier. https://doi.org/10.1016/B978-0-12-821666-8.00058-X

Extracellular vesicles (EVs) form an important part of cell-to-cell communication, with roles in both health and disease. Within the cancer setting, this heterogenous population of extracellular messengers can have both pro- and antitumorigenic prope... Read More about Extracellular vesicles, tumor growth, and the metastatic process.

Diagnosis, Prognosis, Management, Treatment, Research and Advances in Canine Dilated Cardiomyopathy (2021)
Book Chapter
Simpson, S., Kordtomeikel, K., Wong, S., Bennison, S., El-Gendy, S. A., Cobb, M., & Rutland, C. S. (2021). Diagnosis, Prognosis, Management, Treatment, Research and Advances in Canine Dilated Cardiomyopathy. In C. Rutland (Ed.), Canine Medicine : Recent Topics and Advanced Research (1-22). InTech. https://doi.org/10.5772/intechopen.97682

Dilated cardiomyopathy involves enlargement of the ventricular chamber and systolic dysfunction. The reduction in quality of life and increased levels of congestive heart failure, combined with the high diagnosis rate within the canine population, hi... Read More about Diagnosis, Prognosis, Management, Treatment, Research and Advances in Canine Dilated Cardiomyopathy.

What is the BSAVA lab method performance verification help tool? (2021)
Book Chapter
Graham, P., Williams, T., Arnold, K., & Dormer, L. (2021). What is the BSAVA lab method performance verification help tool?. In BSAVA Lab Method Performance Verification Help Tool. British Small Animal Veterinary Association. https://doi.org/10.22233/9781910443989.1

This document explains the need for verification and how to interpret and use the output obtained from the BSAVA lab method performance verification tool.

The lab equipment verification help tool (2021)
Book Chapter
Graham, P., Williams, T., Arnold, K., & Dormer, L. (2021). The lab equipment verification help tool. In BSAVA Lab Method Performance Verification Help Tool. British Small Animal Veterinary Association. https://doi.org/10.22233/9781910443989.3

The BSAVA Lab Equipment Verification Tool can be used to to verify manufacturer’s claims for automated analyser performance, or alternatively to determine the limitations of your laboratory methods. The tool automatically calculates the total observe... Read More about The lab equipment verification help tool.

Vector Transmission of Animal Viruses (2021)
Book Chapter
Attoui, H., Jaafar, F. M., Fragkoudis, R., & Mertens, P. P. (2021). Vector Transmission of Animal Viruses. In Encyclopedia of Virology (542-551). (Fourth edition). Elsevier. https://doi.org/10.1016/b978-0-12-814515-9.00135-1

Animal “arboviruses” include viruses that are transmitted between their vertebrate hosts by arthropod vectors. They replicate in both their haematophagous arthropod vectors and vertebrate hosts. Vectors become infected after feeding on infected hosts... Read More about Vector Transmission of Animal Viruses.

Bacteriophages as Bio-sanitizers in Food Production and Healthcare Settings (2021)
Book Chapter
Bhandare, S., & Goodridge, L. (2021). Bacteriophages as Bio-sanitizers in Food Production and Healthcare Settings. In D. R. Harper, S. T. Abedon, B. H. Burrowes, & M. L. McConville (Eds.), Bacteriophages: Biology, Technology, Therapy (769-788). Springer International Publishing. https://doi.org/10.1007/978-3-319-41986-2_26

Sanitization is defined as the removal of soil deposits and subsequent application of a sanitizer or disinfectant to reduce the number of residual microorganisms remaining in an environment. Sanitization may be achieved through use of physical (therm... Read More about Bacteriophages as Bio-sanitizers in Food Production and Healthcare Settings.

Gene Therapy as a Modern Method of Treating Naturally Occurring Tendinitis and Desmitis in Horses (2020)
Book Chapter
Zakirova, E., Milomir, K., Zhuravleva, M., Rutland, C., & Rizvanov, A. (2020). Gene Therapy as a Modern Method of Treating Naturally Occurring Tendinitis and Desmitis in Horses. In C. Rutland, & A. Rizvanov (Eds.), Equine science. InTech. https://doi.org/10.5772/intechopen.92352

Tendon and ligament injuries have always been complex to treat, with recovery often taking many months, if successful at all. This chapter looks at recent work undertaken using regenerative medicine, specifically gene therapy and the advances that ha... Read More about Gene Therapy as a Modern Method of Treating Naturally Occurring Tendinitis and Desmitis in Horses.

The Function of Seven Transmembrane Receptors in the Cardiovascular System and Their Role in the Development of Cardiomyopathy (2020)
Book Chapter
Kubale, V., Prozorowska, E., Glocová, K., Slater, L., & Rutland, C. (2020). The Function of Seven Transmembrane Receptors in the Cardiovascular System and Their Role in the Development of Cardiomyopathy. In D. Gaze (Ed.), . United Kingdom: IntechOpen. https://doi.org/10.5772/intechopen.92628

The G-protein-coupled receptors (GPCRs, also called seven-transmembrane receptor, 7TMRs, or heptahelical receptor) are a conserved family of seven transmembrane receptors which are essential not only in the healthy heart and blood vessels but also in... Read More about The Function of Seven Transmembrane Receptors in the Cardiovascular System and Their Role in the Development of Cardiomyopathy.