Twenty amino acids at the C-terminus of PA-X are associated with increased influenza A virus replication and pathogenicity
(2015)
Journal Article
Gao, H., Sun, Y., Liu, X., Sun, H., Hu, J., Wang, J., …He, Q. (2015). Twenty amino acids at the C-terminus of PA-X are associated with increased influenza A virus replication and pathogenicity. Journal of General Virology, 96(8), https://doi.org/10.1099/vir.0.000143
The PA-X protein, arising from ribosomal frameshift during PA translation, was recently discovered in influenza A virus (IAV). The C-terminal domain ‘X’ of PA-X proteins in IAVs can be classified as full-length (61 aa) or truncated (41 aa). In the ma... Read More about Twenty amino acids at the C-terminus of PA-X are associated with increased influenza A virus replication and pathogenicity.