All Outputs (10)

Author response: Kv3.3 subunits control presynaptic action potential waveform and neurotransmitter release at a central excitatory synapse (2022)
Other
Richardson, A., Ciampani, V., Stancu, M., Bondarenko, K., Newton, S., Steinert, J. R., …Forsythe, I. D. (2022). Author response: Kv3.3 subunits control presynaptic action potential waveform and neurotransmitter release at a central excitatory synapse. [elife]

Mitochondrial survivin reduces oxidative phosphorylation in cancer cells by inhibiting mitophagy. (2020)
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Wheatley, S., & Townley, A. R. Mitochondrial survivin reduces oxidative phosphorylation in cancer cells by inhibiting mitophagy

Survivin is a cancer-associated protein that is pivotal for cellular life and death: it is an essential mitotic protein and an inhibitor of apoptosis. In cancer cells, a small pool of survivin localises to the mitochondria, the function of which rema... Read More about Mitochondrial survivin reduces oxidative phosphorylation in cancer cells by inhibiting mitophagy..

Combinatorial metabolic engineering platform enabling stable overproduction of lycopene from carbon dioxide by cyanobacteria (2020)
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Taylor, G. M., & Heap, J. T. Combinatorial metabolic engineering platform enabling stable overproduction of lycopene from carbon dioxide by cyanobacteria

Cyanobacteria are simple, efficient, genetically-tractable photosynthetic microorganisms representing ideal biocatalysts for CO2 capture and conversion, in principle. In practice, genetic instability and low productivity are key, linked problems in e... Read More about Combinatorial metabolic engineering platform enabling stable overproduction of lycopene from carbon dioxide by cyanobacteria.

Selection-based model of prokaryote pangenomes (2019)
Other
Domingo-Sananes, M. R., & McInerney, J. O. (2019). Selection-based model of prokaryote pangenomes

Author response: Efa6 protects axons and regulates their growth and branching by inhibiting microtubule polymerisation at the cortex (2019)
Other
Qu, Y., Hahn, I., Lees, M., Parkin, J., Voelzmann, A., Dorey, K., …Prokop, A. (2019). Author response: Efa6 protects axons and regulates their growth and branching by inhibiting microtubule polymerisation at the cortex

A conserved protein, BcmA, mediates motility, biofilm formation, and host colonisation in Adherent Invasive Escherichia coli (2019)
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Cogger-Ward, R., Collins, A., McLean, D., Dehinsilu, J., & Huett, A. (2019). A conserved protein, BcmA, mediates motility, biofilm formation, and host colonisation in Adherent Invasive Escherichia coli

Adherent Invasive Escherichia coli (AIEC) is a non-diarrhoeagenic intestinal E. coli pathotype associated with Crohn’s Disease. AIEC pathogenesis is characterised by biofilm formation, adhesion to and invasion of intestinal epithelial cells, and intr... Read More about A conserved protein, BcmA, mediates motility, biofilm formation, and host colonisation in Adherent Invasive Escherichia coli.

Whole genome duplication potentiates inter-specific hybridisation and niche shifts in Australian burrowing frogs Neobatrachus (2019)
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Novikova, P. Y., Brennan, I. G., Booker, W., Mahony, M., Doughty, P., Lemmon, A. R., …Donnellan, S. C. (2019). Whole genome duplication potentiates inter-specific hybridisation and niche shifts in Australian burrowing frogs Neobatrachus

Polyploidy plays an important role in evolution because it can lead to increased genetic complexity and speciation. It also provides an extra copy buffer and increases genetic novelty. While both common and well-studied in plants, polyploidy is rare... Read More about Whole genome duplication potentiates inter-specific hybridisation and niche shifts in Australian burrowing frogs Neobatrachus.

Gsmodutils: A python based framework for test-driven genome scale metabolic model development (2018)
Other
Gilbert, J. P., Pearcy, N., Norman, R., Millat, T., Winzer, K., King, J., …Twycross, J. (2018). Gsmodutils: A python based framework for test-driven genome scale metabolic model development

Motivation Genome scale metabolic models (GSMMs) are increasingly important for systems biology and metabolic engineering research as they are capable of simulating complex steady-state behaviour. Constraints based models of this form can include tho... Read More about Gsmodutils: A python based framework for test-driven genome scale metabolic model development.

An illustrated guide to the land snails and slugs of Vietnam (2017)
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Raheem, D. C., Backeljau, T., Pearce-Kelly, P., Taylor, H., Fenn, J., Sutcharit, C., …Naggs, F. (2017). An illustrated guide to the land snails and slugs of Vietnam. [Fieldguide]

A Cdk1 phosphomimic mutant of MCAK impairs microtubule end recognition (2017)
Other
Belsham, H. R., & Friel, C. T. (2017). A Cdk1 phosphomimic mutant of MCAK impairs microtubule end recognition

The microtubule depolymerising kinesin-13, MCAK, is phosphorylated at residue T537 by Cdk1. This is the only known phosphorylation site within MCAK’s motor domain. To understand the impact of phosphorylation by Cdk1 microtubule depolymerisation activ... Read More about A Cdk1 phosphomimic mutant of MCAK impairs microtubule end recognition.