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Systematic review of randomised controlled trials of interventions that aim to reduce the risk, either directly or indirectly, of overweight and obesity in infancy and early childhood (2015)
Journal Article
Redsell, S. A., Edmonds, B., Swift, J. A., Siriwardena, A. N., Weng, S., Nathan, D., & Glazebrook, C. (2016). Systematic review of randomised controlled trials of interventions that aim to reduce the risk, either directly or indirectly, of overweight and obesity in infancy and early childhood. Maternal and Child Nutrition, 12(1), doi:10.1111/mcn.12184

The risk factors for childhood overweight and obesity are known and can be identified antenatally or during infancy, however, the majority of effective interventions are designed for older children. This review identified interventions designed to re... Read More

Transcriptome analysis of mRNA and miRNA in skeletal muscle indicates an important network for differential Residual Feed Intake in pigs (2015)
Journal Article
Jing, L., Wu, H., Miao, Y., Cao, J., Brameld, J. M., Parr, T., & Zhao, S. (2015). Transcriptome analysis of mRNA and miRNA in skeletal muscle indicates an important network for differential Residual Feed Intake in pigs. Scientific Reports, 5, doi:10.1038/srep11953

Feed efficiency (FE) can be measured by feed conversion ratio (FCR) or residual feed intake (RFI). In this study, we measured the FE related phenotypes of 236 castrated purebred Yorkshire boars, and selected 10 extreme individuals with high and low R... Read More

Changes in self-esteem in participants associated with Weightloss and Maintenance of Commercial Weight Management Programme (2015)
Journal Article
Stubbs, J., Hillier, S., Pallister, C., Avery, A., McConnon, A., & Lavin, J. (2015). Changes in self-esteem in participants associated with Weightloss and Maintenance of Commercial Weight Management Programme. Obesity & control therapies : open access, 2(1), doi:10.15226/2374-8354/2/1/00115

Introduction and methods: This study examined associations between weight loss, its maintenance and self-esteem in 292 members of a commercial weight management organisation, Slimming World. Self-esteem was measured with the Rosenberg self-esteem que... Read More

Preparation of iron-enriched baker's yeast and its efficiency in recovery of rats from dietary iron deficiency (2015)
Journal Article
Kyyaly, M. A., Powell, C., & Ramadan, E. (2015). Preparation of iron-enriched baker's yeast and its efficiency in recovery of rats from dietary iron deficiency. Nutrition, 31(9), doi:10.1016/j.nut.2015.04.017

OBJECTIVES Iron is an important mineral, essential for the health and function of mammalian cells. Despite its key role, iron deficiency in humans is common worldwide, often leading to significant health issues within the population. The aim of th... Read More

Lipid-induced insulin resistance is associated with an impaired skeletal muscle protein synthetic response to amino acid ingestion in healthy young men (2015)
Journal Article
Stephens, F. B., Chee, C., Wall, B. T., Murton, A. J., Shannon, C. E., van Loon, L. J., & Tsintzas, K. (2015). Lipid-induced insulin resistance is associated with an impaired skeletal muscle protein synthetic response to amino acid ingestion in healthy young men. Diabetes, 64(5), doi:10.2337/db14-0961

The ability to maintain skeletal muscle mass appears to be impaired in insulin-resistant conditions, such as type 2 diabetes, that are characterized by muscle lipid accumulation. The current study investigated the effect of acutely increasing lipid a... Read More

Protective role of female gender in programmed accelerated renal aging in the rat (2015)
Journal Article
Pijacka, W., Clifford, B., Tilburgs, C., Joles, J. A., Langley-Evans, S. C., & McMullen, S. (2015). Protective role of female gender in programmed accelerated renal aging in the rat. Physiological Reports, 3(4), doi:10.14814/phy2.12342

The aging kidney exhibits a progressive decline in glomerular filtration rate, accompanied by inflammatory and oxidative damage. We hypothesized that accelerated, age-related progression of renal injury is ovarian hormones-dependant. To address this we... Read More

Maternal age effects on myometrial expression of contractile proteins, uterine gene expression, and contractile activity during labor in the rat (2015)
Journal Article
Elmes, M., Szyszka, A., Pauliat, C., Clifford, B., Daniel, Z., Cheng, Z., …McMullen, S. (2015). Maternal age effects on myometrial expression of contractile proteins, uterine gene expression, and contractile activity during labor in the rat. Physiological Reports, 3(4), doi:10.14814/phy2.12305

Advanced maternal age of first time pregnant mothers is associated with prolonged and dysfunctional labor and significant risk of emergency cesarean section. We investigated the influence of maternal age on myometrial contractility, expression of con... Read More

Mathematical modelling of hepatic lipid metabolism (2015)
Journal Article
Pratt, A. C., Wattis, J. A., & Salter, A. M. (2015). Mathematical modelling of hepatic lipid metabolism. Mathematical Biosciences, 262, doi:10.1016/j.mbs.2014.12.012

The aim of this paper is to develop a mathematical model capable of simulating the metabolic response to a variety of mixed meals in fed and fasted conditions with particular emphasis placed on the hepatic triglyceride element of the model. Model va... Read More