Skip to main content

Research Repository

Advanced Search

All Outputs (21)

Convergent genetic and expression data implicate immunity in Alzheimer's disease (2014)
Journal Article
Bossù, P., Tsuang, D. W., Lleò, A., Wallon, D., Todd, S., Dufouil, C., …Holmans, P. (2015). Convergent genetic and expression data implicate immunity in Alzheimer's disease. Alzheimer's and Dementia, 11(6), 658-671. https://doi.org/10.1016/j.jalz.2014.05.1757

© 2015, Elsevier Inc. All rights reserved. Background: Late-onset Alzheimer's disease (AD) is heritable with 20 genes showing genome-wide association in the International Genomics of Alzheimer's Project (IGAP). To identify the biology underly... Read More about Convergent genetic and expression data implicate immunity in Alzheimer's disease.

Possible mechanism behind the hard-to-swallow property of oil seed pastes (2014)
Journal Article
Rosenthal, A. J., & Yilmaz, S. (2015). Possible mechanism behind the hard-to-swallow property of oil seed pastes. International Journal of Food Properties, 18(9), https://doi.org/10.1080/10942912.2013.862633

Roasted and crushed oil-rich seeds, such as sesame paste and peanut butter, both share a common structure and elicit an apparent sensation of thickening in the mouth. Working with sesame paste, as an example, the force needed to compress sesame paste... Read More about Possible mechanism behind the hard-to-swallow property of oil seed pastes.

Phenotypic variation in oronasal perception and the relative effects of PROP and Thermal Taster Status (2014)
Journal Article
Yang, Q., Hollowood, T. A., & Hort, J. (2014). Phenotypic variation in oronasal perception and the relative effects of PROP and Thermal Taster Status. Food Quality and Preference, 38, https://doi.org/10.1016/j.foodqual.2014.05.013

Individual variation in taste perception has long been investigated, particular in relation to PROP taster status (PTS). Recently, a new marker has been identified, Thermal Taster Status (TTS), whereby individuals are categorised as thermal tasters (... Read More about Phenotypic variation in oronasal perception and the relative effects of PROP and Thermal Taster Status.

Amniotic fluid phthalate levels and male fetal gonad function (2014)
Journal Article
Jensen, M. S., Anand-Ivell, R., Nørgaard-Pedersen, B., Jönsson, B. A., Bonde, J. P., Hougaard, D. M., …Toft, G. (2015). Amniotic fluid phthalate levels and male fetal gonad function. Epidemiology, 26(1), 91-99. https://doi.org/10.1097/EDE.0000000000000198

Background: Prenatal exposure to phthalates may pose a threat to human male reproduction. However, additional knowledge about the in vivo effect in humans is needed, and reported associations with genital abnormalities are inconclusive. We aimed to s... Read More about Amniotic fluid phthalate levels and male fetal gonad function.

Use of humanised rat basophilic leukaemia cell line RSATL8 for the assessment of allergenicity of Schistosoma mansoni proteins (2014)
Journal Article
Alcocer, M., Wan, D., Ludolf, F., Alanine, D. G. W., Stretton, O., Ali Ali, E., …Falcone, F. H. (2014). Use of humanised rat basophilic leukaemia cell line RSATL8 for the assessment of allergenicity of Schistosoma mansoni proteins. PLoS Neglected Tropical Diseases, 8(9), 1-13. https://doi.org/10.1371/journal.pntd.0003124

Background Parasite-specific IgE is thought to correlate with protection against Schistosoma mansoni infection or re-infection. Only a few molecular targets of the IgE response in S. mansoni infection have been characterised. A better insight into... Read More about Use of humanised rat basophilic leukaemia cell line RSATL8 for the assessment of allergenicity of Schistosoma mansoni proteins.

Characterisation of a recombinant ?-xylosidase (xylA) from Aspergillus oryzae expressed in Pichia pastoris (2014)
Journal Article
Kirikyali, N., Wood, J., & Connerton, I. F. (2014). Characterisation of a recombinant ?-xylosidase (xylA) from Aspergillus oryzae expressed in Pichia pastoris. AMB Express, 4(68), https://doi.org/10.1186/s13568-014-0068-1

β-xylosidases catalyse the hydrolysis of short chain xylooligosaccharides from their non-reducing ends into xylose. In this study we report the heterologous expression of Aspergillus oryzae β-xylosidase (XylA) in Pichia pastoris under the control of... Read More about Characterisation of a recombinant ?-xylosidase (xylA) from Aspergillus oryzae expressed in Pichia pastoris.

Effect of granule organisation on the behaviour of starches in the NMMO (N-methyl morpholine N-oxide) solvent system (2014)
Journal Article
Koganti, N., Mitchell, J., MacNaughtan, W., Hill, S., & Foster, T. (2015). Effect of granule organisation on the behaviour of starches in the NMMO (N-methyl morpholine N-oxide) solvent system. Carbohydrate Polymers, 116, 103-110. https://doi.org/10.1016/j.carbpol.2014.06.060

The response of starches of different botanical origin to heating in 78% N-methyl morpholine N-oxide (NMMO) is compared with their behaviour in water. For all starches studied an exothermic transition is obtained in the NMMO system rather than the en... Read More about Effect of granule organisation on the behaviour of starches in the NMMO (N-methyl morpholine N-oxide) solvent system.

Genetic diversity of porcine group A rotavirus strains in the UK (2014)
Journal Article
Chandler-Bostock, R., Hancox, L. R., Nawaz, S., Watts, O., Iturriza-Gomara, M., & Mellits, K. M. (2014). Genetic diversity of porcine group A rotavirus strains in the UK. Veterinary Microbiology, 173(1-2), https://doi.org/10.1016/j.vetmic.2014.06.030

Rotavirus is endemic in pig farms where it causes a loss in production. This study is the first to characterise porcine rotavirus circulating in UK pigs. Samples from diarrheic pigs with rotavirus enteritis obtained between 2010 and 2012 were genotyp... Read More about Genetic diversity of porcine group A rotavirus strains in the UK.

Interactions between cellulose ethers and a bile salt in the control of lipid digestion of lipid-based systems (2014)
Journal Article
Torcello-Gómez, A., & Foster, T. (2014). Interactions between cellulose ethers and a bile salt in the control of lipid digestion of lipid-based systems. Carbohydrate Polymers, 113, https://doi.org/10.1016/j.carbpol.2014.06.070

In order to gain new insights into the potential of specific dietary fibres to control lipid digestion, the goal of this work is to study the main interactions between commercial cellulose ethers, as dietary fibre, and a bile salt, as an important du... Read More about Interactions between cellulose ethers and a bile salt in the control of lipid digestion of lipid-based systems.

Ice cream as a vehicle for incorporating health-promoting ingredients: conceptualizationand overview of quality and storage stability aspects (2014)
Journal Article
Soukoulis, C., Fisk, I. D., & Bohn, T. (2014). Ice cream as a vehicle for incorporating health-promoting ingredients: conceptualizationand overview of quality and storage stability aspects. Comprehensive Reviews in Food Science and Food Safety, 13(4), https://doi.org/10.1111/1541-4337.12083

Ice cream is a product with peculiar textural and organoleptic features and is highly appreciated by a very broad spectrum of consumers. Ice cream’s structure and colloidal design, together with its low-temperature storage, renders it a very promisin... Read More about Ice cream as a vehicle for incorporating health-promoting ingredients: conceptualizationand overview of quality and storage stability aspects.

Hydrogen Sulfide Is an Endogenous Regulator of Aging in Caenorhabditis elegans (2014)
Journal Article
Qabazard, B., Li, L., Gruber, J., Peh, M. T., Ng, L. F., Kumar, S. D., …Moore, P. K. (2014). Hydrogen Sulfide Is an Endogenous Regulator of Aging in Caenorhabditis elegans. Antioxidants and Redox Signaling, 20(16), 2621-2630. https://doi.org/10.1089/ars.2013.5448

Aims: To investigate the role of endogenous hydrogen sulfide (H 2S) in the control of aging and healthspan of Caenorhabditis elegans. Results: We show that the model organism, C. elegans, synthesizes H 2S. Three H2S-synthesizing enzymes a... Read More about Hydrogen Sulfide Is an Endogenous Regulator of Aging in Caenorhabditis elegans.

Alternative bacteriophage life cycles: the carrier state of Campylobacter jejuni (2014)
Journal Article
Siringan, P., Connerton, P. L., Cummmings, N. J., & Connerton, I. F. (2014). Alternative bacteriophage life cycles: the carrier state of Campylobacter jejuni. Open Biology, 4(3), Article 130200. https://doi.org/10.1098/rsob.130200

Members of the genus Campylobacter are frequently responsible for human enteric disease, often through consumption of contaminated poultry products. Bacteriophages are viruses that have the potential to control pathogenic bacteria, but understanding... Read More about Alternative bacteriophage life cycles: the carrier state of Campylobacter jejuni.

Stability of Lactobacillus rhamnosus GG in prebiotic edible films (2014)
Journal Article
Soukoulis, C., Behboudi-Jobbehdar, S., Yonekura, L., Parmenter, C., & Fisk, I. D. (2014). Stability of Lactobacillus rhamnosus GG in prebiotic edible films. Food Chemistry, 159, https://doi.org/10.1016/j.foodchem.2014.03.008

The concept of prebiotic edible films as effective vehicles for encapsulating probiotic living cells is presented. Four soluble fibres (inulin, polydextrose, glucose-oligosaccharides and wheat dextrin) were selected as prebiotic co-components of gela... Read More about Stability of Lactobacillus rhamnosus GG in prebiotic edible films.

Innovative ingredients and emerging technologies for controlling ice recrystallisation, texture and structure stability in frozen dairy desserts: a review (2014)
Journal Article
Soukoulis, C., & Fisk, I. D. (2016). Innovative ingredients and emerging technologies for controlling ice recrystallisation, texture and structure stability in frozen dairy desserts: a review. Critical Reviews in Food Science and Nutrition, 56(15), 2543-2559. https://doi.org/10.1080/10408398.2013.876385

Over the past decade, ice cream manufacturers have developed a strong understanding of the functionality of key ingredients and processing, developing effective explanations for the link between structure forming agents, stability mechanisms and perc... Read More about Innovative ingredients and emerging technologies for controlling ice recrystallisation, texture and structure stability in frozen dairy desserts: a review.

Probiotic edible films as a new strategy for developing functional bakery products: the case of pan bread (2014)
Journal Article
Soukoulis, C., Yonekura, L., Gan, H. H., Behboudi-Jobbehdar, S., Parmenter, C., & Fisk, I. D. (2014). Probiotic edible films as a new strategy for developing functional bakery products: the case of pan bread. Food Hydrocolloids, 39, https://doi.org/10.1016/j.foodhyd.2014.01.023

In the present paper, a novel approach for the development of probiotic baked cereal products is presented. Probiotic pan bread constructed by the application of film forming solutions based either on individual hydrogels e.g. 1% w/w sodium alginate... Read More about Probiotic edible films as a new strategy for developing functional bakery products: the case of pan bread.

Protein-like fully reversible tetramerisation and super-association of an aminocellulose (2014)
Journal Article
Nikolajski, M., Adams, G. G., Gillis, R. B., Besong, D. T., Rowe, A. J., Heinze, T., & Harding, S. E. (2014). Protein-like fully reversible tetramerisation and super-association of an aminocellulose. Scientific Reports, 4, Article 3861. https://doi.org/10.1038/srep03861

Unusual protein-like, partially reversible associative behaviour has recently been observed in solutions of the water soluble carbohydrates known as 6-deoxy-6-(?-aminoalkyl)aminocelluloses, which produce controllable self-assembling films for enzyme... Read More about Protein-like fully reversible tetramerisation and super-association of an aminocellulose.

Color influences sensory perception and liking of orange juice (2014)
Journal Article
Fernandez-Vazquez, R., Hewson, L., Fisk, I. D., Hernanz Vila, D., Heredia Mira, F. J., Vicario, I. M., & Hort, J. (2014). Color influences sensory perception and liking of orange juice. Flavour, 3(1), https://doi.org/10.1186/2044-7248-3-1

Background: This study assesses the effect of slight hue variations in orange juice (reddish to greenish) on perceived flavour intensity, sweetness, and sourness, and on expected and actual liking. A commercial orange juice (COJ) was selected as a co... Read More about Color influences sensory perception and liking of orange juice.

Human Testicular Insulin-Like Factor 3 and Endocrine Disrupters (2014)
Book Chapter
Bay, K., & Anand-Ivell, R. (2014). Human Testicular Insulin-Like Factor 3 and Endocrine Disrupters. In Endocrine Disrupters (327-348). Elsevier. https://doi.org/10.1016/B978-0-12-800095-3.00012-2

The hormone insulin-like factor 3 (INSL3) is produced by testicular Leydig cells. Production of INSL3 is dependent on the state of Leydig cell differentiation and is stimulated by the long-term trophic effects of luteinizing hormone. INSL3 is, along... Read More about Human Testicular Insulin-Like Factor 3 and Endocrine Disrupters.