Skip to main content

Research Repository

See what's under the surface

Browse


Glycoconjugate vaccines: some observations on carrier and production methods (2020)
Journal Article
MacCalman, T. E., Phillips-Jones, M. K., & Harding, S. E. (2020). Glycoconjugate vaccines: some observations on carrier and production methods. Biotechnology and Genetic Engineering Reviews, https://doi.org/10.1080/02648725.2019.1703614

Glycoconjugate vaccines use protein carriers to improve the immune response to polysaccharide antigens. The protein component allows the vaccine to interact with T cells, providing a stronger and longer-lasting immune response than a polysaccharide i... Read More about Glycoconjugate vaccines: some observations on carrier and production methods.

Ecosystem services for intensification of agriculture with emphasis on increased nitrogen ecological use efficiency (2020)
Journal Article
Sena, V. G., de Moura, E. G., Macedo, V. R., Aguiar, A. C., Price, A. H., Mooney, S. J., & Calonego, J. C. (2020). Ecosystem services for intensification of agriculture with emphasis on increased nitrogen ecological use efficiency. Ecosphere, 11(2), https://doi.org/10.1002/ecs2.3028

In weathered tropical soil, low nutrient use efficiency can lead to agricultural systems becoming unsustainable. Therefore, tropical agriculture is highly dependent on ecosystem services, such as nutrient recycling and carbon sequestration, to enhanc... Read More about Ecosystem services for intensification of agriculture with emphasis on increased nitrogen ecological use efficiency.

Detrimental effects of uterine disease and lipopolysaccharide on luteal angiogenesis (2020)
Journal Article
Mohammed, Z. A., Robinson, R. S., Harris, R., McLaughlin, Y., Turnbull, K. E., Mann, G., & Woad, K. J. (2020). Detrimental effects of uterine disease and lipopolysaccharide on luteal angiogenesis. Journal of Endocrinology, https://doi.org/10.1530/joe-19-0443

Reproductive tract inflammatory disease (RTID) commonly occurs after the traumatic events of parturition and adversely affects follicular function. This study is the first to describe the cellular and steroidogenic characteristics of corpora lutea fr... Read More about Detrimental effects of uterine disease and lipopolysaccharide on luteal angiogenesis.

Greenhouse gas emissions resulting from conversion of peat swamp forest to oil palm plantation (2020)
Journal Article
Cooper, H. V., Evers, S., Aplin, P., Crout, N., Dahalan, M. P. B., & Sjogersten, S. (2020). Greenhouse gas emissions resulting from conversion of peat swamp forest to oil palm plantation. Nature Communications, 11(1), https://doi.org/10.1038/s41467-020-14298-w

© 2020, The Author(s). Conversion of tropical peat swamp forest to drainage-based agriculture alters greenhouse gas (GHG) production, but the magnitude of these changes remains highly uncertain. Current emissions factors for oil palm grown on drained... Read More about Greenhouse gas emissions resulting from conversion of peat swamp forest to oil palm plantation.

Short-Term Iodine Dynamics in Soil Solution (2020)
Journal Article
Humphrey, O. S., Young, S. D., Crout, N. M., Bailey, E. H., Ander, E. L., & Watts, M. J. (2020). Short-Term Iodine Dynamics in Soil Solution. Environmental Science and Technology, 54(3), 1443-1450. https://doi.org/10.1021/acs.est.9b02296

Assessing the reactions of iodine (I) in soil is critical to evaluate radioiodine exposure and understand soil-to-crop transfer rates. Our mechanistic understanding has been constrained by method limitations in assessing the dynamic interactions of i... Read More about Short-Term Iodine Dynamics in Soil Solution.

Geographical and seasonal variation in Iodine content of cow’s milk in the UK and consequences for the consumer´s supply (2020)
Journal Article
Coneyworth, L. J., Welham, S. J., Coulthard, L. C., Bailey, E. H., Young, S. D., Stubberfield, J., …Homer, E. M. (2020). Geographical and seasonal variation in Iodine content of cow’s milk in the UK and consequences for the consumer´s supply. Journal of Trace Elements in Medicine and Biology, 59, https://doi.org/10.1016/j.jtemb.2020.126453

Background. Dairy products provide a crucial source of dietary iodine for the majority of the UK population, contributing approximately 30-40 % of daily intake. Fluctuations in the iodine content of purchased milk both seasonally and annually implies... Read More about Geographical and seasonal variation in Iodine content of cow’s milk in the UK and consequences for the consumer´s supply.

Early Responses of Brassica oleracea Roots to Zinc Supply Under Sufficient and Sub-Optimal Phosphorus Supply (2020)
Journal Article
Pongrac, P., Fischer, S., Thompson, J. A., Wright, G., & White, P. J. (2020). Early Responses of Brassica oleracea Roots to Zinc Supply Under Sufficient and Sub-Optimal Phosphorus Supply. Frontiers in Plant Science, 10, https://doi.org/10.3389/fpls.2019.01645

© Copyright © 2020 Pongrac, Fischer, Thompson, Wright and White. Shoot zinc (Zn) concentration in Brassica oleracea is affected by soil Zn and phosphorus (P) supply. Most problematic is the negative impact of P fertilizers on Zn concentrations in cro... Read More about Early Responses of Brassica oleracea Roots to Zinc Supply Under Sufficient and Sub-Optimal Phosphorus Supply.

Repurposing Antibacterial AM404 as a Potential Anticancer Drug for Targeting Colorectal Cancer Stem-Like Cells (2019)
Journal Article
Ahmed, M., Jinks, N., Babaei-Jadidi, R., Kashfi, H., Castellanos-Uribe, M., May, S. T., …Nateri, A. S. (2019). Repurposing Antibacterial AM404 as a Potential Anticancer Drug for Targeting Colorectal Cancer Stem-Like Cells. Cancers, 12(1), https://doi.org/10.3390/cancers12010106

Tumour-promoting inflammation is involved in colorectal cancer (CRC) development and therapeutic resistance. However, the antibiotics and antibacterial drugs and signalling that regulate the potency of anticancer treatment upon forced differentiation... Read More about Repurposing Antibacterial AM404 as a Potential Anticancer Drug for Targeting Colorectal Cancer Stem-Like Cells.

Effect of Soybean Oil and Fish Oil on Lipid-Related Transcripts in Subcutaneous Adipose Tissue of Dairy Cows (2019)
Journal Article
Vargas-Bello-Pérez, E., Bionaz, M., Garrido-Sartore, M., Cancino-Padilla, N., Morales, M. S., Romero, J., …Loor, J. J. (2019). Effect of Soybean Oil and Fish Oil on Lipid-Related Transcripts in Subcutaneous Adipose Tissue of Dairy Cows. Animals, 10(1), https://doi.org/10.3390/ani10010054

The objective of this study was to determine the effect of long-term supplementation of unsaturated oil on lipid metabolism and transcription of genes involved in lipid metabolism in subcutaneous adipose tissue (SAT) of mid-lactating dairy cows. The... Read More about Effect of Soybean Oil and Fish Oil on Lipid-Related Transcripts in Subcutaneous Adipose Tissue of Dairy Cows.

Transcriptional plasticity buffers genetic variation in zinc homeostasis (2019)
Journal Article
Pita-Barbosa, A., Ricachenevsky, F. K., Wilson, M., Dottorini, T., & Salt, D. E. (2019). Transcriptional plasticity buffers genetic variation in zinc homeostasis. Scientific Reports, 9, https://doi.org/10.1038/s41598-019-55736-0

In roots of Arabidopsis thaliana, Zn can be either loaded into the xylem for translocation to the shoot or stored in vacuoles. Vacuolar storage is achieved through the action of the Zn/Cd transporter HMA3 (Heavy Metal Atpase 3). The Col-0 accession h... Read More about Transcriptional plasticity buffers genetic variation in zinc homeostasis.

Towards infield, live plant phenotyping using a reduced-parameter CNN (2019)
Journal Article
Atanbori, J., French, A. P., & Pridmore, T. P. (2020). Towards infield, live plant phenotyping using a reduced-parameter CNN. Machine Vision and Applications, 31, https://doi.org/10.1007/s00138-019-01051-7

There is an increase in consumption of agricultural produce as a result of the rapidly growing human population, particularly in developing nations. This has triggered high-quality plant phenotyping re- search to help with the breeding of high yieldi... Read More about Towards infield, live plant phenotyping using a reduced-parameter CNN.

Neglected intermediaries in bioenergy straw supply chains: Understanding the roles of merchants, contractors and agronomists in the England (2019)
Journal Article
Helliwell, R., Seymour, S., & Wilson, P. (2020). Neglected intermediaries in bioenergy straw supply chains: Understanding the roles of merchants, contractors and agronomists in the England. Energy Research and Social Science, 63, https://doi.org/10.1016/j.erss.2019.101387

Outside of Denmark, straw-based bioenergy has seen uneven success across Europe. In the UK, straw-based bioenergy has been positioned as making a potentially important contribution to the UK government's energy and environmental objectives. However,... Read More about Neglected intermediaries in bioenergy straw supply chains: Understanding the roles of merchants, contractors and agronomists in the England.

Prepubertal nutrition alters Leydig cell functional capacity and timing of puberty (2019)
Journal Article
Anand-Ivell, R., Byrne, C. J., Arnecke, J., Fair, S., Lonergan, P., Kenny, D. A., & Richard, I. (2019). Prepubertal nutrition alters Leydig cell functional capacity and timing of puberty. PLoS ONE, 14(11), https://doi.org/10.1371/journal.pone.0225465

Leydig cell functional capacity reflects the numbers and differentiation status of the steroidogenic Leydig cells in the testes and becomes more or less fixed in early adulthood with the final establishment of the hypothalamo-pituitary-gonadal (HPG)... Read More about Prepubertal nutrition alters Leydig cell functional capacity and timing of puberty.

Urine selenium concentration is a useful biomarker for assessing population level selenium status (2019)
Journal Article
Phiri, F. P., Ander, E. L., Lark, R. M., Bailey, E. H., Chilima, B., Gondwe, J., …Broadley, M. R. (2020). Urine selenium concentration is a useful biomarker for assessing population level selenium status. Environment International, 134, https://doi.org/10.1016/j.envint.2019.105218

Plasma selenium (Se) concentration is an established population level biomarker of Se status, especially in Se-deficient populations. Previously observed correlations between dietary Se intake and urinary Se excretion suggest that urine Se concentrat... Read More about Urine selenium concentration is a useful biomarker for assessing population level selenium status.

RootNav 2.0: Deep learning for automatic navigation of complex plant root architectures (2019)
Journal Article
Yasrab, R., Atkinson, J. A., Wells, D. M., French, A. P., Pridmore, T. P., & Pound, M. P. (2019). RootNav 2.0: Deep learning for automatic navigation of complex plant root architectures. GigaScience, 8(11), https://doi.org/10.1093/gigascience/giz123

© The Author(s) 2019. Published by Oxford University Press. BACKGROUND: In recent years quantitative analysis of root growth has become increasingly important as a way to explore the influence of abiotic stress such as high temperature and drought on... Read More about RootNav 2.0: Deep learning for automatic navigation of complex plant root architectures.

Exploring the effects of tomato extract supplementation on cognitive function during exercise and at rest (2019)
Journal Article
Chapman, N. H., Fisk, I., Craigon, J., Towey, C., Grant, I., & Brewer, J. (2019). Exploring the effects of tomato extract supplementation on cognitive function during exercise and at rest. Journal of Nutrition and Health Sciences, 6(2),

It has been reported that tomato (Solanum lycopersicum) fruit extracts may have beneficial effects on cognition. To assess if those effects are reproducible, cognitive function was assessed using a double-blind, randomised control trial design; 17 he... Read More about Exploring the effects of tomato extract supplementation on cognitive function during exercise and at rest.

Developmental roles of AUX1/LAX auxin influx carriers in plants (2019)
Journal Article
Swarup, R., & Bhosale, R. (2019). Developmental roles of AUX1/LAX auxin influx carriers in plants. Frontiers in Plant Science, https://doi.org/10.3389/fpls.2019.01306

Plant hormone auxin regulates several aspects of plant growth and development. Auxin is predominantly synthesized in the shoot apex and developing leaf primordia and from there it is transported to the target tissues e.g. roots. Auxin transport is po... Read More about Developmental roles of AUX1/LAX auxin influx carriers in plants.

Changes in expression of serine biosynthesis and integrated stress response genes during myogenic differentiation of C2C12 cells (2019)
Journal Article
Brearley, M. C., Li, C., Daniel, Z. C., Loughna, P. T., Parr, T., & Brameld, J. M. (2019). Changes in expression of serine biosynthesis and integrated stress response genes during myogenic differentiation of C2C12 cells. Biochemistry and Biophysics Reports, 20, https://doi.org/10.1016/j.bbrep.2019.100694

Skeletal muscle is a highly metabolic and dynamic tissue that is formed through the complex and well-organised process of myogenesis. Although there is a good understanding about the role of the Muscle Regulatory Factors during myogenesis, little is... Read More about Changes in expression of serine biosynthesis and integrated stress response genes during myogenic differentiation of C2C12 cells.