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Repurposing Antibacterial AM404 as a Potential Anticancer Drug for Targeting Colorectal Cancer Stem-Like Cells (2019)
Journal Article
Ahmed, M., Jinks, N., Babaei-Jadidi, R., Kashfi, H., Castellanos-Uribe, M., May, S. T., …Nateri, A. S. (2019). Repurposing Antibacterial AM404 as a Potential Anticancer Drug for Targeting Colorectal Cancer Stem-Like Cells. Cancers, 12(1), Article 106. https://doi.org/10.3390/cancers12010106

Tumour-promoting inflammation is involved in colorectal cancer (CRC) development and therapeutic resistance. However, the antibiotics and antibacterial drugs and signalling that regulate the potency of anticancer treatment upon forced differentiation... Read More about Repurposing Antibacterial AM404 as a Potential Anticancer Drug for Targeting Colorectal Cancer Stem-Like Cells.

Effect of Soybean Oil and Fish Oil on Lipid-Related Transcripts in Subcutaneous Adipose Tissue of Dairy Cows (2019)
Journal Article
Vargas-Bello-Pérez, E., Bionaz, M., Garrido-Sartore, M., Cancino-Padilla, N., Morales, M. S., Romero, J., …Loor, J. J. (2019). Effect of Soybean Oil and Fish Oil on Lipid-Related Transcripts in Subcutaneous Adipose Tissue of Dairy Cows. Animals, 10(1), https://doi.org/10.3390/ani10010054

The objective of this study was to determine the effect of long-term supplementation of unsaturated oil on lipid metabolism and transcription of genes involved in lipid metabolism in subcutaneous adipose tissue (SAT) of mid-lactating dairy cows. The... Read More about Effect of Soybean Oil and Fish Oil on Lipid-Related Transcripts in Subcutaneous Adipose Tissue of Dairy Cows.

Mutation in OsCADT1 enhances cadmium tolerance and enriches selenium in rice grain (2019)
Journal Article
Chen, J., Huang, X., Salt, D. E., & Zhao, F. (2020). Mutation in OsCADT1 enhances cadmium tolerance and enriches selenium in rice grain. New Phytologist, 226(3), 838-850. https://doi.org/10.1111/nph.16404

•How cadmium (Cd) tolerance in rice is regulated remains poorly understood. We used a forward genetic approach to investigate Cd tolerance in rice. •Using root elongation assay, we isolated a rice mutant with enhanced Cd tolerance, cadt1, from an EMS... Read More about Mutation in OsCADT1 enhances cadmium tolerance and enriches selenium in rice grain.

Transcriptional plasticity buffers genetic variation in zinc homeostasis (2019)
Journal Article
Pita-Barbosa, A., Ricachenevsky, F. K., Wilson, M., Dottorini, T., & Salt, D. E. (2019). Transcriptional plasticity buffers genetic variation in zinc homeostasis. Scientific Reports, 9, Article 19482. https://doi.org/10.1038/s41598-019-55736-0

In roots of Arabidopsis thaliana, Zn can be either loaded into the xylem for translocation to the shoot or stored in vacuoles. Vacuolar storage is achieved through the action of the Zn/Cd transporter HMA3 (Heavy Metal Atpase 3). The Col-0 accession h... Read More about Transcriptional plasticity buffers genetic variation in zinc homeostasis.

Towards infield, live plant phenotyping using a reduced-parameter CNN (2019)
Journal Article
Atanbori, J., French, A. P., & Pridmore, T. P. (2020). Towards infield, live plant phenotyping using a reduced-parameter CNN. Machine Vision and Applications, 31, Article 2. https://doi.org/10.1007/s00138-019-01051-7

There is an increase in consumption of agricultural produce as a result of the rapidly growing human population, particularly in developing nations. This has triggered high-quality plant phenotyping re- search to help with the breeding of high yieldi... Read More about Towards infield, live plant phenotyping using a reduced-parameter CNN.

Neglected intermediaries in bioenergy straw supply chains: Understanding the roles of merchants, contractors and agronomists in England (2019)
Journal Article
Helliwell, R., Seymour, S., & Wilson, P. (2020). Neglected intermediaries in bioenergy straw supply chains: Understanding the roles of merchants, contractors and agronomists in England. Energy Research and Social Science, 63, https://doi.org/10.1016/j.erss.2019.101387

Outside of Denmark, straw-based bioenergy has seen uneven success across Europe. In the UK, straw-based bioenergy has been positioned as making a potentially important contribution to the UK government's energy and environmental objectives. However,... Read More about Neglected intermediaries in bioenergy straw supply chains: Understanding the roles of merchants, contractors and agronomists in England.

Elemental signatures of an Amazonian Dark Earth as result of its formation process (2019)
Journal Article
Barbosa, J. Z., Motta, A. C. V., Corrêa, R. S., Melo, V. D. F., Muniz, A. W., Martins, G. C., …Broadley, M. R. (2020). Elemental signatures of an Amazonian Dark Earth as result of its formation process. Geoderma, 361, Article 114085. https://doi.org/10.1016/j.geoderma.2019.114085

© 2019 Elsevier B.V. Amazonian Dark Earths (ADEs) are soils studied for archaeological purposes and as a potentially agricultural model for the humid tropic. We investigated the chemical composition of an ADE in comparison to an adjacent Ultisol with... Read More about Elemental signatures of an Amazonian Dark Earth as result of its formation process.

Prepubertal nutrition alters Leydig cell functional capacity and timing of puberty (2019)
Journal Article
Anand-Ivell, R., Byrne, C. J., Arnecke, J., Fair, S., Lonergan, P., Kenny, D. A., & Richard, I. (2019). Prepubertal nutrition alters Leydig cell functional capacity and timing of puberty. PLoS ONE, 14(11), https://doi.org/10.1371/journal.pone.0225465

Leydig cell functional capacity reflects the numbers and differentiation status of the steroidogenic Leydig cells in the testes and becomes more or less fixed in early adulthood with the final establishment of the hypothalamo-pituitary-gonadal (HPG)... Read More about Prepubertal nutrition alters Leydig cell functional capacity and timing of puberty.

Urine selenium concentration is a useful biomarker for assessing population level selenium status (2019)
Journal Article
Phiri, F. P., Ander, E. L., Lark, R. M., Bailey, E. H., Chilima, B., Gondwe, J., …Broadley, M. R. (2020). Urine selenium concentration is a useful biomarker for assessing population level selenium status. Environment International, 134, Article 105218. https://doi.org/10.1016/j.envint.2019.105218

Plasma selenium (Se) concentration is an established population level biomarker of Se status, especially in Se-deficient populations. Previously observed correlations between dietary Se intake and urinary Se excretion suggest that urine Se concentrat... Read More about Urine selenium concentration is a useful biomarker for assessing population level selenium status.

RootNav 2.0: Deep learning for automatic navigation of complex plant root architectures (2019)
Journal Article
Yasrab, R., Atkinson, J. A., Wells, D. M., French, A. P., Pridmore, T. P., & Pound, M. P. (2019). RootNav 2.0: Deep learning for automatic navigation of complex plant root architectures. GigaScience, 8(11), https://doi.org/10.1093/gigascience/giz123

© The Author(s) 2019. Published by Oxford University Press. BACKGROUND: In recent years quantitative analysis of root growth has become increasingly important as a way to explore the influence of abiotic stress such as high temperature and drought on... Read More about RootNav 2.0: Deep learning for automatic navigation of complex plant root architectures.

Exploring the effects of tomato extract supplementation on cognitive function during exercise and at rest (2019)
Journal Article
Chapman, N. H., Fisk, I., Craigon, J., Towey, C., Grant, I., & Brewer, J. (2019). Exploring the effects of tomato extract supplementation on cognitive function during exercise and at rest. Journal of Nutrition and Health Sciences, 6(2),

It has been reported that tomato (Solanum lycopersicum) fruit extracts may have beneficial effects on cognition. To assess if those effects are reproducible, cognitive function was assessed using a double-blind, randomised control trial design; 17 he... Read More about Exploring the effects of tomato extract supplementation on cognitive function during exercise and at rest.

Developmental roles of AUX1/LAX auxin influx carriers in plants (2019)
Journal Article
Swarup, R., & Bhosale, R. (2019). Developmental roles of AUX1/LAX auxin influx carriers in plants. Frontiers in Plant Science, 10, https://doi.org/10.3389/fpls.2019.01306

Plant hormone auxin regulates several aspects of plant growth and development. Auxin is predominantly synthesized in the shoot apex and developing leaf primordia and from there it is transported to the target tissues e.g. roots. Auxin transport is po... Read More about Developmental roles of AUX1/LAX auxin influx carriers in plants.

Antigen array for serological diagnosis and novel allergen identification in severe equine asthma (2019)
Journal Article
White, S. J., Moore-Colyer, M., Marti, E., Hannant, D., Gerber, V., Coüetil, L., …Alcocer, M. (2019). Antigen array for serological diagnosis and novel allergen identification in severe equine asthma. Scientific Reports, 9, Article 15170. https://doi.org/10.1038/s41598-019-51820-7

Severe equine asthma (sEA), which closely resembles human asthma, is a debilitating and performance-limiting allergic respiratory disorder which affects 14% of horses in the Northern Hemisphere and is associated with increased allergen-specific immun... Read More about Antigen array for serological diagnosis and novel allergen identification in severe equine asthma.

Changes in expression of serine biosynthesis and integrated stress response genes during myogenic differentiation of C2C12 cells (2019)
Journal Article
Brearley, M. C., Li, C., Daniel, Z. C., Loughna, P. T., Parr, T., & Brameld, J. M. (2019). Changes in expression of serine biosynthesis and integrated stress response genes during myogenic differentiation of C2C12 cells. Biochemistry and Biophysics Reports, 20, Article 100694. https://doi.org/10.1016/j.bbrep.2019.100694

Skeletal muscle is a highly metabolic and dynamic tissue that is formed through the complex and well-organised process of myogenesis. Although there is a good understanding about the role of the Muscle Regulatory Factors during myogenesis, little is... Read More about Changes in expression of serine biosynthesis and integrated stress response genes during myogenic differentiation of C2C12 cells.

Soil strength influences wheat root interactions with soil macropores (2019)
Journal Article
Atkinson, J. A., Hawkesford, M. J., Whalley, W. R., Zhou, H., & Mooney, S. J. (2020). Soil strength influences wheat root interactions with soil macropores. Plant, Cell and Environment, 43(1), 235-245. https://doi.org/10.1111/pce.13659

Deep rooting is critical for access to water and nutrients found in subsoil. However, damage to soil structure and the natural increase in soil strength with depth, often impedes root penetration. Evidence suggests that roots use macropores (soil cav... Read More about Soil strength influences wheat root interactions with soil macropores.

The Relationship Between Wort Sugar Concentration and Yeast Carbon Partitioning during Brewing Fermentations (2019)
Journal Article
Zhuang, S., Smart, K., & Powell, C. D. (2019). The Relationship Between Wort Sugar Concentration and Yeast Carbon Partitioning during Brewing Fermentations. Journal of The American Society of Brewing Chemists, 77(4), 225-234. https://doi.org/10.1080/03610470.2019.1666630

High gravity (HG) and very high gravity (VHG) fermentations are increasingly attractive within the brewing industry as a means of optimizing process efficiency and energy-saving. However, the use of highly concentrated worts is concomitant with a num... Read More about The Relationship Between Wort Sugar Concentration and Yeast Carbon Partitioning during Brewing Fermentations.

Assessment of potentially toxic elements in vegetables cultivated in urban and peri-urban sites in the Kurdistan region of Iraq and implications for human health (2019)
Journal Article
Hawrami, K., Crout, N., Shaw, G., & Bailey, E. H. (2020). Assessment of potentially toxic elements in vegetables cultivated in urban and peri-urban sites in the Kurdistan region of Iraq and implications for human health. Environmental Geochemistry and Health, 42(5), 1359–1385. https://doi.org/10.1007/s10653-019-00426-z

Vegetable fields in and around urban areas in the Kurdistan region of Iraq may have higher than background concentrations of potentially toxic elements (PTEs) from contamination sources including municipal waste disposal and waste water used for irri... Read More about Assessment of potentially toxic elements in vegetables cultivated in urban and peri-urban sites in the Kurdistan region of Iraq and implications for human health.

The impact of exposure to cafeteria diet during pregnancy or lactation on offspring growth and adiposity before weaning (2019)
Journal Article
George, G., Draycott, S. A., Muir, R., Clifford, B., Elmes, M. J., & Langley-Evans, S. C. (2019). The impact of exposure to cafeteria diet during pregnancy or lactation on offspring growth and adiposity before weaning. Scientific Reports, 9, Article 14173. https://doi.org/10.1038/s41598-019-50448-x

Exposure to maternal obesity during early-life can have adverse consequences for offspring growth and adiposity. We aimed to assess the relative contributions of exposure to maternal obesity, induced by a highly varied cafeteria diet, during pregnanc... Read More about The impact of exposure to cafeteria diet during pregnancy or lactation on offspring growth and adiposity before weaning.

The impact of reduced red and processed meat consumption on cardiovascular risk factors; an intervention trial in healthy volunteers (2019)
Journal Article
Simpson, E. J., Clark, M., Razak, A. A., & Salter, A. (2019). The impact of reduced red and processed meat consumption on cardiovascular risk factors; an intervention trial in healthy volunteers. Food and Function, 2019(10), 6690-6698. https://doi.org/10.1039/C9FO00758J

Meat represents an important part of the diet for many adults, supplying essential amino acids and micronutrients. However, high red and processed meat (RPM) intake is implicated in the development of cardiovascular disease and dyslipidemia. This stu... Read More about The impact of reduced red and processed meat consumption on cardiovascular risk factors; an intervention trial in healthy volunteers.