A clinical evaluation of the pharmacokinetics and pharmacodynamics of intravenous alfaxalone in cyclodextrin in male and female rats following a loading dose and constant rate infusion
(2017)
Journal Article
White, K. L., Paine, S., & Harris, J. (2017). A clinical evaluation of the pharmacokinetics and pharmacodynamics of intravenous alfaxalone in cyclodextrin in male and female rats following a loading dose and constant rate infusion. Veterinary Anaesthesia and Analgesia, 44(4), https://doi.org/10.1016/j.vaa.2017.01.001
Objective: To characterise, as a clinical study, the pharmacokinetics and pharmacodynamics and describe the hypnotic effect of the neurosteroid alfaxalone (3?-hydroxy-5 ?-pregnane-11, 20-dione) formulated with 2-hydroxypropyl-?-cyclodextrin in male a... Read More about A clinical evaluation of the pharmacokinetics and pharmacodynamics of intravenous alfaxalone in cyclodextrin in male and female rats following a loading dose and constant rate infusion.