All Outputs (3)

Male seminal parameters are not associated with Leydig cell functional capacity in men (2021)
Journal Article
Anand?Ivell, R., Tremellen, K., Soyama, H., Enki, D., & Ivell, R. (2021). Male seminal parameters are not associated with Leydig cell functional capacity in men. Andrology, 9(4), 1126-1136. https://doi.org/10.1111/andr.13001

Background: Insulin-like peptide 3 (INSL3) is a constitutive, secreted peptide produced in the male uniquely by the Leydig cells of the testes. It is a biomarker for Leydig cell functional capacity, which is a measure of the numbers and differentiati... Read More about Male seminal parameters are not associated with Leydig cell functional capacity in men.

Prepubertal nutrition alters Leydig cell functional capacity and timing of puberty (2019)
Journal Article
Anand-Ivell, R., Byrne, C. J., Arnecke, J., Fair, S., Lonergan, P., Kenny, D. A., & Richard, I. (2019). Prepubertal nutrition alters Leydig cell functional capacity and timing of puberty. PLoS ONE, 14(11), https://doi.org/10.1371/journal.pone.0225465

Leydig cell functional capacity reflects the numbers and differentiation status of the steroidogenic Leydig cells in the testes and becomes more or less fixed in early adulthood with the final establishment of the hypothalamo-pituitary-gonadal (HPG)... Read More about Prepubertal nutrition alters Leydig cell functional capacity and timing of puberty.

Theca cell INSL3 and steroids together orchestrate the growing bovine antral follicle (2017)
Journal Article
Dai, Y., Ivell, R., & Anand-Ivell, R. (2017). Theca cell INSL3 and steroids together orchestrate the growing bovine antral follicle. Frontiers in Physiology, 8, https://doi.org/10.3389/fphys.2017.01033

Insulin-like peptide 3 (INSL3) and its specific receptor RXFP2 are both expressed by theca interna cells of the growing antral follicle where they form an essential regulatory element in the production of the steroid precursor androstenedione. Using... Read More about Theca cell INSL3 and steroids together orchestrate the growing bovine antral follicle.