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Bacteriophage therapy to reduce colonization of campylobacter jejuni in broiler chickens before slaughter (2021)
Journal Article
D’angelantonio, D., Scattolini, S., Boni, A., Neri, D., Di Serafino, G., Connerton, P., …Aprea, G. (2021). Bacteriophage therapy to reduce colonization of campylobacter jejuni in broiler chickens before slaughter. Viruses, 13(8), Article 1428. https://doi.org/10.3390/v13081428

Campylobacteriosis is the most commonly reported gastrointestinal disease in humans. Campybacter jejuni is the main cause of the infection, and bacterial colonization in broiler chickens is widespread and difficult to prevent, leading to high risk of... Read More about Bacteriophage therapy to reduce colonization of campylobacter jejuni in broiler chickens before slaughter.

Acetate and auto-inducing peptide are independent triggers of quorum sensing in Lactobacillus plantarum (2021)
Journal Article
Meng, F., Lu, F., Du, H., Nie, T., Zhu, X., Connerton, I. F., …Lu, Y. (2021). Acetate and auto-inducing peptide are independent triggers of quorum sensing in Lactobacillus plantarum. Molecular Microbiology, 116(1), 298-310. https://doi.org/10.1111/mmi.14709

The synthesis of plantaricin in Lactobacillus plantarum is regulated by quorum sensing. However, the nature of the extra-cytoplasmic (EC) sensing domain of the histidine kinase (PlnB1) and the ability to recognize the auto-inducing peptide PlnA1 is n... Read More about Acetate and auto-inducing peptide are independent triggers of quorum sensing in Lactobacillus plantarum.

Encapsulation of E. coli phage ZCEC5 in chitosan-alginate beads as a delivery system in phage therapy (2019)
Journal Article
Abdelsattar, A. S., Abdelrahmen, F., Dawoud, A., Connerton, I. F., & El-Shibiny, A. (2019). Encapsulation of E. coli phage ZCEC5 in chitosan-alginate beads as a delivery system in phage therapy. Applied Microbiology and Biotechnology, 9, Article 87. https://doi.org/10.1186/s13568-019-0810-9

© 2019, The Author(s). Bacteriophages can be used successfully to treat pathogenic bacteria in the food chain including zoonotic pathogens that colonize the intestines of farm animals. However, harsh gastric conditions of low pH and digestive enzyme... Read More about Encapsulation of E. coli phage ZCEC5 in chitosan-alginate beads as a delivery system in phage therapy.

Pilot study of long-term anaesthesia in broiler chickens (2016)
Journal Article
O'Kane, P. M., Connerton, I. F., & White, K. L. (2016). Pilot study of long-term anaesthesia in broiler chickens. Veterinary Anaesthesia and Analgesia, 43(1), 72-75. https://doi.org/10.1111/vaa.12305

Objective: To provide stable anaesthesia of long duration in broiler chickens in order to perform a terminal caecal ligated loop procedure. Study design: Prospective experimental study. Animals: Seven clinically healthy broiler chickens (Gallus... Read More about Pilot study of long-term anaesthesia in broiler chickens.

The complete plasmid sequences of Salmonella enterica serovar Typhimurium U288 (2014)
Journal Article
Hooton, S. P., Timms, A. R., Cummings, N. J., Moreton, J., Wilson, R., & Connerton, I. F. (2014). The complete plasmid sequences of Salmonella enterica serovar Typhimurium U288. Plasmid, 76, 32-39. https://doi.org/10.1016/j.plasmid.2014.08.002

Salmonella enterica Serovar Typhimurium U288 is an emerging pathogen of pigs. The strain contains three plasmids of diverse origin that encode traits that are of concern for food security and safety, these include antibiotic resistant determinants, a... Read More about The complete plasmid sequences of Salmonella enterica serovar Typhimurium U288.

Food safety organisations in Saudi Arabia – organisational, historical and future analysis (2014)
Journal Article
Al-Mutairi, S., Connerton, I., & Dingwall, R. (2015). Food safety organisations in Saudi Arabia – organisational, historical and future analysis. Food Control, 47, 478-486. https://doi.org/10.1016/j.foodcont.2014.07.047

Food safety organisations around the world are increasingly seeking to develop public policies to protect society, improve the economy, and ensure food safety and quality, by reducing the risks of food-borne illnesses, commercial adulteration, and fo... Read More about Food safety organisations in Saudi Arabia – organisational, historical and future analysis.

Complete genome sequence of universal bacteriophage host strain Campylobacter jejuni subsp. jejuni PT14 (2013)
Journal Article
Brathwaite, K. J., Siringan, P., Moreton, J., Wilson, R., & Connerton, I. F. (2013). Complete genome sequence of universal bacteriophage host strain Campylobacter jejuni subsp. jejuni PT14. Genome Announcements, 1(6), 1-2. https://doi.org/10.1128/genomea.00969-13

Campylobacter jejuni strain PT14 is a clinical isolate previously used to propagate bacteriophages in the United Kingdom phage typing scheme. The strain has proven useful in the isolation of Campylobacter bacteriophages from several sources, and it f... Read More about Complete genome sequence of universal bacteriophage host strain Campylobacter jejuni subsp. jejuni PT14.

Complete genome sequence of Salmonella enterica serovar Typhimurium U288 (2013)
Journal Article
Hooton, S. P., Timms, A. R., Moreton, J., Wilson, R., & Connerton, I. F. (2013). Complete genome sequence of Salmonella enterica serovar Typhimurium U288. Genome Announcements, 1(4), https://doi.org/10.1128/genomeA.00467-13

Salmonella enterica serovar Typhimurium U288 has firmly established itself within the United Kingdom pig production industry. The prevalence of this highly pathogenic multidrug-resistant serovar at such a critical point in the food chain is therefore... Read More about Complete genome sequence of Salmonella enterica serovar Typhimurium U288.

A suggested classification for two groups of Campylobacter myoviruses (2013)
Journal Article
Javed, M. A., Ackermann, H., Azeredo, J., Carvalho, C. M., Connerton, I., Evoy, S., …Kropinski, A. M. (2014). A suggested classification for two groups of Campylobacter myoviruses. Archives of Virology, 159(1), 181-190. https://doi.org/10.1007/s00705-013-1788-2

Most Campylobacter bacteriophages isolated to date have long contractile tails and belong to the family Myoviridae. Based on their morphology, genome size and endonuclease restriction profile, Campylobacter phages were originally divided into three g... Read More about A suggested classification for two groups of Campylobacter myoviruses.

Carbohydrate binding and gene expression by in vitro and in vivo propagated Campylobacter jejuni after Immunomagnetic Separation (2012)
Journal Article
King, R. M., Day, C. J., Hartley-Tassell, L. E., Connerton, I. F., Tiralongo, J., Mcguckin, M. A., & Korolik, V. (2012). Carbohydrate binding and gene expression by in vitro and in vivo propagated Campylobacter jejuni after Immunomagnetic Separation. Journal of Basic Microbiology, 53(3), 240-250. https://doi.org/10.1002/jobm.201100466

Campylobacter jejuni is an important human food-borne intestinal pathogen, however relatively little is known about its mechanisms of pathogenesis or pathogen-host interactions. To monitor changes in gene expression and glycan binding of C. jejuni wi... Read More about Carbohydrate binding and gene expression by in vitro and in vivo propagated Campylobacter jejuni after Immunomagnetic Separation.