Skip to main content

Research Repository

Advanced Search

All Outputs (5)

The role of the cingulate cortex in the generation of motor tics and the experience of the premonitory urge-to-tic in Tourette syndrome (2021)
Journal Article
Jackson, S. R., Sigurdsson, H. P., Dyke, K., Condon, M., & Jackson, G. M. (2021). The role of the cingulate cortex in the generation of motor tics and the experience of the premonitory urge-to-tic in Tourette syndrome. Journal of Neuropsychology, 15(3), 340-362. https://doi.org/10.1111/jnp.12242

Tourette syndrome (TS) is a neurological disorder of childhood onset that is characterized by the occurrence of motor and vocal tics. TS is associated with cortical-striatal-thalamic-cortical circuit [CSTC] dysfunction and hyper-excitability of corti... Read More about The role of the cingulate cortex in the generation of motor tics and the experience of the premonitory urge-to-tic in Tourette syndrome.

Entraining Movement-Related Brain Oscillations to Suppress Tics in Tourette Syndrome (2020)
Journal Article
Morera Maiquez, B., Sigurdsson, H. P., Dyke, K., Clarke, E., McGrath, P., Pasche, M., …Jackson, S. R. (2020). Entraining Movement-Related Brain Oscillations to Suppress Tics in Tourette Syndrome. Current Biology, 30(12), 2334-2342.e3. https://doi.org/10.1016/j.cub.2020.04.044

Tourette syndrome (TS) is a neuropsychiatric disorder characterised by the occurrence of vocal and motor tics. Tics are involuntary, repetitive, movements and vocalisations that occur in bouts, typically many times in a single day, and are often prec... Read More about Entraining Movement-Related Brain Oscillations to Suppress Tics in Tourette Syndrome.

A feasibility study for somatomotor cortical mapping in Tourette syndrome using neuronavigated transcranial magnetic stimulation (2020)
Journal Article
Sigurdsson, H. P., Jackson, G. M., Jackson, S. R., Dyke, K., & Kim, S. (2020). A feasibility study for somatomotor cortical mapping in Tourette syndrome using neuronavigated transcranial magnetic stimulation. Cortex, 129, 175-187. https://doi.org/10.1016/j.cortex.2020.04.014

Tourette syndrome (TS) is a hyperkinetic movement disorder characterised by the occurrence of chronic motor and vocal tics, and is associated with alterations in the balance of excitatory and inhibitory signalling within key brain networks; in partic... Read More about A feasibility study for somatomotor cortical mapping in Tourette syndrome using neuronavigated transcranial magnetic stimulation.

Activation induced changes in GABA: functional MRS at 7 T with MEGA-sLASER (2017)
Journal Article
Chen, C., Sigurdsson, H. P., Pépés, S. E., Auer, D. P., Morris, P. G., Morgan, P. S., …Jackson, S. R. (2017). Activation induced changes in GABA: functional MRS at 7 T with MEGA-sLASER. NeuroImage, 156, 207-213. https://doi.org/10.1016/j.neuroimage.2017.05.044

Functional magnetic resonance spectroscopy (fMRS) has been used to assess the dynamic metabolic responses of the brain to a physiological stimulus non-invasively. However, only limited information on the dynamic functional response of γ-aminobutyric... Read More about Activation induced changes in GABA: functional MRS at 7 T with MEGA-sLASER.

Comparing GABA-­dependent physiological measures of inhibition with proton magnetic resonance spectroscopy measurement of GABA using ultra-­high-­field MRI (2017)
Journal Article
Dyke, K., Pépés, S. E., Chen, C., Kim, S., Sigurdsson, H. P., Draper, A., …Jackson, S. R. (2017). Comparing GABA-­dependent physiological measures of inhibition with proton magnetic resonance spectroscopy measurement of GABA using ultra-­high-­field MRI. NeuroImage, 152, 360-370. https://doi.org/10.1016/j.neuroimage.2017.03.011

Imbalances in glutamatergic (excitatory) and GABA (inhibitory) signalling within key brain networks are thought to underlie many brain and mental health disorders, and for this reason there is considerable interest in investigating how individual var... Read More about Comparing GABA-­dependent physiological measures of inhibition with proton magnetic resonance spectroscopy measurement of GABA using ultra-­high-­field MRI.