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Prehospital transdermal glyceryl trinitrate in pateints with ultra-acute presumed stroke (RIGHT-2): an ambulance-based randomised, sham-controlled, blinded, phase 3 trial (2019)
Journal Article
Bath, P. M., Scutt, P., Anderson, C. S., Ankolekar, S., Appleton, J. P., Berge, E., …Sprigg, N. (2019). Prehospital transdermal glyceryl trinitrate in pateints with ultra-acute presumed stroke (RIGHT-2): an ambulance-based randomised, sham-controlled, blinded, phase 3 trial. Lancet, doi:10.1016/S0140-6736(19)30194-1

Background High blood pressure is common in acute stroke and is a predictor of poor outcome; however, large trials of lowering blood pressure have given variable results, and the management of high blood pressure in ultra-acute stroke remains uncle... Read More

Human tissue kallikrein in the treatment of acute ischemic stroke (2019)
Journal Article
Alexander-Curtis, M., Pauls, R., Chao, J., Volpi, J. J., Appel, S. H., Bath, P. M., & Verdoorn, T. A. (2019). Human tissue kallikrein in the treatment of acute ischemic stroke. Therapeutic Advances in Neurological Disorders, 12, 1-15. doi:10.1177/1756286418821918

Acute ischemic stroke (AIS) remains a major cause of death and disability throughout the world. The most severe form of stroke results from large vessel occlusion of the major branches of the Circle of Willis. The treatment strategies currently avail... Read More

Swallowing therapy for dysphagia in acute and subacute stroke (2018)
Journal Article
Bath, P. M., Lee, H. S., & Everton, L. F. (2018). Swallowing therapy for dysphagia in acute and subacute stroke. Cochrane Database of Systematic Reviews, doi:10.1002/14651858.CD000323.pub3

Background: Dysphagia (swallowing problems), which is common after stroke, is associated with increased risk of death or dependency, occurrence of pneumonia, poor quality of life, and longer hospital stay. Treatments provided to improve dysphagia are... Read More