Research Repository

See what's under the surface


Proactive assessment of obesity risk during infancy (ProAsk): a qualitative study of parents’ and professionals’ perspectives on an mHealth intervention. (2019)
Journal Article
Rose, J., Glazebrook, C., Wharrad, H., Siriwardena, A. N., Swift, J. A., Nathan, D., …Redsell, S. (in press). Proactive assessment of obesity risk during infancy (ProAsk): a qualitative study of parents’ and professionals’ perspectives on an mHealth intervention. BMC Public Health,

Background: Prevention of childhood obesity is a public health priority. Interventions that establish healthy growth trajectories early in life promise lifelong benefits to health and wellbeing. Proactive Assessment of Obesity Risk during Infancy... Read More

A tailored digital behaviour change intervention with e-referral system to increase attendance at NHS Stop Smoking Services (The MyWay Project): study protocol for a randomised controlled feasibility trial (2019)
Journal Article
Fulton, E. A., Newby, K., Gokal, K., Kwah, K., Schumacher, L., Jackson, L. J., …Brown, K. E. (in press). A tailored digital behaviour change intervention with e-referral system to increase attendance at NHS Stop Smoking Services (The MyWay Project): study protocol for a randomised controlled feasibility trial. BMJ Open,

Introduction: In the UK, smokers who use Stop Smoking Services (SSS) are four times more likely to stop smoking than smokers who do not. Attendance has declined, warranting the development of interventions to address this. StopAppTM is a novel, bri... Read More

Stop smoking practitioner consensus on barriers and facilitators to smoking cessation in pregnancy and how to address these: a modified Delphi survey (2019)
Journal Article
Fergie, L., Campbell, K., Coleman-Haynes, T., Ussher, M., Cooper, S., & Coleman, T. (2019). Stop smoking practitioner consensus on barriers and facilitators to smoking cessation in pregnancy and how to address these: a modified Delphi survey. Addictive Behaviors Reports, 9, doi:10.1016/j.abrep.2019.100164

Introduction: Pregnant women can experience barriers and facilitators towards achieving smoking cessation. We sought consensus from smoking cessation practitioners on how influential pre-identified barriers and facilitators can be on pregnant women'... Read More

Sub-optimal cholesterol response to initiation of statins and future risk of cardiovascular disease (2019)
Journal Article
Akyea, R., Kai, J., Qureshi, N., Iyen, B., & Weng, S. (in press). Sub-optimal cholesterol response to initiation of statins and future risk of cardiovascular disease. Heart,

Objective: To assess low-density lipoprotein cholesterol (LDL-C) response in patients after initiation of statins, and future risk of CVD. Method: Prospective cohort study of 165,411 primary care patients, from the UK Clinical Practice Research... Read More

Processing discharge summaries in general practice: a qualitative interview study with GPs and practice managers (2019)
Journal Article
Spencer, R. A., Rodgers, S., Salema, N., Campbell, S. M., & Avery, A. J. (2019). Processing discharge summaries in general practice: a qualitative interview study with GPs and practice managers. BJGP Open, doi:10.3399/bjgpopen18X101625

Background Discharge summaries are essential for communicating patient information from secondary care to general practice on hospital discharge. Although there has been extensive research into their design and completion in secondary care very l... Read More

Assessing the severity of Type 2 diabetes using clinical data-based measures: a systematic review (2019)
Journal Article
Zghebi, S. S., Panagioti, M., Rutter, M. K., Ashcroft, D. M., van Marwijk, H., Salisbury, C., …Kontopantelis, E. (2019). Assessing the severity of Type 2 diabetes using clinical data-based measures: a systematic review. Diabetic Medicine, doi:10.1111/dme.13905

Aims: To identify and critically appraise measures that use clinical data to grade the severity of Type 2 diabetes. Methods: We searched MEDLINE, Embase and PubMed between inception and June 2018. Studies reporting on clinical data‐based diabetes‐sp... Read More

Use of hormone replacement therapy and risk of venous thromboembolism: nested case-control studies using the QResearch and CPRD databases (2019)
Journal Article
Vinogradova, Y., Coupland, C., & Hippisley-Cox, J. (2019). Use of hormone replacement therapy and risk of venous thromboembolism: nested case-control studies using the QResearch and CPRD databases. BMJ, 364, doi:10.1136/bmj.k4810

Objectives: To assess risk of venous thromboembolism associated with different types of hormone replacement therapy. Design: Two nested case-control studies. Setting: UK general practices contributing to QResearch or Clinical Practice Research... Read More

Attitudes to E-Cigarettes and Cessation Support for Pregnant Women from English Stop Smoking Services: A Mixed Methods Study (2019)
Journal Article
Cooper, S., Orton, S., Campbell, K., Ussher, M., Coleman-Haynes, N., Whitemore, R., …Coleman, T. (2019). Attitudes to E-Cigarettes and Cessation Support for Pregnant Women from English Stop Smoking Services: A Mixed Methods Study. International Journal of Environmental Research and Public Health, 16(1), doi:10.3390/ijerph16010110

Smoking in pregnancy remains a public health problem. In the UK e-cigarettes are the most popular aid to quitting smoking outside of pregnancy, but we don’t know the extent of e-cigarette use in pregnancy or how English Stop Smoking Services (SSS) re... Read More

A systematic review of behaviour change techniques within interventions to prevent return to smoking postpartum (2018)
Journal Article
Brown, T. J., Hardeman, W., Bauld, L., Holland, R., Maskrey, V., Naughton, F., …Notley, C. (2019). A systematic review of behaviour change techniques within interventions to prevent return to smoking postpartum. Addictive Behaviors, 92, 236-243. doi:10.1016/j.addbeh.2018.12.031

Introduction: There is no routine support to prevent postpartum smoking relapse, due to lack of effective interventions. Previous reviews have identified behaviour change techniques (BCTs) within pregnancy cessation trials to specify which components... Read More

Healthcare utilisation, morbidities and alcohol use monitoring prior to alcoholic psychosis diagnosis (2018)
Journal Article
Otete, H., Fleming, K. M., West, J., & Orton, E. (2018). Healthcare utilisation, morbidities and alcohol use monitoring prior to alcoholic psychosis diagnosis. Alcohol and Alcoholism, doi:10.1093/alcalc/agy085

Aims: This study aimed to describe healthcare utilisation, morbidities and monitoring of alcohol use in patients prior to a diagnosis of alcoholic psychosis in order to inform the early identification of patients at risk. Method: Using linked gene... Read More

The relationship between patients’ illness beliefs and recovery after stroke (2018)
Journal Article
Aujla, N., Walker, M., Vedhara, K., & Sprigg, N. (2018). The relationship between patients’ illness beliefs and recovery after stroke. Psychology, Health and Medicine, doi:10.1080/13548506.2018.1557712

The Common Sense Model (CSM) is a useful framework for understanding mood and treatment adherence amongst survivors in the acute phase of stroke. CSM stroke studies have thus far focused on the single outcomes, mood and medication adherence, neglecti... Read More

Identifying effective behavior change techniques for alcohol and illicit substance use during pregnancy: a systematic review (2018)
Journal Article
Fergie, L., Cambbell, K., Coleman-Haynes, T., Ussher, M., Cooper, S., & Coleman, T. (2018). Identifying effective behavior change techniques for alcohol and illicit substance use during pregnancy: a systematic review. Annals of Behavioral Medicine, 1-13. doi:10.1093/abm/kay085

Background: During pregnancy, consuming alcohol and using illicit drugs can have serious health implications for both mother and child. Behavioral change interventions, especially those underpinned by theoretical constructs, can be effective in reduc... Read More

Developing a learning health system: insights from a qualitative process evaluation of a pharmacist-led electronic audit and feedback intervention to improve medication safety in primary care. (2018)
Journal Article
Jeffries, M., Keers, R. N., Phipps, D. L., Williams, R., Brown, B., Avery, A. J., …Ashcroft, D. M. (2018). Developing a learning health system: insights from a qualitative process evaluation of a pharmacist-led electronic audit and feedback intervention to improve medication safety in primary care. PLoS ONE, 13(10), doi:10.1371/journal.pone.0205419

Introduction: Developments in information technology offer opportunities to enhance medication safety in primary care. We evaluated the implementation and adoption of a complex pharmacist-led intervention involving the use of an electronic audit and... Read More

A dynamic, modifiable model for estimating cost-effectiveness of smoking cessation interventions in pregnancy: application to an RCT of self-help delivered by text message (2018)
Journal Article
Jones, M., Smith, M., Lewis, S., Parrott, S., & Coleman, T. (2019). A dynamic, modifiable model for estimating cost-effectiveness of smoking cessation interventions in pregnancy: application to an RCT of self-help delivered by text message. Addiction, 114(2), 353-365. doi:10.1111/add.14476

Background/Aims: Previous evaluations of smoking cessation interventions in pregnancy have several limitations. Our solution to these limitations is the Economics of Smoking in Pregnancy (ESIP) model which estimates the lifetime cost-effectiveness of... Read More

Comparison of nicotine exposure during pregnancy when smoking and abstinent with nicotine replacement therapy: systematic review and meta-analysis (2018)
Journal Article
Hickson, C., Lewis, S., Campbell, K. A., Cooper, S., Berlin, I., Claire, R., …Coleman, T. (2019). Comparison of nicotine exposure during pregnancy when smoking and abstinent with nicotine replacement therapy: systematic review and meta-analysis. Addiction, 114(3), 406-424. doi:10.1111/add.14473

Background and aims: Smoking during pregnancy is strongly associated with negative pregnancy and perinatal outcomes. Some guidelines recommend nicotine replacement therapy (NRT) for smoking cessation during pregnancy but adherence with NRT is general... Read More

Keeping active: maintenance of physical activity after exercise programs for older adults (2018)
Journal Article
Kendrick, D., Orton, E., Lafond, N., Audsley, S., Maula, A., Morris, R., …Iliffe, S. (2018). Keeping active: maintenance of physical activity after exercise programs for older adults. Public Health, 164, (118-127). doi:10.1016/j.puhe.2018.08.003. ISSN 0033-3506

Objectives: To explore factors associated with maintenance of moderate-to-vigorous physical activity (MVPA) in community-dwelling adults aged ≥65 years after completing a 24-week exercise programme. Study design: Cohort study nested within a randomi... Read More

SMASH! The Salford medication safety dashboard (2018)
Journal Article
Williams, R., Keers, R., Gude, W. T., Jeffries, M., Davies, C., Brown, B., …Peek, N. (2018). SMASH! The Salford medication safety dashboard. Journal of Innovation in Health Informatics, 25(3), 183-193. doi:10.14236/jhi.v25i3.1015

Background: Patient safety is vital to well-functioning health systems. A key component is safe prescribing, particularly in primary care where most medications are prescribed. Previous research demonstrated that the number of patients exposed to pot... Read More

Lung cancer screening: does pulmonary nodule detection affect a range of smoking behaviours? (2018)
Journal Article
Clark, M. E., Young, B., Bedford, L. E., Robertson, J. F., das Nair, R., Vedhara, K., …Kendrick, D. (2018). Lung cancer screening: does pulmonary nodule detection affect a range of smoking behaviours?. Journal of Public Health, doi:10.1093/pubmed/fdy158. ISSN 1741-3842

Background Lung cancer screening can reduce lung cancer mortality by 20%. Screen-detected abnormalities may provide teachable moments for smoking cessation. This study assesses impact of pulmonary nodule detection on smoking behaviours within the fi... Read More

Screening for familial hypercholesterolaemia in primary care: time for general practice to play its part (2018)
Journal Article
Brett, T., Qureshi, N., Gidding, S., & Watts, G. F. (2018). Screening for familial hypercholesterolaemia in primary care: time for general practice to play its part. Atherosclerosis, 277, 399-406. doi:10.1016/j.atherosclerosis.2018.08.019

Fifty per cent of first-degree relatives of index cases with familial hypercholesterolemia (FH) inherit the disorder. Despite cascade screening being the most cost-effective method for detecting new cases, only a minority of individuals with FH are c... Read More

Variation in geographical treatment intensity affects survival of non-small cell lung cancer patients in England. (2018)
Journal Article
Tataru, D., Spencer, K., Bates, A., Wieczorek, A., Jack, R. H., Peake, M. D., …Lüchtenborg, M. (2018). Variation in geographical treatment intensity affects survival of non-small cell lung cancer patients in England. Cancer Epidemiology, 57, (13-23). doi:10.1016/j.canep.2018.09.001. ISSN 1877-7821

Objectives: We aimed to determine the geographical variation in the proportion of non-small cell lung cancer (NSCLC) patients undergoing curative treatment and assess the relationship between treatment access rates and survival outcomes. Methods:... Read More