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All Outputs (15)

Mental health in the UK during the COVID-19 pandemic: cross-sectional analyses from a community cohort study (2020)
Journal Article
Jia, R., Ayling, K., Chalder, T., Massey, A., Broadbent, E., Coupland, C., & Vedhara, K. (2020). Mental health in the UK during the COVID-19 pandemic: cross-sectional analyses from a community cohort study. BMJ Open, 10(9), Article e040620. https://doi.org/10.1136/bmjopen-2020-040620

Objectives: Previous pandemics have resulted in significant consequences for mental health. Here, we report the mental health sequelae of the COVID-19 pandemic in a UK cohort and examine modifiable and non-modifiable explanatory factors associated wi... Read More about Mental health in the UK during the COVID-19 pandemic: cross-sectional analyses from a community cohort study.

Earlier diagnosis of lung cancer in a randomised trial of an autoantibody blood test followed by imaging (2020)
Journal Article
Sullivan, F. M., Mair, F. S., Anderson, W., Armory, P., Briggs, A., Chew, C., …Schembri, S. (2021). Earlier diagnosis of lung cancer in a randomised trial of an autoantibody blood test followed by imaging. European Respiratory Journal, 57(1), Article 2000670. https://doi.org/10.1183/13993003.00670-2020

The EarlyCDT-Lung test is a high specificity blood-based autoantibody biomarker that could contribute to predicting lung cancer risk. Here we report on the results of a phase IV biomarker evaluation of whether using the EarlyCDT-Lung test and any sub... Read More about Earlier diagnosis of lung cancer in a randomised trial of an autoantibody blood test followed by imaging.

Effectiveness of psychosocial interventions for the prevention and treatment of foot ulcers in people with diabetes: a systematic review (2020)
Journal Article
Norman, G., Westby, M., Vedhara, K., Game, F., & Cullum, N. A. (2020). Effectiveness of psychosocial interventions for the prevention and treatment of foot ulcers in people with diabetes: a systematic review. Diabetic Medicine, 37(8), 1256-1265. https://doi.org/10.1111/dme.14326

Aims: To identify and synthesise the evidence for the effectiveness of psychosocial interventions to promote the healing, and/or reduce the occurrence of, foot ulceration in people with diabetes. Methods: In March 2019 we searched CENTRAL, Medline... Read More about Effectiveness of psychosocial interventions for the prevention and treatment of foot ulcers in people with diabetes: a systematic review.

Psychosocial and behavioural prognostic factors for diabetic foot ulcer development and healing: a systematic review (2020)
Journal Article
Westby, M., Norman, G., Vedhara, K., Game, F., & Cullum, N. A. (2020). Psychosocial and behavioural prognostic factors for diabetic foot ulcer development and healing: a systematic review. Diabetic Medicine, 37(8), 1244-1255. https://doi.org/10.1111/dme.14310

Aim: To investigate whether ulceration, amputation and healing of foot ulcers in people living with diabetes are associated with psychosocial and behavioural factors. Methods: We searched MEDLINE, Embase, PsychINFO, CINAHL and The Cochrane Library... Read More about Psychosocial and behavioural prognostic factors for diabetic foot ulcer development and healing: a systematic review.

External Validation of the ‘PHYT in Dementia’, a Theoretical Model Promoting Physical Activity in People with Dementia (2020)
Journal Article
Di Lorito, C., Bosco, A., Pollock, K., Harwood, R., das Nair, R., Logan, P., …van der Wardt, V. (2020). External Validation of the ‘PHYT in Dementia’, a Theoretical Model Promoting Physical Activity in People with Dementia. International Journal of Environmental Research and Public Health, 17(5), Article 1544. https://doi.org/10.3390/ijerph17051544

Physical activity is beneficial for people with dementia. We previously developed a theoretical model to explain behaviour change in physical activity in dementia (PHYT-in-dementia). This study aimed to externally validate the model. Validation occur... Read More about External Validation of the ‘PHYT in Dementia’, a Theoretical Model Promoting Physical Activity in People with Dementia.

The effectiveness and reporting standards of psychological interventions for improving short and long-term pain outcomes after total knee replacement: a systematic review (2019)
Journal Article
Whale, K., Wylde, V., Beswick, A. D., Rathbone, J., Vedhara, K., & Gooberman-Hill, R. (2019). The effectiveness and reporting standards of psychological interventions for improving short and long-term pain outcomes after total knee replacement: a systematic review. BMJ Open, 9(12), https://doi.org/10.1136/bmjopen-2019-029742

Objectives: To assess the effectiveness and reporting standards of psychological interventions for improving outcomes after total knee replacement (TKR). Design: The systematic review protocol was registered on the International Prospective Regist... Read More about The effectiveness and reporting standards of psychological interventions for improving short and long-term pain outcomes after total knee replacement: a systematic review.

Mood and influenza vaccination in older adults: A randomized controlled trial. (2019)
Journal Article
Ayling, K., Fairclough, L., Buchanan, H., Wetherell, M. A., & Vedhara, K. (2019). Mood and influenza vaccination in older adults: A randomized controlled trial. Health Psychology, 38(11), 984-996. https://doi.org/10.1037/hea0000786

Objective: Positive mood on the day of vaccination has been associated with subsequent antibody responses to the influenza vaccine in older adults. The primary aim of this trial was to examine whether a brief intervention was able to enhance positive... Read More about Mood and influenza vaccination in older adults: A randomized controlled trial..

Unconditional and conditional monetary incentives to increase response to mailed questionnaires: A randomized controlled study within a trial (SWAT) (2019)
Journal Article
Young, B., Bedford, L., das Nair, R., Gallant, S., Littleford, R., Robertson, J. F., …ECLS Study Team. (2020). Unconditional and conditional monetary incentives to increase response to mailed questionnaires: A randomized controlled study within a trial (SWAT). Journal of Evaluation in Clinical Practice, 26(3), 893-902. https://doi.org/10.1111/jep.13230

Rationale, aims, and objectives: High response rates to research questionnaires can help to ensure results are more representative of the population studied and provide increased statistical power, on which the study may have been predicated. Improvi... Read More about Unconditional and conditional monetary incentives to increase response to mailed questionnaires: A randomized controlled study within a trial (SWAT).

The relationship between patients’ illness beliefs and recovery after stroke (2018)
Journal Article
Aujla, N., Walker, M., Vedhara, K., & Sprigg, N. (2019). The relationship between patients’ illness beliefs and recovery after stroke. Psychology, Health and Medicine, 24(5), 551-558. https://doi.org/10.1080/13548506.2018.1557712

The Common Sense Model (CSM) is a useful framework for understanding mood and treatment adherence amongst survivors in the acute phase of stroke. CSM stroke studies have thus far focused on the single outcomes, mood and medication adherence, neglecti... Read More about The relationship between patients’ illness beliefs and recovery after stroke.

Keeping active: maintenance of physical activity after exercise programs for older adults (2018)
Journal Article
Kendrick, D., Orton, E., Lafond, N., Audsley, S., Maula, A., Morris, R., …Iliffe, S. (2018). Keeping active: maintenance of physical activity after exercise programs for older adults. Public Health, 164, 118-127. https://doi.org/10.1016/j.puhe.2018.08.003

Objectives: To explore factors associated with maintenance of moderate-to-vigorous physical activity (MVPA) in community-dwelling adults aged ?65 years after completing a 24-week exercise programme. Study design: Cohort study nested within a randomi... Read More about Keeping active: maintenance of physical activity after exercise programs for older adults.

Lung cancer screening: does pulmonary nodule detection affect a range of smoking behaviours? (2018)
Journal Article
Clark, M. E., Young, B., Bedford, L. E., Robertson, J. F., das Nair, R., Vedhara, K., …Kendrick, D. (2019). Lung cancer screening: does pulmonary nodule detection affect a range of smoking behaviours?. Journal of Public Health, 41(3), 600-608. https://doi.org/10.1093/pubmed/fdy158

Background Lung cancer screening can reduce lung cancer mortality by 20%. Screen-detected abnormalities may provide teachable moments for smoking cessation. This study assesses impact of pulmonary nodule detection on smoking behaviours within the fi... Read More about Lung cancer screening: does pulmonary nodule detection affect a range of smoking behaviours?.

Lung cancer CT screening: psychological responses in the presence and absence of pulmonary nodules (2018)
Journal Article
Clark, M. E., Bedford, L. E., Young, B., Robertson, J. F., das Nair, R., Vedhara, K., …Kendrick, D. (2018). Lung cancer CT screening: psychological responses in the presence and absence of pulmonary nodules. Lung Cancer, 124, 160-167. https://doi.org/10.1016/j.lungcan.2018.08.001

Objectives: To determine the psychological response (thoughts, perceptions and affect) to a diagnosis of pulmonary nodules following a novel antibody blood test and computed tomography (CT) scans within a UK population. Materials and methods: This... Read More about Lung cancer CT screening: psychological responses in the presence and absence of pulmonary nodules.

Measuring vaccine responses in the multiplex era (2018)
Book Chapter
Ayling, K., Vedhara, K., & Fairclough, L. (2018). Measuring vaccine responses in the multiplex era. In Q. Yan (Ed.), Psychoneuroimmunology: Methods and Protocols (327-340). (2nd). New York, USA: Springer Publishing Company. https://doi.org/10.1007/978-1-4939-7828-1_17

Vaccine studies in psychoneuroimmunology (PNI) provide an insight into biopsychosocial interactions and their role in infectious diseases. How to measure vaccine responses is therefore of critical importance for PNI researchers. In this chapter, trad... Read More about Measuring vaccine responses in the multiplex era.

Personality and gene expression: do individual differences exist in the leukocyte transcriptome? (2015)
Journal Article
Vedhara, K., Gill, S., Eldesouky, L., Campbell, B. K., Arevalo, J. M., Ma, J., & Cole, S. W. (2015). Personality and gene expression: do individual differences exist in the leukocyte transcriptome?. Psychoneuroendocrinology, 52, 72-82. doi:10.1016/j.psyneuen.2014.10.028

Background The temporal and situational stability of personality has led generations of researchers to hypothesize that personality may have enduring effects on health, but the biological mechanisms of such relationships remain poorly understood. In... Read More about Personality and gene expression: do individual differences exist in the leukocyte transcriptome?.