All Outputs (2)

Are DNA repair factors promising biomarkers for personalized therapy in gastric cancer? (2013)
Journal Article
Abdel-Fatah, T., Arora, A., Gorguc, I., Abbotts, R., Beebeejaun, S., Storr, S. J., …Madhusudan, S. (2013). Are DNA repair factors promising biomarkers for personalized therapy in gastric cancer?. Antioxidants and Redox Signaling, 18(18), https://doi.org/10.1089/ars.2012.4873

Chronic inflammation is a driving force for gastric carcinogenesis. Reactive oxygen species (ROS) generated during the inflammatory process generates DNA damage that is processed through the DNA repair pathways. In this study, we profiled key DNA rep... Read More about Are DNA repair factors promising biomarkers for personalized therapy in gastric cancer?.

Caspase-cleaved cytokeratin-18 and tumour regression in gastro-oesophageal adenocarcinomas treated with neoadjuvant chemotherapy (2012)
Journal Article
Fareed, K. R., Soomro, I. N., Hameed, K., Arora, A., Lobo, D. N., Parsons, S. L., & Madhusudan, S. (2012). Caspase-cleaved cytokeratin-18 and tumour regression in gastro-oesophageal adenocarcinomas treated with neoadjuvant chemotherapy. World Journal of Gastroenterology, 18(16), https://doi.org/10.3748/wjg.v18.i16.1915

AIM: To examine cytokeratin-18 (CK-18) and caspase-cleaved CK-18 expression in tumours and correlate with clinicopathological outcomes including tumour regression grade (TRG) response. METHODS: Formalin-fixed human gastro-oesophageal cancers were... Read More about Caspase-cleaved cytokeratin-18 and tumour regression in gastro-oesophageal adenocarcinomas treated with neoadjuvant chemotherapy.