All Outputs (3)

Cationic polymer mediated bacterial clustering: cell-adhesive properties of homo- and copolymers (2015)
Journal Article
Louzao, I., Sui, C., Winzer, K., Fernandez-Trillo, F., & Alexander, C. (2015). Cationic polymer mediated bacterial clustering: cell-adhesive properties of homo- and copolymers. European Journal of Pharmaceutics and Biopharmaceutics, 95, 47-62. https://doi.org/10.1016/j.ejpb.2015.05.026

New anti-infective materials are needed urgently as alternatives to conventional biocides. It has recently been established that polymer materials designed to bind to the surface of bacteria can induce the formation of cell clusters which enhance the... Read More about Cationic polymer mediated bacterial clustering: cell-adhesive properties of homo- and copolymers.

Integration of DNA into bacterial chromosomes from plasmids without a counter-selection marker (2012)
Journal Article
Heap, J. T., Ehsaan, M., Cooksley, C. M., Ng, Y., Cartman, S. T., Winzer, K., & Minton, N. P. (2012). Integration of DNA into bacterial chromosomes from plasmids without a counter-selection marker. Nucleic Acids Research, 40(8), Article 10. https://doi.org/10.1093/nar/gkr1321

Most bacteria can only be transformed with circular plasmids, so robust DNA integration methods for these rely upon selection of single-crossover clones followed by counter-selection of double-crossover clones. To overcome the limited availability of... Read More about Integration of DNA into bacterial chromosomes from plasmids without a counter-selection marker.

Density-dependent fitness benefits in quorum-sensing bacterial populations
Journal Article
Darch, S. E., West, S. A., Winzer, K., & Diggle, S. P. Density-dependent fitness benefits in quorum-sensing bacterial populations. Proceedings of the National Academy of Sciences, 109(21), https://doi.org/10.1073/pnas.1118131109

It has been argued that bacteria communicate using small diffusible signal molecules to coordinate, among other things, the production of factors that are secreted outside of the cells in a process known as quorum sensing (QS). The underlying assumpt... Read More about Density-dependent fitness benefits in quorum-sensing bacterial populations.