All Outputs (2)

Development of lipopolyplexes for gene delivery: a comparison of the effects of differing modes of targeting peptide display on the structure and transfection activities of lipopolyplexes (2018)
Journal Article
Bofinger, R., Zaw-Thin, M., Mitchell, N. J., Patrick, P. S., Stowe, C., Gomez-Ramirez, A., …Tabor, A. B. (2018). Development of lipopolyplexes for gene delivery: a comparison of the effects of differing modes of targeting peptide display on the structure and transfection activities of lipopolyplexes. Journal of Peptide Science, e3131. https://doi.org/10.1002/psc.3131

The design, synthesis and formulation of non‐viral gene delivery vectors is an area of renewed research interest. Amongst the most efficient non‐viral gene delivery systems are lipopolyplexes, in which cationic peptides are co‐formulated with plasmid... Read More about Development of lipopolyplexes for gene delivery: a comparison of the effects of differing modes of targeting peptide display on the structure and transfection activities of lipopolyplexes.

Construction of challenging proline–proline junctions via diselenide–selenoester ligation chemistry (2018)
Journal Article
Sayers, J., Karpati, P. M. T., Mitchell, N. J., Goldys, A. M., Kwong, S. M., Firth, N., …Payne, R. J. (2018). Construction of challenging proline–proline junctions via diselenide–selenoester ligation chemistry. Journal of the American Chemical Society, 140(41), 13327-13334. https://doi.org/10.1021/jacs.8b07877

Polyproline sequences are highly abundant in prokaryotic 10 and eukaryotic proteins, where they serve as key components of 11 secondary structure. To date, construction of the proline?proline motif 12 has not been possible owing to steric congestion... Read More about Construction of challenging proline–proline junctions via diselenide–selenoester ligation chemistry.