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Modulating the Biological Function of Protein by Tailoring the Adsorption Orientation on Nanoparticles (2020)
Other
Jain, A., Trindade, G., Hicks, J. M., Potts, J. C., Rahman, R., Hague, R., …Rawson, F. Modulating the Biological Function of Protein by Tailoring the Adsorption Orientation on Nanoparticles

Protein orientation in nanoparticle-protein conjugates plays a crucial role in binding to cell receptors and ultimately, defines their targeting efficiency. Therefore, understanding fundamental aspects of the role of protein orientation upon adsorpti... Read More about Modulating the Biological Function of Protein by Tailoring the Adsorption Orientation on Nanoparticles.

Enhancing singlet oxygen generation by self-assembly of a porphyrin entrapped in supramolecular fibres (2020)
Journal Article
Samperi, M., Limo, D., Amabilino, D. B., & Perez-Garc?a, L. (2020). Enhancing singlet oxygen generation by self-assembly of a porphyrin entrapped in supramolecular fibres. Cell Reports Physical Science, 1(3), https://doi.org/10.1016/jxcrp.2020.100030

Singlet oxygen (SO) is one of the reactive oxygen species that is effective in various uses, including performing chemical reactions, treating water impurities, and aiding in medicinal therapy. The generation of SO is often efficient in solution, alt... Read More about Enhancing singlet oxygen generation by self-assembly of a porphyrin entrapped in supramolecular fibres.

Quantification of energy of activation to supramolecular nanofibre formation reveals enthalpic and entropic effects and morphological consequence (2019)
Journal Article
Samperi, M., Perez-Garcia, L., & Amabilino, D. B. (2019). Quantification of energy of activation to supramolecular nanofibre formation reveals enthalpic and entropic effects and morphological consequence. Chemical Science, 2019(44), 10256-10266. https://doi.org/10.1039/c9sc03280k

We show a self-assembly process leading to fibres from a system that starts far from equilibrium because of fast solvent – anti-solvent mixing and analyse the activation energies associated with the aggregation. It is in some ways reminiscent of dive... Read More about Quantification of energy of activation to supramolecular nanofibre formation reveals enthalpic and entropic effects and morphological consequence.

Drug-Loaded Supramolecular Gels Prepared in a Microfluidic Platform: Distinctive Rheology and Delivery through Controlled Far-from-Equilibrium Mixing (2017)
Journal Article
Sathyanarayanan, G., Rodrigues, M., Limón, D., Rodriguez-Trujillo, R., Puigmartí-Luis, J., Pérez-García, L., & Amabilino, D. B. (2017). Drug-Loaded Supramolecular Gels Prepared in a Microfluidic Platform: Distinctive Rheology and Delivery through Controlled Far-from-Equilibrium Mixing. ACS Omega, 2(12), 8849-8858. https://doi.org/10.1021/acsomega.7b01800

It is shown here that controlled mixing of a gelator, drug, solvent, and antisolvent in a microfluidic channel leads to faster setting gels and more robust materials with longer release profiles than the physical gels of the same composition obtained... Read More about Drug-Loaded Supramolecular Gels Prepared in a Microfluidic Platform: Distinctive Rheology and Delivery through Controlled Far-from-Equilibrium Mixing.