All Outputs (25)

Oxidation of Monoterpenes to Form Diols and Triols: A Versatile Toolbox for Polymer Synthesis (2023)
Journal Article
Fowler, H. R., O'Brien, D. M., Keddie, D. J., Alexander, C., Irvine, D. J., Stockman, R. A., …Taresco, V. (2023). Oxidation of Monoterpenes to Form Diols and Triols: A Versatile Toolbox for Polymer Synthesis. Macromolecular Chemistry and Physics, 224(8), Article 2200446. https://doi.org/10.1002/macp.202200446

Polyols and polyacrylates have a wide range of applications in polymer synthesis as monomers, initiators, or building blocks in a variety of polymerization reaction types. With an ever-growing need to reduce the global dependency on fossil fuels, fin... Read More about Oxidation of Monoterpenes to Form Diols and Triols: A Versatile Toolbox for Polymer Synthesis.

Predictive Molecular Design and Structure–Property Validation of Novel Terpene-Based, Sustainably Sourced Bacterial Biofilm-Resistant Materials (2023)
Journal Article
Cuzzucoli Crucitti, V., Ilchev, A., Moore, J. C., Fowler, H. R., Dubern, J., Sanni, O., …Irvine, D. J. (2023). Predictive Molecular Design and Structure–Property Validation of Novel Terpene-Based, Sustainably Sourced Bacterial Biofilm-Resistant Materials. Biomacromolecules, https://doi.org/10.1021/acs.biomac.2c00721

Presented in this work is the use of a molecular descriptor, termed the α parameter, to aid in the design of a series of novel, terpene-based, and sustainable polymers that were resistant to biofilm formation by the model bacterial pathogen Pseudomon... Read More about Predictive Molecular Design and Structure–Property Validation of Novel Terpene-Based, Sustainably Sourced Bacterial Biofilm-Resistant Materials.

Sustainable ABA triblock methacrylate copolymers incorporating both high and low Tg terpene-derived monomers (2022)
Journal Article
Atkinson, R. L., Elsmore, M., Smith, S., Reynolds-Green, M., Topham, P. D., Toolan, D. T., …Howdle, S. M. (2022). Sustainable ABA triblock methacrylate copolymers incorporating both high and low Tg terpene-derived monomers. European Polymer Journal, 179, Article 11567. https://doi.org/10.1016/j.eurpolymj.2022.111567

We report the synthesis of novel terpene-based monomers: nopinyl acrylate and methacrylate, from naturally abundant β-pinene. A very high Tg value was observed for poly(nopinyl methacrylate) when synthesised by free radical polymerisation, and well-d... Read More about Sustainable ABA triblock methacrylate copolymers incorporating both high and low Tg terpene-derived monomers.

A self-crosslinking monomer, α-pinene methacrylate: understanding and exploiting hydrogen abstraction (2022)
Journal Article
Monaghan, O. R., Skowron, S. T., Moore, J. C., Pin-Nó, M., Kortsen, K., Atkinson, R. L., …Howdle, S. M. (2022). A self-crosslinking monomer, α-pinene methacrylate: understanding and exploiting hydrogen abstraction. Polymer Chemistry, 13(39), 5557-5567. https://doi.org/10.1039/d2py00878e

Crosslinking is a valuable route to creating new polymeric materials and normally involves introduction of a cross linker or some form of secondary processing. Here we report the discovery and analysis of a self-crosslinking sustainable terpene deriv... Read More about A self-crosslinking monomer, α-pinene methacrylate: understanding and exploiting hydrogen abstraction.

Sustainable terpene triblock copolymers with tuneable properties for pressure sensitive adhesive applications (2022)
Journal Article
Elsmore, M., Atkinson, R., Irvine, D., Howdle, S., & De Focatiis, D. (2022). Sustainable terpene triblock copolymers with tuneable properties for pressure sensitive adhesive applications. Polymer Testing, 109, Article 107530. https://doi.org/10.1016/j.polymertesting.2022.107530

A series of triblock copolymers in a hard-soft-hard block configuration with varying hard block α-pinene methacrylate content and molecular weight and butyl acrylate soft segment have been synthesised and investigated for viability in pressure sensit... Read More about Sustainable terpene triblock copolymers with tuneable properties for pressure sensitive adhesive applications.

Correction to “Bespoke 3D-Printed Polydrug Implants Created via Microstructural Control of Oligomers” (2022)
Journal Article
Ruiz-Cantu, L., Trindade, G. F., Taresco, V., Zhou, Z., He, Y., Burroughs, L., …Wildman, R. D. (2022). Correction to “Bespoke 3D-Printed Polydrug Implants Created via Microstructural Control of Oligomers”. ACS Applied Materials and Interfaces, 14(6), 8654. https://doi.org/10.1021/acsami.2c00035

The chemical structure of the drug trandolapril has been corrected in Figure 4c. The conclusions of the work have not been affected by this correction. (Figure present).

The influence of printing parameters on multi-material two-photon polymerisation based micro additive manufacturing (2021)
Journal Article
Hu, Q., Rance, G. A., Trindade, G. F., Pervan, D., Jiang, L., Foerster, A., …Wildman, R. D. (2022). The influence of printing parameters on multi-material two-photon polymerisation based micro additive manufacturing. Additive Manufacturing, 51, Article 102575. https://doi.org/10.1016/j.addma.2021.102575

Two-photon polymerisation (2PP) based additive manufacturing has emerged as a powerful technology to fabricate complex three-dimensional micro- and nanoscale architectures. However, a comprehensive understanding of the effect of printing parameters o... Read More about The influence of printing parameters on multi-material two-photon polymerisation based micro additive manufacturing.

Generation and Characterization of a Library of Novel Biologically Active Functional Surfactants (Surfmers) Using Combined High-Throughput Methods (2021)
Journal Article
Cuzzucoli Crucitti, V., Contreas, L., Taresco, V., Howard, S. C., Dundas, A. A., Limo, M. J., …Irvine, D. J. (2021). Generation and Characterization of a Library of Novel Biologically Active Functional Surfactants (Surfmers) Using Combined High-Throughput Methods. ACS Applied Materials and Interfaces, 13(36), 43290-43300. https://doi.org/10.1021/acsami.1c08662

We report the first successful combination of three distinct high-throughput techniques to deliver the accelerated design, synthesis, and property screening of a library of novel, bio-instructive, polymeric, comb-graft surfactants. These three-dimens... Read More about Generation and Characterization of a Library of Novel Biologically Active Functional Surfactants (Surfmers) Using Combined High-Throughput Methods.

Bespoke 3D-Printed Polydrug Implants Created via Microstructural Control of Oligomers (2021)
Journal Article
Ruiz-Cantu, L., Trindade, G. F., Taresco, V., Zhou, Z., He, Y., Burroughs, L., …Wildman, R. D. (2021). Bespoke 3D-Printed Polydrug Implants Created via Microstructural Control of Oligomers. ACS Applied Materials and Interfaces, 13(33), 38969-38978. https://doi.org/10.1021/acsami.1c07850

Controlling the microstructure of materials by means of phase separation is a versatile tool for optimizing material properties. Phase separation has been exploited to fabricate intricate microstructures in many fields including cell biology, tissue... Read More about Bespoke 3D-Printed Polydrug Implants Created via Microstructural Control of Oligomers.

Synthesis of model terpene-derived copolymers in supercritical carbon dioxide for cosmetic applications (2021)
Journal Article
Bennett, T. M., Portal, J., Jeanne-Rose, V., Taupin, S., Ilchev, A., Irvine, D. J., & Howdle, S. M. (2021). Synthesis of model terpene-derived copolymers in supercritical carbon dioxide for cosmetic applications. European Polymer Journal, 157, Article 110621. https://doi.org/10.1016/j.eurpolymj.2021.110621

There is currently a strong drive within the cosmetics industry to replace petroleum based solvents and polymers with renewable alternatives. Copolymers of 2-ethylhexyl acrylate (2EHA) and maleic anhydride (MA) are interesting model candidates to be... Read More about Synthesis of model terpene-derived copolymers in supercritical carbon dioxide for cosmetic applications.

RAFT polymerisation of renewable terpene (meth)acrylates and the convergent synthesis of methacrylate-acrylate-methacrylate triblock copolymers (2021)
Journal Article
Atkinson, R. L., Monaghan, O., Elsmore, M. T., Topham, P. D., Toolan, D. T. W., Derry, M. J., …Howdle, S. M. (2021). RAFT polymerisation of renewable terpene (meth)acrylates and the convergent synthesis of methacrylate-acrylate-methacrylate triblock copolymers. Polymer Chemistry, 12(21), 3177-3189. https://doi.org/10.1039/d1py00326g

Terpenes are ideal candidates for sustainable polymer feedstocks, due to their natural abundance and availability from existing waste streams. Previously, we have shown that a range of terpene(meth)acrylate monomers can be synthesised from the most c... Read More about RAFT polymerisation of renewable terpene (meth)acrylates and the convergent synthesis of methacrylate-acrylate-methacrylate triblock copolymers.

Synthesis of water-soluble surfactants using catalysed condensation polymerisation in green reaction media (2021)
Journal Article
Goddard, A. R., Apebende, E. A., Lentz, J. C., Carmichael, K., Taresco, V., Irvine, D. J., & Howdle, S. M. (2021). Synthesis of water-soluble surfactants using catalysed condensation polymerisation in green reaction media. Polymer Chemistry, https://doi.org/10.1039/d1py00415h

Sustainable and biobased surfactants are required for a wide range of everyday applications. Key drivers are cost, activity and efficiency of production. Polycondensation is an excellent route to build surfactant chains from bio-sourced monomers, but... Read More about Synthesis of water-soluble surfactants using catalysed condensation polymerisation in green reaction media.

A Click Chemistry Strategy for the Synthesis of Efficient Photoinitiators for Two?Photon Polymerization (2020)
Journal Article
Henning, I., Woodward, A. W., Rance, G. A., Paul, B. T., Wildman, R. D., Irvine, D. J., & Moore, J. C. (2020). A Click Chemistry Strategy for the Synthesis of Efficient Photoinitiators for Two?Photon Polymerization. Advanced Functional Materials, 30(50), Article 2006108. https://doi.org/10.1002/adfm.202006108

It is reported that efficient photoinitiators, suitable for two?photon polymerization, can be obtained using the copper catalyzed azide/alkyne cycloaddition reaction. This click chemistry strategy provides a modular approach to the assembly of photoi... Read More about A Click Chemistry Strategy for the Synthesis of Efficient Photoinitiators for Two?Photon Polymerization.

Synthesis of methacrylate-terminated block copolymers with reduced transesterification by controlled ring-opening polymerization (2018)
Journal Article
Ruiz-Cantu, L. A., Pearce, A. K., Burroughs, L., Bennett, T. M., Vasey, C. E., Wildman, R., …Taresco, V. (2019). Synthesis of methacrylate-terminated block copolymers with reduced transesterification by controlled ring-opening polymerization. Macromolecular Chemistry and Physics, 220(2), Article 1800459. https://doi.org/10.1002/macp.201800459

This work presents a robust method to achieve the synthesis of low molecular weight polyesters 26 via ring-opening polymerization (ROP) initiated by 2-hydroxyethyl-methacrylate (HEMA) 27 when using triazabicyclodecene (TBD) as catalyst. The effect th... Read More about Synthesis of methacrylate-terminated block copolymers with reduced transesterification by controlled ring-opening polymerization.

Synthesis and control of crosslinked poly(acrylic acid) based viscosity modifiers using dense phase carbon dioxide as a solvent (2018)
Journal Article
Alexander, W., Wickson, J., Duncan, J., Carmichael, K., Irvine, D., & Howdle, S. (2018). Synthesis and control of crosslinked poly(acrylic acid) based viscosity modifiers using dense phase carbon dioxide as a solvent. Journal of Supercritical Fluids, 139, 38-44. https://doi.org/10.1016/j.supflu.2018.05.003

We investigate the clean synthesis of a cross-linked poly(acrylic acid) viscosity modifier using supercritical CO2 to replace more hazardous volatile organic solvents that are typically used for this process. The polymers were analysed by aqueous swe... Read More about Synthesis and control of crosslinked poly(acrylic acid) based viscosity modifiers using dense phase carbon dioxide as a solvent.

Author Correction: Additive manufacture of complex 3D Au-containing nanocomposites by simultaneous two-photon polymerisation and photoreduction (2018)
Journal Article
Hu, Q., Sun, X., Parmenter, C. D. J., Fay, M. W., Smith, E. F., Rance, G. A., …Wildman, R. (2018). Author Correction: Additive manufacture of complex 3D Au-containing nanocomposites by simultaneous two-photon polymerisation and photoreduction. Scientific Reports, 8(1), Article 3512. https://doi.org/10.1038/s41598-018-21513-8

A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.

Additive manufacture of complex 3D Au-containing nanocomposites by simultaneous two-photon polymerisation and photoreduction (2017)
Journal Article
Parmenter, C. D. J., Hu, Q., Sun, X. Z., Parmenter, C. D., Fay, M. W., Smith, E. F., …Wildman, R. (2017). Additive manufacture of complex 3D Au-containing nanocomposites by simultaneous two-photon polymerisation and photoreduction. Scientific Reports, 7(1), Article 17150. https://doi.org/10.1038/s41598-017-17391-1

© 2017 The Author(s). The fabrication of complex three-dimensional gold-containing nanocomposite structures by simultaneous two-photon polymerisation and photoreduction is demonstrated. Increased salt delivers reduced feature sizes down to line width... Read More about Additive manufacture of complex 3D Au-containing nanocomposites by simultaneous two-photon polymerisation and photoreduction.

Amphiphilic block copolymers from a renewable ?-decalactone monomer: prediction and characterization of micellar core effects on drug encapsulation and release (2016)
Journal Article
Kakde, D., Taresco, V., Bansal, K. K., Magennis, E. P., Howdle, S. M., Mantovani, G., …Alexander, C. (in press). Amphiphilic block copolymers from a renewable Ɛ-decalactone monomer: prediction and characterization of micellar core effects on drug encapsulation and release. Journal of Materials Chemistry B, 44, https://doi.org/10.1039/C6TB01839D

Here we describe a methoxy poly(ethyleneglycol)-b-poly(ε-decalactone) (mPEG-b-PεDL) copolymer and investigate the potential of the copolymer as a vehicle for solubilisation and sustained release of indomethacin (IND). The indomethacin loading and rel... Read More about Amphiphilic block copolymers from a renewable ?-decalactone monomer: prediction and characterization of micellar core effects on drug encapsulation and release.

Application of Targeted Molecular and Material Property Optimization to Bacterial Attachment-Resistant (Meth)acrylate Polymers (2016)
Journal Article
Adlington, K., Nguyen, N. T., Eaves, E., Yang, J., Chang, C. Y., Li, J., …Irvine, D. J. (2016). Application of Targeted Molecular and Material Property Optimization to Bacterial Attachment-Resistant (Meth)acrylate Polymers. Biomacromolecules, 17(9), 2830-2838. https://doi.org/10.1021/acs.biomac.6b00615

© 2016 American Chemical Society. Developing medical devices that resist bacterial attachment and subsequent biofilm formation is highly desirable. In this paper, we report the optimization of the molecular structure and thus material properties of a... Read More about Application of Targeted Molecular and Material Property Optimization to Bacterial Attachment-Resistant (Meth)acrylate Polymers.

Synthesis, characterization and evaluation of in vitro toxicity in hepatocytes of linear polyesters with varied aromatic and aliphatic co-monomers (2016)
Journal Article
Kakde, D., Powell, L. G., Bansal, K. K., Howdle, S., Irvine, D., Mantovani, G., …Alexander, C. (2016). Synthesis, characterization and evaluation of in vitro toxicity in hepatocytes of linear polyesters with varied aromatic and aliphatic co-monomers. Journal of Controlled Release, 244(B), https://doi.org/10.1016/j.jconrel.2016.08.003

Polyesters are extensively used in drug delivery because of their controllable biodegradation properties and perceived favorable cytocompatibility. However, new ester-based materials are continually being sought which can be produced from readily acc... Read More about Synthesis, characterization and evaluation of in vitro toxicity in hepatocytes of linear polyesters with varied aromatic and aliphatic co-monomers.