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Altered connectivity of the right anterior insula drives the pain connectome changes in chronic knee osteoarthritis (2018)
Journal Article
Cottam, W. J., Iwabuchi, S. J., Drabek, M. M., Reckziegel, D., & Auer, D. P. (2018). Altered connectivity of the right anterior insula drives the pain connectome changes in chronic knee osteoarthritis. PAIN, 159(5), doi:10.1097/j.pain.0000000000001209

Resting-state functional connectivity (FC) has proven a powerful approach to understand the neural underpinnings of chronic pain, reporting altered connectivity in three main networks: the default mode (DMN), central executive (CEN), and the salience... Read More

Coordinate based random effect size meta-analysis of neuroimaging studies (2017)
Journal Article
Tench, C. R., Tanasescu, R., Constantinescu, C. S., Auer, D. P., & Cottam, W. J. (in press). Coordinate based random effect size meta-analysis of neuroimaging studies. NeuroImage, 153, doi:10.1016/j.neuroimage.2017.04.002. ISSN 1053-8119

Low power in neuroimaging studies can make them difficult to interpret, and Coordinate based meta-analysis (CBMA) may go some way to mitigating this issue. CBMA has been used in many analyses to detect where published functional MRI or voxel-based mo... Read More

Associations of limbic-affective brain activity and severity of ongoing chronic arthritis pain are explained by trait anxiety (2016)
Journal Article
Cottam, W. J., Condon, L., Alshuft, H., Reckziegel, D., & Auer, D. P. (in press). Associations of limbic-affective brain activity and severity of ongoing chronic arthritis pain are explained by trait anxiety. NeuroImage: Clinical, 12, doi:10.1016/j.nicl.2016.06.022. ISSN 2213-1582

Functional magnetic resonance imaging studies (fMRI) have transformed our understanding of central processing of evoked pain but the typically used block and event-related designs are not best suited to the study of ongoing pain. Here we used arteria... Read More