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All Outputs (51)

Exploring community pharmacy and general practice views on primary care communication and pathways to access antibiotics in England (2025)
Journal Article
Lee, M. X., Hayes, C., Ashiru-Oredope, D., Thornley, T., Howard, P., Saei, A., Eastwood, L., & Lecky, D. M. (2025). Exploring community pharmacy and general practice views on primary care communication and pathways to access antibiotics in England. Journal of Antimicrobial Chemotherapy, 80(7), 1828–1836. https://doi.org/10.1093/jac/dkaf135

Background

With most antimicrobials in England being prescribed in primary care, collaboration on antimicrobial stewardship (AMS) between general practitioners (GPs) and community pharmacists (CPs) is important. Previous research identified barrie... Read More about Exploring community pharmacy and general practice views on primary care communication and pathways to access antibiotics in England.

A mixed methods protocol for an impact and implementation evaluation of the Pharmacy First Services for management of common conditions in England (2025)
Journal Article
Glover, R. E., Lalani, M., Sonnex, K., Allen, T., Anderson, C., Ashiru-Oredope, D., Avery, A., Coupland, C., Elliott, R., Goulding, J., Higgins, H., Johnson, S., Mackenna, B., Muller-Pebody, B., O’Neill, S., Pacho, A., Taylor, A., Thornley, T., & Mays, N. (2025). A mixed methods protocol for an impact and implementation evaluation of the Pharmacy First Services for management of common conditions in England. International Journal of Pharmacy Practice, 33(2), 152-161. https://doi.org/10.1093/ijpp/riaf004

Objectives
In response to high levels of demand for primary medical services in England, characterized by longer appointment waiting times and delayed referrals, the Government developed its National Health Service (NHS) Primary Care Recovery Plan.... Read More about A mixed methods protocol for an impact and implementation evaluation of the Pharmacy First Services for management of common conditions in England.

Difficulties with prescribed opioids: a cross-sectional survey of primary care patients in England, United Kingdom (2025)
Journal Article
Wilson, L. E., Knaggs, R. D., Avery, A. J., Thornley, T., Moss, J., Baamer, R. M., & Boyd, M. J. (2025). Difficulties with prescribed opioids: a cross-sectional survey of primary care patients in England, United Kingdom. PAIN Reports, 10(2), Article e1246. https://doi.org/10.1097/PR9.0000000000001246

Introduction:
Knowledge of the potential for harm and adverse effects from long-term opioid medicines has led to reduced prescribing in recent years. However, the number of patients receiving opioid prescriptions from primary care in England remains... Read More about Difficulties with prescribed opioids: a cross-sectional survey of primary care patients in England, United Kingdom.

Key stakeholder's attitudes towards the professional accountabilities and responsibilities of newly qualified Pharmacist Independent Prescribers (IPs) in England and enablers to implementation at scale? (2024)
Journal Article
Warner, B., Thornley, T., Anderson, C., & Avery, A. (2025). Key stakeholder's attitudes towards the professional accountabilities and responsibilities of newly qualified Pharmacist Independent Prescribers (IPs) in England and enablers to implementation at scale?. Health Policy, 152, Article 105223. https://doi.org/10.1016/j.healthpol.2024.105223

Background
Independent prescribing is set to expand amongst community pharmacists in England in the next few years. This study aims to explore the different accountabilities and responsibilities associated with independent prescribing compared to mo... Read More about Key stakeholder's attitudes towards the professional accountabilities and responsibilities of newly qualified Pharmacist Independent Prescribers (IPs) in England and enablers to implementation at scale?.

Assessing the Performance of Machine Learning Methods Trained on Public Health Observational Data: A Case Study From COVID-19 (2024)
Journal Article
Pigoli, D., Baker, K., Budd, J., Butler, L., Coppock, H., Egglestone, S., Gilmour, S., Holmes, C., Hurley, D., Jersakova, R., Kiskin, I., Koutra, V., Mellor, J., Nicholson, G., Packham, J., Patel, S., Payne, R., Roberts, S. J., Schuller, B. W., Tendero-Cañadas, A., …Titcomb, A. (2024). Assessing the Performance of Machine Learning Methods Trained on Public Health Observational Data: A Case Study From COVID-19. Statistics in Medicine, 43(25), 4861-4871. https://doi.org/10.1002/sim.10211

From early in the coronavirus disease 2019 (COVID-19) pandemic, there was interest in using machine learning methods to predict COVID-19 infection status based on vocal audio signals, for example, cough recordings. However, early studies had limitati... Read More about Assessing the Performance of Machine Learning Methods Trained on Public Health Observational Data: A Case Study From COVID-19.

Pilot and quantitative evaluation of the TARGET acne toolkit by UK pharmacy professionals working in general practice (2024)
Journal Article
Sonnex, K., Thornley, T., Fleming, N., Lakha, A., Lecky, D. M., Pillay, I., Patel, S., Anderson, C., Boyd, M., Ashiru-Oredope, D., & Boyd, M. (2024). Pilot and quantitative evaluation of the TARGET acne toolkit by UK pharmacy professionals working in general practice. BMJ Open, 14(7), Article e081641. https://doi.org/10.1136/bmjopen-2023-081641

Background Acne vulgaris (acne) is a common skin condition sometimes needing topical or oral antibiotic treatment. Pharmacists and pharmacy technicians (together known as pharmacy professionals) working in general practice are well placed to ensure t... Read More about Pilot and quantitative evaluation of the TARGET acne toolkit by UK pharmacy professionals working in general practice.

A large-scale and PCR-referenced vocal audio dataset for COVID-19 (2024)
Journal Article
Budd, J., Baker, K., Karoune, E., Coppock, H., Patel, S., Payne, R., Tendero Cañadas, A., Titcomb, A., Hurley, D., Egglestone, S., Butler, L., Mellor, J., Nicholson, G., Kiskin, I., Koutra, V., Jersakova, R., McKendry, R., Diggle, P., Richardson, S., Schuller, B., …Holmes, C. (2024). A large-scale and PCR-referenced vocal audio dataset for COVID-19. Scientific Data, 11, Article 700. https://doi.org/10.1038/s41597-024-03492-w

The UK COVID-19 Vocal Audio Dataset is designed for the training and evaluation of machine learning models that classify SARS-CoV-2 infection status or associated respiratory symptoms using vocal audio. The UK Health Security Agency recruited volunta... Read More about A large-scale and PCR-referenced vocal audio dataset for COVID-19.

Estimating the prevalence of potential and actionable drug‐gene interactions in Irish primary care: A cross‐sectional study (2024)
Journal Article
Johnson, L., Youssef, E., O'Shea, J., Thornley, T., Gallagher, J., Ledwidge, M., & Ryan, C. (2024). Estimating the prevalence of potential and actionable drug‐gene interactions in Irish primary care: A cross‐sectional study. British Journal of Clinical Pharmacology, 90(9), 2280-2298. https://doi.org/10.1111/bcp.16122

Aims
Pharmacogenetics (PGx) is increasingly recognized as a strategy for medicines optimisation and prevention of adverse drug reactions. According to guidelines produced by the Clinical Pharmacogenetics Implementation Consortium (CPIC) and the Dutc... Read More about Estimating the prevalence of potential and actionable drug‐gene interactions in Irish primary care: A cross‐sectional study.

Audio-based AI classifiers show no evidence of improved COVID-19 screening over simple symptoms checkers (2024)
Journal Article
Coppock, H., Nicholson, G., Kiskin, I., Koutra, V., Baker, K., Budd, J., Payne, R., Karoune, E., Hurley, D., Titcomb, A., Egglestone, S., Tendero Cañadas, A., Butler, L., Jersakova, R., Mellor, J., Patel, S., Thornley, T., Diggle, P., Richardson, S., Packham, J., …Holmes, C. (2024). Audio-based AI classifiers show no evidence of improved COVID-19 screening over simple symptoms checkers. Nature Machine Intelligence, 6, 229-242. https://doi.org/10.1038/s42256-023-00773-8

Recent work has reported that respiratory audio-trained AI classifiers can accurately predict SARS-CoV-2 infection status. However, it has not yet been determined whether such model performance is driven by latent audio biomarkers with true causal li... Read More about Audio-based AI classifiers show no evidence of improved COVID-19 screening over simple symptoms checkers.

Evaluating the role of primary care pharmacy technicians in antimicrobial stewardship (AMS) and acne management using TARGET resources (2024)
Journal Article
Lakha, A., Fleming, N., Sonnex, K., Thornley, T., Anderson, C., Hand, . K., & Ashiru-Oredope, D. (2024). Evaluating the role of primary care pharmacy technicians in antimicrobial stewardship (AMS) and acne management using TARGET resources. JAC-Antimicrobial Resistance, 6(1), Article dlae011. https://doi.org/10.1093/jacamr/dlae011

Background: Inappropriate antibiotic prescribing is accelerating antimicrobial resistance (AMR) (Antibiotic resistant infections and associated deaths increase https://www.gov.uk/government/news/antibiotic-resistant-infections-And-Associated-deaths-i... Read More about Evaluating the role of primary care pharmacy technicians in antimicrobial stewardship (AMS) and acne management using TARGET resources.

A CROSS-SECTIONAL STUDY TO EXPLORE THE PRESCRIBING OF DRUGS WITH POTENTIAL DRUG GENE INTERACTIONS IN IRISH PRIMARY CARE (2023)
Presentation / Conference Contribution
Johnson, L., Youssef, E., O'Shea, J., Ledwidge, M., Thornley, T., Gallagher, J., & Ryan, C. (2023, October). A CROSS-SECTIONAL STUDY TO EXPLORE THE PRESCRIBING OF DRUGS WITH POTENTIAL DRUG GENE INTERACTIONS IN IRISH PRIMARY CARE. Poster presented at ESCP Aberdeen Symposium 2023: Innovations in Clinical Pharmacy Practice, Education and Research, Aberdeen, UK

Background and Objective: Pharmacogenetics (PGx) is being increasingly recognised as a strategy for medicines optimisation and prevention of adverse drug reactions. According to guidelines produced by the Clinical Pharmacogenetics Implementation Cons... Read More about A CROSS-SECTIONAL STUDY TO EXPLORE THE PRESCRIBING OF DRUGS WITH POTENTIAL DRUG GENE INTERACTIONS IN IRISH PRIMARY CARE.

Perceived current and future roles of UK-based community pharmacy professionals in the long-term management of acne (2023)
Journal Article
Sonnex, K., Thornley, T., Fleming, N., Lakha, A., Lecky, D. M., Pillay, I., Patel, S., Anderson, C., Boyd, M., & Ashiru-Oredope, D. (2023). Perceived current and future roles of UK-based community pharmacy professionals in the long-term management of acne. Exploratory Research in Clinical and Social Pharmacy, 11, Article 100310. https://doi.org/10.1016/j.rcsop.2023.100310

Introduction: Acne is a common skin condition treated in community pharmacy but moderate to severe cases may need referral to general practice for treatment that may include topical or oral antimicrobial treatments. Pharmacy teams working in the comm... Read More about Perceived current and future roles of UK-based community pharmacy professionals in the long-term management of acne.

Engaging trainee pharmacists in schools’ outreach and science communication through the UKHSA ‘Antibiotic Guardian Schools Ambassadors' initiative (2023)
Presentation / Conference Contribution
Thornley, T., Miah, T., Charlesworth, J., Gilham, E., Ayeni, A., Solanki, K., Dunne, R., & Ashiru-Oredope, D. (2023, May). Engaging trainee pharmacists in schools’ outreach and science communication through the UKHSA ‘Antibiotic Guardian Schools Ambassadors' initiative. Presented at Clinical Pharmacy Congress 2023, London, UK

Antimicrobial resistance (AMR) is one of the biggest threats facing humanity today. AMR and stewardship are important topics for early career pharmacists to navigate. In 2022, UK Health Security Agency (UKHSA) and Boots UK collaborated to incorporate... Read More about Engaging trainee pharmacists in schools’ outreach and science communication through the UKHSA ‘Antibiotic Guardian Schools Ambassadors' initiative.

Assessing the impact of the ‘Antibiotic Guardian Schools Ambassadors' initiative on trainee pharmacist learning and development (2023)
Presentation / Conference Contribution
Thornley, T., Miah, T., Charlesworth, J., Gilham, E., Ayeni, A., Solanki, K., Dunne, R., & Ashiru-Oredope, D. (2023, May). Assessing the impact of the ‘Antibiotic Guardian Schools Ambassadors' initiative on trainee pharmacist learning and development. Poster presented at Clinical Pharmacy Congress, London, UK

Background and introduction (100)
The World Health Organisation has declared that antimicrobial resistance (AMR) is one of the top 10 global public health threats facing humanity today. It is imperative that AMR and antimicrobial stewardship are rec... Read More about Assessing the impact of the ‘Antibiotic Guardian Schools Ambassadors' initiative on trainee pharmacist learning and development.

What affected UK adults’ adherence to medicines during the COVID-19 pandemic? Cross-sectional survey in a representative sample of people with long-term conditions (2023)
Journal Article
Penner, L. S., Armitage, C. J., Thornley, T., Whelan, P., Chuter, A., Allen, T., & Elliott, R. A. (2024). What affected UK adults’ adherence to medicines during the COVID-19 pandemic? Cross-sectional survey in a representative sample of people with long-term conditions. Journal of Public Health, 32(2), 325-338. https://doi.org/10.1007/s10389-022-01813-0

Aim
Medicines non-adherence is associated with poorer outcomes and higher costs. COVID-19 affected access to healthcare, with increased reliance on remote methods, including medicines supply. This study aimed to identify what affected people’s adher... Read More about What affected UK adults’ adherence to medicines during the COVID-19 pandemic? Cross-sectional survey in a representative sample of people with long-term conditions.

Mixed-Method Evaluation of a Community Pharmacy Antimicrobial Stewardship Intervention (PAMSI) (2022)
Journal Article
Hayes, C. V., Lecky, D. M., Pursey, F., Thomas, A., Ashiru-Oredope, D., Saei, A., Thornley, T., Howard, P., Dickinson, A., Ingram, C., Allison, R., & McNulty, C. A. M. (2022). Mixed-Method Evaluation of a Community Pharmacy Antimicrobial Stewardship Intervention (PAMSI). Healthcare, 10(7), Article 1288. https://doi.org/10.3390/healthcare10071288

The community pharmacy antimicrobial stewardship intervention (PAMSI) is multi-faceted and underpinned by behavioural science, consisting of the TARGET Antibiotic Checklist, staff e-Learning, and patient-facing materials. This mixed-method study eval... Read More about Mixed-Method Evaluation of a Community Pharmacy Antimicrobial Stewardship Intervention (PAMSI).

Pharmacogenetics: optimising prescribing in primary care (2022)
Journal Article
Youssef, E., Thornley, T., Guchelaar, H., & Wright, D. J. (2022). Pharmacogenetics: optimising prescribing in primary care. Prescriber, 33(5), 10-13. https://doi.org/10.1002/psb.1982

Pharmacogenetic (PGx) testing to personalise prescribing of certain medicines can improve patient outcomes and reduce adverse drug reactions. This article summarises the key findings of the PGx Impact study, designed to estimate the impact of pre‐emp... Read More about Pharmacogenetics: optimising prescribing in primary care.

Implementation of a Pharmacogenomic Testing Service through Community Pharmacy in the Netherlands: Results from an Early Service Evaluation (2021)
Journal Article
Thornley, T., Esquivel, B., Wright, D. J., van den Dop, H., Kirkdale, C. L., & Youssef, E. (2021). Implementation of a Pharmacogenomic Testing Service through Community Pharmacy in the Netherlands: Results from an Early Service Evaluation. Pharmacy, 9(1), Article 38. https://doi.org/10.3390/pharmacy9010038

Community pharmacy services have evolved to include medical and pharmaceutical interventions alongside dispensing. While established pharmacogenomic (PGx) testing is available throughout the Netherlands, this is primarily based in hospital environmen... Read More about Implementation of a Pharmacogenomic Testing Service through Community Pharmacy in the Netherlands: Results from an Early Service Evaluation.