Temozolomide analog PMX 465 downregulates MGMT expression in HCT116 colorectal carcinoma cells
(2018)
Journal Article
Yang, Z., Wei, D., Liu, F., Liu, J., Wu, X., Stevens, M. F. G., …Zhang, J. (in press). Temozolomide analog PMX 465 downregulates MGMT expression in HCT116 colorectal carcinoma cells. Journal of Cellular Biochemistry, https://doi.org/10.1002/jcb.26674
The efficacy of temozolomide (TMZ) treatment for cancers is currently limited by inherent or the development of resistance, particularly, but not exclusively, due to the expression of the DNA repair enzyme O6-methylguanine-DNA methyltransferase (MGMT... Read More about Temozolomide analog PMX 465 downregulates MGMT expression in HCT116 colorectal carcinoma cells.