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Frequency- and state-dependent effects of hippocampal neural disinhibition on hippocampal local field potential oscillations in anaesthetised rats (2019)
Other
Gwilt, M., Bauer, M., & Bast, T. (2019). Frequency- and state-dependent effects of hippocampal neural disinhibition on hippocampal local field potential oscillations in anaesthetised rats

Reduced inhibitory GABA function, so-called neural disinhibition, has been implicated in cognitive disorders, including schizophrenia and age-related cognitive decline. We previously showed in rats that hippocampal disinhibition by local microinfusio... Read More about Frequency- and state-dependent effects of hippocampal neural disinhibition on hippocampal local field potential oscillations in anaesthetised rats.

Quand le cerveau en fait trop (2019)
Journal Article
Bast, T. (2019). Quand le cerveau en fait trop. Cerveau & Psycho, 116, 16-22

« Mais où ai-je garé ma voiture ? Pourquoi suis-je étourdi ce matin ? Mon cerveau n'est pas réveillé ! » Longtemps, on a cru que des troubles cognitifs et de nombreuses maladies mentales étaient dus à une activité cérébrale insuffisante. En fait, c'... Read More about Quand le cerveau en fait trop.

Weniger ist manchmal mehr! (2019)
Journal Article
Bast, T. (2019). Weniger ist manchmal mehr!. Gehirn und Geist, 8/2019, 46-51

HIRNFORSCHUNG NEURONALE HEMMUNG Lange Zeit dachten Forscher, dass viele neurologische und psychiatrische Erkrankungen auf einer zu geringen Hirnaktivität beruhen. Doch häufig ist genau das Gegenteil der Fall.

Dopamine D1-like receptors in the dorsomedial prefrontal cortex regulate contextual fear conditioning (2019)
Journal Article
Stubbendorff, C., Hale, E., Cassaday, H. J., Bast, T., & Stevenson, C. W. (2019). Dopamine D1-like receptors in the dorsomedial prefrontal cortex regulate contextual fear conditioning. Psychopharmacology, 236(6), 1771-1782. https://doi.org/10.1007/s00213-018-5162-7

Rationale Dopamine D1 receptor (D1R) signalling is involved in contextual fear conditioning. The D1R antagonist SCH23390 impairs the acquisition of contextual fear when administered systemically or infused locally into the dorsal hippocampus or ba... Read More about Dopamine D1-like receptors in the dorsomedial prefrontal cortex regulate contextual fear conditioning.