Research Repository

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Recombinant viruses for cancer therapy (2018)
Journal Article
Chulpanova, D. S., Solovyeva, V. V., Kitaeva, K. V., Dunham, S. P., Khaiboullina, S. F., & Rizvanov, A. A. (2018). Recombinant viruses for cancer therapy. Biomedicines, 6(4), 1-14. doi:10.3390/biomedicines6040094

Recombinant viruses are novel therapeutic agents that can be utilized for treatment of various diseases, including cancers. Recombinant viruses can be engineered to express foreign transgenes and have a broad tropism allowing gene expression in a wid... Read More

Longitudinal study of Asian elephants, Elephas maximus, indicates intermittent shedding of elephant endotheliotropic herpesvirus 1 during pregnancy (2015)
Journal Article
herpesvirus 1 during pregnancy. Veterinary Record Open, 2(1), doi:10.1136/vetreco-2014-000088. ISSN 2052-6113

Introduction: EEHV-1 is a viral infection of elephants that has been associated with a fatal haemorrhagic syndrome in Asian elephants. Previous studies have suggested that pregnant animals may shed more virus than non-pregnant animals. Methods: This... Read More

DNA microarray global gene expression analysis of influenza virus-infected chicken and duck cells (2015)
Journal Article
Kuchipudi, S., Chang, K., & Dunham, S. (2015). DNA microarray global gene expression analysis of influenza virus-infected chicken and duck cells. Genomics Data, 4, 60-64. doi:10.1016/j.gdata.2015.03.004

The data described in this article pertain to the article by Kuchipudi et al. (2014) titled “Highly Pathogenic Avian Influenza Virus Infection in Chickens But Not Ducks Is Associated with Elevated Host Immune and Pro-inflammatory Responses” [1]. Whil... Read More

Identification of morphological differences between avian influenza A viruses grown in chicken and duck cells (2015)
Journal Article
Al-Mubarak, F., Daly, J. M., Christie, D., Fountain, D., & Dunham, S. P. (2015). Identification of morphological differences between avian influenza A viruses grown in chicken and duck cells. Virus Research, 199, doi:10.1016/j.virusres.2015.01.005. ISSN 0168-1702

Although wild ducks are considered to be the major reservoirs for most influenza A virus subtypes, they are typically resistant to the effects of the infection. In contrast, certain influenza viruses may be highly pathogenic in other avian hosts such... Read More

A consensus approach to vertebrate de novo transcriptome assembly from RNA-seq data: assembly of the duck (Anas platyrhynchos) transcriptome (2014)
Journal Article
Moreton, J., Dunham, S. P., & Emes, R. D. (2014). A consensus approach to vertebrate de novo transcriptome assembly from RNA-seq data: assembly of the duck (Anas platyrhynchos) transcriptome. Frontiers in Genetics, 5, doi:10.3389/fgene.2014.00190. ISSN 1664-8021

For vertebrate organisms where a reference genome is not available, de novo transcriptome assembly enables a cost effective insight into the identification of tissue specific or differentially expressed genes and variation of the coding part of the g... Read More

The challenge of Schmallenberg virus emergence in Europe (2012)
Journal Article
Tarlinton, R. E., Daly, J. M., Dunham, S. P., & Kydd, J. M. (2012). The challenge of Schmallenberg virus emergence in Europe. Veterinary Journal, 194(1), doi:10.1016/j.tvjl.2012.08.017. ISSN 1090-0233

The large-scale outbreak of disease across Northern Europe caused by a new orthobunyavirus known as Schmallenberg virus has caused considerable disruption to lambing and calving. Although advances in technology and collaboration between veterinary... Read More