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All Outputs (31)

Association between quadriceps tendon elasticity and neuromuscular control in individuals with knee osteoarthritis. (2023)
Journal Article
Dickson, D. M., Smith, S. L., & Hendry, G. J. (2024). Association between quadriceps tendon elasticity and neuromuscular control in individuals with knee osteoarthritis. Clinical Biomechanics, 111, Article 106159. https://doi.org/10.1016/j.clinbiomech.2023.106159

Background: Knee osteoarthritis is a complex condition with established risk factors such as female sex, increasing age and body mass index, reduced quadriceps muscle strength and knee injury. Despite known associated risks, the role and behaviour of... Read More about Association between quadriceps tendon elasticity and neuromuscular control in individuals with knee osteoarthritis..

Associations of Muscle Strength with Central Aspects of Pain: Data from the Knee Pain and Related Health in the Community (KPIC) Cohort (2023)
Journal Article
McWilliams, D. F., Yue, B., Smith, S. L., Stocks, J., Doherty, M., Valdes, A. M., …Walsh, D. A. (2023). Associations of Muscle Strength with Central Aspects of Pain: Data from the Knee Pain and Related Health in the Community (KPIC) Cohort. Journal of Personalized Medicine, 13(10), Article 1450. https://doi.org/10.3390/jpm13101450

Knee pain is associated with lower muscle strength, and both contribute to disability. Peripheral and central neurological mechanisms contribute to OA pain. Understanding the relative contributions of pain mechanisms to muscle strength might help fut... Read More about Associations of Muscle Strength with Central Aspects of Pain: Data from the Knee Pain and Related Health in the Community (KPIC) Cohort.

P073 Comparative effectiveness of different exercise interventions on central sensitisation indices in humans: A systematic review and network meta-analysis (2023)
Journal Article
Abd Elkhabir, A. A., McWilliams, D. F., Smith, S., Chaplin, W., Salimian, M., Georgopoulos, V., …Walsh, D. A. (2023). P073 Comparative effectiveness of different exercise interventions on central sensitisation indices in humans: A systematic review and network meta-analysis. Rheumatology, 62(Supplement 2), Article kead104.114. https://doi.org/10.1093/rheumatology/kead104.114

Background/Aims Exercise has shown a promising effect in reducing central sensitisation (CS), but it is unknown which exercise type is the most effective. This review aimed to rank and compare the effectiveness of different exercise interventions o... Read More about P073 Comparative effectiveness of different exercise interventions on central sensitisation indices in humans: A systematic review and network meta-analysis.

Harmonising knee pain patient-reported outcomes: a systematic literature review and meta-analysis of Patient Acceptable Symptom State (PASS) and individual participant data (IPD) (2022)
Journal Article
Georgopoulos, V., Smith, S., McWilliams, D. F., Steultjens, M. P. M., Williams, A., Price, A., …Walsh, D. A. (2023). Harmonising knee pain patient-reported outcomes: a systematic literature review and meta-analysis of Patient Acceptable Symptom State (PASS) and individual participant data (IPD). Osteoarthritis and Cartilage, 31(1), 83-95. https://doi.org/10.1016/j.joca.2022.08.011

Objective: In order to facilitate data pooling between studies, we explored harmonisation of patient-reported outcome measures (PROMs) in people with knee pain due to osteoarthritis or knee trauma, using the Patient Acceptable Symptom State scores (P... Read More about Harmonising knee pain patient-reported outcomes: a systematic literature review and meta-analysis of Patient Acceptable Symptom State (PASS) and individual participant data (IPD).

Biomarkers associated with lower limb muscle function in individuals with sarcopenia: a systematic review (2022)
Journal Article
Jones, R., Paul, L., Steultjens, M., & Smith, S. L. (2022). Biomarkers associated with lower limb muscle function in individuals with sarcopenia: a systematic review. Journal of Cachexia, Sarcopenia and Muscle, 13(6), 2791-2806. https://doi.org/10.1002/jcsm.13064

Lower limb muscle dysfunction is a key driver for impaired physical capacity and frailty status, both characteristics of sarcopenia. Sarcopenia is the key pathway between frailty and disability. Identifying biological markers for early diagnosis, tre... Read More about Biomarkers associated with lower limb muscle function in individuals with sarcopenia: a systematic review.

Strain sonoelastography in asymptomatic individuals and individuals with knee osteoarthritis: an evaluation of quadriceps and patellar tendon (2022)
Journal Article
Dickson, D. M., Smith, S. L., & Hendry, G. J. (2022). Strain sonoelastography in asymptomatic individuals and individuals with knee osteoarthritis: an evaluation of quadriceps and patellar tendon. Rheumatology International, 42(12), 2241-2251. https://doi.org/10.1007/s00296-022-05184-3

An advanced ultrasound imaging technique, sonoelastography (SE) is used to evaluate tissue elasticity. To determine SE potential to detect pathological-related changes, and characteristics related to tendon pathology we aimed to (1) compare quadricep... Read More about Strain sonoelastography in asymptomatic individuals and individuals with knee osteoarthritis: an evaluation of quadriceps and patellar tendon.

An observational study of centrally facilitated pain in individuals with chronic low back pain (2022)
Journal Article
Georgopoulos, V., Akin-Akinyosoye, K., Smith, S., McWilliams, D. F., Hendrick, P., & Walsh, D. A. (2022). An observational study of centrally facilitated pain in individuals with chronic low back pain. PAIN Reports, 7(3), Article e1003. https://doi.org/10.1097/PR9.0000000000001003

Central pain facilitation can hinder recovery in people with chronic low back pain (CLBP). The aim of this observational study was to investigate whether indices of centrally facilitated pain are associated with pain outcomes in a hospital-based coho... Read More about An observational study of centrally facilitated pain in individuals with chronic low back pain.

Central pain mechanisms predict physical inactivity at 1-year in individuals with knee pain (2022)
Journal Article
Habib, M., Smith, S., Chaplin, W., Millar, B., McWilliams, D., & Walsh, D. (2022). Central pain mechanisms predict physical inactivity at 1-year in individuals with knee pain. Osteoarthritis and Cartilage, 30(Sup 1), S379. https://doi.org/10.1016/j.joca.2022.02.511

Purpose: Pain is the primary clinical manifestation in individuals with osteoarthritis (OA). It is an unpleasant and distressing experience, particularly during weight-bearing activities, inhibiting activity, and reducing quality of life. Two groups... Read More about Central pain mechanisms predict physical inactivity at 1-year in individuals with knee pain.

The patient acceptable symptom state for knee pain - a systematic literature review and meta-analysis (2021)
Journal Article
Georgopoulos, V., Smith, S., McWilliams, D., Vincent, T., Watt, F., & Walsh, D. (2021). The patient acceptable symptom state for knee pain - a systematic literature review and meta-analysis. Osteoarthritis and Cartilage, 29(Suppl. 1), S52. https://doi.org/10.1016/j.joca.2021.02.076

Purpose: Knee pain is highly prevalent, most commonly attributed to osteoarthritis in older people, and in younger people often due to internal derangements. Knee pain can be measured using numerical patient-reported outcome measures (PROMs). Several... Read More about The patient acceptable symptom state for knee pain - a systematic literature review and meta-analysis.

Can patient characteristics explain variance in ultrasound strain elastography measures of the quadratus femoris and patellar tendons? (2021)
Journal Article
Dickson, D. M., Smith, S. L., & Hendry, G. J. (2021). Can patient characteristics explain variance in ultrasound strain elastography measures of the quadratus femoris and patellar tendons?. Knee, 28, 282-293. https://doi.org/10.1016/j.knee.2020.12.011

Objectives To explore the associations between participant characteristics and magnitudes of difference in paired elastography measures of knee tendon from different ultrasound systems, and to compare strain elastography pattern description. Material... Read More about Can patient characteristics explain variance in ultrasound strain elastography measures of the quadratus femoris and patellar tendons?.

Intermachine Variation of Ultrasound Strain Elastographic Measures of the Quadriceps and Patellar Tendons in Healthy Participants: Implications for Clinical Practice (2020)
Journal Article
Dickson, D. M., Fawole, H. O., Hendry, G. J., & Smith, S. L. (2020). Intermachine Variation of Ultrasound Strain Elastographic Measures of the Quadriceps and Patellar Tendons in Healthy Participants: Implications for Clinical Practice. Journal of Ultrasound in Medicine, 39(7), 1343-1353. https://doi.org/10.1002/jum.15228

Objectives To evaluate intermachine variation and compare intraoperator and interoperator agreement and repeatability characteristics of 2 ultrasound (US) systems for measurements of quadriceps and patellar tendons by strain elastography (SE). Me... Read More about Intermachine Variation of Ultrasound Strain Elastographic Measures of the Quadriceps and Patellar Tendons in Healthy Participants: Implications for Clinical Practice.

Determining responsiveness and meaningful changes for the Musculoskeletal Health Questionnaire (MSK-HQ) for use across musculoskeletal care pathways (2019)
Journal Article
Price, A. J., Ogollah, R., Kang, S., Hay, E., Barker, K. L., Benedetto, E., …Hill, J. C. (2019). Determining responsiveness and meaningful changes for the Musculoskeletal Health Questionnaire (MSK-HQ) for use across musculoskeletal care pathways. BMJ Open, 9(10), 1-7. https://doi.org/10.1136/bmjopen-2018-025357

Objectives: We have previously developed and validated the Arthritis Research UK Musculoskeletal Health Questionnaire (MSK-HQ) for use across musculoskeletal care pathways, showing encouraging psychometric test results. The objective of this study wa... Read More about Determining responsiveness and meaningful changes for the Musculoskeletal Health Questionnaire (MSK-HQ) for use across musculoskeletal care pathways.

155?Sex-related differences in muscle co-activation in individuals with knee osteoarthritis (2019)
Journal Article
Smith, S. L., Woodburn, J., & Steultjens, M. P. M. (2019). 155?Sex-related differences in muscle co-activation in individuals with knee osteoarthritis. Rheumatology, 58(Issue Supplement 3), https://doi.org/10.1093/rheumatology/kez108.063

Background: Sex-related differences in muscle function have been well established in healthy individuals. In individuals with knee osteoarthritis (KOA), impairments in muscle function such as muscle weakness and high muscle co-activation have also be... Read More about 155?Sex-related differences in muscle co-activation in individuals with knee osteoarthritis.