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A Yeast-Based Functional Assay to Study Plant N-Degron – N-Recognin Interactions (2022)
Journal Article
Kozlic, A., Winter, N., Telser, T., Reimann, J., Rose, K., Nehlin, L., …Bachmair, A. (2022). A Yeast-Based Functional Assay to Study Plant N-Degron – N-Recognin Interactions. Frontiers in Plant Science, 12, Article 806129. https://doi.org/10.3389/fpls.2021.806129

The N-degron pathway is a branch of the ubiquitin-proteasome system where amino-terminal residues serve as degradation signals. In a synthetic biology approach, we expressed ubiquitin ligase PRT6 and ubiquitin conjugating enzyme 2 (AtUBC2) from Arabi... Read More about A Yeast-Based Functional Assay to Study Plant N-Degron – N-Recognin Interactions.

Oxygen Sensing Coordinates Photomorphogenesis to Facilitate Seedling Survival (2015)
Journal Article
Abbas, M., S, B., Rooney, D. J., Gibbs, D. J., Vicente Conde, J., Correia C, S., …MJ, H. (2015). Oxygen Sensing Coordinates Photomorphogenesis to Facilitate Seedling Survival. Current Biology, 25(11), 1483-1488. https://doi.org/10.1016/j.cub.2015.03.060

Successful emergence from the soil is essential for plant establishment in natural and farmed systems. It has been assumed that the absence of light in the soil is the preeminent signal perceived during early seedling development, leading to a distin... Read More about Oxygen Sensing Coordinates Photomorphogenesis to Facilitate Seedling Survival.

Group VII ethylene response factors coordinate oxygen and nitric oxide signal transduction and stress responses in plants (2015)
Journal Article
Gibbs, D. J., Vincente Conde, J., Berckhan, S., Prasad, G., Mendiondo, G. M., & Holdsworth, M. J. (2015). Group VII ethylene response factors coordinate oxygen and nitric oxide signal transduction and stress responses in plants. Plant Physiology, 169(1), https://doi.org/10.1104/pp.15.00338

The group VII ethylene response factors (ERFVIIs) are plant-specific transcription factors that have emerged as important regulators of abiotic and biotic stress responses, in particular, low-oxygen stress. A defining feature of ERFVIIs is their cons... Read More about Group VII ethylene response factors coordinate oxygen and nitric oxide signal transduction and stress responses in plants.

Nitric oxide sensing in plants is mediated by proteolytic control of Group VII ERF transcription factors (2014)
Journal Article
Gibbs, D. J., Md Isa, N., Movahedi, M., Lozano-Juste, J., Mendiondo, G. M., Berckhan, S., …Holdsworth, M. J. (2014). Nitric oxide sensing in plants is mediated by proteolytic control of Group VII ERF transcription factors. Molecular Cell, 53(3), https://doi.org/10.1016/j.molcel.2013.12.020

Nitric oxide (NO) is an important signaling compound in prokaryotes and eukaryotes. In plants, NO regulates critical developmental transitions and stress responses. Here, we identify a mechanism for NO sensing that coordinates responses throughout de... Read More about Nitric oxide sensing in plants is mediated by proteolytic control of Group VII ERF transcription factors.