All Outputs (26)

Detecting iodine deficiency risks from dietary transitions using shopping data (2024)
Journal Article
Mansilla, R., Long, G., Welham, S., Harvey, J., Lukinova, E., Nica-Avram, G., …Goulding, J. (2024). Detecting iodine deficiency risks from dietary transitions using shopping data. Scientific Reports, 14(1), Article 1017. https://doi.org/10.1038/s41598-023-50180-7

Plant-based product replacements are gaining popularity. However, the long-term health implications remain poorly understood, and available methods, though accurate, are expensive and burdensome, impeding the study of sufficiently large cohorts. To i... Read More about Detecting iodine deficiency risks from dietary transitions using shopping data.

Who consumes anthocyanins and anthocyanidins? Mining national retail data to reveal the influence of socioeconomic deprivation and seasonality on polyphenol dietary intake (2023)
Conference Proceeding
Harvey, J., Long, G., Welham, S., Mansilla, R., Rose, P., Thomas, M., …Goulding, J. (2023). Who consumes anthocyanins and anthocyanidins? Mining national retail data to reveal the influence of socioeconomic deprivation and seasonality on polyphenol dietary intake. In Proceedings: 2023 IEEE International Conference on Big Data (BigData) (4530-4538). https://doi.org/10.1109/BigData59044.2023.10386220

Anthocyanins are a class of polyphenols that have received widespread recent attention due to their potential health benefits. However, estimating the dietary intake of anthocyanins at a population level is a challenging task, due to the difficulty o... Read More about Who consumes anthocyanins and anthocyanidins? Mining national retail data to reveal the influence of socioeconomic deprivation and seasonality on polyphenol dietary intake.

Adoption of a Short-Term (4-Week) Vegan Diet as Part of ‘Veganuary’ Significantly Reduces Saturated Fatty Acid (SFA), Cholesterol, B12, and Iodine Intake in Omnivorous Individuals—An Observational Study (2023)
Journal Article
Eveleigh, E., Coneyworth, L., Craigon, J., & Welham, S. (2023). Adoption of a Short-Term (4-Week) Vegan Diet as Part of ‘Veganuary’ Significantly Reduces Saturated Fatty Acid (SFA), Cholesterol, B12, and Iodine Intake in Omnivorous Individuals—An Observational Study. Nutrients, 15(23), Article 4967. https://doi.org/10.3390/nu15234967

Global veganism campaigns like ‘Veganuary’ have gained popularity. We conducted an observational study to assess the impact of a 4-week vegan diet during ‘Veganuary’ on nutrient intake, status, knowledge, and motivations for veganism. Data were colle... Read More about Adoption of a Short-Term (4-Week) Vegan Diet as Part of ‘Veganuary’ Significantly Reduces Saturated Fatty Acid (SFA), Cholesterol, B12, and Iodine Intake in Omnivorous Individuals—An Observational Study.

Mineral supplements in Aging (2023)
Book Chapter
Welham, S., Rose, P., Coneyworth, L., Avery, A., & Kirk, C. (in press). Mineral supplements in Aging. In Biochemistry and Cell Biology of Ageing: Part V, Anti-ageing Interventions. Switzerland: Springer

With advancing age, achievement of dietary adequacy for all nutrients is increasingly difficult and this is particularly so for minerals. Various factors impede mineral acquisition and absorption including reduced appetite, depressed gastric acid pro... Read More about Mineral supplements in Aging.

Update on the global prevalence and severity of kiwifruit allergy: a scoping review (2023)
Journal Article
James, C. A., Welham, S., & Rose, P. (2023). Update on the global prevalence and severity of kiwifruit allergy: a scoping review. International Journal of Food Science and Technology, 58(12), 6158-6181. https://doi.org/10.1111/ijfs.16680

The production and use of kiwifruit, and their derived products, has seen rapid growth in the food industry with some 4,467,099 tonnes produced in 2021. A key area of development has been the increased use of kiwifruit waste streams to support sustai... Read More about Update on the global prevalence and severity of kiwifruit allergy: a scoping review.

The Impact of Drugs on Hydrogen Sulfide Homeostasis in Mammals (2023)
Journal Article
Alsaeedi, A., Welham, S., Rose, P., & Zhu, Y. (2023). The Impact of Drugs on Hydrogen Sulfide Homeostasis in Mammals. Antioxidants, 12(4), Article 908. https://doi.org/10.3390/antiox12040908

Mammalian cells and tissues have the capacity to generate hydrogen sulfide gas (H2S) via catabolic routes involving cysteine metabolism. H2S acts on cell signaling cascades that are necessary in many biochemical and physiological roles important in t... Read More about The Impact of Drugs on Hydrogen Sulfide Homeostasis in Mammals.

The Role of Micronutrients and Micronutrient Supplements in Vegetarian and Vegan Diets (2023)
Book Chapter
Eveleigh, E., Coneyworth, L., & Welham, S. (2023). The Role of Micronutrients and Micronutrient Supplements in Vegetarian and Vegan Diets. In Dietary Supplements - Challenges and Future Research. InTech. https://doi.org/10.5772/intechopen.109595

Vegetarian and vegan diets are becoming increasingly popular in Western countries. Numerous global nutrition bodies advocate that appropriately planned meat-free diets are suitable for all the life cycle stages. Nutritionally adequate vegetarian and... Read More about The Role of Micronutrients and Micronutrient Supplements in Vegetarian and Vegan Diets.

Systematic review and meta-analysis of iodine nutrition in modern vegan and vegetarian diets (2023)
Journal Article
Eveleigh, E., Coneyworth, L., & Welham, S. (2023). Systematic review and meta-analysis of iodine nutrition in modern vegan and vegetarian diets. British Journal of Nutrition, 130(9), 1580-1594. https://doi.org/10.1017/S000711452300051X

Vegan and vegetarian diets are widely supported and adopted, but individuals following such diets remain at greater risk of iodine deficiency. This systematic review and meta-analysis was conducted to assess the iodine intake and status in adults fol... Read More about Systematic review and meta-analysis of iodine nutrition in modern vegan and vegetarian diets.

The importance of m6A topology in chicken embryo mRNA: a precise mapping of m6A at the conserved chicken β-actin zipcode (2023)
Journal Article
Baron, F., Zhang, M., Archer, N., Bellows, E., Knight, H. M., Welham, S., …Bodi, Z. (2023). The importance of m6A topology in chicken embryo mRNA: a precise mapping of m6A at the conserved chicken β-actin zipcode. RNA, 29(6), 777-789. https://doi.org/10.1261/rna.079615.123

N6-methyladenosine (m6A) in mRNA regulates almost every stage in the mRNA life cycle, and the development of methodologies for the high-throughput detection of methylated sites in mRNA using m6A-specific methylated RNA immunoprecipitation with next-g... Read More about The importance of m6A topology in chicken embryo mRNA: a precise mapping of m6A at the conserved chicken β-actin zipcode.

Impact of lifestyle factors on dietary vitamin B6 intake and plasma pyridoxal 5'-phosphate level in UK adults: National Diet and Nutrition Survey Rolling Programme (NDNS) (2008-2017) (2023)
Journal Article
Alsaeedi, A., Welham, S., & Rose, P. (2023). Impact of lifestyle factors on dietary vitamin B6 intake and plasma pyridoxal 5'-phosphate level in UK adults: National Diet and Nutrition Survey Rolling Programme (NDNS) (2008-2017). British Journal of Nutrition, 130(8), 1403-1415. https://doi.org/10.1017/S0007114523000417

Reduction in dietary vitamin B6 intakes is associated with increased relative risk of diseases such as cancer, atherosclerosis, and cognitive dysfunction. All forms of dietary vitamin B6 are converted to pyridoxal 5'-phosphate (PLP), that is needed f... Read More about Impact of lifestyle factors on dietary vitamin B6 intake and plasma pyridoxal 5'-phosphate level in UK adults: National Diet and Nutrition Survey Rolling Programme (NDNS) (2008-2017).

Environmental and farming practice controls of productivity of Cyrtosperma merkusii (giant swamp taro), an underutilised wetland and potential paludiculture crop (2023)
Journal Article
Mendiondo, G., Moko, E. M., Sparkes, D. L., Rahardiyan, D., Welham, S. J. M., O'Reilly, P., …Sjögersten, S. (2023). Environmental and farming practice controls of productivity of Cyrtosperma merkusii (giant swamp taro), an underutilised wetland and potential paludiculture crop. Food and Energy Security, 13(1), Article e490. https://doi.org/10.1002/fes3.490

Growing recognition of the potential vulnerabilities of major crop systems has spurred a growing interest in the potential of alternative crops which may be resilient to climate change and also help mitigate its effects. In Indonesia, such issues are... Read More about Environmental and farming practice controls of productivity of Cyrtosperma merkusii (giant swamp taro), an underutilised wetland and potential paludiculture crop.

The Impact of the COVID-19 Pandemic on the Food Security of UK Adults Aged 20–65 Years (COVID-19 Food Security and Dietary Assessment Study) (2022)
Journal Article
Thomas, M., Eveleigh, E., Vural, Z., Rose, P., Avery, A., Coneyworth, L., & Welham, S. (2022). The Impact of the COVID-19 Pandemic on the Food Security of UK Adults Aged 20–65 Years (COVID-19 Food Security and Dietary Assessment Study). Nutrients, 14(23), Article 5078. https://doi.org/10.3390/nu14235078

The first UK lockdown greatly impacted the food security status of UK adults. This study set out to establish if food procurement was adapted differently for different income groups and if this impacted dietary intakes disproportionately. Adults (n=5... Read More about The Impact of the COVID-19 Pandemic on the Food Security of UK Adults Aged 20–65 Years (COVID-19 Food Security and Dietary Assessment Study).

Edible algae allergenicity – a short report (2022)
Journal Article
James, C. A., Welham, S., & Rose, P. (2023). Edible algae allergenicity – a short report. Journal of Applied Phycology, 35(1), 339–352. https://doi.org/10.1007/s10811-022-02880-2

The use of seaweed and algal derived products in the food industry has grown rapidly in recent times. Major areas of expansion have been in Western countries where algal derived commodities are being utilised as edible foods or sources of high value... Read More about Edible algae allergenicity – a short report.

Influence of income on diet quality and daily iron and zinc intake: Analysis of the National Diet and Nutrition Survey of British females aged 11-14 and 15-18 years (2022)
Journal Article
Thomas, M., Coneyworth, L., & Welham, S. (2023). Influence of income on diet quality and daily iron and zinc intake: Analysis of the National Diet and Nutrition Survey of British females aged 11-14 and 15-18 years. European Journal of Nutrition, 62(1), 499–510. https://doi.org/10.1007/s00394-022-03000-z

Purpose: A negative socio-economic gradient exists for diet and health outcomes. Since cheaper diets are associated with increased energy and lower nutrient density, we investigated the influence of income on iron and zinc intakes and overall diet qu... Read More about Influence of income on diet quality and daily iron and zinc intake: Analysis of the National Diet and Nutrition Survey of British females aged 11-14 and 15-18 years.

Vegans and vegetarians living in Nottingham (UK) continue to be at risk of iodine deficiency (2022)
Journal Article
Eveleigh, E., Coneyworth, L., Zhou, M., Burdett, H., Malla, J., Nguyen, V. H., & Welham, S. (2023). Vegans and vegetarians living in Nottingham (UK) continue to be at risk of iodine deficiency. British Journal of Nutrition, 129(9), 1510-1527. https://doi.org/10.1017/S0007114522000113

Iodine is essential for thyroid hormone synthesis. Individuals adhering to vegan and vegetarian diets have been found to be vulnerable to iodine deficiency. Yet, iodine has not been monitored in these groups across time. This study aims to investigat... Read More about Vegans and vegetarians living in Nottingham (UK) continue to be at risk of iodine deficiency.

Vegans, Vegetarians, and Omnivores: How Does Dietary Choice Influence Iodine Intake? A Systematic Review (2020)
Journal Article
Eveleigh, E., Coneyworth, L. J., Avery, A., & Welham, S. J. (2020). Vegans, Vegetarians, and Omnivores: How Does Dietary Choice Influence Iodine Intake? A Systematic Review. Nutrients, 12(6), https://doi.org/10.3390/nu12061606

Vegan and vegetarian diets are becoming increasingly popular. Dietary restrictions may increase the risk of iodine deficiency. This systematic review aims to assess iodine intake and status in adults following a vegan or vegetarian diet in industrial... Read More about Vegans, Vegetarians, and Omnivores: How Does Dietary Choice Influence Iodine Intake? A Systematic Review.

Trace Mineral Intake and Deficiencies in Older Adults Living in the Community and Institutions: A Systematic Review (2020)
Journal Article
Welham, S. J. M., Vural, Z., Avery, A., Kalogiros, D. I., Coneyworth, L. J., & Welham, S. J. (2020). Trace Mineral Intake and Deficiencies in Older Adults Living in the Community and Institutions: A Systematic Review. Nutrients, 12(4), https://doi.org/10.3390/nu12041072

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. The global population is ageing with many older adults suffering from age-related malnutrition, including micronutrient deficiencies. Adequate nutrient intake is vital to enable older adults t... Read More about Trace Mineral Intake and Deficiencies in Older Adults Living in the Community and Institutions: A Systematic Review.

Geographical and seasonal variation in Iodine content of cow’s milk in the UK and consequences for the consumer´s supply (2020)
Journal Article
Coneyworth, L. J., Welham, S. J., Coulthard, L. C., Bailey, E. H., Young, S. D., Stubberfield, J., …Homer, E. M. (2020). Geographical and seasonal variation in Iodine content of cow’s milk in the UK and consequences for the consumer´s supply. Journal of Trace Elements in Medicine and Biology, 59, Article 126453. https://doi.org/10.1016/j.jtemb.2020.126453

Background. Dairy products provide a crucial source of dietary iodine for the majority of the UK population, contributing approximately 30-40 % of daily intake. Fluctuations in the iodine content of purchased milk both seasonally and annually implies... Read More about Geographical and seasonal variation in Iodine content of cow’s milk in the UK and consequences for the consumer´s supply.

LIM kinase function and renal growth: potential role for LIM kinases in fetal programming of kidney development (2017)
Journal Article
Sparrow, A. J., Sweetman, D., & Welham, S. J. (2017). LIM kinase function and renal growth: potential role for LIM kinases in fetal programming of kidney development. Life Sciences, 186, 17-24. https://doi.org/10.1016/j.lfs.2017.07.034

Aims Maternal dietary restriction during pregnancy impairs nephron development and results in offspring with fewer nephrons. Cell turnover in the early developing kidney is altered by exposure to maternal dietary restriction and may be regulated b... Read More about LIM kinase function and renal growth: potential role for LIM kinases in fetal programming of kidney development.

Acetylsalicylic acid interferes with embryonic kidney growth and development by a prostaglandin-independent mechanism (2017)
Journal Article
Welham, S. J., Sparrow, A. J., Gardner, D. S., & Elmes, M. J. (2017). Acetylsalicylic acid interferes with embryonic kidney growth and development by a prostaglandin-independent mechanism. World Journal of Nephrology, 6(1), https://doi.org/10.5527/WJN.v6.i1.21

AIM: To evaluate the effects of the non-selective, non-steroidal anti-inflammatory drug (NSAID) acetylsalicylic acid (ASA), on ex vivo embryonic kidney growth and development. METHODS: Pairs of fetal mouse kidneys at embryonic day 12.5 were cultured... Read More about Acetylsalicylic acid interferes with embryonic kidney growth and development by a prostaglandin-independent mechanism.