All Outputs (2)

The antimalarial drug primaquine targets Fe–S cluster proteins and yeast respiratory growth (2015)
Journal Article
Lalève, A., Vallieres, C., Golinelli-Cohen, M., Bouton, C., Song, Z., Pawlik, G., …Meunier, B. (2016). The antimalarial drug primaquine targets Fe–S cluster proteins and yeast respiratory growth. Redox Biology, 7, https://doi.org/10.1016/j.redox.2015.10.008

Malaria is a major health burden in tropical and subtropical countries. The antimalarial drug primaquine is extremely useful for killing the transmissible gametocyte forms of Plasmodium falciparum and the hepatic quiescent forms of P. vivax. Yet its... Read More about The antimalarial drug primaquine targets Fe–S cluster proteins and yeast respiratory growth.

Novel, synergistic antifungal combinations that target translation fidelity (2015)
Journal Article
Moreno-Martinez, E., Vallieres, C., Holland, S. L., & Avery, S. V. (in press). Novel, synergistic antifungal combinations that target translation fidelity. Scientific Reports, 5(16700), https://doi.org/10.1038/srep16700

There is an unmet need for new antifungal or fungicide treatments, as resistance to existing treatments grows. Combination treatments help to combat resistance. Here we develop a novel, effective target for combination antifungal therapy. Different a... Read More about Novel, synergistic antifungal combinations that target translation fidelity.