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Signature-tagged transposon mutagenesis identifies novel mycobacterium tuberculosis genes involved in the parasitism of human macrophages (2006)
Journal Article
mycobacterium tuberculosis genes involved in the parasitism of human macrophages. Infection and Immunity, 75(1), doi:10.1128/IAI.00058-06. ISSN 0019-9567

Using signature-tagged transposon mutagenesis, we isolated 23 Mycobacterium tuberculosis mutants, corresponding to 21 genes or genetic regions, attenuated in their ability to parasitize human macrophages. Mutants disrupted in the ABC transporter-enco... Read More