Skip to main content

Research Repository

Advanced Search

All Outputs (71)

Association study of human leukocyte antigen (HLA) variants and idiopathic pulmonary fibrosis (2023)
Journal Article
Guillen-Guio, B., Paynton, M. L., Allen, R. J., Chin, D. P., Donoghue, L. J., Stockwell, A., …Hollox, E. J. (in press). Association study of human leukocyte antigen (HLA) variants and idiopathic pulmonary fibrosis. ERJ Open Research, 00553-2023. https://doi.org/10.1183/23120541.00553-2023

IntroductionIdiopathic pulmonary fibrosis (IPF) is a chronic interstitial pneumonia marked by progressive lung fibrosis and a poor prognosis. Recent studies have highlighted the potential role of infection in the pathogenesis of IPF and a prior assoc... Read More about Association study of human leukocyte antigen (HLA) variants and idiopathic pulmonary fibrosis.

COVID-19 infection, admission and death and the impact of corticosteroids amongst people with rare autoimmune rheumatic disease during the second wave of covid-19 in England: results from the RECORDER Project (2023)
Journal Article
Rutter, M., Lanyon, P. C., Grainge, M. J., Hubbard, R., Bythell, M., Stilwell, P., …Pearce, F. A. (2023). COVID-19 infection, admission and death and the impact of corticosteroids amongst people with rare autoimmune rheumatic disease during the second wave of covid-19 in England: results from the RECORDER Project. Rheumatology, 62(12), 3828-3837. https://doi.org/10.1093/rheumatology/kead150

Objectives To calculate the rates of COVID-19 infection and COVID-19-related death among people with rare autoimmune rheumatic diseases (RAIRD) during the second wave of the COVID-19 pandemic in England, and describe the impact of corticosteroids on... Read More about COVID-19 infection, admission and death and the impact of corticosteroids amongst people with rare autoimmune rheumatic disease during the second wave of covid-19 in England: results from the RECORDER Project.

The Impact of COVID-19 on Lung Cancer Incidence in England: Analysis of the National Lung Cancer Audit 2019 and 2020 Rapid Cancer Registration Datasets (2023)
Journal Article
Gysling, S., Morgan, H., Ifesemen, O. S., West, D., Conibear, J., Navani, N., …Hubbard, R. (2023). The Impact of COVID-19 on Lung Cancer Incidence in England: Analysis of the National Lung Cancer Audit 2019 and 2020 Rapid Cancer Registration Datasets. Chest, 163(6), 1599-1607. https://doi.org/10.1016/j.chest.2023.01.008

Background: The COVID-19 pandemic has caused significant disruption to health-care services and delivery worldwide. The impact of the pandemic and associated national lockdowns on lung cancer incidence in England have yet to be assessed. Research Que... Read More about The Impact of COVID-19 on Lung Cancer Incidence in England: Analysis of the National Lung Cancer Audit 2019 and 2020 Rapid Cancer Registration Datasets.

Are people with mesothelioma who respond to the English Cancer Patient Experience Survey representative of the national mesothelioma population? A data comparison with cancer registry patients from the National Lung Cancer Audit (2022)
Journal Article
Nartey, Y., Stewart, I., Beattie, V., Wilcock, A., Beckett, P., Hubbard, R., & Tata, L. J. (2022). Are people with mesothelioma who respond to the English Cancer Patient Experience Survey representative of the national mesothelioma population? A data comparison with cancer registry patients from the National Lung Cancer Audit. International Journal of Nursing Studies Advances, 4, Article 100077. https://doi.org/10.1016/j.ijnsa.2022.100077

Introduction: More than 2,700 people are diagnosed with mesothelioma each year in the UK. Survival from mesothelioma is poor and to ensure service users’ perspectives are incorporated in designing the most effective strategies to improve healthcare i... Read More about Are people with mesothelioma who respond to the English Cancer Patient Experience Survey representative of the national mesothelioma population? A data comparison with cancer registry patients from the National Lung Cancer Audit.

Using patient experiences to evaluate care and expectations in lung cancer: analysis of the English Cancer Patient Experience Survey linked with the national cancer registry (2022)
Journal Article
Nartey, Y., Tata, L. J., Khakwani, A., Beattie, V., Beckett, P., Hubbard, R. B., & Stewart, I. (2022). Using patient experiences to evaluate care and expectations in lung cancer: analysis of the English Cancer Patient Experience Survey linked with the national cancer registry. Supportive Care in Cancer, 30(5), 4417-4428. https://doi.org/10.1007/s00520-022-06863-4

Purpose: Identification of unmet needs in person centred and supportive care could be limited by differences in experience across specific cancer populations. Using the experiences of people with lung cancer, we assess distinctions according to demog... Read More about Using patient experiences to evaluate care and expectations in lung cancer: analysis of the English Cancer Patient Experience Survey linked with the national cancer registry.

Selection of eligible participants for screening for lung cancer using primary care data (2021)
Journal Article
O’Dowd, E. L., Ten Haaf, K., Kaur, J., Duffy, S. W., Hamilton, W., Hubbard, R. B., …Baldwin, D. R. (2022). Selection of eligible participants for screening for lung cancer using primary care data. Thorax, 77(9), 882-890. https://doi.org/10.1136/thoraxjnl-2021-217142

Lung cancer screening is effective if offered to people at increased risk of the disease. Currently, direct contact with potential participants is required for evaluating risk. A way to reduce the number of ineligible people contacted might be to app... Read More about Selection of eligible participants for screening for lung cancer using primary care data.

COVID-19 infection, admission and death among people with rare autoimmune rheumatic disease in England: results from the RECORDER project (2021)
Journal Article
Rutter, M., Lanyon, P. C., Grainge, M. J., Hubbard, R., Peach, E., Bythell, M., …Pearce, F. A. (2022). COVID-19 infection, admission and death among people with rare autoimmune rheumatic disease in England: results from the RECORDER project. Rheumatology, 61(8), 3161-3171. https://doi.org/10.1093/rheumatology/keab794

Objectives: To calculate the rates of COVID-19 infection and COVID-19-related death among people with rare autoimmune rheumatic diseases (RAIRD) during the first wave of the COVID-19 pandemic in England compared to the general population. Methods... Read More about COVID-19 infection, admission and death among people with rare autoimmune rheumatic disease in England: results from the RECORDER project.

36-month evaluation of a weight management programme in Chinese overweight and obese adults (2021)
Journal Article
Yang, X., Chattopadhyay, K., Hubbard, R., Li, J., Li, L., & Lin, Y. (2021). 36-month evaluation of a weight management programme in Chinese overweight and obese adults. Frontiers in Public Health, 9, Article 749302

Background: Few comprehensive lifestyle intervention programmes have been investigated on overweight and obese adults in China. This study was to evaluate the effect of a 36-month weight management programme on weight loss and its maintenance among o... Read More about 36-month evaluation of a weight management programme in Chinese overweight and obese adults.

What is the Definition of Cure in Non-small Cell Lung Cancer? (2021)
Journal Article
Morgan, H., Ellis, L., O’Dowd, E. L., Murray, R. L., Hubbard, R., & Baldwin, D. R. (2021). What is the Definition of Cure in Non-small Cell Lung Cancer?. Oncology and Therapy, 9(2), 365-371. https://doi.org/10.1007/s40487-021-00163-3

The concept of cure from cancer is important to patients, but can be difficult to communicate in terms that are meaningful. This is because there are a number of definitions of cure that are applied by clinicians, patients and the public, and by poli... Read More about What is the Definition of Cure in Non-small Cell Lung Cancer?.

Factors associated with survival in small cell lung cancer: an analysis of real-world national audit, chemotherapy and radiotherapy data (2021)
Journal Article
Jones, G. S., Khakwani, A., Pascoe, A., Foweraker, K., McKeever, T. M., Hubbard, R. B., & Baldwin, D. R. (2021). Factors associated with survival in small cell lung cancer: an analysis of real-world national audit, chemotherapy and radiotherapy data. Annals of Palliative Medicine, 10(4), 4055-4068. https://doi.org/10.21037/apm-20-1824

Background: The mainstay of treatment for small cell lung cancer (SCLC) involves platinum doublet chemotherapy but the optimal duration, 4 vs. 6 cycles, is not known. Concurrent thoracic radiotherapy followed by prophylactic cranial irradiation (PCI)... Read More about Factors associated with survival in small cell lung cancer: an analysis of real-world national audit, chemotherapy and radiotherapy data.

Worldwide relative smoking prevalence among people living with and without HIV: a systematic review and meta-analysis (2021)
Journal Article
Johnston, P. I., Wright, S. W., Orr, M., Pearce, F. A., Stevens, J. W., Hubbard, R. B., & Collini, P. J. (2021). Worldwide relative smoking prevalence among people living with and without HIV: a systematic review and meta-analysis. AIDS, 35(6), 957-970. https://doi.org/10.1097/QAD.0000000000002815

Objective and design: People living with HIV (PLH) suffer disproportionately from the chronic diseases exacerbated by smoking tobacco. We performed a systematic review and meta-analysis to establish the relative prevalence of smoking among PLH. M... Read More about Worldwide relative smoking prevalence among people living with and without HIV: a systematic review and meta-analysis.

Risk of death among people with rare autoimmune diseases compared with the general population in England during the 2020 COVID-19 pandemic (2020)
Journal Article
Peach, E., Rutter, M., Lanyon, P., Grainge, M. J., Hubbard, R., Aston, J., …Pearce, F. (2021). Risk of death among people with rare autoimmune diseases compared with the general population in England during the 2020 COVID-19 pandemic. Rheumatology, 60(4), 1902–1909. https://doi.org/10.1093/rheumatology/keaa855

Objectives: To quantify the risk of death among people with rare autoimmune rheumatic diseases (RAIRD) during the UK 2020 COVID-19 pandemic compared with the general population, and compared with their pre-COVID risk. Methods: We conducted a cohort s... Read More about Risk of death among people with rare autoimmune diseases compared with the general population in England during the 2020 COVID-19 pandemic.

Do working practices of cancer nurse specialists improve clinical outcomes? Retrospective cohort analysis from the English National Lung Cancer Audit (2020)
Journal Article
Stewart, I., Leary, A., Khakwani, A., Borthwick, D., Tod, A., Hubbard, R., …Tata, L. J. (2021). Do working practices of cancer nurse specialists improve clinical outcomes? Retrospective cohort analysis from the English National Lung Cancer Audit. International Journal of Nursing Studies, 118, Article 103718. https://doi.org/10.1016/j.ijnurstu.2020.103718

Background Cancer nurse specialists are advanced practitioners who offer continuity of care and expert support for people diagnosed with specific cancers. Health Education England's Cancer Workforce Plan prioritises expansion of cancer nurse special... Read More about Do working practices of cancer nurse specialists improve clinical outcomes? Retrospective cohort analysis from the English National Lung Cancer Audit.

A systematic review of survival following anti-cancer treatment for small cell lung cancer (2020)
Journal Article
Baldwin, D. R., Jones, G. S., Elimian, K., Hubbard, R. B., & McKeever, T. M. (2020). A systematic review of survival following anti-cancer treatment for small cell lung cancer. Lung Cancer, 141, 44-55. https://doi.org/10.1016/j.lungcan.2019.12.015

Objectives: We conducted a systematic review and meta-analysis of survival following treatment recommended by the European Society of Medical Oncology for SCLC in order to determine a benchmark for novel therapies to be compared with. Materials and m... Read More about A systematic review of survival following anti-cancer treatment for small cell lung cancer.

Is the English Cancer Patient Experience Survey representative? A comparative analysis with the National Lung Cancer Audit (2019)
Journal Article
Nartey, Y., Stewart, I., Khakwani, A., Beattie, V., Wilcock, A., Woolhouse, I., …Tata, L. J. (2020). Is the English Cancer Patient Experience Survey representative? A comparative analysis with the National Lung Cancer Audit. Lung Cancer, 140, 27-34. https://doi.org/10.1016/j.lungcan.2019.11.023

© 2019 Elsevier B.V. Objectives: Healthcare systems increasingly recognise the importance of service users’ perspectives for improving care organisation and delivery. The English Cancer Patient Experience Survey (CPES) is carried out annually, howeve... Read More about Is the English Cancer Patient Experience Survey representative? A comparative analysis with the National Lung Cancer Audit.

Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis (2019)
Journal Article
Allen, R. J., Guillen-Guio, B., Oldham, J. M., Ma, S., Dressen, A., Paynton, M. L., …Wain, L. V. (2020). Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine, 201(5), 564-574. https://doi.org/10.1164/rccm.201905-1017oc

RATIONALE: Idiopathic pulmonary fibrosis (IPF) is a complex lung disease characterised by scarring of the lung that is believed to result from an atypical response to injury of the epithelium. Genome-wide association studies have reported signals of... Read More about Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis.

Factors influencing treatment selection and thirty-day mortality following chemotherapy for people with small cell lung cancer: an analysis of national audit data (2018)
Journal Article
Jones, G. S., McKeever, T. M., Hubbard, R. B., Khakwani, A., & Baldwin, D. R. (2018). Factors influencing treatment selection and thirty-day mortality following chemotherapy for people with small cell lung cancer: an analysis of national audit data. European Journal of Cancer, 103, 176-183. https://doi.org/10.1016/j.ejca.2018.07.133

Background Thirty-day mortality after treatment for lung cancer is a measure of unsuccessful outcome and where treatment should have been avoided. Guidelines recommend offering chemotherapy to individuals with small cell lung cancer (SCLC) who ha... Read More about Factors influencing treatment selection and thirty-day mortality following chemotherapy for people with small cell lung cancer: an analysis of national audit data.

Barriers to delivering advanced cancer nursing: a workload analysis of specialist nurse practice linked to the English National Lung Cancer Audit (2018)
Journal Article
Stewart, I., Leary, A., Tod, A., Borthwick, D., Khakwani, A., Hubbard, R., …Tata, L. (2018). Barriers to delivering advanced cancer nursing: a workload analysis of specialist nurse practice linked to the English National Lung Cancer Audit. European Journal of Oncology Nursing, 36, 103-111. https://doi.org/10.1016/j.ejon.2018.07.006

Purpose: Health services across the world utilise advanced practice in cancer care. In the UK, lung cancer nurse specialists (LCNS) are recognised as key components of quality care in national guidelines, yet access to LCNS contact is unequal and som... Read More about Barriers to delivering advanced cancer nursing: a workload analysis of specialist nurse practice linked to the English National Lung Cancer Audit.