All Outputs (7)

Longitudinal assessment of circulating insulin-like peptide 3 levels in healthy peripubertal girls (2014)
Journal Article
Hagen, C. P., Mieritz, M. G., Nielsen, J. E., Anand-Ivell, R., Ivell, R., & Juul, A. (2015). Longitudinal assessment of circulating insulin-like peptide 3 levels in healthy peripubertal girls. Fertility and Sterility, 103(3), https://doi.org/10.1016/j.fertnstert.2014.11.014

Objective: To elucidate the natural course of circulating insulin-like peptide 3 (INSL3) levels according to puberty as well as its relation to other reproductive hormones. Design: Population-based cohort study. Setting: Not applicable. Patient(s)... Read More about Longitudinal assessment of circulating insulin-like peptide 3 levels in healthy peripubertal girls.

Amniotic fluid phthalate levels and male fetal gonad function (2014)
Journal Article
Jensen, M. S., Anand-Ivell, R., Nørgaard-Pedersen, B., Jönsson, B. A., Bonde, J. P., Hougaard, D. M., …Toft, G. (2015). Amniotic fluid phthalate levels and male fetal gonad function. Epidemiology, 26(1), 91-99. https://doi.org/10.1097/EDE.0000000000000198

Background: Prenatal exposure to phthalates may pose a threat to human male reproduction. However, additional knowledge about the in vivo effect in humans is needed, and reported associations with genital abnormalities are inconclusive. We aimed to s... Read More about Amniotic fluid phthalate levels and male fetal gonad function.

Cryptorchidism in the orl rat is associated with muscle patterning defects in the fetal gubernaculum and altered hormonal signaling (2014)
Journal Article
Barthold, J. S., Robbins, A., Wang, Y., Pugarelli, J., Mateson, A., ANAND-IVELL, R., …Akins, R. E. (2014). Cryptorchidism in the orl rat is associated with muscle patterning defects in the fetal gubernaculum and altered hormonal signaling. Biology of Reproduction, 91(2), Article 41. https://doi.org/10.1095/biolreprod.114.119560

Cryptorchidism in the orl rat is associated with muscle patterning defects in the fetal gubernaculum and altered hormonal signaling (2014)
Journal Article
Barthold, J. S., Robbins, A., Wang, Y., Pugarelli, J., Mateson, A., Anand-Ivell, R., …Akins, R. E. J. (2014). Cryptorchidism in the orl rat is associated with muscle patterning defects in the fetal gubernaculum and altered hormonal signaling. Biology of Reproduction, 91(2), https://doi.org/10.1095/biolreprod.114.119560

Cryptorchidism, or undescended testis, is a common male genital anomaly of unclear etiology. Hormonal stimulation of the developing fetal gubernaculum by testicular androgens and insulin-like 3 (INSL3) is required for testicular descent. In studies o... Read More about Cryptorchidism in the orl rat is associated with muscle patterning defects in the fetal gubernaculum and altered hormonal signaling.

Insulin-like factor 3 and the HPG axis in the male (2014)
Journal Article
Ivell, R., Heng, K., & Anand-Ivell, R. (in press). Insulin-like factor 3 and the HPG axis in the male. Frontiers in Endocrinology, 5(6), https://doi.org/10.3389/fendo.2014.00006

The hypothalamic–pituitary–gonadal (HPG) axis comprises pulsatile GnRH from the hypothalamus impacting on the anterior pituitary to induce expression and release of both LH and FSH into the circulation. These in turn stimulate receptors on testicular... Read More about Insulin-like factor 3 and the HPG axis in the male.

Serum levels of insulin-like factor 3, anti-Müllerian hormone, inhibin B, and testosterone during pubertal transition in healthy boys: a longitudinal pilot study (2014)
Journal Article
Johansen, M. L., Anand-Ivell, R., Mouritsen, A., Hagen, C. P., Mieritz, M. G., Søeborg, T., …Juul, A. (2014). Serum levels of insulin-like factor 3, anti-Müllerian hormone, inhibin B, and testosterone during pubertal transition in healthy boys: a longitudinal pilot study. Reproduction, 147, https://doi.org/10.1530/REP-13-0435

Insulin-like factor 3 (INSL3) is a promising marker of Leydig cell function with potentially high clinical relevance. Limited data of INSL3 levels in relation to other reproductive hormones in healthy pubertal boys exist. In this study, we aimed to e... Read More about Serum levels of insulin-like factor 3, anti-Müllerian hormone, inhibin B, and testosterone during pubertal transition in healthy boys: a longitudinal pilot study.

Human Testicular Insulin-Like Factor 3 and Endocrine Disrupters (2014)
Book Chapter
Bay, K., & Anand-Ivell, R. (2014). Human Testicular Insulin-Like Factor 3 and Endocrine Disrupters. In Endocrine Disrupters (327-348). Elsevier. https://doi.org/10.1016/B978-0-12-800095-3.00012-2

The hormone insulin-like factor 3 (INSL3) is produced by testicular Leydig cells. Production of INSL3 is dependent on the state of Leydig cell differentiation and is stimulated by the long-term trophic effects of luteinizing hormone. INSL3 is, along... Read More about Human Testicular Insulin-Like Factor 3 and Endocrine Disrupters.